Ziziphi iziphumo ezibi kunyango lweHepatitis C?

Umxholo

• Izinketho zonyango
• IiDAA
• Ribavirin
• Ii-interferon
• Iziphumo zonyango
• IiDAA
• Ribavirin
• Ii-interferon
• Ukuthatha

Ushwankathelo

I-Hepatitis C virus (HCV) yintsholongwane enenkani kodwa eqhelekileyo ehlasela isibindi. Malunga nezigidi ezi-3.5 zabantu e-United States bane-hepatitis C. engapheliyo, okanye yexesha elide.

Kunganzima ukuba amajoni omzimba omntu alwe ne-HCV. Ngethamsanqa, zininzi iziyobisi ezikhoyo zokunyanga i-hepatitis C. Funda ukuze ufunde ngakumbi malunga nonyango lwe-hepatitis C kunye neziphumo ebezingalindelekanga.

Izinketho zonyango

Ezona ntlobo ziphambili zamayeza e-HCV amiselweyo namhlanje zii-antivirals (DAAs) kunye ne-ribavirin. Kwiimeko ezinqabileyo apho ii-DAA zingafikeleleki, ii-interferon zinokumiselwa.

IiDAA

Namhlanje, iiDAA zikumgangatho wokhathalelo kwabo bane hepatitis enganyangekiyo C.

La machiza anokufumaneka njengamachiza athile okanye njengenxalenye yonyango oludibeneyo. Onke la mayeza athathwa ngomlomo.

Umntu ngamnye weDAA

• dasabuvir
• idaclatasvir (iDaklinza)
• simeprevir (Olysio)
• isofosbuvir (Sovaldi)

Umdibaniso weDAAs

• I-Epclusa (sofosbuvir / velpatasvir)
• IHarvoni (ledipasvir / sofosbuvir)
• Imavyret (glecaprevir / pibrentasvir)
• Itekhnoloji (ombitasvir / paritaprevir / ritonavir)
• IViekira Pak (dasabuvir + ombitasvir / paritaprevir / ritonavir)
• I-Vosevi (sofosbuvir / velpatasvir / voxilaprevir)
• I-Zepatier (elbasvir / grazoprevir)

Ribavirin

I-Ribavirin liyeza elisetyenziswa ngokudibanisa namanye amayeza ukunyanga i-HCV. Isetyenziselwa ukumiselwa ikakhulu ngee-interferon. Namhlanje isetyenziselwa ii-DAA ezithile ngokuchasene nosulelo lwe-HCV olunganyangekiyo. I-Ribavirin ihlala isetyenziswa neZepatier, Viekira Pak, Harvoni, kunye neTechnivie.

Ii-interferon

Ii-interferon ngamayeza awayefudula elunyango lwe-HCV. Kwiminyaka yakutshanje, iiDAA zithathe loo ndima. Oku ikakhulu kungenxa yokuba ii-DAAs zibangela iziphumo ebezingalindelekanga ezimbalwa kakhulu kunokuba kunjalo ii-interferon. Ii-DAA ziyakwazi ukunyanga i-HCV rhoqo.

Ngelixa iziphumo ebezingalindelekanga zixhalabisayo ngexesha lonyango lwe-hepatitis C, kuya kufuneka ujonge ekubeni sempilweni. Kuya kufuneka utye ukutya okunesondlo, okunesondlo kwaye uqiniseke ukuba usele amanzi amaninzi ukunqanda ukomisa. Kukwabalulekile ukunqanda ukutshaya notywala kuba le mikhwa inokuba nefuthe elibi kakhulu kwimpilo yabantu abane-hepatitis C.

Iziphumo zonyango

Iziphumo ebezingalindelekanga ziyahluka ngohlobo lweziyobisi ezisetyenziselwa ukunyanga i-HCV.

IiDAA

IiDAA azibangeli inani leziphumo ebezingalindelekanga ezenziwa zii-interferon. Zijolise ngakumbi kwaye azichaphazeli iinkqubo ezininzi emzimbeni wakho. Iziphumo ebezingalindelekanga zeDAA zinokubandakanya:

• ianemia
• urhudo
• ukudinwa
• intloko ebuhlungu
• isicaphucaphu
• ukugabha
• ukubetha kwentliziyo kancinci
• Iimpawu eziphakanyisiweyo zesibindi, ezinokubonisa iingxaki zesibindi

Ribavirin

Iziphumo eziqhelekileyo eziqhelekileyo ze-ribavirin zingabandakanya:

• isicaphucaphu nokugabha
• irhashalala
• utshintsho kubuchule bakho bokungcamla
• ukulahleka kwememori
• ingxaki yokujonga
• ubunzima bokulala
• iintlungu zemisipha
• i-hemolytic anemia

Iziphumo ebezingalindelekanga ezibi kakhulu ze-ribavirin zinxulumene nokukhulelwa. I-Ribavirin inokubangela iziphene zokuzalwa ukuba zithathiwe xa ukhulelwe. Isenokubangela iziphene zokuzalwa ukuba indoda iyazala umntwana ngexesha lonyango lwe-ribavirin.

Ii-interferon

Iziphumo eziqhelekileyo ezichaphazelekayo ze-interferon zingabandakanya:

• umlomo owomileyo
• ukudinwa kakhulu
• intloko ebuhlungu
• ukutshintsha kwemood, ezinje ngexhala okanye uxinzelelo
• ingxaki yokulala
• ukuhla ukusinda
• ukulahleka kweenwele
• ukwanda kweempawu zesibindi

Ezinye iziphumo ebezingalindelekanga ezimandundu zinokwenzeka ekuhambeni kwexesha. Ezi ziphumo zingabandakanya:

• Ukuphazamiseka komzimba
• kunciphise amanqanaba egazi abomvu namhlophe anokukhokelela kwi-anemia kunye nosulelo
• igazi elonyukayo
• ukunciphisa umsebenzi we-thyroid
• utshintsho kumbono
• isifo sesibindi
• isifo semiphunga
• ukudumba kwamathumbu akho okanye ipancreas
• negazi lakho
• ukukhula okucothayo ebantwaneni

Ukuthatha

Kwixesha elidlulileyo, iziphumo ebezingalindelekanga ezimandundu ezivela kwii-interferon zabangela ukuba abantu abaninzi bayeke unyango lwe-HCV. Ngethamsanqa, oku akusekho njalo, njengoko iiDAAs ngoku zikumgangatho wokhathalelo. La machiza abangela iziphumo ebezingalindelekanga ezimbalwa kakhulu kunezo zenziwa zii-interferon, kwaye uninzi lwazo zibangelwe kukuhamba kwexesha.

Ukuba uphathwa nge-HCV kwaye uneziphumo ebezingalunganga ezikukhathazayo okanye ezikuxhalabisayo, qiniseka ukuba uthethe nogqirha wakho. Banokunceda ekunciphiseni ezi ziphumo bezingalindelekanga ngokunciphisa idosi okanye ukukutshintshela kwelinye iyeza.