I-Esophagus kaBarrett

Umxholo

• Yintoni ebangela umqala kaBarrett
• Ziziphi izinto ezinobungozi?
• Ukuqaphela iimpawu ze-Barrett's esophagus
• Ukuchonga kunye nokuhlela i-esophagus yeBarrett
• Izinketho zonyango lwe-Barrett's esophagus
• Hayi okanye i-dysplasia ekumgangatho ophantsi
• Inkxaso mali yeNissen
• I-LINX
• Inkqubo yeStretta
• Ibanga eliphezulu le-dysplasia
• Ukupheliswa kwemitha rhoqo
• ICryotherapy
• Unyango lwe-Photodynamic
• Iingxaki
• Iyintoni imbonakalo yesifo sikaBarrett?

Yintoni i-esophagus kaBarrett

Umqala kaBarrett yimeko apho iiseli ezenza umqala wakho ziqala ukubonakala njengeeseli ezenza amathumbu akho. Oku kuhlala kusenzeka xa iiseli zonakaliswe kukuvezwa yiasidi esiswini.

Le meko ihlala ikhula emva kweminyaka yokufumana i-reflux yegastroesophageal (GERD). Kwezinye iimeko, isisu sikaBarrett sinokukhula sibe ngumhlaza wokuxhaxha.

Yintoni ebangela umqala kaBarrett

Owona nobangela wesisu sikaBarrett awukaziwa. Nangona kunjalo, imeko ihlala ibonwa kubantu abane-GERD.

I-GERD yenzeka xa izihlunu ezisezantsi komqala zingasebenzi kakuhle. Imisipha ebuthathaka ayizukuthintela ukutya kunye neasidi ekubuyeni kwakhona kwi-esophagus.

Kukholelwa ukuba iiseli kwi-esophagus zinokungaqhelekanga ngokuvezwa kwexesha elide kwisisu esiswini. I-Barrett's esophagus inokukhula ngaphandle kwe-GERD, kodwa abaguli abane-GERD banamaxesha ama-3 ukuya kwama-5 amathuba okuphuhlisa umqala kaBarrett.

Ngokumalunga neepesenti ezi-5 ukuya kwezi-10 zabantu abane-GERD bahlakulela i-esophagus kaBarrett. Ichaphazela amadoda phantse kabini ngokufuthi kunabafazi kwaye ihlala ifunyaniswa ineminyaka engama-55.

Ngexesha elingaphezulu, iiseli zelining esophageal lining zinokukhula zibe ziiseli ezichaphazelayo. Ezi seli zinokuthi emva koko zitshintshe zibe ziiseli ezinomhlaza. Nangona kunjalo, ukuba nomqala kaBarrett akuthethi ukuba uza kufumana umhlaza.

Kuqikelelwa ukuba kuphela malunga neepesenti ezi-0.5 zabantu abane-Barrett's esophagus abanomhlaza.

Ziziphi izinto ezinobungozi?

Ukuba uneempawu zeGERD ixesha elingaphezulu kweminyaka eli-10, unobungozi obandayo bokukhula komqala kaBarrett.

Eminye imingcipheko yokuphuhlisa umqala kaBarrett ubandakanya:

• ukuba yindoda
• ukuba yiCaucasian
• ungaphezulu kweminyaka engama-50
• ukuba noH pylori gastritis
• ukutshaya
• ukutyeba kakhulu

Izinto ezenza mandundu i-GERD zinokuwenza mandundu umqala kaBarrett. Oku kubandakanya:

• ukutshaya
• utywala
• Ukusetyenziswa rhoqo kwe-NSAIDS okanye i-Aspirin
• ukutya izixa ezikhulu ekutyeni
• ukutya okunamafutha amaninzi
• ukutya okuneziqholo
• ukulala okanye ukulala phantsi kweeyure ezine emva kokutya

Ukuqaphela iimpawu ze-Barrett's esophagus

Umqala kaBarrett awunampawu. Nangona kunjalo, ngenxa yokuba uninzi lwabantu olunale meko lukwanayo ne-GERD, baya kuhlala benesifo sentliziyo rhoqo.

Biza ugqirha wakho ngoko nangoko ukuba kukho ezi mpawu zilandelayo:

• ukuba nentlungu esifubeni
• ukugabha igazi, okanye ukugabha okufana nekofu
• ukuba nobunzima bokuginya
• ukudlula mnyama, ukulinda, okanye ilindle eligazi

Ukuchonga kunye nokuhlela i-esophagus yeBarrett

Ukuba ugqirha wakho ukrokrela ukuba une-esophagus ka-Barrett banoku-odola i-endoscopy. I-endoscopy yinkqubo esebenzisa i-endoscope, okanye ityhubhu enekhamera encinci kunye nokukhanya kuyo. I-endoscope ivumela ugqirha wakho ukuba abone ngaphakathi kwe-esophagus yakho.

Ugqirha wakho uya kujonga ukuze aqiniseke ukuba umqala wakho ubonakala upinki kwaye ukhazimla. Abantu abane-Barrett's esophagus bahlala benesifo somzimba esibonakala sibomvu kwaye sivelivethi.

Ugqirha wakho unokuthatha isampulu yethishu eya kubavumela ukuba baqonde ukuba loluphi utshintsho olwenzekayo kwindawo yakho.Ugqirha wakho uya kuvavanya isampulu yethishu yedysplasia, okanye ukukhula kweeseli ezingaqhelekanga. Isampuli yethishu ibekwa ngokusekwe kula madigri alandelayo otshintsho:

• akukho dysplasia: akukho sisele sibonakalayo siqhelo
• Ibanga eliphantsi le-dysplasia: inani elincinci lokuchaphazeleka kweseli
• Ibanga eliphezulu le-dysplasia: isixa esikhulu seeseli ezingaqhelekanga kunye neeseli ezinokuba ngumhlaza

Izinketho zonyango lwe-Barrett's esophagus

Unyango lwe-Barrett's esophagus luxhomekeke kweliphi inqanaba le-dysplasia ugqirha wakho anquma ukuba unayo. Izinketho zingaquka:

Hayi okanye i-dysplasia ekumgangatho ophantsi

Ukuba awunayo okanye i-dysplasia ekumgangatho ophantsi, ugqirha wakho uya kuncoma unyango oluya kukunceda ulawule iimpawu zakho ze-GERD. Amayeza okunyanga i-GERD abandakanya i-H2-receptor antagonists kunye neproton pump inhibitors.

Unokuba ngumgqatswa wotyando olunokukunceda ulawule iimpawu zakho zeGERD. Kukho utyando ezimbini ezenziwa rhoqo kubantu abane-GERD, ezibandakanya:

Inkxaso mali yeNissen

Olu tyando luzama ukomeleza i-esophageal sphincter (LES) ngokusonga umphezulu wesisu sakho ngaphandle kwe-LES.

I-LINX

Kule nkqubo, ugqirha wakho uya kufaka isixhobo se-LINX ejikeleze umqala ongezantsi. Isixhobo se-LINX senziwe ngamaso amancinci esinyithi asebenzisa umtsalane wemagnethi ukugcina imixholo yesisu sakho ingangeni kwi-esophagus yakho.

Inkqubo yeStretta

Ugqirha wenza inkqubo ye-Stretta nge-endoscope. Amaza erediyo asetyenziselwa ukwenza utshintsho kwimisipha yomqala kufutshane nalapho ujoyina isisu. Obu buchule bomeleza izihlunu kunye nokunciphisa ukubuyela kwesiqulatho sesisu.

Ibanga eliphezulu le-dysplasia

Ugqirha wakho unokucebisa ngakumbi ngenkqubo yokungena ukuba une-dysplasia ekumgangatho ophezulu. Umzekelo, ukususa iindawo ezonakeleyo zomqala ngokusetyenziswa kwe-endoscopy. Kwezinye iimeko, zonke iinxalenye zesifo zisuswe. Olunye unyango lubandakanya:

Ukupheliswa kwemitha rhoqo

Le nkqubo isebenzisa i-endoscope ene-attachment ekhethekileyo ekhupha ubushushu. Ubushushu bubulala iiseli ezingaqhelekanga.

ICryotherapy

Kule nkqubo, i-endoscope isasaza igesi ebandayo okanye ulwelo olufriza iiseli ezingaqhelekanga. Iiseli zivunyelwe ukuba zinyibilike, emva koko ziphinde zibe ngumkhenkce. Le nkqubo iphindaphindwa de zife iiseli.

Unyango lwe-Photodynamic

Ugqirha wakho uya kukujova ngekhemikhali ethe-ethe ekukhanyeni ebizwa ngokuba yi-porfimer (Photofrin). I-endoscopy iya kucwangciswa iiyure ezingama-24 ukuya kwezingama-72 emva kwenaliti. Ngexesha le-endoscopy, i-laser iyakwenza ukuba isebenze imichiza kwaye ibulale iiseli ezingaqhelekanga.

Iingxaki

Iingxaki ezinokubakho kuzo zonke ezi nkqubo zinokubandakanya iintlungu zesifuba, ukunciphisa isophagus, ukusika kwi-esophagus yakho, okanye ukuphuma komqala wakho.

Iyintoni imbonakalo yesifo sikaBarrett?

Isisu sikaBarrett sonyusa umngcipheko wokukhula komhlaza wokuqina. Nangona kunjalo, abantu abaninzi abanale meko abaze babe nomhlaza. Ukuba unayo i-GERD, thetha nogqirha wakho ukufumana isicwangciso sonyango esiza kukunceda ulawule iimpawu zakho.

Isicwangciso sakho sinokubandakanya ukwenza utshintsho kwindlela yokuphila njengokuyeka ukutshaya, ukunciphisa ukusela utywala, kunye nokuthintela ukutya okunezipayisi. Unokuqala ukutya ukutya okuncinci kumafutha agcweleyo, ulinde ubuncinci iiyure ezi-4 emva kokutya ukulala phantsi, nokuphakamisa intloko yebhedi yakho.

Onke la manyathelo aya kunciphisa i-reflux yegastroesophageal. Nawe unokumiselwa ngokuchasene ne-H2-receptor antagonists okanye iproton pump inhibitors.

Kwakhona kubalulekile ukucwangcisa ukuqeshwa rhoqo kunye nogqirha wakho ukuze bakwazi ukubeka iliso kwinqanaba lakho. Oku kuyakwenza ukuba kube lula ukuba ugqirha wakho afumane iiseli ezinomhlaza kwinqanaba lokuqala.