Uvavanyo lwe-Fructosamine: yintoni, xa kubonisiwe kunye nendlela yokuqonda iziphumo
Umxholo
I-Fructosamine luvavanyo lwegazi oluvumela ukuvavanywa kokusebenza konyango kwimeko yeswekile, ngakumbi xa utshintsho lwamva nje lwenziwe kwisicwangciso sonyango, nokuba ngamayeza asetyenzisiweyo okanye ekutshintsheni indlela yokuphila, njengokutya okanye umthambo, umzekelo.
Olu vavanyo luhlala lusetyenziselwa ukuvavanya utshintsho kumanqanaba eswekile ngaphezulu kweeveki ezi-2 okanye ezi-3 ezidlulileyo, kodwa yenziwa kuphela xa kungenakwenzeka ukubeka esweni isifo seswekile ngovavanyo lwe-hemoglobin eglycated, abantu abaninzi abanesifo seswekile abanakuze bathathe uvavanyo lwe-fructosamine .
Kwiimeko ezininzi, olu vavanyo lunokuyalelwa ngexa lokukhulelwa, ukuvavanya rhoqo amanqanaba eswekile okhulelweyo, njengoko iimfuno zakhe ziyahlukahluka ngexesha lokukhulelwa.
Xa kubonisiwe
Uvavanyo lwe-fructosamine lokuvavanya amanqanaba eswekile egazini luboniswa xa umntu enotshintsho kumanqanaba eerythrocyte kunye nehemoglobin, exhaphake kwimeko ye-anemia. Ke, akunakwenzeka ukuba iswekile yegazi ihlolwe kusetyenziswa i-hemoglobin eglycated, kuba amanqanaba eli candelo legazi atshintshiwe.
Ukongeza, uvavanyo lwe-fructosamine luboniswa xa umntu esopha kakhulu, ethe watofelwa igazi kutshanje okanye amanqanaba asezantsi ejikeleza i-iron. Ke, ukusebenza kwe-fructosamine endaweni ye-hemoglobin eglycated kusebenza ngakumbi kuvavanyo lokujikeleza amanqanaba eglucose emzimbeni.
Uviwo lwe-fructosamine lulula kakhulu, lufuna kuphela ukuqokelelwa kwesampulu yegazi encinci ethunyelwa elebhu ukuba ihlolwe, ngaphandle kwesidingo salo naluphi na uhlobo lokulungiselela.
Uviwo lusebenza njani
Kolu hlobo lovavanyo, inani le-fructosamine egazini livavanywa, into eyenziwayo xa iswekile ibopha kwiiproteni zegazi, ezinje ngealbumin okanye ihemoglobin. Ke, ukuba iswekile eninzi egazini, kwimeko yeswekile, ixabiso le-fructosamine liya kuba ninzi, kuba iiproteni ezininzi zegazi ziya kudityaniswa neswekile.
Ukongeza, njengoko iiproteni zegazi zinobomi obumndilili beentsuku ezingama-20 kuphela, amaxabiso avavanywayo ahlala ebonisa isishwankathelo samanqanaba eswekile yegazi kwiiveki ezi-2 ukuya kwezi-3 zokugqibela, evumela ukuvavanya utshintsho olwenziwe ngelo xesha.
Oko kuthethwa sisiphumo
Amaxabiso ekubhekiswa kuwo e-fructosamine kumntu ophilileyo anokwahluka phakathi kwe-205 ukuya kwi-285 micromolecule kwilitha nganye yegazi. Xa la maxabiso avela kwisiphumo somntu onesifo seswekile, oko kuthetha ukuba unyango luyasebenza kwaye, ke, amaxabiso eswekile yegazi alawulwa kakuhle.
Ke, xa iziphumo zoviwo zezi:
- Phezulu: kuthetha ukuba i-glucose ibingalawulwa kakuhle kwezi veki zimbalwa zidlulileyo, ibonisa ukuba unyango alunaziphumo zifunwayo okanye luthatha ixesha elide ukubonisa iziphumo. Isiphumo sisikhulu, kokukhona kusebenza kunyango olusebenzayo.
- Phantsi: kusenokuthetha ukuba iprotein ilahlekile kumchamo kwaye, ke, ugqirha unokuyalela ezinye iimvavanyo ukuqinisekisa iziphumo.
Nokuba siphi na isiphumo, ugqirha unokuhlala e-odola ezinye iimvavanyo ukuba zichonge ukuba ukwahluka kweswekile kungenxa yonyango okanye ezinye iingxaki zempilo, ezinje ngehyperthyroidism, umzekelo.