ICetuximab (i-Erbitux)

Umxholo

• Iimpawu
• Kusetyenziswa kwanjani
• Imiphumela
• Ukungqinelana

I-Erbitux yi-antineoplastic yokusetyenziswa ngenaliti, enceda ukumisa ukukhula kweeseli zomhlaza. Eli yeza linokusetyenziswa kuphela njengokuyalelwa ngugqirha kwaye lisetyenziselwa kuphela esibhedlele.

Ngokwesiqhelo, eli yeza lisetyenziswa emthanjeni ngumongikazi kube kanye ngeveki ukulawula ukukhula komhlaza.

Iimpawu

La mayeza ayacetyiswa ukuba anyangwe umhlaza wekolon, umhlaza womqala, umhlaza wentloko kunye nomhlaza wentamo.

Kusetyenziswa kwanjani

I-Erbitux isetyenziswe ngenaliti emthanjeni olawulwa ngumongikazi esibhedlele. Ngokubanzi, ukulawula ukukhula kwethumba, isetyenziswa kube kanye ngeveki, kwimeko ezininzi idosi yokuqala yi-400 mg ye-cetuximab nge-m² yomhlaba kunye nawo onke amathamo eveki nganye angama-250 mg we-cetuximab nge-m² nganye.

Ukongeza, ukujonga ngononophelo kuyafuneka ngexesha lonke lolawulo lwamayeza ukuya kuthi ga kwiyure eli-1 emva kokufakwa kwesicelo. Ngaphambi kokufakwa, amanye amayeza anje nge-antihistamines kunye ne-corticosteroid kufuneka anikwe ubuncinci iyure enye ngaphambi kolawulo lwe-cetuximab.

Imiphumela

Ezinye iziphumo zokusebenzisa eli yeza zibandakanya ukuqunjelwa, iintlungu zesisu, ukungabi namdla wokutya, ukuqhina, ukugaya ukutya okungalunganga, ubunzima bokuginya, i-mucositis, isicaphucaphu, ukudumba emlonyeni, ukugabha, umlomo owomileyo, i-anemia, ukwehla kweeseli ezimhlophe zegazi, ukomisa, ukunciphisa umzimba umqolo obuhlungu, ukudumba komzimba, ukulahleka kweenwele, irhashalala, iingxaki zesikhonkwane, ukurhawuzelela, ukuqaqanjelwa sisikhumba, ukukhohlela, ukuphefumla kancinci, ukuba buthathaka, ukudakumba, umkhuhlane, intloko ebuhlungu, ukuqaqanjelwa sisisu, ukugodola, usulelo kunye nentlungu.

Ukungqinelana

Ukusetyenziswa kwale iyeza contraindicated xa ukhulelwe, ngexesha lokuncancisa kunye hypersensitivity kuwo nawaphi na amacandelo ichiza.