Yintoni ebangela ukungonelanga kwe-Exocrine Pancreatic?

Umxholo

• Yintoni i-EPI?
• Yintoni Ebangela EPI?
• Pancreatitis engapheliyo
• Pancreatitis ebukhali
• Ukuzimela ngokuzenzekelayo kwePancreatitis
• Seswekile
• Ugqirha
• Imiqathango yemfuza
• Isifo seCeliac
• Umhlaza wePancreatic
• Izifo zesisu ezivuthayo
• Isifo seZollinger-Ellison
• Ndingayikhusela kwi-EPI?

Yintoni i-EPI?

Iipancreas zidlala indima ebalulekileyo kwinkqubo yakho yokwetyisa. Umsebenzi wawo kukwenza kwaye kukhuphe ii-enzymes ezinceda inkqubo yakho yokwetyisa iphule ukutya kwaye ifunxe izakha mzimba. Ukungakwazi ukusebenza kwepancreatic pancreatic (EPI) kuyakhula xa iipancreas zakho zingazenzi okanye zingahambisi ngokwaneleyo kwezo enzymes. Ukunqongophala kwe-enzyme kwenza kube nzima kumzimba wakho ukuba uguqule ukutya kwiifom zokusebenzisa inkqubo yokugaya ukutya

Iimpawu ze-EPI ziye ziqapheleke xa ukuveliswa kwe-enzyme enoxanduva lokwaphula amathontsi amanqatha ukuya kwiipesenti ezi-5 ukuya kwezi-10 zesiqhelo. Xa oku kusenzeka unokulahleka kwesisindo, urhudo, isitulo esinamafutha kunye neoli, kunye neempawu ezinxulumene nokungondleki.

Yintoni Ebangela EPI?

I-EPI yenzeka xa iipancreas zakho ziyeka ukukhupha ii-enzymes ezaneleyo ukuxhasa ukwetyisa okuqhelekileyo.

Iimeko ezahlukeneyo zinokonakalisa i-pancreas yakho kwaye zikhokelele kwi-EPI. Ezinye zazo, ezinjenge-pancreatitis, zibangela i-EPI ngokonakalisa ngokuthe ngqo iiseli zepancreatic ezenza ii-enzymes zokwetyisa. Iimeko ezizuzwe njengeSshwachman-Diamond syndrome kunye necystic fibrosis nazo zinokubangela i-EPI, njengoko kunjalo nangepancreatic okanye uqhaqho esiswini.

Pancreatitis engapheliyo

I-pancreatitis engapheliyo kukudumba kwepancreas yakho engahambi ngokuhamba kwexesha. Olu hlobo lwepancreatitis sesona sizathu siphambili se-EPI kubantu abadala. Ukudumba okuqhubekayo kwepancreas konakalisa iiseli ezenza i-enzymes yokwetyisa. Kungenxa yoko le nto abantu abaninzi abane-pancreatitis eqhubekayo bekwakhula nokungoneliseki.

Pancreatitis ebukhali

Xa kuthelekiswa ne-pancreatitis engapheliyo, i-EPI ixhaphake kakhulu kwi-pancreatitis eza kwaye ihambe ixesha elifutshane. I-pancreatitis enganyangekiyo inokukhula ibe yifom engapheliyo ngokuhamba kwexesha, ukwandisa amathuba akho okuphuhlisa i-EPI.

Ukuzimela ngokuzenzekelayo kwePancreatitis

Olu luhlobo lwe-pancreatitis eqhubekayo eyenzekayo xa amajoni akho omzimba ehlasela i-pancreas. Unyango lwe-Steroid lunokunceda abantu abane-autoimmune pancreatitis babone imveliso ephuculweyo ye-enzyme.

Seswekile

Abantu abanesifo seswekile bahlala bene-EPI. Abaphandi abaluqondi ngokupheleleyo ubudlelwane phakathi kweswekile kunye ne-EPI. Kusenokwenzeka ukuba inxulumene nokungalingani kwamahomoni amava e-pancreas ngexesha leswekile.

Ugqirha

I-EPI sisiphumo esibi secala lokucola ukutya okanye utyando lwepancreas. Ngokwezifundo ezininzi zotyando lwesisu, ukuya kuthi ga kubantu abaye batyandwa iipancreas, isisu, okanye amathumbu amancinci aphezulu aya kuphuhlisa i-EPI.

Xa ugqirha esusa yonke into okanye inxenye yepancreas inokuvelisa isixa esincinci se-enzyme. Isisu, amathumbu, kunye nokuhlinzwa kwepancreatic kunokukhokelela kwi-EPI ngokutshintsha indlela inkqubo yakho yokwetyisa ehambelana ngayo. Umzekelo, ukususa inxenye yesisu kunokuphazamisa isisu esifanelekileyo sokudibanisa ngokupheleleyo izakhamzimba kunye nee-enzyme zepancreatic.

Imiqathango yemfuza

ICystic fibrosis sisifo esizuzwe njengelifa esibangela ukuba umzimba wenze umaleko ongqindilili wencindi. I-mucus ibambelela emiphungeni, kwinkqubo yokwetyisa nakwamanye amalungu. Phantse iipesenti ezingama-90 zabantu abane-cystic fibrosis bahlakulela i-EPI.

I-Shwachman-Diamond syndrome yinto enqabileyo kakhulu, eyifa elichaphazela amathambo akho, umongo wethambo kunye ne-pancreas. Abantu abanale meko bahlala bene-EPI ebuntwaneni. Umsebenzi wepancreatic uphucula malunga nesiqingatha sabantwana njengoko bekhula.

Isifo seCeliac

Isifo seCeliac sinxulunyaniswa nokungakwazi ukwetyisa i-gluten. Esi sifo sichaphazela abantu abadala baseMelika. Ngamanye amaxesha, abantu abalandela ukutya okungahambisani ne-gluten basenempawu, njengorhudo oluqhubekayo. Kule meko, iimpawu zingabangelwa yi-EPI ehambelana nesifo seCeliac.

Umhlaza wePancreatic

I-EPI yingxaki yomhlaza wepancreatic. Inkqubo yeseli yomhlaza ethatha indawo yeeseli zepancreatic inokukhokelela kwi-EPI, kwaye ithumba inokuthintela ii-enzymes ekungeneni kwendlela yokugaya ukutya. I-EPI ikwayingxaki yoqhaqho ukunyanga umhlaza wepancreatic.

Izifo zesisu ezivuthayo

Isifo sikaCrohn kunye ne-ulcerative colitis zombini zizifo zesisu ezivuthayo ezibangela ukuba amajoni akho omzimba ahlasele kwaye atshise umgudu wokugaya ukutya. Abantu abaninzi abanesifo sikaCrohn okanye i-ulcerative colitis banokuphuhlisa i-EPI. Nangona kunjalo, abaphandi abachazanga esona sizathu sobu budlelwane.

Isifo seZollinger-Ellison

Esi sisifo esinqabileyo apho amathumba kwi-pancreas yakho okanye kwenye indawo emathunjini akho enza izixa ezikhulu zehomoni ezikhokelela kwisisu esigqithisileyo. Esi sisu seasidi sigcina ii-enzymes zakho zokugaya ukutya zingasebenzi kakuhle, zikhokelela kwi-EPI.

Ndingayikhusela kwi-EPI?

Uninzi lweemeko ezinxulumene ne-EPI, kubandakanya umhlaza wepancreatic, i-cystic fibrosis, isifo seswekile, kunye nomhlaza wepancreatic, awunakulawulwa.

Kodwa kukho izinto ezithile onokuzilawula. Ukusetyenziswa kotywala ngamandla, ngoyena nobangela uqhelekileyo wokuphazamiseka kwepancreatitis. Ukudibanisa ukusetyenziswa kotywala kunye nokutya okunamafutha aphezulu kunye nokutshaya kunokwandisa amathuba akho okuba ne-pancreatitis. Abantu abane-pancreatitis ebangelwa kukusetyenziswa kotywala kakhulu bathambekele ekubeni nesifo esibuhlungu esiswini kunye nokuphuhlisa i-EPI ngokukhawuleza.

I-cystic fibrosis okanye i-pancreatitis esebenzayo kusapho lwakho ikwonyusa amathuba akho okuba ne-EPI.