Wazi njani ukuba uneGout kwiGxalaba lakho- kunye nento ekufuneka uyenze ngokulandelayo

Umxholo

• Iinyani ezikhawulezayo malunga negawuthi
• Iimpawu zesifo segout egxalabeni lakho
• Izinto ezibangela igawuthi egxalabeni lakho
• Ukuveliswa kakhulu kweuric acid
• Ezinye izinto
• Imiba yomngcipheko wegout egxalabeni lakho
• Isini
• Ubudala
• Imfuza
• Iimeko zonyango
• Indlela yokuphila
• Uxilongo sifo sifo egxalabeni lakho
• Unyango lwe-gout egxalabeni lakho
• Amayeza aqhelekileyo
• Ezinye iziyobisi
• Olunye unyango
• Ubude be-gout flare-up
• Iingxaki ze-gout egxalabeni lakho
• Ukuthintela igawuthi
• Ezinye iimeko ezibangela iintlungu zamagxa kunye nokudumba
• I-Pseudogout
• Imbonakalo

Igawuthi luhlobo oluqhelekileyo lwesifo samathambo. Kukudumba okungxamisekileyo kwaye okubuhlungu okuhlala kwenzeka kwizinzwane ezinkulu, kodwa kunokuchaphazela amanye amalungu. Kusemagxeni nasezinqeni.

Ukudumba kubangelwa kukukhula kweekristali ezincinci ze-uric acid kumalungu akho. Amajoni akho omzimba ayasabela ngokuthumela iiseli ezilwa nosulelo kuloo ndawo, zibangele ukudumba.

Uhlaselo lweGout ludla ngokuhamba kancinci kwaye lunokuchaphazela ngaphezulu kwelinye ngokudibeneyo. Igawuthi ihlala ilawulwa ngokutya nangamayeza. Xa kunyangwa igawuthi, iingxaki zinqabile. Kodwa igawuthi enganyangekiyo inokukhubaza.

Kukho ukuba abanye abantu banomdla wemfuza kwi-gout.

Iinyani ezikhawulezayo malunga negawuthi

• Inkcazo yegawuthi ibuyela emva phantse kwiminyaka engama-5 000 ukuya kwi-Egypt yamandulo. Kuthathwa njengeyona nto iqondwa kakuhle sisifo samathambo.
• Malunga noluntu lwehlabathi lune gout.
• Iipesenti ezine zabantu eUnited States banegawuthi.
• Iziganeko ze-gout bezikhula kwiminyaka yakutshanje kumazwe ahambele phambili.
• Igama livela kwigama lesiLatini elithi "gutta," elithetha ukuhla. Ibhekisa kwinkolo yamaxesha aphakathi yokuba enye yezo "humor" zifunekayo kwimpilo "yehle" kwilungu.
• I-Gout yayibizwa ngokuba sisifo sookumkani, ngenxa yokuhlangana kwayo nokutya okunotye kunye nokusela utywala.
• UBenjamin Franklin no-Thomas Jefferson bobabini babene gout.

Iimpawu zesifo segout egxalabeni lakho

Uhlaselo gout ludla ngokufika ngesiquphe. Ubuhlungu begxalaba bakho mhlawumbi bunzima okanye buhlungu.

Ukongeza, indawo inokuba:

• bomvu
• ukudumba
• ziqinile
• kushushu okanye kuyatsha
• uvakalelo kakhulu ekuchukumiseni nasekuhambeni

Izinto ezibangela igawuthi egxalabeni lakho

Ukugqitha kwe-uric acid egazini lakho kucingelwa ukuba kungadala igout ngokwenza iikristali ezimilise inaliti ezakha kwizicwili nakumalungu akho. Uric acid egqithileyo yaziwa njenge-hyperuricemia.

I-acid yeUric yimveliso yenkunkuma eveliswa kukwaphuka kweepurines, iikhompawundi zemichiza zendalo ezikhoyo emzimbeni wakho. IUric acid ikwaveliswa xa usetyisa ukutya okuqukethe iipurine.

Ngokwesiqhelo izintso zakho zisusa inkunkuma ye-uric acid ngomchamo wakho. Ukuba izintso zakho azisebenzi kakuhle, amanqanaba e-uric acid anokwakha kwigazi lakho.

Amakristali avela kule uric acid ingaphaya ahlaselwa ngumzimba wakho njengamaqumrhu angaphandle. Iiseli ezilwa nosulelo ziya kwindawo yeekristali, zibangele ukudumba.

Ingxelo yegawuthi yeepesenti ezili-10 kuphela zamatyala zibangelwa kukunyuka komzimba kwimveliso yeuric acid. Ezinye iipesenti ezingama-90 zibangelwa kukusilela kwezintso ekupheliseni uric acid owaneleyo.

Ukuveliswa kakhulu kweuric acid

Ukutya izixa ezigqithileyo zeemveliso eziqukethe i-purines kunokuba negalelo kumanqanaba agqithisileyo e-uric acid kwabanye abantu. Iimveliso eziphezulu kwiipurine zibandakanya:

• inyama ebomvu
• ukutya kwaselwandle
• intlanzi
• ibhiya
• iimbotyi ezomileyo

Utywala, ngakumbi utywala obunobungqina obuphezulu, bukwakhuthaza imveliso kunye nokugcinwa kwe-uric acid. Kodwa ukusela iwayini ngexabiso eliphakathi akunxulunyaniswa negawuthi.

Ezinye izinto

Kuphela malunga namanqanaba aphezulu e-uric acid egazini labo aphuhlisa igawuthi. Eminye imiba enokuthi ibandakanyeke kuphuhliso lwegawuthi ibandakanya:

• imeko yemfuza
• ukuphazamiseka kwegazi
• Iicancer ezinjengeleukemia
• incindi encinci ye-synovial fluid kumalungu
• Ubumdaka bolwelo oludibeneyo
• ukutya okuphezulu kwi-purines
• ukulimala ngokudibeneyo, usulelo, okanye utyando
• iimeko zokungena kweseli eziphezulu njengepsoriasis

Amanye amayeza anokunyusa amanqanaba e-uric acid egazini. Oku kubandakanya:

• i-diuretics, esetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu okanye isifo sentliziyo
• amathamo asezantsi easprini
• cyclosporine, sisiyobisi esithintela amajoni omzimba
• i-levodopa, ichiza elisetyenziselwa ukunyanga i-Parkinson

Imiba yomngcipheko wegout egxalabeni lakho

Nayiphi na into eyonyusa amanqanaba e-uric acid egazini lakho inokukubeka emngciphekweni wokuhlaselwa yintsholongwane. Ezinye zezinto ezinobungozi zezi:

Isini

Igawuthi imalunga nokuxhaphaka emadodeni.

Ubudala

Igawuthi idla ngokwenzeka kumadoda angaphezu kwama-40 nakumabhinqa emva kokuyeka ukuya exesheni. Ku, ukuxhaphaka kwegawuthi kumalunga neepesenti ezili-10 zamadoda kunye neepesenti ezi-6 zabasetyhini.

Imfuza

Ukuba namanye amalungu osapho ane-gout kwandisa umngcipheko. Imfuza ethile ichongiwe enxulunyaniswa nokukwazi kwezintso ukususa i-uric acid.

Iimeko zonyango

Iimeko zonyango ezichaphazela ukusebenza kwezintso zikubeka emngciphekweni wokuhlaselwa yintsholongwane. Ukuba utyandwa okanye wenzakele, oku kunganyusa umngcipheko.

Abantu abaninzi abane-gout banazo nezinye iimeko zonyango. Nokuba igawuthi ibangela le meko okanye yonyusa umngcipheko kwezi meko ayicacanga.

Ezinye zeemeko zonyango ezonyusa umngcipheko we-gout, ngakumbi ukuba azinyangwa, zibandakanya:

• igazi elonyukayo
• isifo seswekile
• isifo sezintso
• ezinye iintlobo ze-anemia
• isifo metabolic
• ukuthintela ukuphefumla xa ulala
• Psoriasis
• kukhokelela kwityhefu

Indlela yokuphila

Ukutyeba kakhulu okanye ukutyeba kakhulu kwandisa umngcipheko we-gout. Ubunzima obongezelelekileyo bonyusa imveliso yakho ye-uric acid.

Ukutya ukutya okweqile kunye nokusela okuphezulu kwi-purines kunokunyusa umngcipheko we-gout. Abo batya ukutya okusekwe kwirayisi kunye nemifuno kunye neepurine ezisezantsi baneziganeko ezisezantsi zegawuthi.

Uxilongo sifo sifo egxalabeni lakho

Ugqirha wakho uya kukuvavanya, athathe imbali yonyango, kwaye abuze malunga neempawu zakho. Banokukwazi ukubona i-gout esekwe kwiimpawu zakho.

Kodwa ugqirha uya kufuna ukulawula ezinye izizathu ezinokubangela iintlungu zakho ngokuyalela iimvavanyo.

Ukujonga iimvavanyo kwigxalaba lakho kubandakanya i-X-ray, i-ultrasound, kunye ne-MRI scan.

Ugqirha uya kuvavanya amanqanaba egazi e-uric acid. Kodwa amanqanaba aphezulu okanye i-uric acid ayonelanga ukwenza ukuxilongwa okuqinisekileyo.

Uvavanyo oluthe kratya kukuthatha isampulu yamagxa akho edibeneyo ye-synovial fluid usebenzisa inaliti encinci kakhulu. Oku kubizwa ngokuba yi-arthrocentesis okanye umnqweno odibeneyo. Ilabhoratri iya kuthi emva koko ijonge i-uric acid crystals phantsi kwemicroscope.

Ugqirha wakho angakuthumela kwi-rheumatologist yonyango oluqhubekayo.

Unyango lwe-gout egxalabeni lakho

Akukho lunyango lwesifo segawuthi, kodwa amayeza amaninzi aphuhlisiwe kwiminyaka yakutshanje anokunceda kwintlungu yegxalaba lokuqaqanjelwa nokuthintela ukutsha kwexesha elizayo.

Amayeza ajolise ekunciphiseni iintlungu, ukunciphisa amanqanaba akho e-uric acid, kunye nokunciphisa ukudumba.

Amayeza aqhelekileyo

Ugqirha wakho unokucebisa ngaphezulu kwe-counter-counter-anti-inflammatory drugs (i-NSAIDs) kwiintlungu okanye kumachiza amayeza anciphisa ukuvuvukala.

Amachiza amiselweyo abandakanya i-indomethacin (Indocin) okanye i-celecoxib (iCelebrex), kunye ne-prednisone, i-corticosteroid. I-Prednisone ihlala itofelwe kwilungu elichaphazelekayo, kodwa i-prednisone yomlomo isenokufuneka xa amalungu amaninzi ebandakanyeka.

Kuxhomekeka kubukhali beempawu zakho, ugqirha wakho unokukunika amanye amachiza:

• Ukuthintela iiseli ezimhlophe zegazi ekuhlaseleni iikristali ze-uric acid, ezinje ngecolchicine (Colcrys)
• ukunciphisa inani lemveliso ye-uric acid, njenge-allopurinol (iZyloprim) kunye ne-febuxostat (Uloric), ebizwa ngokuba yi-xanthine oxidase inhibitors
• ncedisa izintso zakho ukususa i-uric acid engaphezulu, njengeprobenecid (Probalan) kunye ne-lesinurad (Zurampic), ebizwa ngokuba yi-uricosurics

Zonke ezi ziyobisi zineziphumo ebezingalindelekanga, kwaye ezinye zinokunxibelelana namanye amayeza okanye zenze mandundu ezinye iimeko onokuba nazo. Qiniseka ukuba uyaxoxa ngesicwangciso sakho sonyango lweziyobisi kunye nogqirha wakho.

Ezinye iziyobisi

kwaye unokufumana uvavanyo lwezonyango.

Ugqirha wakho unokufuna ukuzama ukusebenzisa iyeza elitsha "ngaphandle kwelebula," okanye ngenjongo engavunyelwanga okwangoku.

Ukuba iyeza livunyiwe kwi-rheumatoid arthritis okanye enye imeko kwaye ayikavunyelwa i-gout, ugqirha wakho unokuyincoma ngaphandle kwelebula.

Amanye ala machiza amatsha ngala:

• i-pegloticase (Krystexxa), ecutha i-uric acid kwaye yamkelwe e-United States kunyango lwe-gout enganyangekiyo enganyangekiyo.
• I-canakinumab, i-monoclonal antibody ethintela ukudumba
• anakinra, i-interleukin-1 beta antagonist ethintela ukudumba

Kuya kufuneka ukuba ukhangele umboneleli wakho weinshurensi malunga nala mayeza xa usetyenziswa ngaphandle kwelebheli.

Olunye unyango

Ubungqina obunxulumene notshintsho kwindlela yokutya abuhambelani, ngokweAmerican College of Physicians ye-gout ngo-2017.

Izifundo zibonise ukuba kuncitshisiwe ukutya inyama ebomvu, iswekile, kunye notywala kunciphise amanqanaba euric acid. Kodwa bekungacacanga ukuba oku kuphucule iziphumo ezibonakalayo.

Unokufumana isiqabu kolunye unyango lokudumba, njengomkhenkce kunye nonyango lomzimba.

Ubude be-gout flare-up

Ukuvutha kwegawuthi kuhlala kuhleli. Umzimba ucima impendulo yokuvuvukala emva kwexesha.

Unokuba namava okuphindayo kwiinyanga ezintandathu ukuya kwiminyaka emibini, okanye nangaliphi na ixesha kwixesha elizayo ukuba imeko yakho yomngcipheko ayitshintshi. Igawuthi inokuba sisifo esinganyangekiyo, ngakumbi ukuba uqhubeka nokuba nenqanaba eliphezulu leuric acid.

Igawuthi isenokusasazeka ibandakanye amanye amalungu. Igawuthi yamagxa inokwenzeka kubantu abane-gout ende.

Ugqirha wakho unokumisela amanqanaba asezantsi amachiza ngokuqhubekayo ukunceda ukuthintela ukuqhuma kwexesha elizayo kunye neengxaki ezinokubakho, kunye nokuthoba amanqanaba e-uric acid serum. Kubalulekile ukunamathela kwisicwangciso sakho sonyango ukunciphisa i-flares.

Iingxaki ze-gout egxalabeni lakho

Abantu abane-gout yexesha elide banokuphuhlisa iingxaki. Iikristale zeUric acid ngokuhamba kwexesha zinokonakalisa igxalaba okanye amanye amalungu.

Phantse iipesenti ezili-15 zabantu abane-gout bahlakulela amatye ezintso njengoko i-uric acid iqokelela kwizintso.

Enye ingxaki yesifo esinganyangekiyo kukwakheka kwamaqhuqhuva euric acid kwithishu yakho ethambileyo, ngakumbi iminwe neenzwane. I-nodule ibizwa ngokuba yitophus.

Ezi maqhuqhuva azidli ngokuba buhlungu, kodwa zinokudumba, zosuleleke, okanye zibe ne-oozy. Ezi maqhuqhuva zinokunyibilika ngonyango olufanelekileyo.

Ukuthintela igawuthi

Amanyathelo othintelo lwe-Gout abandakanya le ndlela yokuphila ilandelayo:

• ukutya ukutya okusempilweni, kubandakanya ukutya okuncinci kunye nokusela okulinganiselweyo okanye okuninzi okunepurine eninzi
• ukugcina ubunzima obunempilo
• ukuzilolonga rhoqo
• ukusela amanzi amaninzi
• ukuyeka ukutshaya

Unokufuna ukugcina umkhondo wento ebonakala ngathi ibangela ukuvutha kwegxalaba lakho ukuze uthintele ii-flares ezizayo.

Ezinye iimeko ezibangela iintlungu zamagxa kunye nokudumba

Ukuba unentlungu kunye nokuvuvukala, kungcono ukubona ugqirha wakho ukuxilongwa ngokuqinisekileyo kunye nonyango. Kukho iimvavanyo ezithile ezinokuthi zichonge igawuthi.

Ezinye zeemeko ezinokuba neempawu ezifanayo zibandakanya:

• bursitis
• tendinitis
• iinyembezi zemisipha
• osteoarthritis

I-Pseudogout

Kukho uhlobo lwesifo samathambo esaziwa njenge-pseudogout, esichaphazela ikakhulu abantu abadala. I-pseudogout ibangela ukudumba okubuhlungu ngesiquphe kumalungu, kodwa iikristali zeuric acid azibandakanyeki. I-Pseudogout ibangelwa kukuqokelelwa kweekristal pyrophosphate dihydrate.

Uhlalutyo lweekristal kwi-synovial fluid yakho inokumisela ukuba ngaba igxalaba lakho lokudumba lipseudogout okanye igxalaba.

Imbonakalo

Igawuthi egxalabeni yimeko enqabileyo, kodwa unyango kunye nembonakalo ziyafana ne-gout kwamanye amalungu. Ngazo zonke iintlobo ze-gout, ukunamathela kunyango lwakho kunye nesicwangciso sonyango kuya kukunika iziphumo ezingcono.

Kubalulekile ukuba ubone ugqirha ukuba unamagxa kunye nokudumba. Ukuba yi-gout, unyango luya kukunceda ulawule imeko kwaye uncede ukuthintela ii-flares ezizayo. Ugqirha wakho unokukucebisa malunga nonyango olutsha phantsi kophuhliso.

Unokufuna ukunxibelelana neAlliance for Gout Awareness okanye iArthritis Foundation ukugcina uphuhliso olutsha kunyango lwe-gout.