I-hepatorenal syndrome: yintoni, izizathu kunye nonyango

Umxholo

• Iindidi zeHepatorrenal Syndrome
• Izizathu ezinokubangela
• Ziintoni iimpawu
• Unyango lwenziwa njani

I-Hepatorenal syndrome yinkxalabo enzulu edla ngokuzibonakalisa kubantu abanezifo eziphambili zesibindi, ezifana ne-cirrhosis okanye ukungaphumeleli kwesibindi, esabonakaliswa ngokuthotywa komsebenzi wezintso, apho i-vasoconstriction eqinile yenzeka khona, ekhokelela ekunciphiseni okuphawulekayo kwinqanaba le-glomerular ukuhluza kwaye ngenxa yokusilela kwezintso. Kwelinye icala, i-vasodilation eyongezelelweyo ye-renal iyenzeka, ekhokelela kwinkqubo ye-hypotension.

I-Hepatorenal syndrome yimeko ebulalayo ngokubanzi, ngaphandle kokuba kwenziwa ukufakelwa isibindi, lolunyango olukhethwayo kwesi sifo.

Iindidi zeHepatorrenal Syndrome

Iindidi ezimbini ze-hepatorrenal syndrome zinokwenzeka. Uhlobo lwe-1, olunxulunyaniswa nokusilela okukhawulezileyo kwezintso kunye nokuveliswa kakhulu kwe-creatinine, kunye nohlobo lwe-2, olunxulunyaniswa nokusilela kwezintso kancinci, okuhamba neempawu ezifihlakeleyo ngakumbi.

Izizathu ezinokubangela

Ngokubanzi, i-hepatorrenal syndrome ibangelwa yi-cirrhosis yesibindi, umngcipheko onokuthi unyuke xa kuselwa iziselo ezinxilisayo, usulelo lwezintso lwenzeka, ukuba umntu unoxinzelelo lwegazi olungazinzanga, okanye ukuba usebenzisa i-diuretics.

Ukongeza kwi-cirrhosis, ezinye izifo ezinxulunyaniswa nokusilela kwesibindi okungapheliyo kunye noxinzelelo lwe-portal, ezinje nge-hepatitis enotywala kunye nokusilela kwesibindi okunamandla nako kunokubangela isifo se-hepatorrenal syndrome. Funda indlela yokuchonga i-cirrhosis yesibindi kunye nokuba isifo sifunyanwa njani.

Ezi ngxaki zesibindi zikhokelela kwi-vasoconstriction eyomeleleyo kwizintso, ekhokelela ekunciphiseni okuphawulekayo kwinqanaba lokuhluza i-glomerular kunye nesiphumo sokungaphumeleli kwe-renal.

Ziintoni iimpawu

Ezona mpawu zixhaphakileyo ezinokubangelwa yi-hepatorrenal syndrome yi-jaundice, ukunciphisa ukuphuma komchamo, umchamo omnyama, ukudumba kwesisu, ukudideka, i-delirium, isicaphucaphu kunye nokugabha, isifo sengqondo esixhalabisayo kunye nokuzuza ubunzima.

Unyango lwenziwa njani

Ukufakelwa kwesibindi lunyango lokhetho kwi-hepatorrenal syndrome, evumela ukuba izintso ziphinde zibuye. Nangona kunjalo, i-dialysis ingafuneka ukuzinzisa isigulana. Fumanisa ukuba yenziwa njani i-hemodialysis kwaye ingaba yintoni le ngozi yonyango.

Ugqirha unokumisela i-vasoconstrictors, enegalelo ekunciphiseni umsebenzi we-vasoconstrictors, ukwandisa ukwanda kwegazi kwezintso. Ukongeza, zikwasetyenziselwa ukulungisa uxinzelelo lwegazi, oluhlala lusezantsi emva koxilongo. Ezona zisetyenziswa kakhulu zii-analogue ze-vasopressin, ezinje nge-terlipressin, umzekelo, kunye ne-alpha-adrenergics, efana ne-adrenaline kunye ne-midodrine.