I-CCSVI: Iimpawu, unyango, kunye nobudlelwane bayo kwi-MS

Umxholo

• Yintoni iCCSVI?
• Iimpawu zeCCSVI
• Oonobangela beCCSVI
• Ukuchonga iCCSVI
• Unyango lweCCSVI
• Umngcipheko wonyango wenkululeko
• Ikhonkco leCCSVI kunye neMS
• Uphando olongezelelekileyo lweCCSVI
• Yise kude

Yintoni iCCSVI?

Ukungabikho ngokwaneleyo kwe-cerebrospinal venous insufficiency (CCSVI) kubhekisa ekunciphiseni kwemithambo entanyeni. Le meko ichazwe ngokungacacanga inomdla kubantu abane-MS.

Inzala ibangelwa sisindululo esiphikisayo sokuba i-CCSVI ibangele i-MS, kunye nokuba utyando lwe-transAMcular autonomic modulation (TVAM) kwimithambo yegazi entanyeni inokunciphisa i-MS.

Uphando olunzulu lufumene ukuba le meko ayihambelani ne-MS.

Ngapha koko, olu tyando alunoncedo. Isenokubangela iingxaki ezisongela ubomi.

Ukhuphe isilumkiso malunga neTVAM kwaye uthintele inkqubo. Ayigunyaziswanga e-United States njengonyango lweCCSVI okanye lwe-MS.

I-FDA iphumeze inkqubo yokuxela nakuphi na ukungathobeli okanye iingxaki ezinxulumene nonyango.

Kukho inkolelo yokuba ukungonelanga kwegazi le-venous kunganxulunyaniswa nokunciphisa imithambo entanyeni. Kucetyisiwe ukuba ukuncipha kunokubangela ukunciphisa ukuhamba kwegazi kwingqondo nakumnqonqo.

Ngenxa yoko, abo bakhuthaza ingxoxo yeCCSVI-MS ephikisayo bacebisa ukuba igazi libuyela umva kwingqondo nakumqolo, kubangela uxinzelelo kunye nokudumba.

Ithiyori enye yeCCSVI kukuba imeko ibangela ukhuphelo loxinzelelo okanye ukunciphisa ukuphuma kwegazi kushiya inkqubo ye-nervous system (CNS).

Iimpawu zeCCSVI

I-CCSVI ayichazwanga kakuhle ngokweendlela zokuhamba kwegazi, kwaye ayihambelani naziphi na iimpawu zeklinikhi.

Oonobangela beCCSVI

Isizathu ngqo kunye nenkcazo yeCCSVI ayimiselwanga. Umzekelo, inani elichanekileyo lokuhamba kwemithambo ye-cerebrospinal enokuthi ithathelwe ingqalelo njengeqhelekileyo okanye efanelekileyo ayisiyiyo imilinganiselo yempilo.

Ngaphantsi komndilili we-cerebrospinal flow venous flow kukholelwa ekubeni yinto yokuzalwa (ekhoyo ekuzalweni) kwaye ayikhokeleli kuyo nayiphi na imiba yezempilo.

Ukuchonga iCCSVI

Ukuchonga iCCSVI kunokuncedwa kuvavanyo lokucinga. I-ultrasound isebenzisa amaza esandi esihamba ngesantya esiphezulu ukwenza umfanekiso wolwelo ngaphakathi komzimba wakho.

Ugqirha wakho unokusebenzisa i-ultrasound okanye i-magnetic resonance venography ukujonga imithambo entanyeni yakho kwaye ujonge nayiphi na imiba engalunganga yolwakhiwo, kodwa akukho migangatho apho ukungalingani okwaneleyo okanye umsele ulinganiswa khona.

Olu vavanyo alwenziwa kubantu abane-MS.

Unyango lweCCSVI

Olona nyango lucetywayo lweCCSVI yiTVAM, utyando lwe-angioplasty ene-venous, ekwabizwa ngokuba lonyango lwenkululeko. Yenzelwe ukuvula imithambo emxinwa. Ugqirha ufaka ibhaluni encinci emithanjeni ukuyandisa.

Le nkqubo ichazwe njengendlela yokususa ukubhloka kunye nokunyusa ukuhamba kwegazi kwingqondo nakwintambo yomqolo.

Nangona abanye abantu ababenenkqubo kwisimo sokulinga baxela ukuphucuka kwemeko yabo, uninzi lwalunamaxwebhu e-restenosis kuvavanyo lwabo lokucinga, oko kuthetha ukuba imithambo yegazi inciphile kwakhona.

Ukongeza, akucaci nokuba abo baxele ukuphuculwa kweklinikhi banalo naluphi na utshintsho olunxulumene nokuhamba kwegazi.

Uphando oluphanda ngokusebenza kotyando lweCCSVI aluthembisi.

Ngokwe-MS Society, uphononongo lolingo lweklinikhi lwango-2017 lwabantu abali-100 abane-MS bafumanisa ukuba i-angioplasty ye-venous ayikhange izinciphise iimpawu zabathathi-nxaxheba.

Umngcipheko wonyango wenkululeko

Ngenxa yokuba unyango lweCCSVI alungqiniswanga lusebenza, oogqirha bacebisa kakhulu ngokuchasene notyando ngenxa yomngcipheko weengxaki ezinzulu. Ezi ngxaki zibandakanya:

• amahlwili egazi
• ukubetha kwentliziyo okungaqhelekanga
• ukwahlulwa komthambo
• usulelo
• ukuqhekeka kwemithambo

Ikhonkco leCCSVI kunye neMS

Ngo-2008, uGqirha Paolo Zamboni wase-University of Ferrara e-Itali wazisa ikhonkco elicetywayo phakathi kwe-CCSVI ne-MS.

UZamboni wenze isifundo ngabantu abane-MS nangaphandle kwe-MS. Usebenzisa imaging ye-ultrasound, uthelekise imithambo yegazi kuwo omabini amaqela abathathi-nxaxheba.

Uxele ukuba iqela lokufunda eline-MS lalinokuhamba kwegazi okungaqhelekanga ukusuka kwingqondo nakumqolo, ngelixa iqela lokufunda ngaphandle kwe-MS lalinokuhamba kwegazi okuqhelekileyo.

Ngokusekwe kwiziphumo zakhe, uZamboni wagqiba kwelokuba i-CCSVI yayingunobangela we-MS.

Olu nxibelelwano, nangona kunjalo, ekuqaleni lwalungumcimbi wengxoxo kwindawo yezonyango. Kususela oko kungavunyelwanga kwaye, ngokusekwe kuphando lweqela lakhe, uZamboni ngokwakhe uthe unyango lonyango alukhuselekanga okanye alusebenzi.

Ngapha koko, umzimba okhulayo wobungqina ucebisa ukuba i-CCSVI ayinxibelelananga ngqo ne-MS.

Abaphandi bacacisa ukuba ukungangqinelani kwiziphumo kunokubangelwa ziimeko ezahlukeneyo, kubandakanya ukungangqinelani kwiindlela zokucinga, ukuqeqeshwa kwabasebenzi, kunye nokutolikwa kweziphumo.

Uphando olongezelelekileyo lweCCSVI

Isifundo sikaZamboni yayingekuphela kwesifundo esasenziwe kumzamo wokufumana ikhonkco phakathi kweCCSVI neMS.

Ngo-2010, uMbutho weSizwe we-MS e-United States kunye ne-MS Society yase-Canada bazibandakanya kwaye bagqiba izifundo ezisixhenxe ezifanayo. Kodwa iiyantlukwano ezinkulu kwiziphumo zazo khange zikhombe kumanyano phakathi kweCCSVI kunye neMS, ekhokelela kubaphandi ukuba bagqibe ukuba akukho khonkco.

Olunye uphononongo eneneni lwalunokonyuka okukhulu kumaxabiso okubuyela umva kwe-MS ngenxa yenkqubo, ekhokelele kwizifundo eziphela kwangoko.

Ngapha koko, abanye abathathi-nxaxheba bafa ngenxa yesilingo, ngelo xesha esasibandakanya ukubeka i-stent emthanjeni.

Yise kude

I-MS ayinakulindeleka ngamanye amaxesha, ke kuyaqondakala ukufuna isiqabu kunye nonyango olusebenzayo. Kodwa abukho ubungqina bokuqinisekisa ukuba ukunyanga iCCSVI kuya kuyiphucula i-MS okanye kumise ukuqhubela phambili kwayo.

“Unyango lwenkululeko” lusinika ithemba elilahlekileyo lokunyanga ngokungummangaliso kwisifo esibuhlungu ngexesha apho sinokhetho lokwenene nolunentsingiselo.

Oku kunokuba yingozi, njengoko singenazo iindlela ezilungileyo zokulungisa okanye ukubuyisela i-myelin ilahlekile ngelixa ulibazisa unyango.

Ukuba unyango lwakho lwangoku alulawuli kakuhle i-MS yakho, unganqikazi ukufikelela kugqirha wakho. Bangasebenza nawe ukufumana unyango olusebenzayo.