IHemoglobin Electrophoresis

Umxholo

• Yintoni ihemoglobin electrophoresis?
• Isetyenziselwa ntoni?
• Kutheni ndifuna ihemoglobin electrophoresis?
• Kwenzeka ntoni ngexesha le-hemoglobin electrophoresis?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kwi-hemoglobin electrophoresis?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga nehemoglobin electrophoresis?
• Izalathiso

Yintoni ihemoglobin electrophoresis?

IHemoglobin yiprotein ekwiiseli ezibomvu zegazi ezithwala ioksijini kwimiphunga yakho iye kumzimba wakho uphela. Kukho iintlobo ezahlukeneyo zehemoglobin. Ihemoglobin electrophoresis luvavanyo olulinganisa iintlobo ezahlukeneyo zehemoglobin egazini. Ikwajonga kwakhona iintlobo ezingaqhelekanga zehemoglobin.

Iindidi eziqhelekileyo zehemoglobin zibandakanya:

• IHemoglobin (Hgb) A, lolona hlobo luqhelekileyo lwehemoglobin kubantu abadala abasempilweni
• IHemoglobin (Hgb) F, ihemoglobin yomntwana. Olu hlobo lwehemoglobin lufumaneka kwiintsana ezingekazalwa nakwiintsana. I-HgbF ithathelwa indawo yi-HgbA kungekudala emva kokuzalwa.

Ukuba amanqanaba e-HgbA okanye i-HgbF aphezulu kakhulu okanye asezantsi kakhulu, inokubonisa iintlobo ezithile ze-anemia.

Iindidi ezingaqhelekanga zehemoglobin zibandakanya:

• IHemoglobin (Hgb) S. Olu hlobo lwe-hemoglobin lufumaneka kwisifo se-sickle cell. Isifo seSickle cell sisifo esasizuz 'ilifa esenza ukuba umzimba wenze iiseli ezibomvu ezingqindilili, ezimile okwegwebu. Iiseli ezibomvu ezisempilweni ziyaguquguquka ukuze zihambe ngokulula kwimithambo yegazi. Iiseli ezigulayo zinokuxinana kwimithambo yegazi, zibangele iintlungu eziqatha nezingapheliyo, usulelo kunye nezinye iingxaki.
• IHemoglobin (Hgb) C. Olu hlobo lwehemoglobin aluthwali ioksijini kakuhle. Ingabangela uhlobo olungephi lwe-anemia.
• IHemoglobin (Hgb) E. Olu hlobo lwehemoglobin lufunyanwa ikakhulu kubantu abavela kumazantsi mpuma eAsia. Abantu abane-HgbE bahlala bengenazo iimpawu okanye iimpawu ezibuthathaka ze-anemia.

Uvavanyo lwe-hemoglobin electrophoresis lusebenzisa umbane kwisampulu yegazi. Oku kwahlula iindidi eziqhelekileyo zehemoglobin. Uhlobo ngalunye lwehemoglobin lunokulinganiswa ngokwahlukeneyo.

Amanye amagama: Hb electrophoresis, uvavanyo lwehemoglobin, hemoglobinopathy, iqhekeza lehemoglobin, Hb ELP, iselfowuni

Isetyenziselwa ntoni?

Ihemoglobin electrophoresis imilinganiselo yehemoglobin kwaye ijonge iintlobo ezingaqhelekanga zehemoglobin. Ihlala isetyenziswa ukunceda ukufumanisa isifo se-anemia, isifo se-sickle cell, kunye nezinye iingxaki ze-hemoglobin.

Kutheni ndifuna ihemoglobin electrophoresis?

Unokufuna uvavanyo ukuba uneempawu zesifo sehemoglobin. Oku kubandakanya:

• Ukudinwa
• Ulusu oluthuthu
• IJaundice, imeko ebangela ukuba ulusu namehlo akho ajike abe tyheli
• Intlungu ebuhlungu (isifo serhengqa)
• Iingxaki zokukhula (ebantwaneni)

Ukuba usandul 'ukufumana umntwana, usana lwakho olusandul' ukuzalwa luya kuvavanywa njengenxalenye yovavanyo olusandul 'ukuzalwa. Uvavanyo olusandul 'ukuzalwa liqela leemvavanyo ezinikwa uninzi lweentsana zaseMelika emva nje kokuzalwa. Ukuhlolwa kokuhlolwa kweemeko ezahlukeneyo. Uninzi lwezi meko lunokunyangwa ukuba lufunyenwe kwangethuba.

Unokufuna nokuvavanywa ukuba usemngciphekweni wokuba nomntwana onesifo se-sickle cell okanye esinye isifo se-hemoglobin. Izinto zomngcipheko zibandakanya:

• Imbali yosapho
• Imvelaphi yobuhlanga
  • E-United States, uninzi lwabantu abanesifo se-sickle cell ngoo-Afrika.
  • I-Thalassemia, enye ingxaki ye-hemoglobin eyifa, ixhaphake kakhulu phakathi kwabantu base-Italiya, amaGrike, amaMpuma Mpuma, amaZantsi eAsia, kunye neAfrika.

Kwenzeka ntoni ngexesha le-hemoglobin electrophoresis?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ukuvavanya usana olusandul 'ukuzalwa, umboneleli wezempilo uyakucoca isithende somntwana wakho ngotywala kwaye asibambe isithende ngenaliti encinci. Umboneleli uya kuqokelela amathontsi ambalwa egazi kwaye abeke i-bandage kwisiza.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-hemoglobin electrophoresis.

Ngaba bukhona ubungozi kwi-hemoglobin electrophoresis?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Usana lwakho lunokuziva lincinci kancinci xa isithende sikhutshiwe, kwaye ukubetha okuncinci kunokubakho kwindawo leyo. Oku kuya kuhamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Iziphumo zakho ziya kubonisa iintlobo zehemoglobin ezifumanekayo kunye namanqanaba nganye.

Amanqanaba e-hemoglobin aphezulu kakhulu okanye aphantsi kakhulu kunokuthetha:

• I-Thalassemia, imeko echaphazela ukuveliswa kwehemoglobin. Iimpawu ziqala ukusuka kubumnene ukuya kubunzima.
• Uphawu lweseli lokugula. Kule meko, unegciwane elinye leseli yemfuza kunye nohlobo olunye oluqhelekileyo. Uninzi lwabantu abaneempawu zeseli zerhengqa abanangxaki zempilo.
• Isifo seSickle cell
• Isifo seHemoglobin C, imeko ebangela uhlobo olungephi lwe-anemia kwaye ngamanye amaxesha ukwanda kwepleen kunye nentlungu edibeneyo
• Isifo seHemoglobin SC, imeko ebangela uhlobo oluthambileyo okanye olulinganiselweyo lwesifo serhengqa

Iziphumo zakho zinokubonisa ukuba ingxaki ethile iphakathi, imodareyitha, okanye ibukhali.

Iziphumo zovavanyo lwe-Hemoglobin electrophoresis zihlala zithelekiswa nolunye uvavanyo, kubandakanya ukubala okupheleleyo kwegazi kunye ne-smear yegazi. Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga nehemoglobin electrophoresis?

Ukuba usemngciphekweni wokuba nomntwana onesifo esine-hemoglobin, ungafuna ukuthetha nomcebisi ngemfuzo. Umcebisi ngemfuzo yingcali eqeqeshwe ngokukodwa kwimfuzo novavanyo lwemfuzo. Unokukunceda uqonde ingxaki kunye nomngcipheko wokuyidlulisela emntwaneni wakho.

Izalathiso

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2. Iklinikhi yaseCleveland [kwi-Intanethi]. Cleveland (OH): Iiklinikhi yaseCleveland; c2020. I-Sickle Cell Anemia: Ubume; [icatshulwe ngo-2020 uJan 10]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia
3. Impilo yaBantwana kwiNemours [kwi-Intanethi]. UJacksonville (FL): Isiseko seNemours; c1995-2020. Uvavanyo lwegazi: IHemoglobin Electrophoresis; [icatshulwe ngo-2020 uJan 10]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://kidshealth.org/en/parents/test-electrophoresis.html
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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.