IgA vasculitis-Henoch-Schönlein purpura

I-vasculitis ye-IgA sisifo esibandakanya amabala amfusa kulusu, iintlungu ezidibeneyo, iingxaki zesisu, kunye ne-glomerulonephritis (uhlobo lwesifo sezintso). Ikwabizwa ngokuba yiHenoch-Schönlein purpura (HSP).

IgA vasculitis ibangelwa yimpendulo engaqhelekanga yamajoni omzimba. Isiphumo kukudumba kwimithambo yegazi microscopic eluswini. Imithambo yegazi kumalungu, izintso, okanye amathumbu anokuchaphazeleka. Akucaci ukuba kutheni le nto isenzeka.

Isifo esibonakalayo kakhulu kubantwana abaphakathi kweminyaka emi-3 ukuya kweli-15 ubudala, kodwa inokubonakala kubantu abadala. Kuqheleke kakhulu kubafana kunamantombazana. Abantu abaninzi abahlakulela esi sifo babenosulelo oluphezulu lokuphefumla kwiiveki ezidlulileyo.

Iimpawu kunye neempawu ze-IgA vasculitis inokubandakanya:

• Amabala amfusa eluswini (purpura). Oku kwenzeka phantse kubo bonke abantwana abanale meko. Oku kuhlala kwenzeka ngaphezulu kweempundu, imilenze esezantsi, kunye neengqiniba.
• Intlungu zesisu.
• Intlungu edibeneyo.
• Umchamo ongaqhelekanga (usenokungabi nazimpawu).
• Urhudo, ngamanye amaxesha ligazi.
• Imihlathi okanye i-angioedema.
• Isicaphucaphu nokugabha.
• Ukudumba kunye neentlungu kwisikram samakhwenkwe.
• Intloko ebuhlungu.

Umboneleli wezempilo uya kujonga umzimba wakho kwaye ajonge ulusu lwakho. Uvavanyo lomzimba luya kubonisa izilonda zesikhumba (i-purpura, izilonda) kunye nokuthamba ngokudibeneyo.

Uvavanyo lunokubandakanya:

• Uhlalutyo lomchamo kufuneka lwenziwe kuzo zonke iimeko.
• Gcwalisa ubalo lwegazi. Iplatelet inokuba yinto eqhelekileyo.
• Uvavanyo lokuxinana: ezi kufuneka ziqheleke.
• Ulusu lwe-biopsy, ngakumbi kubantu abadala.
• Uvavanyo lwegazi ukukhangela ezinye izizathu zokuvuvukala kwemithambo yegazi, enjenge-systemic lupus erythematosus, i-ANCA-ehambelana ne-vasculitis okanye i-hepatitis.
• Kubantu abadala, kufuneka kwenziwe i-biopsy yezintso.
• Ukulinganisa iimvavanyo zesisu ukuba kukho iintlungu.

Akukho lonyango luthile. Uninzi lweziganeko zihamba zodwa. Intlungu edibeneyo inokuphucula nge-NSAID ezinjenge-naproxen. Ukuba iimpawu azihambi, unokumiselwa amayeza e-corticosteroid anje nge-prednisone.

Esi sifo sihlala siphucula ngokwaso. Isibini kwisithathu sabantwana abane-IgA vasculitis banesiqendu esinye kuphela. Isinye kwisithathu sabantwana sineziqendu ezininzi. Abantu kufuneka babe nokulandelwa kwezonyango okufutshane kwiinyanga ezi-6 emva kweziqendu ukujonga iimpawu zesifo sezintso. Abantu abadala banomngcipheko omkhulu wokuhlaselwa sisifo sezintso esinganyangekiyo.

Iingxaki zinokubandakanya:

• Ukopha ngaphakathi emzimbeni
• Ukuthintela amathumbu (ebantwaneni)
  
• Iingxaki zezintso (kwiimeko ezinqabileyo)

Fowunela umnikezeli wakho ukuba:

• Uphuhlisa iimpawu ze-IgA vasculitis, kwaye zihlala ngaphezulu kweentsuku ezimbalwa.
• Unemibala yomchamo okanye imveliso ephantsi yomchamo emva kwesiqendu.

Immunoglobulin I-vasculitis; I-leukocytoclastic vasculitis; UHenoch-Schönlein purpura; I-HSP

• I-Henoch-Schonlein purpura kwimilenze esezantsi
• UHenoch-Schonlein purpura
• UHenoch-Schonlein purpura
• UHenoch-Schonlein purpura
• UHenoch-Schonlein purpura kunyawo losana
• UHenoch-Schonlein purpura kwimilenze yosana
• UHenoch-Schonlein purpura kwimilenze yosana
• I-Henoch-Schonlein purpura kwimilenze

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U-Lu S, u-Liu D, u-Xiao J, kunye no-al. Thelekisa phakathi kwabantu abadala nabantwana abaneHenoch-Schönlein purpura nephritis. Isilwanyana uNephrol. 2015; 30 (5): 791-796. IINKCUKACHA: 25481021 www.ncbi.nlm.nih.gov/pubmed/25481021.

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