Uvavanyo lweHormone yeAnti-Müllerian
Umxholo
- Luyintoni uvavanyo lwe-anti-müllerian hormone (AMH)?
- Isetyenziselwa ntoni?
- Kutheni ndifuna uvavanyo lwe-AMH?
- Yintoni eyenzekayo ngexesha lovavanyo lwe-AMH?
- Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
- Ngaba bukhona ubungozi kuvavanyo?
- Zithetha ntoni iziphumo?
- Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-AMH?
- Izalathiso
Luyintoni uvavanyo lwe-anti-müllerian hormone (AMH)?
Olu vavanyo lilinganisa inqanaba le-anti-müllerian hormone (AMH) egazini. I-AMH yenziwa kwizicubu zokuzala zamadoda nabasetyhini. Indima ye-AMH kunye nokuba amanqanaba aqhelekileyo axhomekeke kubudala bakho nakwisini.
I-AMH idlala indima ebalulekileyo kuphuhliso lwamalungu esini kusana olungekazalwa. Ngexesha leeveki zokuqala zokukhulelwa, umntwana uya kuqala ukukhula amalungu okuzala. Usana luya kuba nemfuza ukuba ibe yindoda (i-XY genes) okanye eyasetyhini (i-XX genes).
Ukuba umntwana une-genes yamadoda (i-XY), amanqanaba aphezulu e-AMH ayenziwa, kunye namanye amahomoni angamadoda. Oku kuthintela ukukhula kwamalungu ababhinqileyo kwaye kukhuthaza ukuyilwa kwamalungu obudoda. Ukuba akukho ngokwaneleyo i-AMH yokumisa ukukhula kwamalungu ababhinqileyo, amalungu ezini ezesini anokwenza. Xa oku kusenzeka, amalungu esini wosana angangachazwa ngokucacileyo njengendoda okanye ibhinqa. Oku kwaziwa njenge-genitalia engaqondakaliyo. Elinye igama lale meko yi-intersex.
Ukuba usana olungekazalwa lunemfuza yabasetyhini (XX) isixa esincinci se-AMH senziwe. Oku kuvumela ukukhula kwamalungu okuzala ababhinqileyo. I-AMH inendima eyahlukileyo yabasetyhini emva kokufikisa. Ngelo xesha, ama-ovari (amadlala enza iiseli zamaqanda) aqala ukwenza i-AMH. Ngakumbi iiseli zamaqanda ezikhoyo, inqanaba eliphezulu le-AMH.
Kwabasetyhini, amanqanaba e-AMH anokubonelela ngolwazi malunga nokuzala, ukukwazi ukukhulelwa. Uvavanyo lungasetyenziselwa ukunceda ekuchongeni ukuphazamiseka ekuhambeni kwexesha okanye ukubeka esweni impilo yabasetyhini abaneentlobo ezithile zomhlaza we-ovari.
Amanye amagama: Uvavanyo lwehomoni ye-AMH, i-müllerian-inhibiting hormone, MIH, müllerian inhibiting factor, MIF, müllerian-inhibiting drug, MIS
Isetyenziselwa ntoni?
Uvavanyo lwe-AMH luhlala lusetyenziselwa ukujonga amandla omfazi wokuvelisa amaqanda anokuchunyiselwa ukukhulelwa. Amaqanda esetyhini angenza amawaka amaqanda ngexesha lokuzala kwakhe. Inani liyancipha njengoko umfazi esiya esiba mdala. Amanqanaba e-AMH anceda ukubonisa ukuba zingaphi iiseli zeqanda ezinokubakho. Oku kwaziwa njengendawo yokugcina ii-ovari.
Ukuba indawo yogcino-maqanda yamabhinqa iphezulu, unokuba nethuba elingcono lokukhulelwa. Unokuphinda alinde iinyanga okanye iminyaka ngaphambi kokuzama ukukhulelwa. Ukuba indawo yokugcina ii-ovari isezantsi, oko kunokuthetha ukuba owasetyhini uya kuba nengxaki yokukhulelwa, kwaye akufuneki alibazise ixesha elide ngaphambi kokuzama ukuba nomntwana.
Uvavanyo lwe-AMH lunokusetyenziselwa:
- Qikelela ukuqala kokuyeka ukuya exesheni, ixesha kubomi bomfazi xa amaxesha akhe okuya exesheni eyekile kwaye akakwazi ukuphinda akhulelwe. Ihlala iqala xa owasetyhini emalunga neminyaka engama-50 ubudala.
- Fumanisa isizathu sokuyeka ukuya exesheni kwangoko
- Nceda ufumane isizathu sokuba amenorrhea, ukunqongophala sexesheni. Ihlala ifunyaniswa kumantombazana angakhange aqale ukuya exesheni eneminyaka eyi-15 nakwabasetyhini abaphose amaxesha aliqela.
- Uncedo lokufumanisa isifo se-ovary syndrome (i-PCOS), isifo sehomoni esona sizathu siqhelekileyo sokuzala kwabasetyhini, ukungakwazi ukukhulelwa
- Jonga iintsana ezinezitho zangasese ezingachazwanga ngokucacileyo ukuba yindoda okanye ibhinqa
- Ukubeka iliso kwabasetyhini abaneentlobo ezithile zomhlaza we-ovari
Kutheni ndifuna uvavanyo lwe-AMH?
Unokufuna uvavanyo lwe-AMH ukuba ungumfazi onobunzima bokukhulelwa. Uvavanyo lunokunceda ukubonisa ukuba amathuba akho okuba ukhulelwe umntwana. Ukuba sele ubona ingcali yenzala, ugqirha wakho unokusebenzisa uvavanyo ukuxela kwangaphambili ukuba uza kuphendula kakuhle kunyango, njenge-vitro fertilization (IVF).
Amanqanaba aphezulu anokuthetha ukuba unokuba namaqanda amaninzi kwaye uya kuphendula ngcono kunyango. Amanqanaba asezantsi e-AMH athetha ukuba unokuba namaqanda ambalwa kwaye awunakuphendula kakuhle kunyango.
Unokufuna uvavanyo lwe-AMH ukuba ungumfazi onempawu ze-polycystic ovary syndrome (i-PCOS). Oku kubandakanya:
- Ukuphazamiseka kokuya exesheni, kubandakanya ukuya exesheni okanye i-amenorrhea
- Amabala
- Ukukhula okungaphezulu komzimba kunye nobuso
- Ukunciphisa ubungakanani besifuba
- Ukutyeba kwakho
Ukongeza, unokufuna uvavanyo lwe-AMH ukuba unyangwa umhlaza we-ovari. Uvavanyo lunokunceda ukubonisa ukuba unyango lwakho luyasebenza.
Yintoni eyenzekayo ngexesha lovavanyo lwe-AMH?
Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.
Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-AMH.
Ngaba bukhona ubungozi kuvavanyo?
Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.
Zithetha ntoni iziphumo?
Ukuba ungumfazi ozama ukukhulelwa, iziphumo zakho zinokukunceda ubonise ukuba ngawaphi amathuba akho okuba ukhulelwe. Inokukunceda ukuba uthathe isigqibo sokuba uzama nini ukukhulelwa. Inqanaba eliphezulu le-AMH linokuthetha ukuba amathuba akho angcono kwaye unokufumana ixesha elininzi ngaphambi kokuzama ukukhulelwa.
Inqanaba eliphezulu le-AMH linokuthetha ukuba une-polycystic ovary syndrome (i-PCOS). Akukho lunyango lwe-PCOS, kodwa iimpawu zinokulawulwa ngamayeza kunye / okanye notshintsho kwindlela yokuphila, njengokugcina ukutya okunempilo kunye nokuthambisa okanye ukutsheva ukususa iinwele zomzimba ezigqithileyo.
Inqanaba eliphantsi linokuthetha ukuba unokuba nengxaki yokukhulelwa. Ikwanokuthetha ukuba uqala ukuya exesheni. Inqanaba eliphantsi le-AMH liqhelekileyo kumantombazana amancinci nakwabasetyhini emva kokuyeka ukuya exesheni.
Ukuba unyangwa umhlaza we-ovari, uvavanyo lwakho lunokubonisa ukuba ngaba unyango lwakho luyasebenza.
Kwintsana eyindoda, inqanaba eliphantsi le-AMH linokuthetha ingxaki yemfuza kunye / okanye yehomoni ebangela amalungu esini angacacanga ukuba angamadoda okanye abhinqileyo. Ukuba amanqanaba e-AMH aqhelekileyo, oko kunokuthetha ukuba umntwana unamatyhalarha asebenzayo, kodwa awekho kwindawo efanelekileyo. Le meko inokunyangwa ngoqhaqho kunye / okanye unyango lwehomoni.
Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.
Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.
Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-AMH?
Ukuba ungumfazi uphathwa ngenxa yeengxaki zokuzala, uya kufumana ezinye iimvavanyo, kunye ne-AMH. Oku kubandakanya uvavanyo lwe-estradiol kunye ne-FSH, iihomoni ezimbini ezichaphazelekayo ekuzaleni kwakhona.
Izalathiso
- UCarmina E, uFruzzetti F, uLobo RA. Ukonyusa amanqanaba e-anti-Mullerian hormone kunye nobungakanani be-ovari kwiqela elincinci labasetyhini abane-hypothalamic amenorrhea: ukuchongwa ngakumbi kwekhonkco phakathi kwesifo se-polycystic ovary syndrome kunye ne-hypothalamic amenorrhea. NdinguJ Obstet Gynecol [kwi-Intanethi]. I-2016 Jun [icatshulwe nge-2018 kaDisemba 11]; 214 (6): 714.e1–714.e6. Ifumaneka kwi: https://www.ncbi.nlm.nih.gov/pubmed/26767792
- Iziko leyeza lokuZala [kwi-Intanethi]. IHouston: InfertilityTexas.com; c2018. Uvavanyo lwe-AMH; [icatshulwe nge-2018 kaDisemba 11]; [malunga nezikrini ezi-4]. Ifumaneka kwi: https://www.infertilitytexas.com/amh-testing
- UGrynnerup AG, uLindhard A, uSørensen S. Indima ye-anti-Müllerian hormone kwinzala yabasetyhini kunye nokuzala-ukujonga ngokubanzi. I-Acta Obstet Scand [i-Intanethi]. 2012 Nov [ikhankanywe ngo-2018 Dec 11]; 91 (11): 1252-60. Ifumaneka kwi: https://www.ncbi.nlm.nih.gov/pubmed/22646322
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- Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2018. Ukuyeka ukuya exesheni; [ihlaziywe ngo-2018 ngoMeyi 30; kucatshulwe ngo-2018 Dec 11]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/conditions/menopause
- Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2018. IPolycystic Ovary Syndrome; [ihlaziywe ngo-2018 Oktobha 18; kucatshulwe ngo-2018 Dec 11; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/conditions/polycystic-ovary-syndrome
- Ikliniki yaseMayo [kwi-Intanethi]. Isiseko seMayo seMfundo yezoNyango noPhando; c1998–2018. Amenorrhea: Iimpawu kunye noonobangela; 2018 Epreli 26 [icatshulwe ngowama-2018 kuDisemba 11]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.mayoclinic.org/diseases-conditions/amenorrhea/symptoms-causes/syc-20369299
- Ikliniki yaseMayo [kwi-Intanethi]. Isiseko seMayo seMfundo yezoNyango noPhando; c1998–2018. In vitro fertilization (IVF): Malunga; 2018 Mar 22 [icatshulwe ngowama-2018 kuDisemba 11]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.mayoclinic.org/tests-procedures/in-vitro-fertilization/about/pac-20384716
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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.