Uvavanyo lweLactate Dehydrogenase (LDH) Isoenzymes

Umxholo

• Yintoni uvavanyo lwe-lactate dehydrogenase (LDH) isoenzymes?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwe-LDH isoenzymes?
• Kwenzeka ntoni ngexesha lovavanyo lwe-LDH isoenzymes?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Izalathiso

Yintoni uvavanyo lwe-lactate dehydrogenase (LDH) isoenzymes?

Olu vavanyo lilinganisa inqanaba le-lactate dehydrogenase (LDH) isoenzymes egazini. I-LDH, ekwabizwa ngokuba yi-lactic acid dehydrogenase, luhlobo lweprotein, eyaziwa njenge-enzyme. I-LDH idlala indima ebalulekileyo ekwenzeni amandla omzimba wakho. Ifunyanwa phantse kuzo zonke izicwili zomzimba.

Kukho iintlobo ezintlanu ze-LDH. Ziyaziwa njengee isoenzymes. Ezi isoenzymes zintlanu zifunyenwe ngokwexabiso elithile kwizicwili emzimbeni wonke.

• I-LDH-1: ifunyenwe entliziyweni nakwiiseli ezibomvu zegazi
• I-LDH-2: ifumaneka kwiiseli ezimhlophe zegazi. Kufunyenwe kwintliziyo kunye neeseli ezibomvu zegazi, kodwa kwixabiso elingaphantsi kwe-LDH-1.
• I-LDH-3: ifunyenwe kwimisipha yemiphunga
• I-LDH-4: ifunyenwe kwiiseli ezimhlophe zegazi, izintso kunye neeseli zepancreas, kunye nee-lymph node
• I-LDH-5: ifumaneka kwisibindi kunye nezihlunu zamathambo

Xa izicwili zonakele okanye zigula, zikhupha i-LDH isoenzymes kwigazi. Uhlobo lwe-LDH isoenzyme ekhutshiweyo ixhomekeke ekubeni zeziphi izicubu ezonakalisiweyo. Olu vavanyo lunokunceda umboneleli wakho ukuba afumane indawo kunye nesizathu somonakalo wethishu yakho.

Amanye amagama: i-LD isoenzyme, i-lactic dehydrogenase isoenzyme

Isetyenziselwa ntoni?

Uvavanyo lwe-LDH isoenzymes lusetyenziselwa ukufumana indawo, uhlobo, kunye nobunzima bomonakalo wethishu. Inokukunceda ukufumanisa iimeko ezahlukeneyo kubandakanya:

• Uhlaselo lwentliziyo lwamva nje
• Ukunqongophala kwegazi
• Isifo sezintso
• Isifo sesibindi, kuquka i-hepatitis kunye ne-cirrhosis
• I-pulmonary embolism, igazi elisongela ubomi kwimiphunga

Kutheni ndifuna uvavanyo lwe-LDH isoenzymes?

Unokulufuna olu vavanyo ukuba umboneleli wakho wokhathalelo lwempilo ukrokrela ukuba unomonakalo wethishu osekwe kwiimpawu zakho kunye / okanye kolunye uvavanyo. Uvavanyo lwe-LDH isoenzymes luhlala lusenziwa njengokulandela kuvavanyo lwe-lactate dehydrogenase (LDH). Uvavanyo lwe-LDH lukwalinganisa amanqanaba e-LDH, kodwa alunikezeli ngolwazi kwindawo okanye kuhlobo lomonakalo wethishu.

Kwenzeka ntoni ngexesha lovavanyo lwe-LDH isoenzymes?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-LDH isoenzymes.

Ngaba bukhona ubungozi kuvavanyo?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Ukuba iziphumo zakho zibonise ukuba amanqanaba enye okanye ngaphezulu ye-LDH isoenzymes ibingaqhelekanga, kusenokwenzeka ukuba uthetha ukuba unesifo esithile okanye umonakalo. Uhlobo lwesifo okanye ukonakala luya kuxhomekeka kwii-isoenzymes ze-LDH ezinamanqanaba angaqhelekanga. Ukuphazamiseka okubangela amanqanaba e-LDH angaqhelekanga kubandakanya:

• Ukunqongophala kwegazi
• Isifo sezintso
• Isifo sesibindi
• Ukulimala kwemisipha
• Ukuhlaselwa yintliziyo
• Ipancreatitis
• I-mononucleosis echaphazelekayo (mono)

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Izalathiso

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6. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2019. Uvavanyo lwegazi lwe-LDH isoenzyme: Amagqabantshintshi [ahlaziywa ngo-2019 ngoJulayi 3; icatshulwe ngo-2019 ngoJulayi 3]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/ldh-isoenzyme-blood-test
7. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2019. Health Encyclopedia: Lactate Dehydrogenase Isoenzymes [icatshulwe ngo-2019 ngoJulayi 3]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=lactate_dehydrogenase_isoenzymes
8. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2019. Health Encyclopedia: Pulmonary Embolism [icatshulwe ngo-2019 ngoJulayi 3]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid=p01308

Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.