Igawuthi

Igawuthi luhlobo lwesifo samathambo. Kwenzeka xa i-uric acid yanda egazini kwaye ibangela ukudumba kumalungu.

Igawuthi ebukhali yimeko ebuhlungu edla ngokuchaphazela ilungu elinye kuphela. Isifo esinganyangekiyo kukuphindaphindwa kwentlungu kunye nokudumba. Amalungu angaphezu kwelinye angachaphazeleka.

Igawuthi ibangelwa kukuba nenqanaba eliphezulu le-uric acid emzimbeni wakho. Oku kunokwenzeka ukuba:

• Umzimba wakho wenza i-uric acid eninzi kakhulu
• Umzimba wakho kunzima ukususa i-uric acid

Xa i-uric acid yakhela kulwelo olujikeleze amalungu (i-synovial fluid), i-uric acid crystals form. Ezi kristali zenza ukuba indibaniselwano idumbe, ibangele iintlungu, ukudumba kunye nobushushu.

Oyena nobangela awaziwa. Igawuthi inokubaleka kwiintsapho. Ingxaki ixhaphake kakhulu emadodeni, kwabasetyhini emva kokuyeka ukuya exesheni, nakubantu abasela utywala. Njengokuba abantu bekhula, igawuthi iya ixhaphaka.

Le meko inokuphinda ikhule kubantu abane:

• Seswekile
• Isifo sezintso
• Ukutyeba kakhulu
• I-Sickle cell anemia kunye nezinye i-anemias
• Ileukemia kunye neminye imihlaza yegazi

Igawuthi ingenzeka emva kokuthatha amayeza aphazamisa ukususwa kwe-uric acid emzimbeni. Abantu abathatha amayeza athile, anjengehydrochlorothiazide kunye nezinye iipilisi zamanzi, banokuba nenqanaba eliphezulu leuric acid egazini.

Iimpawu zesifo esibuhlungu:

• Kwiimeko ezininzi, kuchaphazeleka ilungu elinye okanye amalungu ambalwa. Unyawo olukhulu, idolo, okanye amaqatha amaqatha zihlala zichaphazeleka. Ngamanye amaxesha amalungu amaninzi adumba abe buhlungu.
• Intlungu iqala ngequbuliso, rhoqo ebusuku. Ubuhlungu buhlala buba nzima, buchazwa njengokuphamba, ukutyumza, okanye ukubetha.
• Idibeneyo ibonakala ifudumele kwaye ibomvu. Ihlala ithambile kwaye idumbile (kubuhlungu ukubeka iphepha okanye ingubo ngaphezulu kwayo).
• Kunokubakho ifiva.
• Uhlaselo lunokuhamba ngeentsuku ezimbalwa, kodwa lunokubuya amaxesha ngamaxesha. Ukuhlaselwa okongeziweyo kuhlala kuhlala ixesha elide.

Intlungu kunye nokudumba kuhlala kuhamba emva kohlaselo lokuqala. Abantu abaninzi baya kuba nolunye uhlaselo kwiinyanga ezi-6 ukuya kwezi-12 ezizayo.

Abanye abantu banokuphuhlisa i-gout engapheliyo. Oku kukwabizwa ngokuba yi-gouty arthritis. Le meko inokukhokelela kumonakalo odibeneyo kunye nelahleko yokunyakaza kumalungu. Abantu abane-gout engapheliyo baya kuba neentlungu ezidibeneyo kunye nezinye iimpawu ixesha elininzi.

Iidipozithi zeuric acid zingenza amaqhuma angaphantsi kolusu ujikeleze amalungu okanye ezinye iindawo ezinjengeengqiniba, iincam zeminwe kunye neendlebe. Iqhuma libizwa ngokuba yitophus, lisuka kwisiLatin, elithetha uhlobo lwelitye. ITophi (amaqhuma amaninzi) anokukhula emva kokuba umntu ene-gout iminyaka emininzi. Ezi ziqhuma zinokukhupha izinto ezinobushushu.

Uvavanyo olunokwenziwa lunokubandakanya:

• Uhlalutyo lweSynovial fluid (lubonisa uric acid crystals)
• Uric acid - igazi
• IX-reyi ezidibeneyo (zinokuba yinto eqhelekileyo)
• I-synovial biopsy
• Uric acid - umchamo

Inqanaba le-uric acid egazini ngaphezulu kwe-7 mg / dL (milligrams kwidesilitha nganye) liphezulu. Kodwa, ayinguye wonke umntu onenqanaba eliphezulu le-uric acid ene-gout.

Thatha amayeza ngesi sifo ngokukhawuleza kangangoko unako ukuba uhlaselo olutsha.

Thatha iziyobisi ezichasayo (ii-NSAID) ezinje nge-ibuprofen okanye i-indomethacin xa kuqala iimpawu. Thetha nomboneleli wakho wezempilo malunga nedosi echanekileyo. Uya kudinga iidosi ezomeleleyo kwiintsuku ezimbalwa.

• Iyeza elibizwa ngokuba yi-colchicine linceda ukunciphisa iintlungu, ukudumba kunye nokudumba.
• ICorticosteroids (enje nge-prednisone) nayo inokusebenza kakhulu. Umboneleli wakho unokufaka inaliti edibeneyo kunye ne-steroids yokuphelisa iintlungu.
• Ngokuhlaselwa kwegawuthi kumalungu adibeneyo inokusetyenziswa iyeza elinokutofa elibizwa ngokuba yi-anakinra (Kineret).
• Intlungu ihlala iphela kwiiyure ezili-12 zokuqala unyango. Uninzi lwexesha, zonke iintlungu zihambe ngaphakathi kweeyure ezingama-48.

Kuya kufuneka uthathe amayeza emihla ngemihla anje nge-allopurinol (Zyloprim), febuxostat (Uloric) okanye i-probenecid (Benemid) ukunciphisa izinga le-uric acid egazini lakho. Ukuthoba i-uric acid ibe ngaphantsi kwe-6 mg / dL iyafuneka ukukhusela iidipozithi ze-uric acid. Ukuba une-tophi ebonakalayo, i-uric acid kufuneka ibe ngaphantsi kwe-5 mg / dL.

Ungawafuna la mayeza ukuba:

• Uhlaselwa izihlandlo ezininzi kwakuloo nyaka okanye uhlaselo lwakho lubi kakhulu.
• Unomonakalo kumalungu.
• Unayo tophi.
• Unesifo sezintso okanye amatye ezintso.

Ukutya kunye notshintsho kwindlela yokuphila kunokunceda ukuthintela uhlaselo lwe-gouty:

• Nciphisa utywala, ngakumbi ibhiya (ezinye iwayini zinokuba luncedo).
• Yehla emzimbeni.
• Zilolonge yonke imihla.
• Nciphisa ukutya kwakho inyama ebomvu kunye neziselo ezineswekile.
• Khetha ukutya okusempilweni, okufana neemveliso zobisi, imifuno, amandongomane, iimbotyi, iziqhamo (ezineswekile encinci), kunye neenkozo ezipheleleyo.
• Ikhofi kunye nevithamini C zongeze (zinokunceda abanye abantu).

Unyango olufanelekileyo lokuhlaselwa ngokuqatha kunye nokunciphisa i-uric acid kwinqanaba elingaphantsi kwe-6 mg / dL ivumela abantu ukuba baphile ubomi obuqhelekileyo. Nangona kunjalo, uhlobo olubi lwesifo lunokuqhubela phambili kwi-gout engapheliyo ukuba i-uric acid ephezulu ayinyangwa ngokufanelekileyo.

Iingxaki zinokubandakanya:

• Isifo samathambo esinganyangekiyo.
• Amatye eentso.
• Idiphozithi kwizintso, ekhokelela ekusileleni kwezintso okungapheliyo.

Amanqanaba aphezulu e-uric acid egazini ayanyaniswa nengozi eyandayo yesifo sezintso. Izifundo ziyenziwa ukufumanisa ukuba ukwehlisa i-uric acid kunciphisa umngcipheko wesifo sezintso.

Tsalela umnikezeli wakho ukuba uneempawu zesifo sokuqaqamba kwamalunga okanye isifo segouty.

Usenokungakwazi ukuthintela igawuthi, kodwa usenokukwazi ukunqanda izinto ezibangela iimpawu. Ukuthatha amayeza ukuthoba i-uric acid kunokuthintela ukuvela kwegawuthi. Ixesha elingaphezulu, iidipozithi zakho ze-uric acid ziya kuthi shwaka.

Isifo samathambo esibuhlungu - isifo; Igawuthi - oyingozi; Hyperuricemia; Igawuthi emfiliba; ITophi; IPodagra; Igawuthi - engapheliyo; Igawuthi enganyangekiyo; Igawuthi ebukhali; Isifo samathambo

• Izintso kunye ne-lithotripsy - ukukhutshwa
• Izintso zamatye - ukuzinyamekela
• Izintso zamatye - yintoni oza kuyibuza ugqirha wakho
• Iinkqubo ezisebenzayo zokuchama-ukukhupha

• Iikristale zeUric acid
• Tophi igawuthi ngesandla

Ukutsha kweCM, iWortmann RL. Iimpawu zonyango kunye nonyango lwe-gout. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, ii-eds. Incwadi kaKelley kunye neFirestein yeRheumatology. Ngomhla we-10. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 95.

Edwards NL. Izifo zokufaka i-Crystal. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 273.

UFitzGerald JD, uNeogi T, uChoi HK. Inqaku lokuhlela: sukuvumela ukungakhathali kwe-gout kukhokelele kwi-gouty arthropathy. Isifo samathambo Rheumatol. Ngo-2017; 69 (3): 479-482. IINKCUKACHA: 28002890 www.ncbi.nlm.nih.gov/pubmed/28002890.

Khanna D, Fitzgerald JD, Khanna PP, okqhubekayo. 2012 Ikholeji yaseMelika yezikhokelo zeRheumatology kulawulo lwesifo. Inxalenye yoku-1: iindlela zonyango ezingezizo ezonyango kunye neendlela zonyango ezihambelana ne-hyperuricemia. Ukunyamekelwa kweArthritis Res (Hoboken). Ngo-2012; 64 (10): 1431-1446. IINKCUKACHA: I-23024028 www.ncbi.nlm.nih.gov/pubmed/23024028.

Khanna D, Khanna PP, Fitzgerald JD, okqhubekayo. 2012 Ikholeji yaseMelika yezikhokelo zeRheumatology kulawulo lwesifo. Icandelo 2: unyango kunye ne-antiinfigueatory prophylaxis ye-gouty arthritis ebukhali. Ukunyamekelwa kweArthritis Res (Hoboken). Ngo-2012; 64 (10): 1447-1461. IINKCUKACHA: 23024029 www.ncbi.nlm.nih.gov/pubmed/23024029.

U-Liew JW, uGardner GC. Ukusetyenziswa kwe-anakinra kwizigulana ezibhedlele ezine-arthritis ehambelana nekristale. J Rheumatol. Ngo-2019 ipii: jrheum. 181018. [Epub phambi koshicilelo]. IINKCUKACHA: 30647192 www.ncbi.nlm.nih.gov/m/pubmed/30647192.