Isifo se-Milk-alkali

Ubisi lwe-Milk-alkali syndrome yimeko apho kukho inqanaba eliphezulu le-calcium emzimbeni (hypercalcemia). Oku kubangela ukutshintsha komzimba we-asidi / isiseko se-alkaline (i-metabolic alkalosis). Ngenxa yoko, kunokubakho ilahleko ekusebenzeni kwezintso.

I-Milk-alkali syndrome phantse ihlala ibangelwa kukuthatha izongezo ze calcium ezininzi, zihlala zikwimo ye calcium carbonate. I-calcium carbonate yinto eqhelekileyo yokuncedisa i-calcium. Ihlala ithathwa ukuthintela okanye ukunyanga ukulahleka kwethambo (i-osteoporosis). I-calcium carbonate ikwayinto efumaneka kwii-antacids (ezinjengeeTum).

Inqanaba eliphezulu levithamini D emzimbeni, njengokuthatha izongezo, kunokuba nzima kubisi lwealkal syndrome.

I-calcium deposits kwizintso kunye nakwezinye izicubu zingenzeka kwi-milk-alkali syndrome.

Ekuqaleni, imeko ihlala ingenazo iimpawu (asymptomatic). Xa iimpawu zenzeka, zinokubandakanya:

• Emuva, phakathi komzimba, kunye neentlungu ezisezantsi ezisezintso (ezinxulumene namatye ezintso)
• Ukudideka, isimilo esingaqhelekanga
• Ukuqunjelwa
• Uxinzelelo
• Ukuchama kakhulu
• Ukudinwa
• Ukubetha kwentliziyo ngokungaqhelekanga (arrhythmia)
• Isihlunu okanye ukugabha
• Ezinye iingxaki ezinokubangelwa kukusilela kwezintso

I-calcium deposits ngaphakathi kwezicubu zezintso (nephrocalcinosis) inokubonwa kwi:

• X-reyi
• Ukuskena i-CT
• I-Ultrasound

Olunye uvavanyo olusetyenziselwa ukwenza uxilongo lunokubandakanya:

• Amanqanaba e-Electrolyte ukujonga amanqanaba emaminerali emzimbeni
• I-Electrocardiogram (ECG) yokujonga umbane wentliziyo
• I-Electroencephalogram (i-EEG) yokulinganisa ukusebenza kombane kwingqondo
• Izinga lokuhluza leGlomerular (GFR) ukujonga ukuba zisebenza njani izintso
• Inqanaba lecalcium yegazi

Kwiimeko ezinzima, unyango lubandakanya ukunika ulwelo ngomthambo (nge-IV). Ngaphandle koko, unyango lubandakanya ukusela amanzi kunye nokunciphisa okanye ukumisa izongezo zekhalsiyam kunye nee-antacids ezinekhalsiyam. Izongezo zeVitamin D zikwafuna ukunciphisa okanye ukumiswa.

Le meko ihlala ibuyiselwa umva ukuba umsebenzi wezintso uhlala uqhelekile. Amatyala amade okwexeshana angakhokelela kukusilela kwezintso ngokusisigxina okufuna idialysis.

Ezona ngxaki zixhaphakileyo zibandakanya:

• I-calcium ifaka izicubu (calcinosis)
• Ukungaphumeleli kwezintso
• Amatye eentso

Nxibelelana nomboneleli wakho wezempilo ukuba:

• Uthatha ii-calcium ezininzi okanye uhlala usebenzisa ii-antacids eziqulathe ikhalsiyam, ezinje ngeTum. Kuya kufuneka uhlolwe isifo se-alkali syndrome.
• Unazo naziphi na iimpawu ezinokubonisa iingxaki zezintso.

Ukuba usebenzisa i-calcium ene-antacids rhoqo, xelela umboneleli wakho malunga neengxaki zokugaya ukutya. Ukuba uzama ukuthintela i-osteoporosis, sukuthatha ngaphezulu kwe-1.2 yeigram (1200 milligrams) yecalcium ngosuku ngaphandle kokuba uyalelwe ngumboneleli wakho.

Isifo seCalcium-alkali; Isifo seCope; Isifo seBurnett; Hypercalcemia; Ingxaki yeCalcium metabolism

I-Bringhurst FR, iDemay MB, iKronenberg HM. IiHormone kunye nokuphazamiseka kwemetabolism yamaminerali. Ku: UMelmed S, uAuchus RJ, uGoldfine AB, uKoenig RJ, uRosen CJ, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-14. IPhiladelphia, PA: Elsevier; 2020: isahluko 29.

I-DuBose TD. I-alkalosis yeMetabolic. Ku: Gilbert SJ, Weiner DE, ii-eds. Isiseko seSizwe seZintso kwiZifo zeZintso. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 14.