Imifanekiso yoTshintsho lwePhysical of MS

Umxholo

• Wenzeka phi umonakalo?
• I-MS igxile kwinkqubo ye-nervous system
• Ukubaluleka kweeseli zemithambo-luvo
• I-MS iqala ngokudumba
• Ukujolisa ekujolise kuko i-myelin
• Iifom ze-Scar tissue kwiindawo ezenzakeleyo
• Ukuvuvukala kunokubulala neeseli glial
• Yintoni eyenzekayo ngokulandelayo?

I-MS iwonakalisa njani umonakalo wayo?

Ukuba wena okanye umntu omthandayo une-multiple sclerosis (MS), sele uyazi malunga neempawu. Zingabandakanya ubuthathaka bemisipha, ingxaki ngokulungelelanisa kunye nokulinganisela, iingxaki zokubona, ukucinga kunye nemiba yokukhumbula, kunye neemvakalelo ezinjenge-numbness, prickling, okanye "izikhonkwane neenaliti."

Into ongayaziyo yindlela esi sifo esizenzekelayo esichaphazela ngayo umzimba. Ngaba iphazamisa njani inkqubo yemiyalezo enceda ingqondo yakho ukuba ilawule izenzo zakho?

Wenzeka phi umonakalo?

Umonakalo wemithambo unokwenzeka naphina kwintambo yomqolo kunye / okanye kwingqondo, yiyo loo nto iimpawu ze-MS zingahluka ukusuka komnye umntu ukuya komnye. Ngokuxhomekeka kwindawo kunye nobunzima bokuhlaselwa kweeseli ezimhlophe, iimpawu zingabandakanya:

• ukulahleka kwemali eseleyo
• ukudumba kwezihlunu
• ubuthathaka
• ukungcangcazela
• iingxaki zamathumbu kunye nesinyi
• iingxaki zamehlo
• ukungeva kakuhle
• iintlungu zobuso
• Imiba yobuchopho njengokulahleka kwememori
• imiba yesondo
• iingxaki ngentetho nokuginya

I-MS igxile kwinkqubo ye-nervous system

I-MS ihlasela izicwili kwingqondo nakumqolo, eyaziwa ngokuba yi inkqubo luvo (CNS). Le nkqubo ibandakanya uthungelwano oluntsonkothileyo lweeseli zemithambo-luvo ezinoxanduva lokuthumela, lokufumana nokutolika ulwazi oluvela kuwo onke amalungu omzimba.

Ngexesha lobomi bemihla ngemihla, intambo yomqolo ithumela ulwazi kwingqondo ngokusebenzisa ezi seli zemithambo-luvo. Ingqondo emva koko iguqulela ulwazi kwaye ilawula indlela osabela ngayo kuyo. Unokucinga ngengqondo njengekhompyuter esembindini kunye nentambo yomqolo njengentambo phakathi kwengqondo kunye nomzimba uphela.

Ukubaluleka kweeseli zemithambo-luvo

Iiseli zemithambo-luvo zihambisa imiyalezo zisuka kwelinye ilungu lomzimba ziye kwelinye ngokusebenzisa umbane kunye nemichiza. Ngamnye unomzimba weseli, i-dendrites, kunye ne-axon. Inkqubo ye- dendrites zizinto ezincinci, ezinjengewebhu eziphuma kumzimba weseli. Basebenza njengee-receptors, befumana imiqondiso evela kwezinye iiseli zemithambo-luvo kwaye bazidlulisele kumzimba weseli.

Inkqubo ye- iazon, ekwabizwa ngokuba yi-fiber fiber, luqikelelo olufana nomsila olusebenza ngokuchaseneyo ne-dendrites: ithumela iimpembelelo zombane kwezinye iiseli zemithambo-luvo.

Izinto ezinamafutha ezaziwa njenge myelin igubungela i-axon yeseli yemithambo-luvo. Esi sigqubuthelo sikhusela kwaye sigubungela i-axon kakhulu njengeqokobhe lerabha ekhusela kwaye igqume intambo yombane.

I-Myelin yenziwe iipilisi (izinto ezinamafutha) kunye neeproteni. Ukongeza ekukhuseleni i-axon, ikwanceda ukuhambisa imithambo-luvo ngokukhawuleza ukusuka kwelinye ilungu lomzimba ukuya kwelinye, okanye kwingqondo. I-MS ihlasela i-myelin, iyaphula kwaye iphazamise iimpawu zemithambo-luvo.

I-MS iqala ngokudumba

Izazinzulu zikholelwa ukuba i-MS iqala ngokudumba. Usulelo olulwa neeseli ezimhlophe zegazi ezibangelwa ngamandla angaziwayo zingena kwi-CNS kwaye zihlasele iiseli zemithambo-luvo.

Oososayensi bacinga ukuba intsholongwane efihlakeleyo, xa ivuliwe, inokubangela ukudumba. Ukubakho kwemfuza okanye ukungasebenzi kakuhle kwamajoni omzimba nako kunokubekek 'ityala. Nokuba yeyiphi na intlantsi, iiseli ezimhlophe zegazi ziyaqhubeka nokuhlasela.

Ukujolisa ekujolise kuko i-myelin

Xa i-spikes yokuvuvukala, i-MS iyasebenza. Ukuhlaselwa kweeseli ezimhlophe zegazi kulimaza i-myelin ekhusela i-nerve fiber (axon). Khawufane ucinge intambo yombane eyonakalisiweyo kunye neengcingo ezibonakalayo, kwaye uya kuba nomfanekiso wendlela imicu yentsimbi ebonakala ngayo ngaphandle kwe-myelin. Le nkqubo ibizwa ngokuba ukutshitshiswa.

Njengokuba intambo yombane eyonakalisiweyo inokuthi ifutshane okanye idale amandla ombane, ifayibha eyonzakeleyo iya kuba nzima ekusebenziseni iimpembelelo zentliziyo. Oku kunokubangela iimpawu ze-MS.

Iifom ze-Scar tissue kwiindawo ezenzakeleyo

Ukuba usikeka engalweni, umzimba wenza ukhwekhwe ngokuhamba kwexesha njengoko usiko lunyanga. Imicu yamathambo nayo yenza izicwili ezibomvu kwiindawo zomonakalo we-myelin. Esi sihlunu siqinile, siqinile, kwaye siyabhloka okanye sithintela ukuhamba kwemiyalezo phakathi kwemithambo-luvo kunye nezihlunu.

Ezi ndawo zomonakalo zibizwa njalo amacwecwe okanye izilonda Kwaye zingumqondiso ophambili wobukho be-MS. Eneneni, igama elithi “multiple sclerosis” lithetha “amanxeba amaninzi.”

Ukuvuvukala kunokubulala neeseli glial

Ngexesha lokudumba, ukuhlasela iiseli ezimhlophe zegazi nako kunokubulala glial iiseli. Iiseli ze-Glial zijikeleze iiseli zemithambo-luvo kwaye zibonelela ngenkxaso kunye nokugquma phakathi kwazo. Zigcina iiseli zemithambo-luvo zisempilweni kwaye zivelisa i-myelin entsha xa yonakele.

Nangona kunjalo, ukuba iiseli ze-glial zibulewe, abanakukwazi ukuqhubeka nokulungiswa. Olunye lophando olutsha lonyango lwe-MS lujolise ekuhambiseni iiseli ezintsha ze-glial kwindawo yomonakalo we-myelin ukunceda ukukhuthaza ukwakhiwa kwakhona.

Yintoni eyenzekayo ngokulandelayo?

Isiqendu se-MS okanye ixesha lomsebenzi wokuvuvukala unokuhlala naphina ukusuka kwiintsuku ezimbalwa ukuya kwiinyanga ezininzi. Kwiindlela zokubuyela umva / zokuxolelwa ze-MS, umntu uhlala enamava "okuxolelwa" kungabikho zimpawu. Ngeli xesha, imithambo-luvo iya kuzama ukuzilungisa kwaye inokwenza iindlela ezintsha zokujikeleza iiseli zemithambo-luvo ezonakeleyo. Ukuxolelwa kunokuhlala kwiinyanga ukuya kwiminyaka.

Nangona kunjalo, iifom zenkqubela phambili ze-MS azibonisi ukuvuvukala okuninzi kwaye akunakubonisa naluphi na uxolelo lweempawu, okanye okona kulungileyo kuya kuba lithafa kuphela emva koko kuqhubeke kudale umonakalo.

Akukho lunyango lwe-MS. Nangona kunjalo, unyango lwangoku lunokusicothisa isifo kwaye luncede ukulawula iimpawu.