IKadcyla
Umxholo
- Iimpawu Kadcyla
- Ixabiso leKadcyla
- Uyisebenzisa kanjani iKadcyla
- Iziphumo ebezingalindelekanga zeKadcyla
- Ukungqinelana kweKadcyla
IKadcyla sisiyobisi esiboniswe kunyango lomhlaza wamabele onamatye amaninzi emzimbeni. Eli yeza lisebenza ngokuthintela ukukhula kunye nokwakheka kweeseli zomhlaza zesifo somhlaza.
IKadcyla liyeza eliveliswa yinkampani eyenza amayeza iRoche.
Iimpawu Kadcyla
I-Kadcyla ibonakalisiwe kunyango lomhlaza webele osele ukwinqanaba eliphambili kwaye sele isasazekile kwamanye amalungu omzimba. Ihlala inikwa isigulana emva kokuba kunikwe ezinye iziyobisi zomhlaza kwaye zingaphumeleli.
Iyeza iKadcyla lenziwe ngamachiza amabini, i-trastuzumab ethintela ukukhula kweeseli zomhlaza kunye ne-mertansine engena kwiiseli iyitshabalalise, ukunciphisa ithumba kunye nokuqhubeka kwesi sifo, kunye nokwandisa ubomi besigulana.
Ixabiso leKadcyla
Ixabiso leKadcyla ngenyanga liyi- $ 9800, kunye nezifundo zeenyanga eziyi-9.6 zonyango ezibiza i- $ 94,000.
Uyisebenzisa kanjani iKadcyla
Idosi ekhuthazwayo yeKadcyla yi-3.6 mg / kg kwaye ilawulwa ngenaliti efakwa ngaphakathi rhoqo kwiiveki ezi-3.
Kunyango lokuqala, ichiza kufuneka lilawulwe kangangemizuzu engama-90, kunye nezigulana ezijongiweyo ukujonga ukubonakala kweziphumo ebezingalindelekanga. Ukuba ukunyamezeleka kakuhle, ichiza kufuneka lilawulwe ubuncinci imizuzu engama-30.
Iidosi ezingaphezulu kwe-3.6 mg / kg akufuneki zenziwe.
Iziphumo ebezingalindelekanga zeKadcyla
Iziphumo ebezingalindelekanga zeKadcyla zezi:
- Ukudinwa;
- Isicaphucaphu nokugabha:
- Ubuhlungu bemisipha;
- Ukunciphisa inani leeplatelet egazini;
- Intloko ebuhlungu;
- Ukwanda kokutshintsha kwesibindi;
- Kuyabanda.
Ukungqinelana kweKadcyla
I-Kadcyla iyaphikiswa ngexesha lokukhulelwa kuba ibangela iingxaki zemfuzo ezinobungozi kwaye ezisongela ubomi.
Amanye amayeza anokusebenzisana neKadcyla njenge
- Imatinib;
- Isoniazid;
- Clarithromycin kunye ne-telithromycin;
- Iziyobisi nokubola;
- Amayeza entliziyo: nicardipine, quinidine;
- Amayeza e-hepatitis C: i-boceprevir, telaprevir;
- Iziyobisi zikaGawulayo;
- Iivithamini kunye neemveliso zendalo.
Ugqirha kufuneka asoloko esaziswa ngamayeza asetyenziswa rhoqo sisigulana okanye awathathayo ngalo mzuzu eqala unyango.