Yintoni iDAO? Ukucaciswa kweDiamine Oxidase Supplements

Umxholo

• Yintoni iDAO?
• Ukusilela kwe-DAO kunye nokunganyamezelani kweMbali
• Izibonelelo ezinokubakho zeZibonelelo zeDAO
• Iimpawu zokugaya
• Ukuhlaselwa kweMigraine kunye neentloko
• Isikhumba Rash
• Ayinyangi
• Unyango lweZondlo kwi-DAO
• Ukuphucula umsebenzi we-DAO
• Ukutya ekufuneka sikuphephe
• Amanyathelo okhuseleko kunye neengcebiso zedosi
• Umgca osezantsi

I-Diamine oxidase (i-DAO) yi-enzyme kunye nesongezelelo sesondlo esisetyenziselwa ukunyanga iimpawu zokunganyamezelani kwe-histamine.

Ukuxhasa i-DAO kunokuba nezibonelelo ezithile, kodwa uphando lilinganiselwe.

Eli nqaku liphonononga izongezo ze-DAO, kubandakanya izibonelelo zabo, idosi kunye nokhuseleko.

Yintoni iDAO?

I-Diamine oxidase (i-DAO) yi-enzyme yokwetyisa eveliswe kwizintso zakho, i-thymus, kunye nethumbu lamathumbu lendlela yokugaya ukutya.

Umsebenzi wawo ophambili kukwaphula i-histamine egqithisileyo emzimbeni wakho (1).

Imbali yindawo eyenzeka ngokwendalo enceda ukumisela imisebenzi ethile yokugaya ukutya, i-nervous, kunye ne-immune system.

Ukuba ukhe wakha waphendulwa, mhlawumbi uqhelene neempawu eziqhelekileyo ezinxulunyaniswa namanqanaba aphezulu e-histamine, njengokuxinana kwempumlo, ulusu olurhawuzayo, iintloko, kunye nokuthimla.

Unokufaka i-histamine ngokutya kwakho. Ngokwendalo kwenzeka ekutyeni okuthile-ngakumbi ezo sele zikhulile, ziphilisiwe, okanye zifakwe isonka samasi, iwayini, i-pickles kunye nenyama yokutshaya (1).

I-DAO igcina amanqanaba e-histamine kuluhlu olusempilweni ukuthintela ukungonwabi kweempawu ezibangelwa yi-histamine.

I-Diamine oxidase (i-DAO) yi-enzyme enceda ukwehlisa i-histamine emzimbeni wakho, oko ke kunciphisa iimpawu ezingathandekiyo, njengokuxinana kwempumlo, ulusu olurhawuzayo, intloko ebuhlungu kunye nokuthimla.

Ukusilela kwe-DAO kunye nokunganyamezelani kweMbali

Ukunganyamezelani kwembali yimeko yonyango eyenzeka ngenxa yenqanaba eliphezulu le-histamine.

Esinye sezizathu zokurhanela ukunganyamezelani kwe-histamine kukusilela kwe-DAO ().

Xa amanqanaba akho e-DAO ephantsi kakhulu, kunzima kumzimba wakho ukuba usebenze kakuhle kwaye ukhuphe i-histamine engaphezulu. Ngenxa yoko, amanqanaba e-histamine anyuka, ekhokelela kwiimpawu ezahlukeneyo zomzimba.

Iimpawu zokunganyamezelani kwe-histamine zihlala zifana nezo zempendulo. Ziyakwazi ukusuka kubumnene ukuya kubunzima kwaye zibandakanya ():

• ukuxinana kwempumlo
• intloko ebuhlungu
• ukurhawuzelela ulusu, irhashalala kunye nemingxunya
• Ukuthimla
• isifuba kunye nokuphefumla nzima
• ukubetha kwentliziyo ngokungaqhelekanga (arrhythmia)
• urhudo, isisu esibuhlungu, kunye noxinzelelo lokugaya ukutya
• isicaphucaphu nokugabha
• uxinzelelo lwegazi oluphantsi (hypotension)

Izinto ezahlukeneyo zinokuba negalelo ekunciphiseni umsebenzi we-DAO okanye ukuveliswa okungaphezulu kwe-histamine, kubandakanya utshintsho kwimfuza, ukusetyenziswa kotywala, amayeza athile, ukwanda kwebacteria yamathumbu, kunye nokutya ukutya okuninzi okune-histamine ().

Ukunganyamezelani kwembali kunokuba nzima ukuyixilonga, njengoko iimpawu zayo zinomdla kwaye ziyafana nezinye iimeko zonyango (1,).

Ke ngoko, ukuba ucinga ukuba ujamelana nokunganyamezelani kwe-histamine, nxibelelana nomboneleli wezempilo ofanelekileyo ukuba aphande ngononophelo oonobangela beempawu zakho ngaphambi kokuzama ukuzifumanisa okanye ukuzinyanga ngokwakho.

Ukunganyamezelani kwembali kunokukhula ngenxa yokunqongophala kwe-DAO kwaye kukhokelele kwiimpawu ezohlukeneyo ezingathandekiyo ezihlala zilinganisa impendulo.

Izibonelelo ezinokubakho zeZibonelelo zeDAO

Ukusilela kwe-DAO kunye nokunganyamezelani kwe-histamine kunganyangwa ngeendlela ezahlukeneyo, kubandakanya ukongeza nge-DAO.

Uphando lwakwangoko lubonisa ukuba izongezo ze-DAO zinokunciphisa iimpawu ezithile zokunganyamezelani kwe-histamine, kubandakanya iintloko, irhashalala kunye noxinzelelo lokugaya ukutya.

Iimpawu zokugaya

Kwisifundo seeveki ezi-2 kubantu abali-14 abane-histamine yokunganyamezelani kunye neempawu ezibandakanya iintlungu zesisu, ukudumba, okanye isifo sorhudo, i-93% yabathathi-nxaxheba baxele isisombululo seempawu zokugaya ubuncinci emva kokuthatha i-4.2 mg ye-DAO kabini yonke imihla ().

Ukuhlaselwa kweMigraine kunye neentloko

Isifundo senyanga e-1 kubantu abali-100 abanesiphene se-DAO ngaphambili safumanisa ukuba abathathi-nxaxheba abongeza yonke imihla nge-DAO bafumana ukuncipha nge-23% ngexesha lokuhlaselwa kwe-migraine, xa kuthelekiswa neqela le-placebo ().

Isikhumba Rash

Isifundo seentsuku ezingama-30 kubantu abangama-20 abane-urticaria engapheliyo (ukukhawuleza kwesikhumba) kunye nokusilela kwe-DAO kuqatshelwe ukuba abathathi-nxaxheba abafumana isongezelelo kabini ngemini bafumana ukukhululeka okukhulu kwiimpawu kwaye bafuna amayeza amancinci e-antihistamine ().

Nangona ezi zifundo zibonisa ukuba ukongeza kunye ne-DAO kunokuphelisa okanye kuphucule iimpawu zokusilela, akukho siqinisekiso sokuba sisebenza kuye wonke umntu.

Ekugqibeleni, uphando oluthe kratya luyafuneka ukufumana izigqibo ezichanekileyo.

Uphando lwakwangoko lubonisa ukuba izongezo ze-DAO zinokuphucula iimpawu ezithile ezinxulunyaniswa nokusilela kwe-DAO kunye nokunganyamezelani kwe-histamine, kubandakanya uhlaselo lwe-migraine, irhashalala lolusu kunye nemicimbi yokwetyisa. Okwangoku, kufuneka uphando olongezelelekileyo.

Ayinyangi

Ukuqonda kwezesayensi ukunganyamezelani kwe-histamine kunye nokusilela kwe-DAO kusekwinqanaba lokuqala.

Izinto ezahlukeneyo zinokuchaphazela ukuveliswa kwe-DAO kunye ne-histamine kwiindawo ezahlukeneyo zomzimba wakho. Ukuphendula ngonobangela wale micimbi akukho lula njengokutshintsha i-DAO ngesongezelelo (1,).

Umsebenzi we-DAO wongeza umsebenzi wokophula i-histamine engena emzimbeni wakho ngaphandle, njengokutya okanye iziselo.

Ukuthatha olu ncediso aluyi kuchaphazela amanqanaba e-histamine eveliswe ngaphakathi, njengoko olu hlobo lwe-histamine luye lwaphulwa yi-enzyme eyahlukileyo ebizwa ngokuba yi-N-methyltransferase ().

Nangona izongezo ze-DAO zinokunciphisa iimpawu ngokunciphisa ukubonakaliswa kwe-histamine yangaphandle, uphando olubonisa ukuba banokunyanga ukunganyamezelani kwe-histamine okanye ukusilela kwe-DAO.

Ukuba ufunyaniswe unganyamezelani nge-histamine okanye ukrokrela ukuba unayo, nxibelelana nengcali yezempilo efanelekileyo ukuba iphuhlise isicwangciso esenzelwe wena ngokweemfuno zakho ezizodwa kunye neenjongo zakho zempilo.

Ukuza kuthi ga ngoku, akukho phando lwenzululwazi lubonisa ukuba izongezo ze-DAO zinokunyanga ukusilela kwe-DAO okanye ukunganyamezelani kwe-histamine.

Unyango lweZondlo kwi-DAO

Ukunganyamezelani kwe-Histamine kunye nokusilela kwe-DAO ziimeko ezinzima kunye nezinto ezininzi ezinefuthe kubukhali beempawu ezinxulumene noko.

Okwangoku, enye yeendlela eziphambili zokunyanga le meko kukutya.

Kuba ukutya okuthile kuyaziwa ukuba kunamanqanaba ahlukeneyo e-histamine, uhlengahlengiso oluthile kwindlela yokutya olunokuthi luphucule ukunganyamezelani kwe-histamine ngokunciphisa ukubekeka kwimithombo yokutya ye-histamine kunye nokutya okutya okunokuthintela ukusebenza kwe-DAO.

Ukuphucula umsebenzi we-DAO

Unyango lwesondlo eyilelwe ukuphucula ukunyamezelana kwe-histamine kunye nomsebenzi we-DAO ufuna ukuqinisekisa ukutya okwaneleyo kwezakha-mzimba ezichaphazelekayo ekwaphuleni i-histamine, kubandakanya ubhedu kunye neevithamini B6 kunye no-C ().

Olunye uphando lukwacebisa ukuba ukutya okwaneleyo kwamafutha asempilweni kunye nezinye izakhamzimba ezinje nge-phosphorus, zinc, magnesium, iron, kunye ne-vitamin B12 -inokudlala indima ekuphuculeni umsebenzi we-DAO ().

Ukutya ikakhulu ukutya okune-histamine esezantsi kunokunciphisa ukubonakaliswa kwe-histamine kunye nokunciphisa ukuqokelelana komzimba wakho. Ukutya okune-histamine ephantsi kubandakanya:

• inyama entsha nentlanzi
• amaqanda
• Uninzi lwemifuno - ngaphandle kwesipinatshi, iitumato, iavokhado kunye nesitshalo seqanda
• Uninzi lweziqhamo ezitsha - ngaphandle kwe-sitrasi kunye namajikijolo
• iioyile ezinjengekhokhonathi kunye neoyile yeoli
• iinkozo, kubandakanya irayisi, iquinoa, umbona, iteff, kunye namazimba

Ukutya ekufuneka sikuphephe

Ukunciphisa okanye ukuphelisa ukutya okuphezulu kwi-histamine okanye ezo zibangela imveliso ye-histamine sesinye isicwangciso sokulawula iimpawu zokunganyamezelani kwe-histamine kunye nemveliso ephantsi ye-DAO.

Ukutya okuqukethe amanqanaba aphezulu e-histamine kwaye kunokubangela ukukhutshwa kwe-histamine kubandakanya ():

• iziselo ezinxilisayo, ezifana nebhiya, iwayini, notywala
• ukutya okunesonka, okunje nge-sauerkraut, i-pickles, iyogathi kunye ne-kimchi
• iqokobhe
• yobisi
• ukutya okudala, okufana netshizi kunye nokutshaya kunye nokuphilisa inyama
• ingqolowa
• amandongomane, anjengamandongomane kunye neecashews
• iziqhamo ezithile, kubandakanya iziqhamo zesitrasi, iibhanana, ipapaya, kunye namaqunube
• imifuno ethile, kubandakanya utamatisi, isipinatshi, isitshalo seqanda, kunye neavokhado
• izongezo ezithile zokutya, imibala, kunye nezinto ezisigcinayo

Kungenxa yokuba ukhetho lokutya luvunyelwe kukutya okune-histamine esezantsi kunokulinganiselwa, unokuba semngciphekweni wokusilela kwesondlo kunye nomgangatho wobomi obuncitshisiweyo (1,).

Ke ngoko, ukutya okune-histamine engqongqo kufuneka kusetyenziswe okwethutyana ukuvavanya iimvakalelo kukutya okuthile.

Abanye abantu abanokunganyamezelani kwe-histamine banokunyamezela izixa ezincinci zokutya okuphezulu-histamine.

Ukutya okunokupheliswa kunokunceda ekuboneni ukuba kukuphi ukutya okubangela ezona mpawu kwaye kufuneka kuthintelwe ngokungenammiselo kwaye abo unokuqhubeka ngokukhuselekileyo nokutya izixa ezincinci.

Ngokufanelekileyo, le nkqubo igqityiwe phantsi kwesikhokelo somboneleli wezempilo ofanelekileyo ukunqanda iingxaki.

Unyango kwizondlo ukuxhasa ukusebenza kwe-DAO kunye nokunciphisa ukubonakaliswa kwe-histamine kubandakanya ukupheliswa kweeprotokholi zokutya kunye nokutya okwaneleyo kwezondlo ezithile ezaziwayo ukuphucula umsebenzi we-DAO.

Amanyathelo okhuseleko kunye neengcebiso zedosi

Akukho ziphumo zibi ziye zaxelwa kwizifundo kwizongezo ze-DAO.

Nangona kunjalo, uphando lusenqabile, ke ukuvumelana okucacileyo ngokubhekisele kumthamo wolu nyango kusafuneka kusekwe.

Uninzi lwezifundo ezikhoyo zisebenzisa iidosi ze-4.2 mg ye-DAO ngexesha ukuya kuthi ga kumaxesha ama-2-3 mihla le ngaphambi nje kokutya (,,).

Ke, iidosi ezifanayo zinokukhuseleka kubantu abaninzi - kodwa oko akuthethi ukuba ayi-100% ngaphandle komngcipheko.

Amanye amazwe afana ne-United States awalawuli izongezo zesondlo. Ke ngoko, ngumbono olungileyo ukuqinisekisa ukuba imveliso oyikhethileyo ihlolwe ukuba isulungekile na kwaye isemgangathweni ngumntu wesithathu, njenge-US Pharmacopeia Convention (USP).

Njalo qhagamshelana nomboneleli wakho wezempilo ngaphambi kokungenisa isongezelelo esitsha kwisondlo sakho.

Imithamo ye-4.2 mg ye-DAO ama-2-3 amaxesha yonke imihla ngaphambi kokutya kuphandwe kungekho ngxelo zokungalunganga. Nangona kunjalo, imvumelwano ecacileyo yedosi ye-DAO ayimiselwanga.

Umgca osezantsi

Izongezo ze-DAO azinakunyanga ukunganyamezelani kwe-histamine okanye ukusilela kwe-DAO kodwa zinokunciphisa iimpawu ngokwaphula imithombo yangaphandle ye-histamine njengaleyo isuka ekutyeni nakwiziselo.

Uphando oluthe kratya luyafuneka ukumisela ukusebenza kwabo, ukhuseleko, kunye nomthamo, nangona izifundo ezikhoyo zinika ingxelo ngeziphumo ezibi.

Qiniseka ukuba ubonisana nokuthetha nomboneleli wezempilo ofanelekileyo ngaphambi kokuba ungeze naluphi na ulongezo okanye amayeza kwindlela yakho yempilo.