Yintoni ekufuneka uyazi malunga novavanyo lweklinikhi yeMantle Cell Lymphoma

Umxholo

• Yintoni ulingo lwezonyango?
• Uvavanyo luvavanywa njani ukhuseleko ngaphambi kovavanyo lweklinikhi?
• Zeziphi izibonelelo ezinokubakho zokuthatha inxaxheba kuvavanyo lweklinikhi?
• Zeziphi iingozi ezinokubakho zokuthatha inxaxheba kuvavanyo lweklinikhi?
• Ndingafunda phi ngezilingo zangoku nezizayo zeklinikhi?
• Yintoni endifanele ndiyibuze ugqirha wam ngaphambi kokujoyina uvavanyo lwezonyango?
• Ukuthatha

Kwiminyaka yakutshanje, unyango olutsha lwe-mantle cell lymphoma (MCL) luye lwanceda ukuphucula ixesha lokuphila kunye nomgangatho wobomi kubantu abaninzi abanesi sifo. Nangona kunjalo, i-MCL isajongwa ngokubanzi njengenganyangekiyo.

Kuphando lwabo oluqhubekayo lonyango, abaphandi kwihlabathi liphela bayaqhubeka nokuphuhlisa kunye nokuvavanya iindlela zonyango ezintsha ze-MCL.

Ukufikelela kolu vavanyo lonyango, iAmerican Cancer Society icebisa ukuba abantu abane-MCL banokufuna ukuthatha inxaxheba kuvavanyo lweklinikhi.

Funda ukuze ufunde ngakumbi malunga nezibonelelo ezinokubakho kunye nemingcipheko yokwenza oko.

Yintoni ulingo lwezonyango?

Uvavanyo lweklinikhi luhlobo lophando apho abathathi-nxaxheba bafumana unyango, ukusebenzisa isixhobo, okanye ukwenza uvavanyo okanye enye inkqubo efundwayo.

Abaphandi basebenzisa iimvavanyo zeklinikhi ukufunda ukuba amayeza amatsha kunye nezinye iindlela zonyango zikhuselekile kwaye ziyasebenza ekunyangeni izifo ezithile, kubandakanya iMLL. Basebenzisa ulingo lweklinikhi ukuthelekisa iindlela zonyango esele zikhona nezintsha zokufunda ezifanelekileyo kumaqela athile ezigulana.

Ngexesha lovavanyo lwezonyango kunyango lwe-MCL, abaphandi baqokelela ulwazi malunga neziphumo ebezingalindelekanga ezithathwa ngabathathi-nxaxheba ngexesha lonyango. Baqokelela ulwazi malunga neziphumo ezibonakalayo zonyango ekusindeni kwabathathi-nxaxheba, iimpawu, kunye nezinye iziphumo zempilo.

Ulawulo lokutya kunye neziyobisi (i-FDA) kuphela luvuma unyango olutsha emva kokuba lufunyenwe lukhuselekile kwaye lusebenza kwizilingo zeklinikhi.

Uvavanyo luvavanywa njani ukhuseleko ngaphambi kovavanyo lweklinikhi?

Phambi kokuba uvavanyo lomhlaza luvavanywe kuvavanyo lweklinikhi, ludlula kwizigaba ezininzi zokuvavanywa elebhu.

Ngexesha lokuvavanywa elebhu, izazinzulu zinokuvavanya unyango kwiiseli ezinomhlaza ezikhule kwiitya zepetri okanye kwiityhubhu zovavanyo. Ukuba iziphumo zolo vavanyo ziyathembisa, banokuvavanya unyango kwizilwanyana eziphilayo ezinjengeempuku zebhu.

Ukuba unyango lufunyenwe lukhuselekile kwaye lusebenza kwizifundo zezilwanyana, izazinzulu zinokuthi emva koko ziphuhlise inkqubo yolingo yeklinikhi yokuyifunda ebantwini.

Iphaneli yeengcali iphonononga umgaqo ngamnye wolingo lwezonyango ukunceda ukuqinisekisa ukuba isifundo siqhutywa ngendlela ekhuselekileyo nenokuziphatha.

Zeziphi izibonelelo ezinokubakho zokuthatha inxaxheba kuvavanyo lweklinikhi?

Ukuthatha inxaxheba kuvavanyo lweklinikhi kunokukunika ukufikelela kwindlela yonyango yovavanyo engagunyaziswanga okanye yenziwe yabakho ngokubanzi, njengale:

• uhlobo olutsha lwe-immunotherapy, unyango ekujoliswe kulo, okanye unyango lwemfuza
• isicwangciso esitsha sokusebenzisa unyango olukhoyo ngokwamanqanaba ahlukeneyo eMCL
• indlela entsha yokudibanisa unyango olukhoyo kunyango oludibeneyo

Akukho siqinisekiso sokuba indlela yonyango yokulinga iya kusebenza. Nangona kunjalo, inokukunika ukhetho lonyango xa unyango olusemgangathweni alufumaneki okanye lungakhange lusebenze kakuhle kuwe.

Ukuba uthatha isigqibo sokuthatha inxaxheba kuvavanyo lweklinikhi, uya kuthi uncede abaphandi bafunde ngakumbi nge-MCL. Oku kunokubanceda baphucule ukhetho kunyango lwezigulana kwixa elizayo.

Ngamanye amaxesha, kunokuba kufikeleleke ngakumbi kuwe ukuba ufumane unyango kuvavanyo lweklinikhi. Abaxhasi besifundo ngamanye amaxesha bagubungela ezinye okanye zonke iindleko zonyango lwabathathi-nxaxheba.

Zeziphi iingozi ezinokubakho zokuthatha inxaxheba kuvavanyo lweklinikhi?

Ukuba ufumana unyango kuvavanyo lwezonyango, kunokwenzeka ukuba unyango:

• ayinakusebenza kunye nonyango oluqhelekileyo
• ayinakusebenza ngcono kunonyango oluqhelekileyo
• kunokubangela iziphumo ebezingalindelekanga ezinokubakho

Kwezinye izilingo zeklinikhi, abaphandi bathelekisa unyango lokulinga kunye nonyango oluqhelekileyo. Ukuba ityala "limfanyekisiwe," abathathi-nxaxheba abazi ukuba loluphi unyango abalufumanayo. Unokufumana unyango oluqhelekileyo-kwaye kamva ufumanise ukuba unyango lokulinga lusebenza ngcono.

Ngamanye amaxesha, iimvavanyo zeklinikhi zithelekisa unyango lokulinga kunye ne-placebo. I-placebo lunyango olungabandakanyi izinto ezisebenzayo zokulwa umhlaza. Nangona kunjalo, ii-placebos kunqabile ukuba zisetyenziswe zodwa kuvavanyo lweklinikhi kumhlaza.

Ungakufumanisa kuphazamisana nokuthatha inxaxheba kuvavanyo lweklinikhi, ngakumbi ukuba kufuneka uye kudinga rhoqo okanye uhambe umgama omde ukuze ufumane unyango okanye uvavanyo.

Ndingafunda phi ngezilingo zangoku nezizayo zeklinikhi?

Ukufumana iimvavanyo zangoku kunye nezizayo zeklinikhi zabantu abane-MCL, kunokunceda:

• buza ugqirha wakho ukuba bayazi malunga naluphi na uvavanyo lwezonyango onokuthi ufaneleke kulo
• khangela iimvavanyo ezifanelekileyo zeklinikhi usebenzisa idathabheyisi eqhutywa yi-US National Library of Medicine, okanye CentreWatch
• jonga iiwebhusayithi zabenzi bamayeza ngolwazi malunga novavanyo lweklinikhi abazenzayo ngoku okanye abacwangcisela ikamva

Eminye imibutho ikwabonelela ngeenkonzo ezilinganayo zolingo ukunceda abantu bafumane izilingo ezihambelana neemfuno zabo kunye neemeko.

Yintoni endifanele ndiyibuze ugqirha wam ngaphambi kokujoyina uvavanyo lwezonyango?

Ngaphambi kokuba uthathe isigqibo sokuthatha inxaxheba kuvavanyo lweklinikhi, kuya kufuneka uthethe nogqirha wakho kunye namalungu eqela lophando lonyango ukuba ufunde malunga nezibonelelo ezinokubakho, umngcipheko kunye neendleko zokuthatha inxaxheba.

Nalu uluhlu lwemibuzo onokufumanisa iluncedo ukuyibuza:

• Ngaba ndiyazifezekisa iikhrayitheriya zolu vavanyo lweklinikhi?
• Ngaba abaphandi baya kusebenzisana neqela lam lonyango?
• Ngaba abaphandi baya kunika abathathi-nxaxheba indawo ye-placebo, unyango oluqhelekileyo, okanye unyango? Ndizokwazi ukuba loluphi unyango endilufumanayo?
• Yintoni esele isaziwa ngonyango olufundwayo kweli tyala?
• Zeziphi iziphumo ezinokubakho, iingozi, okanye izibonelelo zonyango?
• Zeziphi iimvavanyo ekuya kufuneka ndiyenze ngexesha lokuvavanywa?
• Ndihlala ndilufumana phi unyango kunye novavanyo?
• Ngaba kuya kufuneka ndibhatalele epokothweni indleko zonyango kunye neemvavanyo?
• Ngaba umboneleli wam weinshurensi okanye umxhasi wesifundo uya kuzihlawula iindleko?
• Ngubani endinokuqhagamshelana naye ukuba ndinemibuzo okanye izinto endixhalabisayo?
• Kwenzeka ntoni ukuba ndithatha isigqibo sokuba andisafuni ukuthatha inxaxheba?
• Isifundo sicwangciselwe ukuba siphele nini? Kuza kwenzeka ntoni xa isifundo siphela?

Ugqirha wakho unokukunceda ulinganise izibonelelo ezinokubakho kunye nomngcipheko wokuthatha inxaxheba kuvavanyo lweklinikhi. Banokukunceda uqonde ezinye iindlela zokhetho zonyango.

Ukuthatha

Ukuba ukhetho oluqhelekileyo lonyango alunakwenzeka ukuhlangabezana neemfuno zakho zonyango okanye iinjongo nge-MCL, ugqirha wakho unokukukhuthaza ukuba uthathe inxaxheba kuvavanyo lweklinikhi.

Ugqirha wakho unokukunceda uqonde izibonelelo ezinokubakho kunye nomngcipheko wokuthatha inxaxheba kuvavanyo lweklinikhi. Banokukunceda ufunde ngakumbi malunga nezinye iindlela zokhetho ukuba ugqiba ekubeni ungathathi nxaxheba kuvavanyo lweklinikhi okanye ukuba awulungelanga naluphi na uvavanyo lwezonyango.

Thetha nogqirha wakho ukuba ufunde ukuba ukuthatha inxaxheba kuvavanyo lweklinikhi kunokuba yinto elungileyo kuwe.