I-Eculizumab -Yenzelwe ntoni

Umxholo

• Yenzelwe ntoni
• Ixabiso
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga eziphambili
• Xa ingasetyenziswa

I-Eculizumab yi-monoclonal antibody, ethengiswa ngentengiso phantsi kwegama likaSoliris. Iphucula impendulo yokuvuvukala kwaye inciphise amandla omzimba okuhlasela iiseli zayo zegazi, ibonakaliswe ikakhulu ekulweni isifo esinqabileyo esibizwa ngokuba yi-paroxysmal hemoglobinuria yasebusuku.

Yenzelwe ntoni

Iyeza i-Soliris ibonakalisiwe kunyango lwesifo segazi esibizwa ngokuba yi-paroxysmal nocturnal hemoglobinuria; isifo segazi kunye nezintso ezibizwa ngokuba yi-atypical hemolytic uremic syndrome, apho kunokubakho i-thrombocytopenia kunye ne-anemia, ukongeza kumahlwili egazi, ukudinwa kunye nokungasebenzi kakuhle kwamalungu ahlukeneyo, ikwaboniswa kunyango lweMyasthenia gravis ngokubanzi.

Ixabiso

EBrazil, eli chiza livunyiwe ngu-Anvisa, kwaye lenziwa ukuba lifumaneke yi-SUS ngokusebenzisa ityala, lingathengiswa ezikhemesti.

Kusetyenziswa kwanjani

Eli yeza kufuneka lisetyenziswe njengenaliti esibhedlele. Ngokubanzi, unyango lwenziwa nge-drip kwi-vein, malunga nemizuzu engama-45, kanye ngeveki, iiveki ezi-5, de kube kwenziwe uhlengahlengiso kwidosi ukuba isetyenziswe rhoqo kwiintsuku ezili-15.

Iziphumo ebezingalindelekanga eziphambili

I-Eculizumab ivame ukunyamezeleka, eyona nto ixhaphakileyo ukuqala kwentloko. Nangona kunjalo, iziphumo ebezingalindelekanga ezinje nge-thrombocytopenia, ukunciphisa iiseli ezibomvu zegazi, isisu esibuhlungu, ukuqhina, urhudo, ukugaya okungalunganga, isicaphucaphu, iintlungu esifubeni, ukugodola, umkhuhlane, ukudumba, ukudinwa, ubuthathaka, i-herpes, i-gastroenteritis, ukudumba nako kunokubakho. , isifo samathambo, inyumoniya, i-meningococcal meningitis, iintlungu zemisipha, iintlungu zomqolo, iintlungu zentamo, isiyezi, ukunciphisa incasa, ukurhawuzelela emzimbeni, ukwakhiwa okuzenzekelayo, ukukhohlela, ukuqaqanjelwa ngumqala, impumlo egudileyo, ukurhawuzelela komzimba, ukuwa uboya, ulusu olomileyo.

Xa ingasetyenziswa

I-Soliris akufuneki isetyenziswe kubantu abangadibaniyo nakwezinye izinto zefomyula, kwaye kwimeko yosulelo nge-Neisseria meningitidis engasonjululwanga, abantu abangenalo ugonyo lwe-meningitis.

Eli yeza kufuneka lisetyenziswe kuphela ngexesha lokukhulelwa, phantsi kwengcebiso yezonyango kwaye ukuba kunyanzelekile, kuba lidlula kwi-placenta kwaye linokuphazamisa ukujikeleza kwegazi lomntwana. Ukusetyenziswa kwayo ayiboniswanga ngexesha lokuncancisa, ke ukuba owasetyhini uncancisa, kuya kufuneka ayeke iinyanga ezi-5 emva kokusebenzisa eli yeza.