Umbhali: John Stephens
Umhla Wokudalwa: 26 Eyomqungu 2021
Hlaziya Umhla: 20 Eyenkanga 2024
Anonim
What You Need To Know About Glatiramer Acetate (Copaxone®, Glatopa™)
Ividiyo: What You Need To Know About Glatiramer Acetate (Copaxone®, Glatopa™)

Umxholo

Yintoni iCopaxone?

ICopaxone ligama lonyango elichaza igama likagqirha. Kuvunyiwe ukunyanga iintlobo ezithile ze-multiple sclerosis (MS) kubantu abadala.

Nge-MS, amajoni akho omzimba ahlasela ngempazamo imithambo-luvo yakho. Imithambo-luvo eyonakeleyo iba nengxaki yokunxibelelana nengqondo yakho. Le meko inokubangela iintlobo ezahlukeneyo zeempawu, ezinje ngobuthathaka bemisipha kunye nokudinwa (ukunqongophala kwamandla).

Ngokukodwa, iCopaxone inokusetyenziselwa ukunyanga le miqathango ilandelayo:

  • Isifo esizimeleyo kwiklinikhi (CIS). Nge-CIS, unesiqendu seempawu ezifana ne-MS ezihlala ubuncinci iiyure ezingama-24. I-CIS inakho okanye ayinakuphuhla ibe yi-MS.
  • Ukubuyisela kwakhona i-MS (RRMS). Ngale fomu ye-MS, unamaxesha apho iimpawu zakho ze-MS ziphinda zibuye (ukuvuleka) zilandelwe ngamaxesha apho iimpawu zakho ze-MS zikhululiwe (ziphuculwe okanye zimkile).
  • Iyasebenza Inkqubela phambili yesibini kwi-MS. Ngale fomu ye-MS, imeko iya isiba mandundu, kodwa usenamaxesha okubuyela umva. Ngexesha lokuphinda ubuye, iimpawu zakho ziya zisiba mbi okwethutyana.

Iinkcukacha

ICopaxone iqulethe iziyobisi ze-acetate yeglatiramer esebenzayo. Yindlela yokuguqula isifo kwi-MS. ICopaxone inceda ukumisa amajoni akho omzimba ekuhlaseleni luvo lwakho. Iyeza linokunciphisa inani lokuphinda ubuye kwi-MS kunye nokucutha ukugula kwesifo sakho.


ICopaxone iza njengesisombululo esinikwa ngenaliti engaphantsi (inaliti phantsi kolusu lwakho). Umboneleli wakho wezempilo uya kukubonisa okanye umkhathalele ukuba ulisebenzisa njani iyeza.

ICopaxone iza ngethamo elinye, iisirinji ezikhethiweyo. Itholakala kumandla amabini: 20 mg kunye no-40 mg. Inaliti ye-20-mg ithathwa kube kanye ngosuku, ngelixa inaliti ye-40-mg ithathwa kathathu ngeveki ubuncinci iiyure ezingama-48 ngaphandle.

Ukusebenza ngempumelelo

Ngolwazi malunga nokusebenza kweCopaxone, jonga icandelo "iCopaxone yeMS" apha ngezantsi.

ICopaxone generic

ICopaxone iqulethe iziyobisi ze-acetate yeglatiramer esebenzayo. Iifom zeGeneric zeCopaxone ziyafumaneka, kubandakanya ichiza elenziwa lafana nelo libizwa ngokuba yiGlatopa

Ichiza elenza lafana nelo lenziwe ngumenzi liyikopi ngqo yesiyobisi esisebenzayo kumayeza anegama lophawu. Igeneric ithathwa ngokuba ikhuselekile kwaye iyasebenza njengesiyobisi sokuqala. Iijenerikhi zihlala zibiza iindleko ezingaphantsi kuneziyobisi.

Iziphumo ebezingalindelekanga zeCopaxone

ICopaxone inokubangela iziphumo ebezingalindelekanga ezinobulali okanye ezinobuzaza. Olu luhlu lulandelayo luqulathe ezinye zeziphumo ebezingalindelekanga ezinokubakho ngelixa uthatha iCopaxone. Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga ezinokubakho.


Ngolwazi oluthe kratya malunga neziphumo ebezingalindelekanga zeCopaxone, thetha nogqirha okanye usokhemesti. Banokukunika iingcebiso malunga nendlela yokujongana nayo nayiphi na imiphumela emibi enokuthi ikhathaze.

Phawula: Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) umkhondo weziphumo ebezingalindelekanga ezivunyiweyo. Ukuba ungathanda ukunika ingxelo kwi-FDA isiphumo esibuhlungu onaso ngeCopaxone, ungakwenza oko ngeMedWatch.

Zithatha ixesha elingakanani iziphumo ebezingalindelekanga zeCopaxone?

Iziphumo ebezingalindelekanga onokuthi ube nazo kwiCopaxone, kwaye zihlala ixesha elingakanani, kuxhomekeke kwindlela umzimba wakho ophendula ngayo kwichiza.

Ezinye iziphumo ebezingalindelekanga zinokuhlala ixesha elifutshane. Umzekelo, abanye abantu banempendulo ebizwa ngokuba yi-postinjection reaction emva nje kokufumana inaliti yeCopaxone. Iziphumo zecala zinokubangela iimpawu ezinjengokugungxula, iintlungu zesifuba, kunye nokubetha kwentliziyo ngokukhawuleza. Ukuba une-postinjection reaction kwiCopaxone, iimpawu zakho zinokuhlala ukuya kuthi ga kwiyure eli-1 emva kokuthatha idosi yakho.

Kwelinye icala, ezinye iziphumo ebezingalindelekanga zinokuhlala ixesha elide. Umzekelo, abanye abantu banomonakalo wolusu apho batofa khona iCopaxone kulusu lwabo. Kwaye kwezinye iimeko, umonakalo wolusu obangelwa ziinaliti zeCopaxone unokuba sisigxina. (Ukunceda ukunciphisa umngcipheko wokonakala kolusu, kuya kufuneka ujikeleze iisayithi zenaliti xa uthatha inaliti nganye yeCopaxone.)


Ukuze ufunde okungakumbi malunga nenye yeziphumo ebezingalindelekanga, jonga icandelo leenkcukacha ezingezantsi.

Iziphumo ebezingalindelekanga ezinobulali

Iziphumo ezinobulali zeCopaxone zingaquka:

  • Ukuphendula kwendawo yenaliti, enokubangela ubomvu, iintlungu, ukurhawuzelela, amaqhuma, okanye ukudumba kwindawo yenaliti yakho
  • ukugungxula
  • irhashalala
  • ukuqhawukelwa ngumphefumlo
  • ixhala
  • isicaphucaphu nokugabha
  • ubuthathaka
  • izifo, ezinje ngengqele eqhelekileyo okanye umkhuhlane
  • iintlungu emqolo okanye kwamanye amalungu omzimba wakho
  • Ukubetha kwentliziyo (ukuziva ngathi intliziyo yakho ibaleka, ukubetha, okanye ukubetha)
  • ukubila ngaphezulu kwesiqhelo
  • utshintsho lobunzima, kubandakanya ukutyeba okanye ukunciphisa umzimba

Uninzi lweziphumo ebezingalindelekanga zinokuhamba zingaphelanga iintsuku okanye iiveki ezimbalwa. Kodwa ukuba ziba nzima ngakumbi okanye azihambi, thetha nogqirha wakho okanye usokhemesti.

Iziphumo ebezingalindelekanga ezimandundu

Iziphumo ezibi kakhulu ezivela kwiCopaxone aziqhelekanga, kodwa zinokwenzeka. Shayela ugqirha wakho ngokukhawuleza ukuba unemiphumo emibi. Kodwa fowunela i-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unonyango olungxamisekileyo.

Iziphumo ebezingalindelekanga ezimandundu, ezichazwe ngakumbi apha ngezantsi "Iinkcukacha zeziphumo ebezingalindelekanga," zibandakanya:

  • impendulo ye-postinjection (iimpendulo ezenzeka emzimbeni wakho kungekudala emva kokufumana inaliti yeziyobisi)
  • ukonakala kolusu kwindawo yenaliti yakho
  • iintlungu zesifuba
  • negazi lakho

Iinkcukacha zesiphumo

Unokuzibuza ukuba zenzeka kangaphi ezinye iziphumo ebezingalindelekanga ngeli chiza. Nazi ezinye iinkcukacha kwezinye zeziphumo ebezingalindelekanga ezinokubangelwa leli chiza.

Ukuphendula ngeposenti

Abanye abantu baye baphendule kwiCopaxone kanye emva kokufumana inaliti yeyeza. Esi siphumo sisecaleni sibizwa ngokuba yindlela yokusabela kwisitofu. Ingabangela iimpawu kubandakanya:

  • ukugungxula
  • iintlungu zesifuba
  • ukukhawuleza kwentliziyo
  • Ukubetha kwentliziyo (ukuziva ngathi intliziyo yakho ibaleka, ukubetha, okanye ukubetha)
  • ingxaki yokuphefumla
  • ukuqina emqaleni wakho
  • ixhala
  • i-urticaria (urticaria)

Iimpawu zokuphendula kwi-postinjection zihlala ziphucula kwisithuba seyure enye emva kwenaliti yakho. Ukuba iimpawu zakho zihlala ixesha elide kuneli, okanye zinzima, biza ugqirha wakho ngoko nangoko. Kodwa ukuba iimpawu zakho ziziva zisongela ubomi, tsalela umnxeba ku-911.

Abanye abantu banempendulo ye-postinjection emva kwenaliti yabo yokuqala yeCopaxone. Kodwa abanye abantu banokuphendula emva kwenaliti nganye yeyeza. Kuyenzeka ukuba uqale ukuba nezi mpendulo emva kokuba ufumene inaliti yeCopaxone ngaphambili ngaphandle kwengxaki.

Ukuba ukhathazekile malunga ne-postinjection reaction kunye neCopaxone, thetha nogqirha wakho.

Ngaba ixhaphake kangakanani impendulo yokuposa emva kwesitofu?

Kwizifundo zeklinikhi, malunga neepesenti ezili-16 zabantu abathathe iCopaxone 20 mg yonke imihla babephendula ngokutofa. Xa kuthelekiswa, iipesenti ezi-4 zabantu abathathe indawo ye-placebo (akukho siyobisi sisebenzayo) banempendulo ye-postinjection.

Ukuphendula ngenaliti ngeposi bekungaxhaphakanga kubantu abathathe iCopaxone 40 mg kathathu ngeveki. Umzekelo, ngexesha lophando lweklinikhi, iipesenti ezi-2 baba bantu babenempendulo ye-postinjection. Kolu phando, akukho mntu uthatha indawo ye-placebo owayenokuphendula emva kwesitofu.

Amaqhuma kwindawo yenaliti okanye iintlungu

Iziphumo ebezingalindelekanga eziqhelekileyo zeCopaxone kukusabela kolusu okwenzeka kwiindawo zenaliti. Ezi mpendulo zinokubangela ukutyumka, ukuba bomvu, ukudumba, amaqhuma, iintlungu okanye ukurhawuzelela.

Kwizifundo zeklinikhi, kwaxelwa oku kulandelayo kwendawo yokuphathwa kwenaliti:

  • Ubomvu. Iziphumo ebezingalindelekanga zenzeka kwiipesenti ezingama-22 ukuya kuma-43% yabantu abathathe iCopaxone. Xa kuthelekiswa, i-2% ukuya kwi-10% yabantu abathathe i-placebo (akukho siyobisi sisebenzayo) babebomvu.
  • Intlungu. Iziphumo ebezingalindelekanga zenzeke nge-10% ukuya kwi-40% yabantu abathathe iCopaxone. Xa kuthelekiswa, iipesenti ezi-2 ukuya kuma-20% zabantu abathathe i-placebo baneentlungu.
  • Ukurhawuzelela. Iziphumo ebezingalindelekanga zenzeka nge-6% ukuya kwi-27% yabantu abathathe iCopaxone. Xa kuthelekiswa, i-0% ukuya kwi-4% yabantu abathathe i-placebo babarhawuzelela.
  • Amaqhuma. Iziphumo ebezingalindelekanga zenzeka kwi-6% ukuya kwi-26% yabantu abathathe iCopaxone. Xa kuthelekiswa, i-0% ukuya kwi-6% yabantu abathathe i-placebo banamaqhuma.
  • Ukudumba. Iziphumo ebezingalindelekanga zenzeka kwi-6% ukuya kwi-19% yabantu abathathe iCopaxone. Xa kuthelekiswa, yi-0% ukuya kwi-4% yabantu abathathe i-placebo abanokudumba.

Ngexesha lezifundo, ukuphendulwa kwendawo yenaliti kwakuxhaphake kakhulu ebantwini abathathe iCopaxone 20 mg yonke imihla kunokuba babenjalo kubantu abathathe iCopaxone 40 mg kathathu ngeveki.

Ukuba unendawo yokuphendula ngenaliti kwiCopaxone, impendulo kufuneka inciphise kwiintsuku nje ezimbalwa. Kodwa ukuba ayenzi njalo okanye iimpawu zakho zinzima, biza ugqirha wakho.

Ukonakala kolusu kwindawo yenaliti

Rhoqo, inaliti yeCopaxone inokubangela ukonakala kwesiza kwiinaliti zakho. Ngamanye amaxesha, umonakalo wolusu obangelwa ziinaliti zeCopaxone unokuba sisigxina.

Imizekelo yomonakalo wolusu onokuthi wenziwe ngeCopaxone ibandakanya:

  • Lipoatrophy. Nge-lipoatrophy, umaleko onamafutha phantsi kolusu lwakho wonakele. Lo monakalo unokubangela ukuba kwenziwe imingxunya esisigxina kulusu lwakho. Kwizifundo zeklinikhi, i-lipoatrophy yenzekile kwi-2% yabantu abathathe iCopaxone 20 mg yonke imihla. Kwaye kwenzeka kwi-0.5% yabantu abathathe iCopaxone 40 mg kathathu ngeveki. Akukho mntu uthathe i-placebo (akukho siyobisi sisebenzayo) wayene-lipoatrophy.
  • I-necrosis yolusu. Ngolusu i-necrosis, ezinye iiseli zolusu ziyafa. Le meko inokubangela iindawo zolusu lwakho ukuba zibonakale zimdaka okanye zimnyama. Esi sisiphumo secala esinqabileyo esixeliweyo kuphela ukusukela oko iCopaxone yakhutshelwa kwintengiso. Kwaye akwaziwa ngokuthe ngqo ukuba imeko yenzeka kangaphi kubantu abasebenzisa iCopaxone.

Unokuwunciphisa umngcipheko we-lipoatrophy kunye necrosis yesikhumba ngokulandela ngononophelo imiyalelo yomboneleli wezempilo kwiinaliti zeCopaxone. Umzekelo, kubalulekile ukuba ungafaki idosi kwindawo enye emzimbeni wakho kwidosi nganye. Endaweni yoko, kuya kufuneka ujikeleze indawo yakho yenaliti ngalo lonke ixesha uthatha idosi yeCopaxone.

Ukuba unenkxalabo malunga nomonakalo wesikhumba ngelixa usebenzisa iCopaxone, thetha nogqirha wakho.

Iintlungu zesifuba

Kungenzeka ukuba ube nesifuba esifubeni njengenxalenye yempendulo ye-postinjection kwiCopaxone. Ngempendulo ye-postinjection, uneempawu ezithile, ezinjengeentlungu zesifuba, kanye emva kokuthatha idosi yeCopaxone. (Jonga icandelo elingentla ngolwazi malunga nokusabela kwisitofu.)

Nangona kunjalo, abanye abantu abathatha iCopaxone baneentlungu esifubeni ezingenzeki kanye emva kokufumana inaliti yeyeza. Kwaye iintlungu zesifuba kulandela inaliti yeCopaxone ayisoloko isenzeka nezinye iimpawu.

Kwizifundo zeklinikhi, malunga ne-13% yabantu abathathe iCopaxone 20 mg yonke imihla babeneentlungu esifubeni. Kwaye malunga neepesenti ezi-2 zabantu abathathe iCopaxone 40 mg kathathu ngeveki babeneentlungu esifubeni. Xa kuthelekiswa, iintlungu zesifuba zichazwe kwi-1% ukuya kwi-6% yabantu abathathe indawo ye-placebo (akukho siyobisi sisebenzayo). Kwezi zifundo, enye yale ntlungu yesifuba yayihambelana nokusabela emva kokubhengezwa. Kodwa kwiimeko ezininzi, kwakungahambelani nokusabela kwisitofu.

Ukuba unentlungu esifubeni ngelixa uthatha iCopaxone, kufuneka ihambe ngokukhawuleza. Nangona kunjalo, ukuba unentlungu ehlala ixesha elide kunemizuzu embalwa okanye ibuhlungu, biza ugqirha ngendlela elungileyo. Kwaye ukuba iintlungu zakho ziziva zisongela ubomi, tsalela umnxeba ku-911.

Ukuphendula ngokuchaseneyo

Njengokuba kuninzi lweziyobisi, abanye abantu banokuphendula emva kokuthatha iCopaxone. Kodwa akwaziwa ukuba kukangaphi ukungabikho komzimba xa kusenzeka kubantu abasebenzisa eli chiza.

Iimpawu zokuphendula kancinci kunokubandakanya:

  • irhashalala
  • ukucheba
  • ukucoca (ukufudumala nokubomvu kwesikhumba sakho)

Impendulo eyingozi kakhulu inqabile kodwa inokwenzeka. Iimpawu zokungaziphathi kakuhle kunokubandakanya:

  • ukudumba phantsi kolusu lwakho, ikakhulu kwiinkophe zakho, imilebe, izandla, okanye iinyawo
  • ukudumba kolwimi lwakho, umlomo, okanye umqala
  • ingxaki yokuphefumla

Biza ugqirha wakho ngoko nangoko ukuba uneempendulo ezigwenxa zeCopaxone. Kodwa fowunela i-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unonyango olungxamisekileyo.

Ukutyeba okanye ukunciphisa umzimba

Abanye abantu abathatha iCopaxone baye bafumana ubunzima. Kwizifundo zonyango, iipesenti ezi-3 zabantu abathathe iyeza bafumana ubunzima. Xa kuthelekiswa, i-1% yabantu abathathe indawo ye-placebo (akukho siyobisi sisebenzayo) bafumana ubunzima.

Nangona kunjalo, ukuzuza ubunzima kunokunxulumana ne-multiple sclerosis (MS) uqobo. Umzekelo, ezona mpawu ziqhelekileyo ze-MS kukudinwa (ukunqongophala kwamandla) kunye nengxaki yokuhamba. Kwaye zombini ezi mpawu zinokukwenza ukuba usebenze kancinci kunesiqhelo, oko kunokukhokelela ekuzuzeni ubunzima.

Kubalulekile ukuba uqaphele ukuba ii-corticosteroids, ezisetyenziselwa ukunceda ukunyanga ukuqaqanjelwa kweempawu ze-MS, kunokubangela ukutyeba.

Kwelinye icala, kuye kwakho neengxelo zokulahleka kwesisindo kubantu abasebenzisa iCopaxone. Nangona kunjalo, ezi ngxelo zazinqabile. Ayaziwa ukuba kuncipha kangaphi kubantu abasebenzisa iCopaxone, okanye ukuba isiphumo secala sibangelwa yiCopaxone.

Ukuba unomdla malunga notshintsho kubunzima bakho ngelixa uthatha iCopaxone, thetha nogqirha wakho. Banokucebisa ngokutya kunye neengcebiso zokuzilolonga ukukunceda ulawule ubunzima bomzimba obunempilo kuwe.

Uxinzelelo

Abanye abantu banokuba noxinzelelo ngelixa bethatha iCopaxone. Kwizifundo, abanye abantu abathatha iCopaxone baxele ukuba banexinzelelo. Nangona kunjalo, akwaziwa ukuba kaninzi kangakanani le mpembelelo yecala yenzekile, okanye ukuba ibangelwa yiCopaxone.

Nangona kunjalo, uphando olutshanje lufumene ukuba iCopaxone ayinyusi umngcipheko wokudakumba kubantu abane-MS. Kwaye olunye uphononongo lubonise ukuba iCopaxone khange ibe mandundu ngakumbi iimpawu zoxinzelelo kubantu esele benayo le meko.

Kubalulekile ukuba uqaphele ukuba ukudakumba kuqhelekile kubantu abane-multiple sclerosis (MS). Umzekelo, uxinzelelo lwenzeka malunga nama-40% ukuya kuma-60% abantu abane-MS ngaxa lithile ngexesha lokuphila kwabo.

Ukuba uziva uxinezelekile ngelixa uthatha iCopaxone, thetha nogqirha wakho. Zininzi iindlela zonyango ezikhoyo ezinokukunceda ulawule imeko. Kwaye ugqirha wakho unokucebisa ukuba loluphi ukhetho lonyango olulungele wena.

Ukulahleka kweenwele (hayi isiphumo esisecaleni)

Ukulahleka kweenwele akuzange kubonwe kubantu abathathe iCopaxone ngexesha lokuqala kwezifundo zeklinikhi.

Nangona kunjalo, ukulahleka kweenwele kuyimpembelelo yecala lokunyanga iziyobisi, ngamanye amaxesha ezisetyenziselwa ukunyanga i-multiple sclerosis (MS). La machiza aquka i-mitoxantrone kunye ne-cyclophosphamide. Kodwa gcinani engqondweni ukuba iCopaxone ayisosisiyobisi sokuzikhusela.

Ukuba unenkxalabo malunga nokulahleka kweenwele ngelixa uthatha iCopaxone, thetha nogqirha wakho. Banokukunceda ufumane iindlela zokulawula iziphumo ebezingalindelekanga.

Ungayithatha njani iCopaxone

Kuya kufuneka uthathe iCopaxone ngokwemiyalelo kagqirha wakho okanye yezempilo.

ICopaxone ithathwa ngenaliti engaphantsi (inaliti phantsi kolusu lwakho). Umboneleli wakho wezempilo uya kukufundisa okanye umkhathalele ukuba ulisebenzise njani iyeza. Kwaye xa uqala unyango lweCopaxone, ugqirha wakho okanye umongikazi uya kukunceda ukukunika inaliti yakho yokuqala.

ICopaxone iza njengesisombululo ngaphakathi kwidosi enye, iisirinji ezikhethiweyo ezinenaliti eqhotyoshelweyo. Ukuba awukhululekanga xa usebenzisa iisirinji, buza ugqirha wakho ngesixhobo esikhethekileyo, esibizwa ngokuba ezenzekelayoject 2 yesirinji yeglasi.

Sebenzisa i ezenzekelayoject 2, uya kubeka isirinji ekhethiweyo yeCopaxone ngaphakathi kwesixhobo. Inkqubo ye- ezenzekelayoject I-2 ifihla inaliti yesirinji kwaye ikuvumela ukuba utofe ichiza ngokucinezela iqhosha, endaweni yokutyhala phantsi kwisirinji.

Imiyalelo yokufaka idosi yeCopaxone inikwe kwiphepha lephepha elivela kwikhemesti yakho neCopaxone.

Ukongeza, umvelisi weziyobisi ukwanika isikhokelo ngenaliti kunye nevidiyo yokufundisa ngenyathelo nenyathelo. Ezi zixhobo zichaza ngakumbi malunga nendlela yokusebenzisa iisirinji zeCopaxone kunye ezenzekelayoject 2 isixhobo. Kwaye bachaza ubungakanani benaliti ekufuneka uyikhethile xa usebenzisa i ezenzekelayoject 2 isixhobo.

Iindawo zenaliti yeCopaxone

Ungayifaka iCopaxone phantsi kolusu kwezi ndawo zilandelayo zomzimba wakho:

  • isisu sakho (isisu), ukuba uyakuphepha ukujova kwindawo engaphakathi kwee-intshi ezimbini zesisu sakho
  • umphambili wamathanga akho, ukuba ufakela kwindawo emalunga nee-intshi ezimbini ngaphezulu kwedolo lakho kunye nee-intshi ezimbini ezantsi kwe-groin yakho
  • umva wesinqe sakho ezantsi kwesinqe sakho
  • umva weengalo zakho ezingasentla

Thetha nogqirha wakho malunga nokuba yeyiphi kwezi ndawo inaliti efanelekileyo kuwe. Gcina ukhumbula ukuba ngalo lonke ixesha ufaka idosi yeCopaxone, kuya kufuneka ujikeleze indawo yenaliti oyisebenzisayo. Sukusebenzisa indawo yenaliti efanayo ngaphezulu kwesinye ngeveki.

Kuyanceda ukugcina irekhodi leendawo zenaliti ozisebenzisela idosi nganye yeCopaxone. Ngapha koko, kukho usetyenziso lweCopaxone tracker olufumanekayo kwiwebhusayithi yomenzi enokukunceda wenze oku.

Iingcebiso ngokuthatha iCopaxone

Xa usebenzisa iCopaxone, gcina ezi ngcebiso zilandelayo engqondweni:

  • Thatha iCopaxone ngaphandle kwefriji malunga nemizuzu engama-20 ngaphambi kokuba ucwangcise ukufaka idosi yakho. Oku kunika ixesha leziyobisi ukufudumala ukuya kubushushu begumbi, elenza ukuba inaliti ikhululeke ngakumbi kuwe.
  • Inaliti yeCopaxone kufuneka inikwe kuphela phantsi kolusu lwakho. Musa ukulifaka eli chiza komnye wemithambo yakho okanye izihlunu.
  • Musa ukufaka iCopaxone kwiindawo zesikhumba sakho ezibomvu, ezidumbileyo, ezinamaqhuma, ezinamanxeba, okanye ezinemingxunya. Kulumkele ukufaka inaliti kwiindawo zolusu ezineempawu zokuzalwa, ii-stretch mark, okanye ii-tatoo.
  • Musa ukurabha okanye uhlikihle indawo yakho yenaliti yeCopaxone ubuncinci iiyure ezingama-24 emva kokuba utofile ichiza.

Nini ukuthatha

Xa uza kuyithatha iCopaxone ixhomekeke ekubeni usebenzisa eliphi ichiza. Iishedyuli zedosi zeCopaxone zezi zilandelayo:

  • ICopaxone 20 mg. Ukuba usebenzisa la mandla, uya kulifaka iyeza kube kanye ngemini, ngexesha elifanayo yonke imihla. Ayinamsebenzi ukuba ukhetha ixesha elingakanani, ukuba nje uyahambelana suku ngalunye.
  • ICopaxone 40 mg. Ukuba usebenzisa la mandla, uya kulifaka iyeza kathathu ngeveki. Umzekelo, unokwenza iinaliti zakho ngoMvulo, uLwesithathu nangoLwesihlanu. Qiniseka nje ukuba inaliti zithathwa ubuncinci iiyure ezingama-48 ngokwahlukana.

Ukukunceda uqiniseke ukuba awuphosi idosi, zama ukuseta isikhumbuzi kwifowuni yakho. Izikhumbuzo zinokuseta kwi-Copaxone tracker app.

Umthamo weCopaxone

Olu lwazi lulandelayo luchaza iidosi eziqhelekileyo ezisetyenziswayo okanye ezicetyiswayo. Nangona kunjalo, qiniseka ukuthatha idosi ekumisela ugqirha wakho. Ugqirha wakho uya kugqiba eyona milinganiselo ilungele iimfuno zakho.

Iifom zamachiza kunye namandla

ICopaxone iza njengethamo elinye, iisirinji ezikhethiweyo. Itholakala kumandla amabini: 20 mg kunye no-40 mg.

Isisombululo se-MS

ICopaxone ineedosi ezicetyiswayo zilandelayo ze-multiple sclerosis (MS):

  • 20 mg ithathwa kanye ngemini
  • I-40 mg ithathwe kathathu ngeveki

Ugqirha wakho unokumisela enye yezi shedyuli zedosi, kuxhomekeke kwelona lilungileyo kwimeko yakho eyahlukileyo.

Kuthekani ukuba ndiphose idosi?

Yintoni omele uyenze xa uphoswa yidosi yeCopaxone ixhomekeke kwithamo leziyobisi ozithathayo. Apha ngezantsi, sichaza ukuba senze ntoni kwidosi nganye ekhuthazwayo.

Ungatsalela umnxeba kwiofisi kagqirha wakho ukuba uphosa idosi yeCopaxone kwaye awuqinisekanga ukuba wenzeni. Ugqirha wakho okanye abasebenzi babo bezonyango banokucebisa xa kufanelekile ukuba uthathe idosi yakho elandelayo.

Kwaye ukunceda uqiniseke ukuba awuphosi idosi, zama ukuseta isikhumbuzi kwifowuni yakho, okanye usebenzise i-Copaxone tracker app.

Idosi ephosiweyo yeCopaxone 20 mg yonke imihla

Ukuba uhlala uthatha iCopaxone 20 mg yonke imihla, thatha idosi ephosiweyo ngokukhawuleza nje ukuba ukhumbule. Kodwa ukuba ikufutshane nedosi yakho elandelayo ecwangcisiweyo kunedosi ephosiweyo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Musa ukuthatha iidosi ezimbini ngokudibeneyo ukwenza idosi ephosiweyo.

Idosi ephosiweyo yeCopaxone 40 mg kathathu ngeveki

Ukuba uhlala uthatha iCopaxone 40 mg kwaye uphoswa yidosi, yithathe ngosuku olulandelayo ngexesha lakho eliqhelekileyo. Emva koko thatha idosi yakho elandelayo kwiintsuku ezi-2 emva kwexesha lakho eliqhelekileyo. Zama ukubuyela kwishedyuli yakho kwiveki elandelayo. Kodwa khumbula, kufuneka kusoloko kukho ubuncinci iiyure ezingama-48 phakathi kweedosi zakho.

Umzekelo, ukuba uhlala uthatha iCopaxone ngoMvulo, uLwesithathu nangoLwesihlanu, kodwa uyiphose idosi yakho yangoMvulo, thatha idosi yakho ephosiweyo ngoLwesibini. Emva koko thabatha yonke imithamo yakho kuloo veki ngoLwesine nangoMgqibelo. Kwiveki elandelayo, ungabuyela kwishedyuli yakho yesiqhelo.

Ngaba kuya kufuneka ndisebenzise eli chiza ixesha elide?

ICopaxone yenzelwe ukuba isetyenziswe njengonyango lwexesha elide. Ukuba wena nogqirha ugqibe ukuba iCopaxone ikhuselekile kwaye iyasebenza kuwe, uya kuyithatha ixesha elide.

Ezinye iindlela zeCopaxone

Amanye amachiza akhoyo anokunyanga i-multiple sclerosis (MS), kunye nesifo esizimeleyo sonyango (CIS). (I-CIS yimeko ebangela iimpawu ezifana ne-MS.)

Ezinye iziyobisi ezinokuthi zilungele wena zingcono. Ukuba unomdla wokufumana enye indlela yeCopaxone, thetha nogqirha wakho. Banokukuxelela ngamanye amayeza anokukusebenzela.

Imizekelo yezinye iziyobisi ezingasetyenziselwa ukunyanga i-MS okanye i-CIS zibandakanya:

  • ii-corticosteroids, ezisetyenziselwa ukunyanga iimpawu ze-MS okanye iziqendu ze-CIS, ezinje:
    • imethylprednisolone (iMedrol)
    • i-prednisone (iRayos)
  • Unyango lwezifo ezithathwa ngomlomo, ezinje:
    • idimethyl fumarate (Tecfidera)
    • diroximel fumarate (ubungakanani)
    • fingolimod (iGilenya)
    • I-siponimod (iMayzent)
    • iteriflunomide (Aubagio)
  • Unyango lokuguqula izifo oluthathwa ngokuzitofa ngokwakho, njenge:
    • I-glatiramer acetate (iGlatopa)
    • I-interferon beta-1a (iAvonex, iRebif)
    • I-interferon beta-1b (iBetaseron, iExtavia)
    • I-peferlated interferon beta-1a (iPlegridy)
  • Unyango oluguqula isifo olunikwa ngaphakathi (lujojowe emthanjeni wakho), njenge:
    • alemtuzumab (Lemtrada)
    • natalizumab (iTysabri)
    • ocrelizumab (Ocrevus)

ICopaxone vs Glatopa

Usenokuzibuza ukuba iCopaxone ithelekiswa njani namanye amayeza anikwe ukusetyenziswa okufanayo. Apha sijonga indlela iCopaxone kunye neGlatopa ezifanayo kunye ezahlukeneyo.

Izithako

I-Copaxone kunye ne-Glatopa zombini zineziyobisi ezifanayo: i-glatiramer acetate.

Nangona kunjalo, ngelixa iCopaxone ligama elinegama lophawu, iGlatopa luhlobo oluthile lweCopaxone. Ichiza elenza lafana nelo lenziwe ngumenzi liyikopi ngqo yesiyobisi esisebenzayo kumayeza anegama lophawu.

Sebenzisa

ICopaxone kunye neGlatopa zombini zivunyiwe ukunyanga iindlela ezithile ze-multiple sclerosis (MS) kubantu abadala.

Ngokukodwa, iCopaxone kunye neGlatopa zinokusetyenziselwa ukunyanga le miqathango ilandelayo:

  • Isifo esizimele sodwa (CIS)
  • Ukubuyela kwakhona kwi-MS (RRMS)
  • i-MS esebenzayo (i-SPMS) yesibini esebenzayo

ICopaxone kunye neGlatopa zombini zibizwa ngokuba ziziyobisi eziguqula izifo. Basebenza ngokunceda ukunqanda amajoni akho omzimba ekuhlaseleni imithambo-luvo yakho. La machiza anokunciphisa inani lokuphinda ubuye kwi-MS kwaye ucothise isifo sakho ukuba singabi mandundu.

Amandla neziyobisi

Zombini iCopaxone kunye neGlatopa ziza njengezisombululo ngaphakathi kwidosi enye, iisirinji ezikhethiweyo. Zinikwe nganye ngenaliti engaphantsi (inaliti phantsi kolusu lwakho). Kuxhomekeke kumandla echiza amiselwe ngugqirha wakho, uya kuthatha iyeza ngalinye nokuba kanye ngosuku okanye kathathu ngeveki.

Umboneleli wakho wezempilo uyakukufundisa okanye umkhathalele ukuba ungalifaka njani iyeza.

Ukusebenza kunye nokukhuseleka

Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) luthatha i-genics ukuba ikhuseleke kwaye isebenze njengesiyobisi sokuqala. Oku kuthetha ukuba iGlatopa ithathwa njengefanelekileyo ekunyangeni i-MS kunye neCIS njengeCopaxone. Ikwathetha ukuba iCopaxone kunye neGlatopa zombini zinokubangela iziphumo ezifanayo.

Ukufunda malunga neziphumo ebezingalindelekanga ezinobuzaza nezinobuzaza zeCopaxone, jonga kwicandelo “leCopaxone”.

Iindleko

ICopaxone sisiyobisi esinegama lophawu, ngelixa iGlatopa inguhlobo lweCopaxone. Amayeza egama leBrand ahlala axabisa ngaphezu kwegeneric.

Ngokwengqikelelo yeGoodRx.com, iGlatopa ixabisa kakhulu kunexabiso leCopaxone. Kodwa elona xabiso uza kulihlawula nokuba leliphi na ichiza lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

ICopaxone vs iTecfidera

Usenokuzibuza ukuba iCopaxone ithelekiswa njani namanye amayeza anikwe ukusetyenziswa okufanayo. Apha sijonga indlela iCopaxone kunye neTecfidera ezifanayo kunye ezahlukeneyo.

Izithako

I-Copaxone iqulethe i-acetate ye-glatiramer, ngelixa i-Tecfidera iqulethe i-dimethyl fumarate.

Sebenzisa

ICopaxone kunye neTecfidera zombini zivunyiwe ukunyanga iindlela ezithile ze-multiple sclerosis (MS) kubantu abadala.

Ngokukodwa, iCopaxone kunye neTecfidera zingasetyenziselwa ukunyanga le miqathango ilandelayo:

  • Isifo esizimele sodwa (CIS)
  • Ukubuyela kwakhona kwi-MS (RRMS)
  • i-MS esebenzayo (i-SPMS) yesibini esebenzayo

ICopaxone kunye neTecfidera zombini zibizwa ngokuba ziziyobisi eziguqula izifo. Basebenza ngokunceda ukumisa amajoni akho omzimba ekuhlaseleni imithambo-luvo yakho. La machiza anokunciphisa inani lokuphinda ubuye kwi-MS kwaye ucothise isifo sakho ukuba singabi mandundu.

Iifom zeziyobisi kunye nolawulo

ICopaxone iza njengesisombululo ngaphakathi kwidosi enye, iisringana ezikhethiweyo. Kuthathwe ngenaliti engaphantsi (inaliti phantsi kolusu lwakho). Kuxhomekeke kumandla eziyobisi amiselweyo ugqirha wakho, inokuthathwa kube kanye ngosuku okanye kathathu ngeveki. Umboneleli wakho wezempilo uya kukufundisa okanye umkhathalele ukuba ulisebenzise njani iyeza.

I-Tecfidera, ngakolunye uhlangothi, iza njengama-capsules athathwa ngomlomo. Kuthathwa kabini ngosuku.

Iziphumo kunye neengozi

ICopaxone kunye neTecfidera zombini zineziyobisi eziguqula isifo. Nangona kunjalo, la machiza asebenza ngeendlela ezahlukeneyo emzimbeni wakho. ICopaxone kunye neTecfidera kunokubangela ezinye iziphumo ebezingalindelekanga ezifanayo. Apha ngezantsi kunemizekelo yeziphumo ebezingalindelekanga.

Iziphumo ebezingalindelekanga ezinobulali

Olu luhlu luqulathe ukuya kuthi ga kwi-10 yeziphumo ebezingalindelekanga eziqhelekileyo ezinokuthi zenzeke ngeCopaxone, kunye neTecfidera, okanye zombini iCopaxone kunye neTecfidera (xa zithathwa ngokwahlukeneyo).

  • Ngaba kunokwenzeka neCopaxone:
    • ukusabela kwendawo yenaliti, enokubangela ubomvu, iintlungu, ukurhawuzelela, amaqhuma, okanye ukudumba kwindawo yenaliti yakho
    • ukuqhawukelwa ngumphefumlo
    • ixhala
    • ubuthathaka
    • usulelo, ezinje ngengqele eqhelekileyo kunye nomkhuhlane
    • iintlungu emqolo okanye kwamanye amalungu omzimba wakho
    • Ukubetha kwentliziyo (ukuziva ngathi intliziyo yakho ibaleka, ukubetha, okanye ukubetha)
    • ukubila ngaphezulu kwesiqhelo
    • utshintsho lobunzima, kubandakanya ukutyeba okanye ukunciphisa umzimba
  • Inokwenzeka ngeTecfidera:
    • isisu (isisu) iintlungu
    • urhudo
    • ukuqunjelwa
  • Inokwenzeka kunye neCopaxone kunye neTecfidera:
    • ukugungxula
    • isicaphucaphu nokugabha
    • irhashalala

Iziphumo ebezingalindelekanga ezimandundu

Olu luhlu lunemizekelo yeziphumo ebezingalindelekanga ezinokubakho ngeCopaxone, kunye neTecfidera, okanye zombini iziyobisi (xa zithathwa ngokwahlukeneyo).

  • Ngaba kunokwenzeka neCopaxone:
    • impendulo yokuposa ngenaliti (iimpendulo ezenzeka ngaphakathi komzimba wakho kwakamsinya emva kokufumana inaliti yeziyobisi)
    • iintlungu zesifuba
    • ukonakala kolusu kwindawo yenaliti yakho
  • Inokwenzeka ngeTecfidera:
    • I-lymphopenia (yehla inqanaba leeseli ezimhlophe ezibizwa ngokuba zii-lymphocyte)
    • inkqubela phambili ye-leukoencephalopathy (PML) eqhubekayo, esisifo esisongela ubomi kwingqondo yakho
    • ezinye izifo ezinzulu, ezinjenge-shingles (usulelo olubangelwa yintsholongwane ye-herpes zoster)
    • ukulimala kwesibindi
  • Inokwenzeka kunye neCopaxone kunye neTecfidera:
    • negazi lakho kakhulu

Ukusebenza ngempumelelo

ICopaxone kunye neTecfidera zombini zivunyiwe ukunyanga iifom ezithile ze-MS kunye neCIS. La machiza khange athelekiswe ngokuthe ngqo kwizifundo zeklinikhi. Kodwa izifundo ezahlukileyo zifumene iCopaxone kunye neTecfidera ukuba isebenze ekunyangeni le miba.

Olunye uphononongo lwezifundo lufumanise ukuba iTecfidera yayisebenza ngakumbi kuneCopaxone ekunciphiseni inani lokuphinda ubuye kwi-MS kunye nokunciphisa ukwanda kokukhubazeka okubangelwa yi-MS.

Ukongeza, olunye uphando lufumanise ukuba iTecfidera isebenze ngakumbi kuneCopaxone ekunciphiseni inani lokuphinda ubuye kwi-MS. Nangona kunjalo, olu phando lufumanise ukuba la machiza ayesebenza ngokufanayo ekunciphiseni ukwanda kokukhubazeka okubangelwa yi-MS.

Ukuba unomdla wokuthatha elinye lala machiza kwi-MS, thetha nogqirha wakho. Banokucebisa ukuba leliphi iyeza elingakulungela.

Iindleko

ICopaxone kunye neTecfidera zombini zineziyobisi ezinamagama. ICopaxone ikwafumaneka kwifom yesiqhelo. Okwangoku azikho iifom zohlobo lweTecfidera ezikhoyo. Amayeza egama leBrand ahlala exabisa ngaphezu kwegeneric.

Ngokwengqikelelo kwi-WellRx.com, iTecfidera ixabisa kakhulu kuneendleko zeCopaxone. Kodwa elona xabiso uza kulibhatala nokuba leliphi ichiza lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

ICopaxone yeMS

Ulawulo lokutya kunye neziyobisi (i-FDA) livuma amayeza amiselweyo anjengeCopaxone ukunyanga iimeko ezithile. ICopaxone inokusetyenziselwa ngaphandle kwelebheli yezinye iimeko. Ukusetyenziswa kwelebula engekho xa kusebenze iyeza elamkelweyo ukunyanga imeko enye lisetyenziselwa ukunyanga imeko eyahlukileyo.

I-Copaxone ivunyiwe yi-FDA ukunyanga iifom ezibuyayo ze-multiple sclerosis (MS) kubantu abadala. Iyeza liyakwamkelwa ukunyanga isifo sodwa sonyango (i-CIS) kubantu abadala. (I-CIS yimeko ebangela iimpawu ezifana ne-MS.)

Ngokukodwa, iCopaxone inokusetyenziselwa ukunyanga le miqathango ilandelayo:

  • ICIS. Nge-CIS, unesiqendu seempawu ezifana ne-MS ezihlala ubuncinci iiyure ezingama-24. I-CIS inakho okanye ayinakuphuhla ibe yi-MS.
  • Ukubuyisela kwakhona i-MS (RRMS). Ngale fomu ye-MS, unamaxesha apho iimpawu zakho ze-MS ziphinda zibuye (ukuvuleka) zilandelwe ngamaxesha apho iimpawu zakho ze-MS zikhululiwe (ziphuculwe okanye zimkile).
  • Iyasebenza Inkqubela phambili yesibini ye-MS (SPMS). Ngale fomu ye-MS, imeko yakho iya isiba mandundu, kodwa usenamaxesha okubuyela umva. Ngexesha lokuphinda ubuye, iimpawu zakho ziya zisiba mbi okwethutyana.

Nge-MS, amajoni akho omzimba ahlasela ngempazamo imithambo-luvo yakho. Imithambo-luvo eyonakeleyo iba nengxaki yokunxibelelana nengqondo yakho. Le meko inokubangela iintlobo ezahlukeneyo zeempawu, kuxhomekeke ekubeni yeyiphi imithambo eyonakalisiweyo.

Ngeendlela ezibuyayo ze-MS, uneziqendu zomonakalo wemithambo-luvo obangela iimpawu ezintsha ze-MS. Okanye unokuba namaxesha xa iimpawu zakho ze-MS zibuya okanye ziba mandundu emva kokuba ziphuculwe.

ICopaxone lonyango oluguqula isifo. Isebenza ukunyanga i-MS kunye neCIS ngokunceda ukumisa amajoni akho omzimba ekuhlaseleni imithambo-luvo yakho. Ngokwenza oku, iyeza linokunciphisa inani lokuphinda ubuye kwi-MS kwaye ucothise ukwanda kwesifo sakho.

Ukusebenza kwe-MS

Kwizifundo ezininzi zeklinikhi, iCopaxone yayisebenza ngokunyanga iifom zokubuyisela kwakhona kwi-MS. Ngokukodwa, iCopaxone yehlise inani le-MS lokuphinda ubuye ebantwini. Kwaye iyeza lanciphisa inani lezilonda zobuchopho (indawo yomonakalo wemithambo-luvo) abantu ababenayo kwesi sifo. ICopaxone ikwacothisile i-MS ekubeni iye isiba mandundu ebantwini abasebenzisa iziyobisi.

Umzekelo, izifundo ezibini zijonge ukusebenza kweCopaxone 20 mg yonke imihla kubantu abane-MS. Ngaphezulu kweminyaka emi-2 yonyango:

  • Abantu abathathe iCopaxone banomyinge we-0.6 ukuya kwi-1.19 ye-MS ebuyela umva. Xa kuthelekiswa, abantu abathathe i-placebo (akukho siyobisi sisebenzayo) babenomndilili we-1.68 ukuya kwi-2.4 ye-MS kwakhona.
  • I-34% ukuya kwi-56% yabantu abathathe iCopaxone khange baphinde babuyele kwi-MS. Xa kuthelekiswa, i-27% ukuya kwi-28% yabantu abathathe indawo ye-placebo khange baphinde babuyele kwi-MS.

Ukongeza, olunye uphando lujonge kwisiphumo sokusebenzisa iCopaxone 20 mg yonke imihla kuphuhliso lwezilonda ezithile zobuchopho. Ezi zilonda, ezibonisa indawo zokudumba engqondweni, zachongwa kwizikena zeMRI. Ngaphezulu kweenyanga ezili-9 zonyango:

  • Isiqingatha sabantu abathathe iCopaxone baphuhlise izilonda ezitsha ezili-11
  • Isiqingatha sabantu abathathe indawo ye-placebo baphuhlise ubuncinci i-17 yezilonda ezintsha

Olunye uphononongo lujonge umphumo wokusebenzisa iCopaxone 40 mg kathathu ngeveki kubantu abane-MS. Ngaphezulu konyaka omnye wonyango, xa kuthelekiswa nabantu abasebenzisa i-placebo, abantu abasebenzisa iCopaxone:

  • 34% umngcipheko ophantsi wokubuyela umva kwe-MS
  • I-45% yomngcipheko ophantsi wezilonda zobuchopho ezibonakalise indawo ezivuthayo kwingqondo yabo
  • I-35% yomngcipheko ophantsi wokutsha okanye ukukhula kwezilonda zobuchopho ezibonakalise iindawo ezonakeleyo kwingqondo yabo

Ukusebenza kweCIS

Isifundo seklinikhi sijonge unyango lweCopaxone kubantu abaneCIS. Kolu phando, iCopaxone inciphise umngcipheko wabantu wokuba nesiqendu sesibini seempawu ezifana ne-MS.

Ngaphezulu kweminyaka emi-3 yonyango, abantu abathathe iCopaxone 20 mg yonke imihla babengaphantsi kwe-45% yokuba nesiqendu sesibini seempawu ezifana ne-MS kunabantu ababethathe indawo ye-placebo.

ICopaxone kunye nabantwana

ICopaxone ayivunyelwanga ukuba isetyenziswe kubantwana abaneminyaka eli-17 nangaphantsi. Nangona kunjalo, iyeza ngamanye amaxesha lisetyenziselwa ngaphandle kwelebheli ukunyanga i-MS ebantwaneni. (Ngokusetyenziswa kwelebheli engekho, iyeza elamkelweyo kwiimeko ezithile lisetyenziselwa ezinye iimeko.)

Olunye uphando lubonakalisile ukuba i-glatiramer (ichiza elisebenzayo kwiCopaxone) inokunciphisa inani lokuphinda ubuye kwi-MS ebantwaneni. Uphando lukwabonise ukuba iyeza layehlisa ukwanda kokukhubazeka okubangelwa yi-MS. Ukongeza, i-International Pediatric Multiple Sclerosis Study Group icebisa ukuba kusetyenziswe iCopaxone njengenye yeendlela zokuqala zonyango kubantwana abane-MS.

Ukuba unemibuzo malunga nokusebenzisa iCopaxone ukunyanga i-MS emntwaneni, thetha nogqirha wakho.

Ukuphelelwa lixesha kweCopaxone, ukugcinwa kunye nokulahlwa

Xa ufumana iCopaxone kwikhemesti yakho, umhla wokuphelelwa sisiyobisi uya kuprintwa kwibhokisi yesirinji, nakwisirinji ngokwazo. Umhla wokuphelelwa lixesha unceda ekuqinisekiseni ukuba amayeza ayasebenza ekusebenziseni ixesha elithile.

Isimo sangoku soLawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) kukuphepha ukusebenzisa amayeza aphelelwe lixesha. Ukuba awusebenzisanga iyeza elidlulileyo kumhla wokuphelelwa kwalo, thetha nosokhemesti wakho malunga nokuba unganako na ukuyisebenzisa.

Ukugcina

Ukuhlala ixesha elingakanani iyeza lihlala lilungile kunokuxhomekeka kwizinto ezininzi, kubandakanya ukuba uligcina phi kwaye phi na iyeza.

Isirinji ezalisiweyo zeCopaxone kufuneka zigcinwe kwifriji kubushushu obungu-36 ° F ukuya kuma-46 ° F (2 ° C ukuya ku-8 ° C). Musa ukumisa isikhenkcezo seCopaxone. Ukuba isirinji iba ngumkhenkce, ungayisebenzisi. Endaweni yoko, lahla isirinji kwisikhongozeli esibukhali.

Ukuba awukwazi ukuyifaka efrijini iCopaxone, njengaxa uhamba, ungaligcina ichiza kubushushu begumbi (59 ° F kuye kwi-86 ° F / 15 ° C ukuya kwi-30 ° C). Nangona kunjalo, unokugcina iCopaxone kuphela kubushushu begumbi ukuya kwinyanga enye. Kwaye ngelixa ichiza ligcinwa ngaphandle kwefriji, qiniseka ukuba iqondo lobushushu alinyuki ngaphezulu kwe-86 ° F (30 ° C).

Nokuba ugcina iCopaxone kwisibandisi okanye kubushushu begumbi, kuya kufuneka ugcine iisirinji kwiipakethi zazo zeblister, ngaphakathi kwebhokisi yabo yoqobo. Ukwenza oku kuya kukhusela iyeza ekukhanyeni.

Ukulahla

Kanye emva kokuba usebenzise isirinji, inaliti, okanye i-autoinjector, yilahle kwisikhongozeli esivunyiweyo sokulahla isixhobo esivunyiweyo se-FDA. Oku kunceda ukuthintela abanye, kubandakanya abantwana kunye nezilwanyana zasekhaya, ekubeni bathathe iyeza ngengozi okanye bazenzakalise ngenaliti. Ungathenga isikhongozeli esibukhali kwi-Intanethi, okanye ubuze ugqirha wakho, usokhemesti, okanye inkampani yeinshurensi yezempilo ukuba ungayifumana phi.

Eli nqaku libonelela ngamacebiso aluncedo ngokulahla amayeza. Unokucela ikhemesti yakho ukuba ikwazi ukuba ulahla njani na amayeza akho.

Imibuzo eqhelekileyo malunga neCopaxone

Nazi iimpendulo kwimibuzo ebuzwa rhoqo malunga neCopaxone.

Ngaba ndiza kuba neempawu zokurhoxa okanye iziphumo ebezingalindelekanga emva kokumisa iCopaxone?

Hayi, akunakulindeleka. Iimpawu zokurhoxa ziziphumo ebezingalindelekanga ezinokwenzeka xa uyeka ukuthatha iyeza umzimba wakho oxhomekeke kulo. (Ngokuxhomekeka, umzimba wakho ufuna ichiza ukuze uzive uqhelekile.)

Ukuyeka iCopaxone akwaziwa ukuba kunokubangela naziphi na iimpawu zokurhoxa. Ngenxa yoku, awudingi ukuyeka ukuthatha ichiza ngokuthe ngcembe, njengoko usenza ngamachiza athile anokubangela iimpawu zokurhoxa.

Nangona kunjalo, gcinani engqondweni ukuba ukumisa iCopaxone kunokubangela ukuba i-multiple sclerosis (MS) yakho iphinde iphinde iphinde ibe mandundu.

Ukuba unemibuzo malunga nokumisa iCopaxone, thetha nogqirha wakho. Banokuxoxa nawe ngomngcipheko kunye nezibonelelo zokuyeka eli chiza.

Ngaba ukusebenzisa iCopaxone kuyonyusa umngcipheko wam womhlaza?

Hayi Okwangoku kucingelwa ukuba akukho bungozi bonyukayo besifo somhlaza ngokusetyenziswa kweCopaxone. Ngelixa bekukho ezinye iingxelo zomhlaza kubantu abathatha iyeza emva kokuba likhutshiwe kwintengiso, ezi ngxelo bezinqabile. Kwaye ukwanda komngcipheko womhlaza khange kunxulunyaniswe ngqo nokusetyenziswa kweCopaxone.

Nangona kunjalo, ezinye iziyobisi ezisetyenziselwa ukunyanga i-multiple sclerosis (MS), ezinjengezo zibangela ukunyanzeliswa komzimba, kunokunyusa umngcipheko womhlaza. Imizekelo yezinye iziyobisi zibandakanya i-alemtuzumab (Lemtrada) kunye ne-mitoxantrone.

Ngokwesiqhelo, amajoni akho omzimba abulala iintsholongwane, kunye neeseli emzimbeni wakho ezingaqhelekanga okanye ezingasebenzi kakuhle. Eli nyathelo linceda ukukhusela ekukhuleni komhlaza kunye nosulelo. Kodwa ngoxinzelelo lwe-immunosuppression, amajoni akho omzimba ayacinezelwa (buthathaka) kwaye awusebenzi ngokufanelekileyo njengoko kufanelekile. Ukuba amajoni akho omzimba acinezelwe, unengozi enkulu yokuba nomhlaza kunye nosulelo.

ICopaxone yenza ukuba amanye amajoni omzimba wakho asebenze kancinci kunesiqhelo. Nangona kunjalo, iCopaxone ibizwa ngokuba yi-immunomodulator, kune-immunosuppressant. Kungenxa yokuba iCopaxone itshintsha indlela amajoni akho omzimba asebenza ngayo, endaweni yokucinezela amajoni akho omzimba.

Ukuba unemibuzo malunga nobungozi bonyango lweCopaxone, thetha nogqirha wakho.

Ngaba iCopaxone yi-biologic?

Hayi, iCopaxone ayiyiyo i-biologic. I-Biologics ngamachiza enziwe kwiiseli eziphilayo. ICopaxone yenziwa ngemichiza.

Ezinye zeendlela zokunyanga izifo ezisetyenziselwa ukunyanga i-multiple sclerosis (MS) zii-biologics, kodwa iCopaxone ayisiyiyo enye yazo. Imizekelo ye-biologics esetyenziselwa ukunyanga i-MS ibandakanya i-alemtuzumab (Lemtrada), natalizumab (Tysabri), kunye ne-ocrelizumab (Ocrevus).

Ngolwazi malunga nendlela iCopaxone esebenza ngayo ukunyanga i-MS, jonga kwicandelo "Isebenza njani iCopaxone" apha ngezantsi.

Ungathatha ixesha elingakanani iCopaxone?

ICopaxone yenzelwe ukuba isetyenziswe njengonyango lwexesha elide. Ngokubanzi, ungagcina ukuyithatha ixesha elide njengoko iqhubeka ikhuselekile kwaye isebenza kuwe.

Kodwa ukuba uba neziphumo ebezingalunganga okanye ezinzima, okanye ichiza aliyilawuli imeko yakho ngokwaneleyo, kungafuneka utshintshele kunyango olwahlukileyo. Kwimeko apho, ugqirha wakho uya kukucebisa ngolunye unyango.

Ukuba unemibuzo malunga nokuba uza kuthatha ixesha elingakanani iCopaxone, thetha nogqirha wakho.

Ndinganikela ngegazi xa ndithatha iCopaxone?

Ewe. Ngokwe-American Red Cross, ukuthatha iCopaxone akufuneki kukuthintele ekunikeni igazi. Kwaye kulungile ukunika igazi ukuba une-multiple sclerosis (MS), ukuba imeko yakho ilawulwa kakuhle kwaye okwangoku usempilweni.

Ukuba unemibuzo malunga nokuba kukhuselekile na kuwe ukunikela ngegazi, thetha nogqirha wakho. Okanye ungaqhagamshelana noMnqamlezo obomvu waseMelika ngokundwendwela iwebhusayithi yabo.

ICopaxone kunye nokukhulelwa

ICopaxone khange ifundwe kwabasetyhini abakhulelweyo. Ke ayaziwa ngokuqinisekileyo ukuba ichiza likhuselekile ukuthatha ngexesha lokukhulelwa.

Abanye abantu basetyhini bathathe iCopaxone ngexesha lokukhulelwa. Kodwa akukho lwazi lwaneleyo lufumanekayo lokuchaza ukuba ngaba ichiza liyabonyusa na ubungozi beziphene zokuzalwa okanye ukuphuphuma kwesisu.

Izifundo zezilwanyana zenziwe kubantu ababhinqileyo abakhulelweyo abanikwa iCopaxone. Kwaye ezi zifundo azibonisanga monakalo kwimveku xa kusetyenziswa ichiza. Kodwa gcinani engqondweni ukuba izifundo ezenziwe kwizilwanyana azihlali ziqikelela ukuba kuya kwenzeka ntoni ebantwini.

Ukuba ukhulelwe okanye unokukhulelwa, thetha nogqirha wakho malunga nokuba iCopaxone ikulungele na. Kwaye ukuba sele uthatha iCopaxone kwaye ukhulelwe, qiniseka ukubiza ugqirha wakho ngoko nangoko.

ICopaxone kunye nolawulo lokuzalwa

Ayaziwa ukuba iCopaxone ikhuselekile ukuthatha ngexesha lokukhulelwa. Ukuba usebenza ngokwesondo kwaye wena okanye iqabane lakho unokukhulelwa, thetha nogqirha wakho malunga neemfuno zakho zokulawula ukuzalwa ngelixa usebenzisa iCopaxone.

ICopaxone kunye nokuncancisa

Ayaziwa nokuba iCopaxone idlulela kubisi lwebele okanye ukuba inokuchaphazela umntwana oncancisayo.

Ukuba uncelisa okanye uceba ukuncelisa, xela ugqirha malunga nokuba iCopaxone ikulungele na.

ICopaxone kunye notywala

Utywala abaziwa ukunxibelelana neCopaxone. Nangona kunjalo, ukuba uneziphumo ebezingalindelekanga ezivela kwiCopaxone, njengokugungxula okanye isicaphucaphu, ukusela utywala kunokuzenza mandundu iziphumo zakho.

Emva kokuba iCopaxone ikhutshiwe kwintengiso, bekukho iingxelo zabantu abasebenzisa ichiza elinganyamezelaniyo notywala. (Ngokunyamezelana notywala, unokuba neempendulo ezithile emva nje kokuba usele utywala. Ezi mpendulo zinokubandakanya ukugungxula ebusweni bakho okanye impumlo exineneyo.)

Nangona kunjalo, ezi ngxelo zazinqabile. Kwaye ukunganyamezelani notywala akuzange kunxulunyaniswe ngqo nokusetyenziswa kweCopaxone.

Imingcipheko yokusetyenziswa kotywala kubantu abane-multiple sclerosis (MS) ayaziwa ngokuqinisekileyo. Ukuba usela utywala, thetha nogqirha wakho malunga nokuba kukhuseleke kangakanani ukuba ungatya.

Ukudibana kweCopaxone

Akukho nxibelelwano lwaziwayo phakathi kweCopaxone kunye nawaphi na amanye amayeza, amayeza, izongezo, okanye ukutya.

Nangona kunjalo, ngaphambi kokuba uthathe iCopaxone, thetha nogqirha wakho kunye nosokhemesti. Baxelele ngawo onke amayeza kagqirha, ekhawuntareni, kunye nezinye iziyobisi ozithathayo. Baxelele malunga nazo naziphi na iivithamini, amayeza esintu kunye nezixhasi ozisebenzisayo. Ukwabelana ngolu lwazi kunokukunceda uphephe unxibelelwano olunokubakho.

Ukuba unemibuzo malunga nokunxibelelana kweziyobisi okunokuchaphazela, buza ugqirha wakho okanye usokhemesti.

Isebenza njani iCopaxone

ICopaxone yamkelwe ukuze inyange iifom ezibuyayo ze-multiple sclerosis (MS) kunye nesifo esizimeleyo sonyango (CIS). (I-CIS yimeko ebangela iimpawu ezifana ne-MS.)

Kwenzeka ntoni kwi-MS?

I-MS yimeko yexesha elide eba mandundu ngokuhamba kwexesha. Ichaphazela inkqubo yakho ye-nervous system (CNS), eyenziwe ngengqondo yakho kunye nentambo yomgogodla. I-CNS yakho ikwenziwe yimithambo ethumela imiyalezo phakathi kwengqondo yakho kunye nomzimba wonke.

Nganye yezi ntsinga zemithambo-luvo ijikelezwe ngumaleko okhuselayo wethishu ebizwa ngokuba yi-myelin sheath. I-sheel sheath ifana nengubo yeplastiki ejikeleze iingcingo ngaphakathi kwentambo yombane. Ukuba isingxobo sonakele, imithambo-luvo yakho ayinakho ukuhambisa imiyalezo nayo.

Nge-MS, amajoni akho omzimba aqala ngempazamo ukuhlasela i-myelin sheaths ejikeleze imithambo-luvo yakho. Oku kubangela ukuvuvukala okonakalisa i-myelin sheaths. Umonakalo wenza kubenzima kwimithambo-luvo yakho ukuthumela nokufumana imiyalezo. Kuxhomekeka ekubeni yeyiphi na imithambo-luvo eyonakeleyo, iimpawu zakho ze-MS zinokwahluka kakhulu.

Emva kokuba amajoni akho omzimba ehlasele i-myelin sheath, izicwili ezibomvu zinokukhula zijikeleze iindawo ezonakeleyo. Izihlunu ezibomvu zenza ukuba kube nzima kwimithambo-luvo yakho ukuthumela nokufumana imiyalezo. Iindawo zomonakalo kunye nokonakala kwimithambo-luvo yakho zibizwa ngokuba zizilonda. Ezi ndawo zinokubonwa kwizikena ze-MRI, zovavanyo lokucinga olusetyenziselwa ukubeka esweni i-MS.

Yintoni ukubuyela kwakhona kwi-MS?

Ngokuphinda ubuye kwiifom ze-MS, uya kuba namaxesha apho iimpawu zakho ziba ngcono okanye kude kuphele. (La maxesha abizwa ngokuba kukuxolelwa.) Kodwa uya kuba namaxesha eempawu ezintsha ze-MS, okanye amaxesha xa iimpawu zakho ze-MS zibuya okanye zisiba mbi emva kokuba ziphuculwe. (La maxesha abizwa ngokuba abuyela umva.)

Uxolelo lwenzeka xa iiseli zakho zemithambo-luvo zizilungisa ngokwazo kumonakalo obangelwe yi-MS. Uxolelo lunokwenzeka kwakhona xa umzimba wakho usenza iindlela ezintsha zemithambo-luvo ezigqitha kwimithambo-luvo eyonakaliswe yi-MS. Amaxesha oxolelo anokuhlala kwiinyanga ezimbalwa ukuya kwiminyaka embalwa.

Isiqendu ngasinye somonakalo wemithambo-luvo kunye neempawu zaso ezinokubakho sinokuhlala iintsuku ezimbalwa okanye iinyanga ezimbalwa. Oku kubizwa ngokuba luhlaselo lwe-MS okanye ukuphinda ubuye kwi-MS. Ngokuhamba kwexesha, iimpawu zokubuyela umva kunokuba nzima okanye zibe rhoqo. Oku kukhula kukhokelela kubunzima kwimisebenzi yemihla ngemihla njengokuhamba okanye ukuthetha.

Yintoni iCIS?

Nge-CIS, unesiqendu esinye seempawu ezinjenge-MS ezihlala ubuncinci iiyure ezingama-24. I-CIS inakho okanye ayinakuqhubela phambili kwi-MS, kodwa inokuba luphawu lwe-MS enokwenzeka. Ngenxa yoku, ihlala iqokelelwa kunye nezinye iimeko, ezinje ngokubuyela kwakhona kwiifom ze-MS.

Wenza ntoni uCopaxone?

ICopaxone lonyango oluguqula isifo kwiifom ezibuyela umva ze-MS, kunye neCIS. Iyacotha ukonakalisa imithambo-luvo okubangelwa yi-MS kunye nokucutha ukuwohloka kwesi sifo.

ICopaxone iqulethe iziyobisi ze-acetate yeglatiramer esebenzayo. Yiprotein eyenziwe elebhu. Nangona kunjalo, ifana kakhulu nenye yeeproteni ezifumaneka ngokwendalo kwizicwili zomzimba wakho.

ICopaxone ibizwa ngokuba yi-immunomodulator. Isebenza ngokutshintsha umsebenzi weeseli ezithile kumajoni akho omzimba. Nangona kungaqondakali ngokupheleleyo ukuba ichiza lisebenza njani, kucingelwa ukuba lenza iiseli ezithile ezimhlophe zegazi, ezibizwa ngokuba yi-suppressor T iiseli. Ezi seli zisebenza ngeendlela ezininzi zokumisa amajoni akho omzimba ekuhlaseleni izicwili zakho ze-myelin sheath.

Ngokuhlaselwa okumbalwa kwi-myelin sheath yakho, kuya kufuneka uphinde ubuye umva nge-MS. Oku kunokucothisa ukuwohloka kwemeko yakho kunye nokwanda kokukhubazeka.

Kuthatha ixesha elingakanani ukusebenza?

ICopaxone izakuqala ukusebenza kwakamsinya emva kwenaliti yakho yokuqala, kodwa akunakufane uqaphele ukuba iyasebenza. Kungenxa yokuba iyeza linceda ukukhusela imeko yakho ukuba ibe mandundu, kunokuba unyange iimpawu zakho ezikhoyo.

Kodwa ngexesha lonyango, ugqirha wakho unokujonga ukuba iCopaxone isebenzela wena. Ukwenza oku, banoku-odola uvavanyo oluthile lokucinga, njengokuvavanywa kweMRI.

Iindleko zeCopaxone

Njengawo onke amayeza, indleko zeCopaxone zingahluka.

Ixabiso langempela oza kulihlawula lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

Isicwangciso sakho seinshurensi sinokufuna ukuba ufumane isigunyaziso ngaphambi kokuba uvume ukugubungela iCopaxone. Oku kuthetha ukuba ugqirha wakho kunye nenkampani yeinshurensi iya kudinga ukunxibelelana malunga nemiyalelo yakho phambi kokuba inkampani yeinshurensi iyigubungele iyeza. Inkampani yeinshurensi iyakusiphonononga isicelo kwaye ikuxelele wena nogqirha ukuba isicwangciso sakho siza kuyigubungela iCopaxone.

Ukuba awuqinisekanga ukuba uyakufuna ukufumana imvume kwangaphambili yeCopaxone, nxibelelana nenkampani yeinshurensi yakho.

Uncedo lwezezimali kunye neinshurensi

Ukuba ufuna inkxaso yemali ukuhlawulela iCopaxone, okanye ukuba ufuna uncedo lokuqonda i-inshurensi yakho, uncedo luyafumaneka.

I-Teva Neuroscience, Inc., umvelisi weCopaxone, ubonelela ngenkqubo ebizwa ngokuba ziSisombululo ekwabelwana ngaso. Le nkqubo ibonelela ngoncedo lwezezimali, kubandakanya nekhadi le-copay elinokunceda ukunciphisa iindleko zeCopaxone.

Ngolwazi oluthe kratya kunye nokufumanisa ukuba uyilungele na inkxaso, tsalela umnxeba ku-800-887-8100 okanye undwendwele iwebhusayithi yenkqubo.

Inguqulelo yesiqhelo

I-Copaxone ifumaneka ngohlobo oluqhelekileyo olubizwa ngokuba yi-glatiramer acetate. Ichiza elenza lafana nelo lenziwe ngumenzi liyikopi ngqo yesiyobisi esisebenzayo kumayeza anegama lophawu. Igeneric ithathwa ngokuba ikhuselekile kwaye iyasebenza njengesiyobisi sokuqala. Kwaye ii-generics zihlala zibiza ixabiso elingaphantsi kwelesiyobisi.

Ukufumanisa ukuba indleko zeglatiramer acetate ngokuthelekiswa neendleko zeCopaxone, ndwendwela iGoodRx.com. Kwakhona, iindleko ozifumanayo kwi-GoodRx.com yinto onokuyihlawula ngaphandle kwe-inshurensi. Ixabiso langempela oza kulihlawula lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

Ukuba ugqirha wakho umisele iCopaxone kwaye unomdla wokusebenzisa i-acrylic glatiramer acetate endaweni yoko, thetha nogqirha wakho. Banokukhetha uhlobo olunye okanye olunye. Kuya kufuneka ujonge isicwangciso sakho seinshurensi, njengoko inokugubungela enye okanye enye.

Izilumkiso zeCopaxone

Ngaphambi kokuba uthathe iCopaxone, thetha nogqirha wakho malunga nembali yakho yezempilo. ICopaxone isenokungakulungeli ukuba uneemeko ezithile zonyango okanye ezinye izinto ezichaphazela impilo yakho. Oku kubandakanya:

  • Ukungezwani komzimba neCopaxone. Sukuyithatha iCopaxone ukuba wakha wadibana neCopaxone, glatiramer acetate (ichiza elisebenzayo eCopaxone), okanye i-mannitol (into engasebenziyo eCopaxone). Ukuba awuqinisekanga malunga neyeza lakho lokunyanga, thetha nogqirha wakho.
  • Ukukhulelwa. Ayaziwa ukuba iCopaxone ikhuselekile ukuyisebenzisa ngexesha lokukhulelwa. Ngolwazi oluthe kratya, nceda ubone icandelo "Copaxone kunye nokukhulelwa" apha ngasentla.
  • Ukuncancisa. Ayaziwa ukuba iCopaxone idlula kubisi lwebele. Ngolwazi oluthe kratya, nceda ubone icandelo "Copaxone kunye nokuncancisa" apha ngasentla.

Phawula: Ngolwazi oluthe kratya malunga neziphumo ezinokubakho zeCopaxone, jonga icandelo leCopaxone elingentla.

Ukudlula ngaphezulu kweCopaxone

Sukusebenzisa ngaphezulu kweCopaxone kunokuba ugqirha ekucebisa. Kwamanye amachiza, ukwenza njalo kungakhokelela kwiziphumo ebezingalindelekanga ezingafunekiyo okanye kwiidosi.

Kufuneka wenze ntoni xa uthe wathatha iCopaxone kakhulu

Ukuba ucinga ukuba uthathe kakhulu eli chiza, tsalela ugqirha wakho. Ungabiza uMbutho waseMelika wamaZiko oLawulo lweTyhefu ku-800-222-1222 okanye usebenzise isixhobo esikwi-Intanethi. Kodwa ukuba iimpawu zakho zinzima, tsalela umnxeba ku-911 okanye uye kwigumbi likaxakeka elikufutshane ngoko nangoko.

Ulwazi lobungcali lweCopaxone

Olu lwazi lulandelayo lubonelelwe ngoochwephesha kunye nabanye abaqeqeshi bezempilo.

Iimpawu

ICopaxone yamkelwe ukunyanga le miqathango kubantu abadala:

  • Isifo esizimele sodwa (CIS)
  • Ukubuyela kwakhona kwi-MS (RRMS)
  • i-MS esebenzayo (i-SPMS) yesibini esebenzayo

Indlela yokusebenza

ICopaxone lonyango oluguqula isifo oluqulethe ichiza elisebenzayo le-glatiramer acetate. Sisiyobisi esichaphazela ukungahambi kakuhle, nangona indlela yokusebenza kwayo ingaqondwa kakuhle.

I-acetate yeGlatiramer yimolekyuli yokwenziwa kweproteni efanayo kwenye yeeproteni zendalo ezifumaneka kwi-myelin. Kubonakala ngathi kusebenze iiseli zokucinezelwa kwe-T ezithintela impendulo yomzimba kwi-myelin.

I-Glatiramer ngokwenjenje iyanciphisa uhlaselo lomzimba kwi-myelin, ikhokelela ekubeni zombini i-MS iphinde ibuye kwaye icothise ukuqhubela phambili kwesi sifo.

I-Pharmacokinetics kunye ne-metabolism

Inani elibalulekileyo leCopaxone li-hydrolyzed in a subcutaneous tissue emva kolawulo. Zombini i-Copaxone ehambelanayo kunye ne-hydrolyzed ingena kwi-lymphatic kunye ne-systemic circulation. Isiqingatha sobomi beCopaxone asaziwa.

Ukungqinelana

I-Copaxone akufuneki isetyenziswe kubantu abanokwaliwa komzimba kwi-glatiramer acetate okanye kwi-mannitol.

Ukugcina

Gcina iCopaxone kwifriji kubushushu obungu-36 ° F ukuya kuma-46 ° F (2 ° C ukuya ku-8 ° C). Gcina iyeza kwiipakethe zokuqala. Musa ukubanda. Ukuba isirinji yeCopaxone sele iqabile, ungayisebenzisi.

Ukuba iyafuneka, iCopaxone inokugcinwa kubushushu begumbi (i-59 ° F ukuya kwi-86 ° F / 15 ° C ukuya kwi-30 ° C) ukuya kuthi ga kwinyanga enye.

Iphepha elichazayo ukuba awusenanto oyifunayo: Iindaba zezoNyango namhlanje zenze zonke iinzame zokuqinisekisa ukuba zonke iinkcukacha zichanekile, zibanzi kwaye zihlaziyiwe. Nangona kunjalo, eli nqaku akufuneki lisetyenziswe endaweni yolwazi kunye nobuchule bengcali yezempilo enelayisensi. Kuya kufuneka usoloko uqhagamshelana nogqirha wakho okanye nolunye uqeqesho kwezonyango ngaphambi kokuba uthathe nawaphi na amayeza. Ulwazi lweziyobisi oluqulethwe apha luyakwazi ukutshintsha kwaye alujoliswanga ekusetyenzisweni konke okunokwenzeka, imikhombandlela, izilumkiso, izilumkiso, ukuhlangana kweziyobisi, ukungahambelani komzimba, okanye iziphumo ezibi. Ukungabikho kwezilumkiso okanye olunye ulwazi ngesiyobisi esinikiweyo akubonisi ukuba indibaniselwano yeziyobisi ikhuselekile, iyasebenza, okanye ifanelekile kuzo zonke izigulana okanye konke ukusetyenziswa okuthile.

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