Thrombophilia: yintoni, iimpawu, oonobangela kunye nonyango

Umxholo

• Iimpawu eziphambili
• Yintoni enokubangela i-thrombophilia
• 1. Oonobangela abafunyenweyo
• 2. Izizathu zofuzo
• Zithini iimviwo ekufuneka zenziwe
• Unyango lwenziwa njani

I-Thrombophilia yimeko apho abantu bakufumanisa kulula ukwenza amahlwili egazi, ukwandisa umngcipheko weengxaki ezinje nge-venous thrombosis, stroke okanye i-pulmonary embolism, umzekelo. Ke, abantu abanale meko bahlala befumana ukudumba emzimbeni, ukudumba kwemilenze okanye ukuphefumla kancinci.

Amahlwili akhiwa yi-thrombophilia avela ngenxa yokuba ii-enzyme zegazi, ezenza ukujiya, ziyeke ukusebenza kakuhle. Oku kunokwenzeka ngenxa yezizathu zofuzo, ngenxa yemfuza, okanye kunokwenzeka ngenxa yoonobangela abafunyenwe kubomi bonke, njengokukhulelwa, ukutyeba kakhulu okanye umhlaza, kwaye amathuba anokunyuka ngenxa yokusetyenziswa kwamayeza, njengokucwangcisa ngomlomo.

Iimpawu eziphambili

I-thrombophilia yonyusa amathuba e-thrombosis enza egazini kwaye, ke, iimpawu zinokuvela kwimeko yeengxaki kwindawo ethile yomzimba, enje:

• I-vein thrombosis enzulu: ukudumba kwenxalenye yeglasi, ngakumbi imilenze, edumbileyo, ebomvu kwaye ishushu. Qonda ukuba yintoni i-thrombosis kwaye uyichonga njani;
• Ukudibanisa iipulmonary: ukuphefumla kakhulu kunye nokuphefumla nzima;
• Ukubethaukulahleka kwentshukumo ngesiquphe, intetho okanye umbono, umzekelo;
• I-thrombosis kwi-placenta okanye i-umbilical cord: Ukuphuma kwesisu rhoqo, ukuzalwa ngaphambi kwexesha kunye neengxaki zokukhulelwa, njenge-eclampsia.

Kwiimeko ezininzi, umntu usenokungazi ukuba une-thrombophilia de kuvele ukudumba ngesiquphe, ukhupha izisu rhoqo okanye iingxaki ngexesha lokukhulelwa. Kuqhelekile ukubonakala kubantu abadala, kuba ubuthathaka obubangelwa bubudala bunokuqhubela phambili ukuqala kweempawu.

Yintoni enokubangela i-thrombophilia

Ukuphazamiseka kwegazi ekunqandeni igazi okwenzeka kwi-thrombophilia kunokufunyanwa kubomi bonke, okanye kwilifa, kudluliswe kubazali kuye ebantwaneni, ngemfuza. Ke, oyena nobangela uphambili kubandakanya:

1. Oonobangela abafunyenweyo

Oonobangela abaphambili be-thrombophilia efunyenweyo zezi:

• Ukutyeba kakhulu;
• Iimvumba ze-Varicose;
• Ukuqhekeka kwamathambo;
• Ukukhulelwa okanye i-puerperium;
• Isifo sentliziyo, infarction okanye ukusilela kwentliziyo;
• Iswekile, uxinzelelo lwegazi okanye icholesterol ephezulu;
• Ukusetyenziswa kwamayeza, njengokucwangcisa ngomlomo okanye ukutshintshwa kwehomoni. Qonda indlela izinto zokucwangcisa ezinokuwonyusa ngayo umngcipheko we-thrombosis;
• Hlala ebhedini iintsuku ezininzi, ngenxa yotyando, okanye ukulaliswa esibhedlele;
• Ukuhlala ixesha elide kwinqwelo-moya okanye kuhambo lwebhasi;
• Izifo ezisebenza ngokuzenzekelayo, ezifana ne-lupus, i-rheumatoid arthritis okanye i-antiphospholipid syndrome, umzekelo;
• Izifo ezibangelwa zizifo ezifana ne-HIV, i-hepatitis C, i-syphilis okanye i-malaria, umzekelo;
• Umhlaza.

Abantu abanezifo ezonyusa amathuba e-thrombophilia, njengomhlaza, i-lupus okanye i-HIV, umzekelo, kufuneka balandelwe kuvavanyo lwegazi, ngalo lonke ixesha bebuya nogqirha owenza oku kulandelayo. Ukongeza, ukuthintela i-thrombosis, kubalulekile ukuthatha amanyathelo othintelo, njengokulawula uxinzelelo lwegazi, isifo seswekile kunye ne-cholesterol, ukongeza ekungaleleni okanye ekumeni ixesha elide ngexesha lokuhamba, ngexa lokukhulelwa, i-puerperium okanye isibhedlele.

Ukusetyenziswa kwezicwangcisi zomlomo kufuneka kuthintelwe ngabafazi abasele benomngcipheko okhulayo we-thrombophilia, njengaleyo enexinzelelo lwegazi, isifo seswekile okanye imbali yosapho yotshintsho egazini.

2. Izizathu zofuzo

Oonobangela abaphambili be-thrombophilia yelifa zezi:

• Ukusilela kwee-anticoagulants zendalo emzimbeni, obizwa ngokuba yiprotein C, iprotein S kunye ne-antithrombin, umzekelo;
• Uxinzelelo oluphezulu lwe-homocysteine ​​amino acid;
• Utshintsho kwiiseli ezenza igazi, njengakwi-Leiden factor V;
• Ii-enzyme zegazi ezigqithileyo ezibangela i-clotting, enje nge-VII kunye ne-fibrinogen, umzekelo.

Nangona i-thrombophilia elifa Kwiimeko ezinzima kakhulu, ukusetyenziswa kwamayeza e-anticoagulant kungabonakaliswa ngugqirha wegazi emva kokuvavanya imeko nganye.

Zithini iimviwo ekufuneka zenziwe

Ukufumanisa esi sifo, ugqirha jikelele okanye ugqirha wegazi kufuneka akrokre malunga nembali yeklinikhi kunye nosapho lomntu ngamnye, nangona kunjalo ezinye iimvavanyo ezinje ngokubala kwegazi, iswekile yegazi kunye namanqanaba e-cholesterol anokuyalelwa ukuba aqinisekise kwaye abonise olona nyango lulungileyo.

Xa kukrokrelwa ifa le-thrombophilia, ngakumbi xa iimpawu zinokuphindaphindeka, ukongeza kwezi mvavanyo, idosi yokunqanda igazi ye-enzyme iyacelwa ukuba ivavanye amanqanaba ayo.

Unyango lwenziwa njani

Unyango lwe-thrombophilia lwenziwa ngononophelo ukuthintela i-thrombosis, njengokuphepha ukuma ngxi ixesha elide kuhambo, ukuthatha amayeza e-anticoagulant ngexesha lokuhlala esibhedlele okanye emva kotyando, kwaye ikakhulu, ukulawula izifo ezonyusa umngcipheko wamahlwili, njengokuphakama uxinzelelo lwegazi, isifo seswekile kunye nokutyeba, umzekelo. Kuphela kwiimeko zokugula kakhulu, ukusetyenziswa okungapheliyo kwamachiza anticoagulant kubonisiwe.

Nangona kunjalo, xa umntu sele enempawu ze-thrombophilia, i-vein thrombosis okanye i-pulmonary embolism, kuyacetyiswa ukuba kusetyenziswe iziyobisi zomlomo ze-anticoagulant kwiinyanga ezimbalwa, ezinje ngeHeparin, iWarfarin okanye iRivaroxabana powder, umzekelo. Abasetyhini abakhulelweyo, unyango lwenziwa nge-anticoagulant enesitofu kwaye kufuneka uhlale esibhedlele iintsuku ezimbalwa.

Fumanisa ukuba zeziphi ii-anticoagulants ezisetyenziswa kakhulu kwaye zezantoni.