Uvavanyo lwe-CA 15.3 -lenzelwe ntoni kwaye lwenziwa njani

Umxholo

• Yenzelwe ntoni
• Kwenziwa njani

Uvavanyo lwe-CA 15.3 luvavanyo oluqhelekileyo olucelwa ukuba lubeke esweni unyango kwaye luvavanye ukuphinda umhlaza webele. I-CA 15.3 yiprotein yesiqhelo eveliswa ziiseli zamabele, nangona kunjalo, kumhlaza ukuxinana kwale proteni kuphakame kakhulu, kusetyenziswa njengesiphawuli sethumba.

Ngaphandle kokuba isetyenziswa ngokubanzi kumhlaza wamabele, i-CA 15.3 inokuphakanyiswa kwezinye iintlobo zomhlaza, ezinje ngemiphunga, ipancreas, i-ovary kunye nesibindi, umzekelo. Ke ngoko, kufuneka iyalelwe kunye nezinye iimvavanyo, ezinje ngovavanyo lweemolekyuli ukuvavanya ukubonakaliswa kohlobo lomhlaza wamabele kunye neemvavanyo ezivavanya i-estrogen receptor, i-HER2. Jonga ukuba zeziphi iimvavanyo eziqinisekisa kunye nokufumanisa umhlaza webele.

Yenzelwe ntoni

Uvavanyo lwe-CA 15.3 ikakhulu lusebenza ukuvavanya impendulo kunyango lomhlaza wamabele kunye nokujonga ukuphindeka. Olu vavanyo alusetyenziswanga kuvavanyo, njengoko lunobuntununtunu obuphantsi kunye nokucaciswa. Kukhuthazwa ngokubanzi ngugqirha ukuba enze olu vavanyo ngaphambi kokuqala unyango kunye neeveki ezimbalwa emva kotyando okanye ukuqala kwekhemotherapy, ukujonga ukuba unyango luyasebenza na.

Ukuxinana kwale proteni egazini kunyuswe nge-10% yabasetyhini kwinqanaba lokuqala lomhlaza wamabele kwaye ngaphezulu kwe-70% yabasetyhini abanomhlaza kwinqanaba eliphambili, ngesiqhelo nge-metastasis, ukubonakaliswa ngakumbi kokwenza olu vavanyo abasetyhini abasele banyangwa okanye abafumana unyango lomhlaza.

Kwenziwa njani

Uvavanyo lwenziwa kuphela ngesampulu yegazi lomntu kwaye alufuni lungiselelo. Igazi liyaqokelelwa lize lithunyelwe elebhu ukuze liqwalaselwe kwaye lihlalutywe. Inkqubo yohlalutyo ngokuzenzekelayo iyazenzekela kwaye ivelisa iziphumo ezichanekileyo nezithembekileyo ngexesha elifutshane.

Ixabiso lesalathiso kolu vavanyo li-0 ukuya ku-30 ​​U / mL, amaxabiso angentla koku sele ebonakalisile kukubi. Ukuphakama koxinaniso lwe-CA 15.3 egazini, kokukhona umhlaza webele uqhubela phambili. Ukongeza, ukwanda okuqhubekayo kokuxinana kwale proteni kunokubonisa ukuba umntu akaphenduli kunyango okanye ukuba iiseli zethumba ziyaphinda ziphindaphinde, zibonisa ukubuyela umva.

Ukugxininiswa okuphezulu kwe-CA 15.3 akusoloko kubonisa umhlaza webele, njengoko le protein inokuphakanyiswa nakwezinye iintlobo zomhlaza, ezinje ngemiphunga, i-ovari kunye nomhlaza wecolorectal, umzekelo. Ngesi sizathu, uviwo lwe-CA 15.3 alusetyenziswanga kuvavanyo, kuphela ukujonga isifo.