Tofacitinib Citrate
Umxholo
I-Tofacitinib Citrate, ekwabizwa ngokuba yi-Xeljanz, sisiyobisi sokunyanga isifo samathambo, esivumela ukukhululeka kwentlungu nokudumba kumalungu.
Eli ziko lisebenza ngaphakathi kwiiseli, kuthintela ukusebenza kwee-enzymes ezithile, i-JAK kinases, ethintela ukuveliswa kwee-cytokines ezithile. Olu thintelo lunciphisa ukuphendula ngokudumba kwamajoni omzimba, ngaloo ndlela kuncitshiswe ukudumba kwamalungu.
Iimpawu
I-Tofacitinib Citrate ibonakalisiwe kunyango lwe-rheumatoid arthritis esebenzayo, kwizigulana zabantu abadala ezingaphendulanga kolunye unyango.
Indlela yokuthatha
Kufuneka uthathe ithebhulethi enye yeTofacitinib Citrate amaxesha ama-2 ngosuku, anokuthathwa yedwa okanye ngokudibanisa namanye amayeza e-rheumatoid arthritis, njenge-methotrexate, umzekelo.
Iipilisi zeTofacitinib zeCitrate kufuneka ziginywe ziphelele, ngaphandle kokophula okanye ukuhlafuna kunye neglasi yamanzi.
Imiphumela
Ezinye zeziphumo ebezingalindelekanga zeTofacitinib Citrate zinokubandakanya ukusuleleka kwimpumlo nakwipharynx, inyumoniya, i-herpes zoster, i-bronchitis, umkhuhlane, i-sinusitis, usulelo lwe-urinary tract, usulelo lwe-pharynx, utshintsho kwiziphumo zovavanyo lwegazi kunye ne-enzyme zesibindi ezandisiweyo, ukuzuza ubunzima, iintlungu zesisu , ukugabha, isifo sesisu, urhudo, isicaphucaphu, ukugaya ukutya okungaginyisi mathe, ukwanda kwamafutha egazi kunye nokutshintsha kwecholesterol, iintlungu kwezihlunu, imisipha okanye imisipha, iintlungu ezidibeneyo, ukubola kwegazi, umkhuhlane, ukudinwa kakhulu, ukudumba emiphethweni yomzimba, intloko ebuhlungu, ubunzima bokulala, uxinzelelo lwegazi oluphezulu, ukuphefumla kancinci, ukukhohlela okanye ukuhla kwesikhumba.
Ukungqinelana
I-Tofacitinib Citrate iyaphikiswa kubantwana nakwishumi elivisayo abangaphantsi kweminyaka eyi-18, abaguli abanesifo esibi sesibindi kunye nezigulana ezinokungezwani neTofacitinib Citrate okanye ezinye izinto zefomula.
Ukongeza, ayifanele isetyenziswe ngabafazi abakhulelweyo okanye abancancisayo ngaphandle kwengcebiso kagqirha.