Uvavanyo lweprogestogen: yintoni, xa iboniswa kwaye yenziwa njani

Umxholo

• Xa kubonisiwe
• Kwenziwa njani
• Oko kuthethwa sisiphumo
• 1. Iziphumo ezilungileyo
• 2. Iziphumo ezingalunganga
• Uthini umahluko kuvavanyo lweprogesterone?

Uvavanyo lweprogestogen lwenziwa ukujonga amanqanaba ehomoni aveliswa ngabafazi xa bengenaxesha liqhelekileyo lokuya exesheni kunye nokuvavanya ukuthembeka kwesibeleko, njengoko iprogestogen iyihomoni ekhuthaza utshintsho kwi-endometrium kwaye igcina ukukhulelwa.

Uvavanyo lweprogestogen lwenziwa ngokulawula iiprogestogen, eziyincindi yamadlala ethintela ukuveliswa kwehomoni zesini i-estrogen kunye neprogesterone, kangangeentsuku ezisixhenxe. Emva kwexesha lolawulo, kuyajongwa ukuba kuye kwaphuma igazi okanye akunjalo, yiyo loo nto ugqirha wamanina ekwazi ukuvavanya impilo yowasetyhini.

Olu vavanyo lusetyenziswa ngokubanzi kuphando lwe-amenorrhea yesibini, eyimeko apho abantu basetyhini bayayeka ukuya exesheni kangangemijikelezo emithathu okanye kwiinyanga ezintandathu, ezinokubangelwa kukukhulelwa, ukuya exesheni, ukusetyenziswa kwezicwangcisi, uxinzelelo lomzimba okanye lweemvakalelo kunye nokuzilolonga rhoqo. . Funda ngakumbi malunga ne-amenorrhea yesibini kunye nezizathu zayo eziphambili.

Xa kubonisiwe

Uvavanyo lweprogestogen luboniswa ngugqirha wezifo zabasetyhini ukuvavanya ukuveliswa kwehomoni ngabafazi, becelwa ikakhulu kuphando lwe-amenorrhea yesibini, imeko apho umfazi eyeka ukuya exesheni kangangemijikelezo emithathu okanye kwiinyanga ezintandathu, enokubangelwa kukukhulelwa, ukuya exesheni, ukusebenzisa izinto zokuthintela ukukhulelwa, uxinzelelo lweemvakalelo okanye umzimba kunye nokuzilolonga rhoqo.

Ke, olu vavanyo luboniswa xa umfazi enezinye zezi zinto zilandelayo:

• Ukungabikho exesheni;
• Imbali yokuqhomfa okuzenzekelayo;
• Iimpawu zokukhulelwa;
• Ukukhawuleza ukunciphisa umzimba;
• Ukusetyenziswa kokuthintela ukukhulelwa;
• Ukuyeka ukuya exesheni.

Uvavanyo lukwaboniswa kwabasetyhini abane-polycystic ovary syndrome, apho ama-cysts amaninzi avela ngaphakathi kwi-ovary enokuphazamisa inkqubo ye-ovulation, eyenza ukukhulelwa kube nzima ngakumbi. Funda ngakumbi malunga ne-polycystic ovary syndrome.

Kwenziwa njani

Uvavanyo lwenziwa ngokulawulwa kwe-10 mg ye-medroxyprogesterone acetate kangangeentsuku ezisixhenxe. Eli yeza lisebenza njengokuthintela ukukhulelwa, oko kukuthi, kuthintela ukufihlwa kwamahomoni anoxanduva lwe-ovulation kunye nokunciphisa ubukhulu be-endometrium, ngaphandle kokuya exesheni. Ke, ekupheleni kokusetyenziswa kweyeza, iqanda linokuya esibelekweni ukuze lichumise. Ukuba akukho kuchumisa, ukopha kuyakwenzeka, kubonisa ukuba sexesheni kwaye kuvavanyo kuthiwa kulungile.

Ukuba iziphumo zolu vavanyo azichazi, oko kukuthi, ukuba akukho ukuphuma kwegazi, kufuneka kwenziwe olunye uvavanyo ukuze kuqinisekiswe ezinye izizathu ezinokubangela i-amenorrhea yesibini. Olu vavanyo lubizwa ngokuba luvavanyo lwe-estrogen kunye neprogestogen kwaye lwenziwa ngokulawulwa kwe-1.25 mg ye-estrogen kangangeentsuku ezingama-21 ngokudibanisa kwe-10 mg ye-medroxyprogesterone acetate kwiintsuku ezili-10 ezidlulileyo. Emva kweli xesha, kuyajongwa ukuba kuye kwaphuma igazi na okanye hayi.

Oko kuthethwa sisiphumo

Uvavanyo lweprogestogen lwenziwa phantsi kokhokelo lonyango kwaye lunokuba neziphumo ezibini ngokweempawu anokuba nazo lowo mfazi emva kokusebenzisa i-medroxyprogesterone acetate.

1. Iziphumo ezilungileyo

Uvavanyo oluqinisekileyo lolunye apho, emva kweentsuku ezintlanu ukuya kwezisixhenxe zokusebenzisa i-medroxyprogesterone acetate, ukopha kwenzeka. Ukopha oku kubonisa ukuba umfazi unesibeleko esiqhelekileyo kwaye amanqanaba e-estrogen nawo aqhelekile. Oku kunokuthetha ukuba umfazi uhamba ixesha elide ngaphandle kwe-ovulation ngenxa yemeko ethile, enjenge-polycystic ovary syndrome okanye utshintsho lwehomoni olubandakanya i-thyroid, i-adrenal gland okanye i-hormone prolactin, kwaye ugqirha kufuneka enze uphando.

2. Iziphumo ezingalunganga

Olu vavanyo luthathwa ngokuba alunayo xa kungekho ukopha emva kweentsuku ezintlanu ukuya kwezisixhenxe. Ukungabikho kokopha kunokubonisa ukuba lo mfazi une-Asherman's syndrome, apho kukho amanxeba amaninzi esibelekweni, abangela ukuba izicwili ze-endometrium zigqithise. Oku kugqithisa kuvumela ukubambelela ukuba kwenziwe ngaphakathi kwesibeleko, okuthintela ukuphuma exesheni kwegazi, elinokuba buhlungu emfazini.

Emva kwesiphumo esibi, ugqirha unokubonisa ukusetyenziswa kwe-1.25 mg ye-estrogen kangangeentsuku ezingama-21 kunye nokongezwa kwe-10 mg ye-medroxyprogesterone acetate kwiintsuku ezili-10 ezidlulileyo. Ukuba emva kokusebenzisa iyeza kukho ukopha (uvavanyo olululo), oko kuthetha ukuba umfazi unendawo yesiqhelo ye-endometrium kwaye amanqanaba e-estrogen asezantsi. Ke kuyacetyiswa ukulinganisa iihormone ezikhuthaza ukuveliswa kwe-estrogen kunye neprogesterone, ezizezona zihomoni ze-luteinizing, i-LH, kunye ne-follicle evuselelayo, i-FSH, ukufumana oyena nobangela wokungabikho exesheni kunye nokuqala unyango olufanelekileyo.

Uthini umahluko kuvavanyo lweprogesterone?

Ngokungafaniyo novavanyo lweprogestogen, uvavanyo lweprogesterone lwenziwa ukujonga ukujikeleza kwamanqanaba eprogesterone egazini. Uvavanyo lweprogesterone luhlala lucelwa kwiimeko zokukhulelwa okusemngciphekweni omkhulu, ubunzima bokukhulelwa kunye nokuya esikhathini ngokungaqhelekanga. Qonda ngakumbi malunga novavanyo lweprogesterone.