Icandelo le-glomerulosclerosis yecandelo

Icandelo le-glomerulosclerosis eqokelelweyo sisicubu esibomvu kwicandelo lokucoca lezintso. Olu lwakhiwo lubizwa ngokuba yi-glomerulus. I-glomeruli isebenza njengezihluzo ezinceda umzimba ukuba ulahle izinto ezinobungozi. Intso nganye inamawaka glomeruli.

"Okugxilwe kuko" kuthetha ukuba ezinye ii-glomeruli ziye zibe namabala. Ezinye zihlala ziqhelekile. "Icandelo '' lithetha ukuba kuphela yinxalenye yeglomerulus eyonakeleyo.

Unobangela we-glomerulosclerosis egxile kwicandelo le-glomerulosclerosis ihlala ingaziwa.

Le meko ichaphazela abantwana kunye nabantu abadala. Kwenzeka kancinci kancinci kumadoda namakhwenkwe. Kuqheleke ngakumbi kuma-Afrika aseMelika. Icandelo le-glomerulosclerosis egxile kwinqanaba elibangela ukuya kwikota yazo zonke iimeko ze-nephrotic syndrome.

Izizathu ezaziwayo zibandakanya:

• Iziyobisi ezinje ngeheroin, bisphosphonates, anabolic steroids
• Usulelo
• Iingxaki zemfuza ezizuzwe njengelifa
• Ukutyeba kakhulu
• I-Reflux nephropathy (imeko apho umchamo uhlehla umva ukusuka kwisinyi ukuya kwizintso)
• Isifo seSickle cell
• Amanye amayeza

Iimpawu zingabandakanya:

• Umchamo we-foamy (ukusuka kwiprotein engaphezulu kumchamo)
• Ukutya okungafanelekanga
• Ukudumba, okubizwa ngokuba yi-edema ngokubanzi, ukusuka kulwelo olubanjwe emzimbeni
• Ukutyeba kwakho

Umboneleli wezempilo uya kwenza uvavanyo lomzimba. Olu vavanyo lunokubonisa ukudumba kwezicubu (i-edema) kunye noxinzelelo lwegazi. Iimpawu zokungaphumeleli kwezintso (ukungaphumeleli kwezintso) kunye nokugqithisa kwamanzi kunokukhula njengoko imeko iya isiba mandundu.

Uvavanyo lunokubandakanya:

• Isifo sezintso
• Uvavanyo lwezintso (igazi nomchamo)
• Uhlalutyo lomchamo
• I-microscopy yomchamo
• Umchamo protein

Unyango lunokubandakanya:

• Amayeza okunciphisa impendulo yomzimba.
• Amayeza okunciphisa uxinzelelo lwegazi. Amanye ala mayeza ayanceda ekunciphiseni isixa seprotini echithwa ngumchamo.
• Amayeza okususa ulwelo olugqithisileyo (umchamo okanye "ipilisi yamanzi").
• Ukutya okune-sodium ephantsi ukunciphisa ukudumba kunye nokunciphisa uxinzelelo lwegazi.

Injongo yonyango kukulawula iimpawu ze-nephrotic syndrome kunye nokuthintela ukusilela kwezintso okungapheliyo. Ezi zonyango zingabandakanya:

• Amayeza okubulala iintsholongwane ukulawula izifo
• Uthintelo lolwelo
• Ukutya okunamafutha asezantsi
• Ukutya okuncinci okanye okuphakathi
• Izongezo zeVitamin D
• Uxilongo
• Ukutshintshwa kwezintso

Inxalenye enkulu yabantu abane-glomerulosclerosis egxile okanye yecandelo iya kuphuhlisa ukusilela kwezintso okungapheliyo.

Iingxaki zinokubandakanya:

• Ukusilela kwezintso okungapheliyo
• Isifo sokugqibela sezintso
• Usulelo
• Ukungondleki
• Isifo seNephrotic

Fowunela umnikezeli wakho ukuba uphuhlisa iimpawu zale meko, ngakumbi ukuba kukho:

• Ifiva
• Ubuhlungu xa uchama
• Ukuncipha kwemveliso yomchamo

Akukho luthintelo lwaziwayo.

Icandelo le-glomerulosclerosis; I-Focal sclerosis ene-hyalinosis

• Inkqubo yomchamo wamadoda

I-Appel GB, iD'Agati VD. Isiseko kunye nesekondari (ezingezizo ezofuzo) ezibangela ukuqaqamba kunye necandelo le-glomerulosclerosis. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahl. 18.

I-Appel GB, iRadhakrishnan J.Ukuphazamiseka kweGlomerular kunye nephrotic syndromes. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil.Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 121.

IPendergraft WF, uNachman PH, uJennette JC, uFalk RJ. Isifo esisisiseko se-glomerular. Ku: Skorecki K, Taal MW, Chertow GM, Marsden PA, Yu ASL, ii-eds. Brenner kunye noMphathi weZintso. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 32.