Isifo seSerotonin

Umxholo

• Zithini iimpawu zeserotonin syndrome?
• Zithini izizathu zeserotonin syndrome?
• Ukudakumba
• Amayeza e-migraine (icandelo le-triptan)
• Iziyobisi ezingekho mthethweni
• Izongezo zemifuno
• Ingqele kunye nokukhohlela amayeza
• Ichongwa njani i-serotonin syndrome?
• Luthini unyango lwe-serotonin syndrome?
• Zeziphi iingxaki ezinxulunyaniswa neserotonin syndrome?
• Ithini imbono yexesha elide?
• Ndingayithintela njani i-serotonin syndrome?

Yintoni i-serotonin syndrome?

Iserotonin syndrome sisenzo esibi sokusabela gwenxa kweziyobisi. Kukholelwa ukuba kwenzeka xa i-serotonin eninzi iyakha emzimbeni wakho. Iiseli zamathambo zihlala zivelisa i-serotonin. I-Serotonin yi-neurotransmitter, eyikhemikhali. Inceda ukumisela:

• ukwetyisa
• ukuhamba kwegazi
• ubushushu bomzimba
• ukuphefumla

Ikwadlala indima ebalulekileyo ekusebenzeni kakuhle kweeseli kunye neeseli zengqondo kwaye kukholelwa ukuba inefuthe kwiimvakalelo.

Ukuba uthatha amayeza ahlukeneyo kunye, unokuphela une-serotonin eninzi emzimbeni wakho. Iindidi zonyango ezinokukhokelela kwisifo se-serotonin zibandakanya ezo zisetyenziselwa ukunyanga uxinzelelo kunye neentloko zentloko, kunye nokulawula iintlungu. I-serotonin eninzi inokubangela iintlobo ezahlukeneyo zobumnene ukuya kwiimpawu ezinzima. Ezi mpawu zinokuchaphazela ingqondo, izihlunu, kunye namanye amalungu omzimba.

Iserotonin syndrome inokwenzeka xa uqala iyeza elitsha eliphazamisa i-serotonin. Inokwenzeka kwakhona ukuba uyonyusa idosi yonyango osele uyithatha. Imeko inokwenzeka ukuba yenzeke xa kuthathwa amachiza amabini okanye nangaphezulu. I-Serotonin syndrome inokubulala xa ungafumani unyango ngokukhawuleza.

Zithini iimpawu zeserotonin syndrome?

Unokuba neempawu ngaphakathi kwemizuzu okanye iiyure zokuthatha amayeza amatsha okanye ukonyusa umthamo wamayeza akhoyo. Iimpawu zingabandakanya:

• ukudideka
• ukudideka
• ukucaphuka
• ixhala
• ukudumba kwezihlunu
• ukuqina kwemisipha
• ukungcangcazela
• ndingcangcazela
• urhudo
• ukubetha kwentliziyo okukhawulezayo, okanye i-tachycardia
• igazi elonyukayo
• isicaphucaphu
• nemibono
• Ukucamngca okungaphaya, okanye ihyprereflexia
• abafundi abaxubileyo

Kwiimeko ezinzima kakhulu, iimpawu zingabandakanya:

• ukungaphenduli
• ikhoma
• ukuxhuzula
• ukubetha kwentliziyo ngokungaqhelekanga

Zithini izizathu zeserotonin syndrome?

Ngokwesiqhelo, imeko yenzeka xa udibanisa amayeza amabini okanye nangaphezulu, iziyobisi ezingekho mthethweni, okanye izongezo zesondlo ezonyusa amanqanaba e-serotonin. Umzekelo, ungathatha iyeza ukunceda nge-migraine emva kokuba sele uthathe i-anti-depressant. Iindidi ezithile zamayeza amiselweyo, anje ngee-antibiotics, ii-antivirals ezisetyenziselwa ukunyanga i-HIV kunye ne-AIDS, kunye namanye amayeza kagqirha wesicaphucaphu kunye nentlungu inokunyusa amanqanaba e-serotonin.

Imizekelo yeziyobisi kunye nezongezo ezinxulumene nesifo se-serotonin zibandakanya:

Ukudakumba

Ukudakumba okuhambelana neserotonin syndrome kubandakanya:

• i-serotonin reuptake inhibitors ekhethiweyo (i-SSRIs), enje ngeCelexa kunye neZoloft
• i-serotonin kunye ne-norepinephrine reuptake inhibitors (i-SNRIs), efana ne-Effexor
• i-tricyclic antidepressants, enje nge-nortriptyline kunye ne-amitriptyline
• i-monoamine oxidase inhibitors (i-MAOIs), efana neNardil neMarplan
• ezinye izidambisi zengqondo

Amayeza e-migraine (icandelo le-triptan)

Amayeza e-Migraine kwicandelo leziyobisi elibizwa ngokuba yi "triptans" adityaniswa ne-serotonin syndrome. Oku kubandakanya:

• almotriptan (igwebu)
• naratriptan (Amerge)
• is sumatriptan (Imitrex)

Iziyobisi ezingekho mthethweni

Ezinye iziyobisi ezingekho mthethweni zinxulunyaniswa neserotonin syndrome. Oku kubandakanya:

• I-LSD
• ukonwaba (MDMA)
• icocaine
• amphetamines

Izongezo zemifuno

Ezinye izongezo zemifuno zinxulunyaniswa neserotonin syndrome. Oku kubandakanya:

• Wort yaseSt
• ginseng

Ingqele kunye nokukhohlela amayeza

Amanye amayeza okubanda kunye nokukhohlela aqukethe i-dextromethorphan inxulunyaniswa neserotonin syndrome. Oku kubandakanya:

• Indawo yeRobitussin
• UDelsym

Ichongwa njani i-serotonin syndrome?

Akukho vavanyo lwelabhoratri oluthile lwe-serotonin syndrome. Ugqirha wakho unokuqala ngokujonga kwakhona imbali yakho kunye neempawu zonyango. Qiniseka ukuba uxelela ugqirha wakho ukuba uthatha nawaphi na amayeza okanye usebenzise iziyobisi ezingekho mthethweni kwezi veki zidlulileyo. Olu lwazi lunokunceda ugqirha wakho enze uxilongo oluchanekileyo ngakumbi.

Ugqirha wakho uhlala esenza ezinye iimvavanyo. Oku kuya kunceda ugqirha wakho afumanise ukuba amalungu athile okanye imisebenzi yomzimba ichaphazele. Banokukunceda ugqirha wakho akhuphe ezinye iimeko.

Ezinye iimeko zineempawu ezifanayo kwi-serotonin syndrome. Oku kubandakanya usulelo, ukugqithisa kweziyobisi, kunye neengxaki zehomoni. Imeko eyaziwa ngokuba yi-neuroleptic malignant syndrome nayo ineempawu ezifanayo. Kukusabela okungalunganga kumayeza asetyenziselwa ukunyanga izifo zengqondo.

Uvavanyo ugqirha wakho unokuyalela kubandakanya:

• ubalo olupheleleyo lwegazi (CBC)
• inkcubeko yegazi
• Uvavanyo lwe-thyroid
• izikrini zeziyobisi
• Uvavanyo lwezintso
• Uvavanyo lomsebenzi wesibindi

Luthini unyango lwe-serotonin syndrome?

Ukuba unetyala elincinci le-serotonin, ugqirha unokukucebisa ukuba uyeke ngokukhawuleza ukuthatha amayeza abangela ingxaki.

Ukuba unempawu ezinzima, kuya kufuneka uye esibhedlele. Esibhedlele, ugqirha wakho uya kujonga imeko yakho. Unokufumana olu nyango lulandelayo:

• Ukurhoxiswa kwalo naliphi na iyeza elibangele imeko
• ulwelo olufakwa emithanjeni lokuphelelwa ngamanzi emzimbeni kunye nomkhuhlane
• amayeza anceda ukunciphisa ukuqina kwemisipha okanye ukuphazamiseka
• amayeza athintela i-serotonin

Zeziphi iingxaki ezinxulunyaniswa neserotonin syndrome?

Ukuqaqamba kwemisipha kungakhokelela ekonakaleni kwezihlunu zemisipha. Ukonakala kwesi sihlunu kungakhokelela ekonakaleni kwezintso. Isibhedlele sinokufuna ukusebenzisa amayeza okhubaza okwethutyana izihlunu zakho ukuthintela umonakalo ongaphezulu. Umbhobho wokuphefumla kunye nokuphefumla kuya kukunceda uphefumle.

Ithini imbono yexesha elide?

Imbonakalo yeserotonin syndrome ilungile kakhulu kunyango. Kukho iingxaki ezingaphaya xa amanqanaba e-serotonin ebuyela esiqhelweni. Nangona kunjalo, i-serotonin syndrome inokubulala xa inganyangwa.

Ndingayithintela njani i-serotonin syndrome?

Awunakuhlala uthintela i-serotonin syndrome. Qiniseka ukuba ugqirha wakho uyazi ukuba ngawaphi amayeza owathathayo. Ugqirha wakho kufuneka akubeke esweni ngokusondeleyo ukuba uthatha indibaniselwano yamayeza awaziwayo ukwandisa amanqanaba e-serotonin. Oku kubaluleke ngakumbi kanye emva kokuba uqale iyeza elitsha okanye kanye emva kokonyusa idosi yakho.

I-FDA ifuna iilebhile ezilumkisayo kwiimveliso ukulumkisa abaguli ngomngcipheko wesifo se-serotonin.