Ukuqhubela phambili-ukubuyela kwakhona kwi-Multiple Sclerosis (PRMS)

Umxholo

• Ukuchaza "ukubuyela umva" kwi-PPMS esebenzayo
• Iimpawu ze-PPMS
• Ukuqhubela phambili kwePPMS
• Ukuchonga i-PPMS
• Ukunyanga i-PPMS
• Imbonakalo ye-PPMS

Kukuthini ukubuyela umva kwakhona kwi-multiple sclerosis (PRMS)?

Ngo-2013, iingcali zonyango zachaza kwakhona iintlobo ze-MS. Ngenxa yoko, i-PRMS ayisathathelwa ingqalelo njengolunye lweentlobo ezahlukeneyo ze-MS.

Abantu abanokuthi bafumane ukuxilongwa kwe-PRMS kwixesha elidlulileyo ngoku baqwalaselwa ukuba bane-MS ephambili kunye nesifo esisebenzayo.

Isiseko se-multiple sclerosis (PPMS) saseprayimari siyaziwa ngeempawu eziba mandundu ngokuhamba kwexesha. Esi sifo sinokubonakala ngathi "siyasebenza" okanye "asisebenzi." I-PPMS ithathwa njengesebenzayo ukuba kukho iimpawu ezintsha okanye utshintsho kwi-MRI scan.

Ezona mpawu zixhaphakileyo ze-PPMS zikhokelela kutshintsho lokuhamba, kwaye zinokubandakanya:

• utshintsho kwi-gait
• iingalo nemilenze elukhuni
• imilenze enzima
• ukungakwazi ukuhamba imigama emide

Ukuqhubela phambili ukuphinda ubuye kwakhona i-sclerosis (PRMS) kubhekisa kwi-PPMS nesifo esisebenzayo. Ipesenteji encinci yabantu abane-multiple sclerosis (MS) banolu hlobo oluqhubekayo lokubuyela kwesi sifo.

Ukuchaza "ukubuyela umva" kwi-PPMS esebenzayo

Ekuqaleni kwe-MS, abanye abantu bahamba ngokuhla kweempawu. Ngamanye amaxesha ababonisi nayiphi na imiqondiso ye-MS kangangeentsuku okanye iiveki ngexesha.

Nangona kunjalo, ngexesha lokulala, iimpawu zinokubonakala ngaphandle kwesixwayiso. Oku kunokubizwa ngokuba kukuphinda ubuye kwi-MS, ukunyusa amandla, okanye ukuhlaselwa. Ukuphinda ubuye luphawu olutsha, ukuphindaphinda kweempawu ezindala ezazingcono ngaphambili, okanye ukonakala kwempawu endala ehlala ngaphezulu kweeyure ezingama-24.

Ukubuyela kwakhona kwi-PPMS esebenzayo kwahlukile ekubuyeleni kwakhona ekubuyiseleni kwakhona ekuphindaphindeni kwesclerosis (RRMS).

Abantu abanePPMS banamava okuhamba kancinci kweempawu. Iimpawu zingangcono kancinci kodwa zingaze ziphele ngokupheleleyo. Ngenxa yokuba iimpawu zokubuyela umva azizange ziye kwi-PPMS, umntu one-PPMS uhlala eneempawu ze-MS ngaphezulu kunomntu oneRRMS.

Nje ukuba i-PPMS esebenzayo ikhule, ukubuyela umva kunokwenzeka ngokuzenzekelayo, ngaphandle kwonyango.

Iimpawu ze-PPMS

Iimpawu zokuhamba ziphakathi kweyona miqondiso iqhelekileyo ye-PPMS, kodwa ubungqongqo kunye neentlobo zeempawu zinokwahluka ukusuka komnye umntu ukuya komnye. Eminye imiqondiso eqhelekileyo ye-PPMS esebenzayo inokubandakanya:

• ukudumba kwezihlunu
• izihlunu ezibuthathaka
• kunciphise umsebenzi wesinyi, okanye ukungakwazi ukuzibamba
• isiyezi
• iintlungu ezingapheliyo
• utshintsho lombono

Njengoko isifo siqhubeka, i-PPMS inokubangela iimpawu eziqhelekileyo ezifana ne:

• utshintsho kwintetho
• ukungcangcazela
• ukungeva kakuhle

Ukuqhubela phambili kwePPMS

Ngaphandle kokubuyela umva, i-PPMS esebenzayo ikwaphawulwa ngokuqhubekeka okungaguqukiyo kokuncipha komsebenzi we-neurological.

Oogqirha abanako ukuqikelela inqanaba ngqo lenkqubela phambili ye-PPMS. Kwiimeko ezininzi, ukuqhubela phambili yinkqubo ecothayo kodwa ethe chu ehamba iminyaka eliqela. Ezona meko ze-PPMS zibi ziphawulwa kukuqhubela phambili ngokukhawuleza.

Ukuchonga i-PPMS

I-PPMS inokuba nzima ukuyichonga ekuqaleni. Oku ngokuyinxenye kuba ukubuyela kwakhona kwi-PPMS akubonakali njengoko kunjalo kwezinye iindlela ezingekho qatha ze-MS.

Abanye abantu bayakudlula ukubuyela umva njengesiphumo sokuba neentsuku ezimbi kunokuba bacinge ukuba ziimpawu zesifo esonyukayo. I-PPMS ifunyaniswa ngoncedo lwe:

• Uvavanyo lweelebhu, njengokuvavanywa kwegazi kunye nokugqobhoza i-lumbar
• Ukuskena iMRI
• iimviwo ze-neurological
• Imbali yonyango lomntu echaza utshintsho olwenzekayo

Ukunyanga i-PPMS

Unyango lwakho luya kugxila ekuncedeni ukulawula ukubuyela umva. Olona nyango luvunyiweyo lwe-FDA lwe-PPMS yi-ocrelizumab (Ocrevus).

Amayeza yinto enye yonyango lwe-MS. Ugqirha wakho unokucebisa notshintsho kwindlela yokuphila ukunceda ukunciphisa iimpawu zakho kunye nokuphucula umgangatho wobomi. Umsebenzi oqhelekileyo womzimba kunye nesondlo kunokuncedisa unyango lwe-MS.

Imbonakalo ye-PPMS

Okwangoku alukho unyango lwe-MS.

Njengezinye iintlobo zesifo, unyango lunokunceda ukunciphisa inkqubela phambili ye-PPMS. Unyango lunokunciphisa iimpawu.

Ungenelelo kwangoko kwezonyango lunokunceda ukuthintela isifo ekuchaphazelekeni kakhulu kwinqanaba lakho lobomi. Nangona kunjalo, kubalulekile ukufumana uxilongo olufanelekileyo kugqirha wakho ukuze uqiniseke ukuba ufumana ukhathalelo olwaneleyo.

Abaphandi bayaqhubeka nokufunda i-MS ukuze baqonde imeko yesi sifo kwaye bajonge nonyango.

Izifundo zeklinikhi ze-PPMS zixhaphake kakhulu kunezinye iintlobo zesifo kuba akukho lula ukusibona. Inkqubo yokugaya iimvavanyo zeklinikhi inokuba nzima ngenxa yokunqaba kolu hlobo lwe-MS.

Uninzi lwezilingo zamayeza okufunda e-PPMS ukulawula iimpawu. Ukuba unomdla wokuthatha inxaxheba kuvavanyo lweklinikhi, xoxa ngeenkcukacha kunye nogqirha wakho.