Umhlaza wedlala lengqula - i-medullary carcinoma

I-Medullary carcinoma yedlala lengqula ngumhlaza wedlala lengqula oqala kwiiseli ezikhupha ihomoni ebizwa ngokuba yi-calcitonin. Ezi seli zibizwa ngokuba yi "C" iiseli. I-thyroid gland ikhona ngaphakathi phambi kwentamo yakho engezantsi.

Isizathu se-medullary carcinoma ye-thyroid (MTC) asiyazi. I-MTC inqabile kakhulu. Inokwenzeka ebantwaneni nakubantu abadala.

Ngokungafaniyo nezinye iintlobo zomhlaza wedlala lengqula, i-MTC ayinakufane ibangelwe lonyango lwemitha entanyeni enikwe ukunyanga eminye imihlaza ngexesha lobuntwana.

Zimbini iindlela ze-MTC:

• I-Sporadic MTC, engasebenzi kwiintsapho. Uninzi lweMTCs lubakho ngamaxesha athile. Le fomu ichaphazela abantu abadala abadala.
• I-MTC yelifa, ebaleka kwiintsapho.

Unobungozi obandayo kolu hlobo lomhlaza ukuba unayo:

• Imbali yosapho yeMTC
• Imbali yosapho ye-endocrine neoplasia (MEN)
• Imbali yangaphambili ye-pheochromocytoma, i-mucosal neuromas, i-hyperparathyroidism okanye i-pancreatic endocrine tumors

Ezinye iintlobo zomhlaza we-thyroid zibandakanya:

• I-Anaplastic carcinoma ye-thyroid
• Ithumba lesibindi le-thyroid
• I-papillary carcinoma ye-thyroid
• I-thyroid lymphoma

I-MTC ihlala iqala njengeqhuma elincinci (i-nodule) kwi-thyroid gland. Kukho kwakhona ukuba ne-lymph node ukuvuvukala entanyeni. Ngenxa yoko, iimpawu zingabandakanya:

• Ukudumba kwentamo
• Ukurhabaxa
• Iingxaki zokuphefumla ngenxa yokuncipha kweendlela zomoya
• Khohlela
• Khohlela ngegazi
• Urhudo ngenxa yenqanaba eliphezulu le-calcitonin

Umboneleli wakho wezempilo uya kwenza uvavanyo lomzimba kwaye abuze malunga neempawu zakho kunye nembali yonyango.

Iimvavanyo ezingasetyenziselwa ukuxilonga i-MTC ziquka:

• Uvavanyo lwegazi lweCalcitonin
• Uvavanyo lwegazi lweECA
• Uvavanyo lwemfuzo
• I-biopsy yegilo
• I-Ultrasound ye-thyroid kunye ne-lymph nodes entanyeni
• Ukuskena iPET

Abantu abane-MTC kufuneka bahlolwe ezinye izidlo, ngakumbi i-pheochromocytoma kunye ne-parathyroid tumors kunye ne-parathyroid tumors.

Unyango lubandakanya utyando ukususa i-thyroid gland kunye ne-lymph nodes. Kuba eli lithumba elingaqhelekanga, utyando kufuneka lwenziwe ngugqirha oqheleneyo nolu hlobo lomhlaza kwaye onamava ngokusebenza okufunekayo.

Olunye unyango luya kuxhomekeka kumanqanaba akho e-calcitonin. Ukunyuka kwamanqanaba e-calcitonin kwakhona kunokubonisa ukukhula komhlaza.

• I-Chemotherapy kunye ne-radiation azisebenzi kakuhle kolu hlobo lomhlaza.
• Imitha isetyenziswa kwabanye abantu emva kotyando.
• Unyango ekujoliswe kulo ngokutsha kunokunciphisa ukukhula kwethumba nako. Umboneleli wakho unokukuxelela ngakumbi malunga nezi, ukuba ziyafuneka.

Kufuphi nezihlobo zabantu abafunyaniswe benesimo selifa se-MTC basemngciphekweni wokufumana lo mhlaza kwaye kufuneka baxoxe nababoneleli babo.

Ungaluphelisa uxinzelelo lokugula ngokujoyina iqela lokuxhasa umhlaza. Ukwabelana nabanye abanamava afanayo kunye neengxaki kunokukunceda ungaziva ulilolo.

Uninzi lwabantu abane-MTC baphila ubuncinci iminyaka emi-5 emva kokuxilongwa, kuxhomekeke kwinqanaba lomhlaza. Inqanaba lokusinda leminyaka eli-10 ngama-65%.

Iingxaki zinokubandakanya:

• Umhlaza unwenwela nakwezinye iindawo zomzimba
• Izibilini zeParathyroid zisuswe ngengozi ngexesha lotyando

Tsalela umnikezeli wakho ukuba uneempawu ze-MTC.

Ukuthintela akunakwenzeka. Kodwa, ukwazi imingcipheko yakho, ngakumbi imbali yosapho lwakho, kunokuvumela ukuxilongwa kwangoko kunye nonyango. Kubantu abanembali eyomeleleyo yosapho ye-MTC, ukhetho lokususa i-thyroid gland lunokucetyiswa. Kuya kufuneka uxoxe ngononophelo ngolu khetho nogqirha oqhelene kakhulu nesi sifo.

Idlala lesikhumba - medullary carcinoma; Umhlaza - idlala lengqula (medullary carcinoma); MTC; Idyroid nodule - medullary

• Umhlaza wegciwane le-thyroid-CT scan
• Idlala lengqula

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Kwiwebhusayithi yeZiko loMhlaza weSizwe. Unyango lomhlaza wedlala lengqula (yabantu abadala) (PDQ) -uhlobo lobungcali kwezempilo. www.cancer.gov/types/thyroid/hp/thyroid-kunyanga-pdq. Ukuhlaziywa ngoJanuwari 30, 2020. Ifikeleleke ngo-Matshi 6, 2020.

USmith PW, uHanks LR, uSalomone LJ, uHanks JB. Idlala lengqula. Ku: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, ii-eds. Incwadi yeSabiston yoNyango. Umhla we-20. IPhiladelphia, PA: Elsevier Saunders; Ngo-2017: isahluko 36.

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I-Wells SA Jr, uAsa SL, uDralle H. Izikhokelo zoMbutho weAmerican Thyroid Association kulawulo lwe-medullary thyroid carcinoma. Idlala lengqula. 2015; 25 (6): 567-610. IINKCUKACHA: 25810047 pubmed.ncbi.nlm.nih.gov/25810047/.