Yintoni i-sclerosteosis kwaye kutheni isenzeka

Umxholo

• Iimpawu eziphambili
• Kutheni le nto isenzeka
• Unyango lwenziwa njani

I-Sclerosis, ekwabizwa ngokuba sisifo seethambo segranite, sisifo esinqabileyo semfuza esibangela ukwanda kwethambo. Olu tshintsho lubangela amathambo, endaweni yokwehla koxinano kwiminyaka edlulileyo, ukuba aye esiba namandla kwaye axinene, abe namandla kunegranite.

Ke, i-sclerosteosis ithintela ukuqala kwezifo zamathambo ezinje nge-osteoporosis, kodwa ibangela ezinye iinguqulelo, ezinje ngoxinzelelo olwandileyo ngaphakathi kukakayi, olunokuthi, ukuba luyekwanga lunganyangwa, lube lusongela ubomi.

Iimpawu eziphambili

Olona phawu luphambili lwe-sclerosteosis kukonyuka koxinano lwamathambo, nangona kunjalo, zikhona ezinye iimpawu ezinokuthi zikwazise ngesi sifo, njenge:

• Ukudibana kweminwe emi-2 okanye emi-3 ezandleni;
• Utshintsho kubukhulu kunye nobukhulu bempumlo;
• Ukukhula okubaxiweyo kokakayi kunye namathambo obuso;
• Kunzima ukuhambisa ezinye izihlunu zobuso;
• Incam yomnwe egobile ijonge ezantsi;
• Ukungabikho kweenzipho kwiminwe yakho;
• Ukuphakama okungaphezulu komndilili womzimba.

Njengokuba sisifo esinqabe kakhulu, ukuxilongwa kwaso kuyinkimbinkimbi kwaye, ke ngoko, ugqirha unokufuna ukuvavanya zonke iimpawu kunye nembali yeklinikhi, kunye nokwenza iimvavanyo ezininzi, ezinjenge-densimetry yethambo, ngaphambi kokucebisa ukuba kufunyaniswe isifo se-sclerosteosis.

Ngamanye amaxesha, uvavanyo lwemfuzo lunokuyalelwa oluya kuvavanya i-DNA kunye notshintsho olunokwenzeka, kwaye lunokunceda ekuchongeni utshintsho kwi-SOST gene, ebangela esi sifo.

Kutheni le nto isenzeka

Esona sizathu siphambili sesifo sokuqina kwemithambo sisifo esiguqukayo esenzeka kuhlobo lwe-SOST kwaye sinciphisa isenzo se-sclerostin, iprotein ejongene nokwehla kobuninzi bethambo kunye nokonyuka kobomi bonke.

Ngokwesiqhelo, esi sifo sivela kuphela xa kukho iikopi ezimbini zemfuza eziguqulweyo, kodwa abantu abanekopi enye banokuba namathambo omelele kakhulu kunye nomngcipheko ophantsi wezifo zamathambo ezinje nge-osteoporosis okanye i-osteopenia.

Unyango lwenziwa njani

Akukho lunyango lwe-sclerosteosis kwaye, ke, unyango lwayo lwenziwa kuphela ukunciphisa iimpawu ezithile kunye neziphene ezinokuvela ekukhuleni kakhulu kwethambo.

Olunye lweendlela zonyango ezisetyenzisiweyo lutyando, olunokuthi luncede ekunciphiseni imithambo-luvo yobuso kunye nokufumana kwakhona ukuhamba kwemisipha yobuso, okanye ukususa ithambo elingaphezulu ukuze kuncitshiswe uxinzelelo ngaphakathi kolukakayi, umzekelo.

Yiyo ke loo nto, unyango kufuneka luhlale luxoxwa nogqirha ukuvavanya ukuba ngaba lukhona utshintsho olunokuba semngciphekweni wobomi okanye olwehlayo kumgangatho wobomi, kwaye olunokulungiswa.