Ngaba Uncedo lwe-Folic Acid lunokunciphisa iZiphumo zeMethotrexate?

Umxholo

• Yintoni imethotrexate?
• Yintoni ifolate?
• Kutheni le nto ugqirha wam emisela i-methotrexate kunye ne-folic acid kunye?
• Yintoni i-folic acid?
• Ngaba i-folic acid iyayichaphazela indlela i-methotrexate ephatha ngayo i-RA?
• Kutheni kubalulekile ukuba ndinyange iRA yam?
• Yintoni uthatha?

Sibandakanya iimveliso esicinga ukuba ziluncedo kubafundi bethu. Ukuba uthenga amakhonkco kweli phepha, sinokufumana ikhomishini encinci. Nantsi inkqubo yethu.

Yintoni imethotrexate?

Ukuba une-rheumatoid arthritis (RA), ugqirha wakho usenokumisela unyango lwe-methotrexate.

IMethotrexate sesinye seziyobisi ezisetyenziswa kakhulu ukunyanga iRA. Nangona kunjalo, inokunciphisa amanqanaba evithamini ebalulekileyo emzimbeni wakho obizwa ngokuba yifolate.

Oku kukhokelela kwisiphumo esecaleni semethotrexate ebizwa ngokuba kukusilela kwabantu. Ugqirha wakho unokucebisa ukuba uthathe isongezelelo se-folic acid, eyifom eyenziweyo.

Yintoni ifolate?

I-Folate yivithamini B enendima kwimisebenzi emininzi ebalulekileyo emzimbeni wakho. Inceda umzimba wakho wenze iiseli ezibomvu zegazi (RBCs) kunye nezinye iiseli ezisempilweni. Kwakhona kubalulekile ukukhula kwe-DNA kunye nokulungiswa.

I-Folate inokufumaneka kukutya okuninzi ezahlukeneyo. Oku kutya kubandakanya:

• imifuno enamagqabi, njengespinatshi, ibroccoli, kunye neletisi
• okra
• i-asparagus
• ibrussels sprouts
• iziqhamo ezithile, ezinjengeebhanana, iivatala, kunye neelamuni
• iimbotyi, ezifana nee-ertyisi, iimbotyi, neelentile, iimbotyi zesoya, namandongomane
• amakhowa
• inyama, efana nesibindi senkomo kunye nezintso
• Ijusi yeorenji kunye nejusi yetumato

Nangona kulungile ukuba ufumane ifatyana ngokutya okwahlukileyo koku kutya, ukutya nje okuninzi koku kutya akunakwanela ukwenza ifolothi elahlekileyo kwi-methotrexate.

Kutheni le nto ugqirha wam emisela i-methotrexate kunye ne-folic acid kunye?

I-Methotrexate iphazamisa indlela umzimba wakho owaphule ngayo.

Xa uthatha i-methotrexate, unokukhulisa amanqanaba e-folate angaphantsi kunesiqhelo. Kungenxa yokuba i-methotrexate ibangela ukuba umzimba wakho ulahle inkunkuma engaphezulu kunesiqhelo. Esi siphumo sibangela ukusilela komntu.

Ugqirha wakho unokumisela isongezelelo se-folic acid ukunceda ukunqanda ukusilela komntu. Ezinye zeempawu ezibangelwa kukusilela komntu zibandakanya:

• i-anemia, okanye inani elinciphileyo leeseli ezibomvu zegazi (RBCs)
• ubuthathaka nokudinwa
• isicaphucaphu
• ukugabha
• isisu esibuhlungu
• urhudo
• iingxaki zesibindi
• i-stomatitis, okanye izilonda zomlomo

Yintoni i-folic acid?

I-folic acid yindlela eyenziweyo yefolate. Ukuthatha i-folic acid kunokunceda ekwenzeni, okanye ukongeze, ifolothi elahlekileyo emzimbeni wakho xa uthatha i-methotrexate.

Izongezo ze-Folic acid, ezithathwa ngomlomo, zinokunceda ukunciphisa iziphumo ebezingalindelekanga. Ziyafumaneka ukuze zithengwe ekhawuntarini, nokuba zikwi-intanethi okanye kwindawo ekuthengiswa kuyo iziyobisi kwindawo ohlala kuyo.

Thetha nogqirha wakho. Banokumisela umlinganiso we-folic acid ekulungeleyo.

Ngaba i-folic acid iyayichaphazela indlela i-methotrexate ephatha ngayo i-RA?

Ukuthatha i-folic acid nge-methotrexate akukunciphisi ukusebenza kwe-methotrexate kunyango lwe-RA yakho.

Xa usebenzisa i-methotrexate ukunyanga i-RA, inceda ukunciphisa iintlungu kunye nokudumba ngokuthintela iikhemikhali ezithile emzimbeni wakho ezikhokelela kukudumba. I-Methotrexate iyayivimba into, kodwa indlela ephatha ngayo i-RA ibonakala ngathi ayihambelani nokuthintela ubume.

Ke ngoko, ukuthatha i-folic acid ukuyenzela into oyilahlekileyo ekuthatheni i-methotrexate kunceda ukunciphisa iziphumo ebezingalunganga ngaphandle kokuchaphazela unyango lwakho lwe-RA.

Kutheni kubalulekile ukuba ndinyange iRA yam?

I-RA sisifo sokuzimela. Ukuphazamiseka okuzenzekelayo kwenzeka xa amajoni akho omzimba esenza iimpazamo kwizicwili zomzimba wakho zabahlaseli kwaye uwahlasela.

Kwi-RA, amajoni akho omzimba ahlasela ngokukodwa i-synovium, engumbhinqo weembumba ezijikeleze amalungu akho. Ukudumba kolu hlaselo kubangela ukuba i-synovium inyuse.

Ukuba awuyiphathi iRA yakho, le synovium iqina inokubangela intlala kunye nentshabalalo yethambo. Izicubu ezigcina amalungu akho ngokudibeneyo, abizwa ngokuba yimisipha kunye nemisipha, zinokuba buthathaka kwaye zolule.

Oku kunokubangela ukuba amalungu akho alahlekelwe yimilo ngokuhamba kwexesha, enokuchaphazela indlela onokuhamba ngayo.

Ukudumba okunxulunyaniswa neRA kungonakalisa namanye amalungu omzimba ngokunjalo. Oku kubandakanya ulusu lwakho, amehlo, imiphunga, intliziyo, kunye nemithambo yegazi. Ukunyanga i-RA yakho kunokunciphisa ezi ziphumo kunye nokuphucula umgangatho wobomi bakho. Funda ngakumbi malunga nonyango lweRA.

Yintoni uthatha?

Ngamanye amaxesha i-methotrexate ikhokelela ekusweleni komntu, kunokubangela ezinye iziphumo ebezingalunganga. Nangona kunjalo, ezi ziphumo zecala zihlala zithintelwa ngokuthatha i-folic acid.

Ukunyanga i-RA yakho kubaluleke kakhulu, ke kuya kufuneka wenze unyango lwakho lube lula kangangoko. Ukuba ugqirha wakho umisela i-methotrexate kwi-RA yakho, thetha nabo malunga nomngcipheko wokunqongophala komntu kunye nokusetyenziswa kwe-folic acid ukukhusela iziphumo ebezingalindelekanga.