Kufunyenwe isiphene somsebenzi weplatelet

Iziphene zomsebenzi weplatelet efumanekayo ziimeko ezithintela ukujija kwezinto egazini ekuthiwa ziiplatelet ekusebenzeni ngendlela ebekufanele ukuba zisebenza ngayo. Igama elithi lifunyenwe lithetha ukuba ezi meko azikho xa kuzalwa.

Ukuphazamiseka kweplatelet kunokuchaphazela inani leeplatelets, ukusebenza kwazo kakuhle, okanye zombini. Ingxaki yeplatelet ichaphazela ukujiya kwegazi okuqhelekileyo.

Ukuphazamiseka okunokubangela iingxaki ekusebenzeni kweplatelet kubandakanya:

• Idiopathic thrombocytopenic purpura (ukuphazamiseka kwegazi apho amajoni omzimba atshabalalisa iiplatelets)
• I-leukemia engapheliyo (umhlaza wegazi oqala ngaphakathi komongo wethambo)
• I-myeloma emininzi (umhlaza wegazi oqala kwiiseli ze-plasma kumongo wethambo)
• I-myelofibrosis yaseprayimari (ukuphazamiseka komongo wethambo apho umongo uthathelwa indawo ziicubu ezibomvu)
• IPolycythemia vera (isifo somongo wethambo esikhokelela kukonyuka okungaqhelekanga kwinani leeseli zegazi)
• I-primary thrombocythemia (ingxaki yomongo wethambo apho umongo uvelisa iiplatelets ezininzi)
• I-thrombotic thrombocytopenic purpura (ingxaki yegazi ebangela ukuba amahlwili egazi enze kwimithambo yegazi encinci)

Ezinye izizathu zibandakanya:

• Ukusilela kwezintso (izintso)
• Amayeza anje nge-aspirin, ibuprofen, amanye amachiza achasene nokudumba, ipenicillin, i-phenothiazines, kunye ne-prednisone (emva kokusetyenziswa kwexesha elide)

Iimpawu zinokubandakanya nayiphi na kwezi zinto zilandelayo:

• Ukuya exesheni okunzima okanye ukopha ixesha elide (ngaphezulu kweentsuku ezintlanu ixesha ngalinye)
• Ukopha ngokungaqhelekanga kwilungu lobufazi
• Igazi kumchamo
• Ukopha phantsi kwesikhumba okanye kwiimisipha
• Ukurhabaxa ngokulula okanye ukhombe amabala abomvu kulusu
• Ukopha emathunjini okubangelwa ligazi, mnyama mnyama, okanye ukulinda ukuhamba kwamathumbu; okanye ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
• Iimpumlo

Uvavanyo olunokwenziwa lubandakanya:

• Umsebenzi wePlatelet
• Ubalo lweplatelet
• PT kunye PTT

Unyango lujolise ekulungiseni unobangela wengxaki:

• Ukuphazamiseka komongo wethambo kuhlala kunyangwa ngegazi okanye kususwe iiplatelet egazini (iplatelet pheresis).
• I-Chemotherapy inokusetyenziselwa ukunyanga imeko ebangela ingxaki.
• Iziphene zomsebenzi wePlatelet ezibangelwa kukusilela kwezintso ziphathwa nge-dialysis okanye ngamayeza.
• Iingxaki zePlatelet ezibangelwa liyeza elithile ziyanyangwa ngokumisa ichiza.

Uninzi lwexesha, ukunyanga unobangela wengxaki kulungisa isiphako.

Iingxaki zinokubandakanya:

• Ukopha okungayeki ngokulula
• I-anemia (ngenxa yokopha kakhulu)

Fowunela umboneleli wakho wezempilo ukuba:

• Ukopha kwaye awazi unobangela
• Iimpawu zakho ziba zibi
• Iimpawu zakho aziphucuki emva kokuba unyangwe ngenxa yesiphene somsebenzi weplatelet

Ukusetyenziswa kwamayeza njengoko kuyalelwe kunokunciphisa umngcipheko weziphene ezinxulumene neziyobisi. Ukunyanga ezinye iingxaki kunokunciphisa umngcipheko. Ezinye iimeko azinakuthintelwa.

Ukufumana ukuphazamiseka kweplatelet esemgangathweni; Ukuphazamiseka okufumanekayo komsebenzi weplatelet

• Ukubumba kwegazi
• Amahlwili egazi

UDiz-Kucukkaya R, uLopez JA. Ukuphazamiseka okufumanekayo komsebenzi weplatelet. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 130.

Iholo JE. I-Hemostasis kunye nokuqina kwegazi. Ku: Iholo JE, ed. Incwadi kaGuyton kunye neHolo yePhysical Physiology. Umhla we-13. IPhiladelphia, PA: Elsevier; 2016: isahluko 37.

UJobe SM, uDi Paola J.Ukuzalwa kunye nokufumana ukuphazamiseka kokusebenza kweplatelet kunye nenombolo. Ku: Amakhitshi CS, Kessler CM, Konkle BA, Streiff MB, Garcia DA, eds. Ukubonisana ngeHemostasis kunye neThrombosis. Ngomhla we-4. IPhiladelphia, PA: Elsevier; I-2019: isahluko 9.