Hyperthermia enobungozi

I-hyperthermia enobungozi (MH) sisifo esibangela ukunyuka okukhawulezileyo kubushushu bomzimba kunye nezihlunu ezinzima zemisipha xa umntu one-MH efumana i-anesthesia ngokubanzi. I-MH idluliselwa kwiintsapho.

IHyperthermia ithetha ubushushu bomzimba obuphezulu. Le meko ayifani ne-hyperthermia evela kungxamiseko lonyango olufana nokubetha kobushushu okanye usulelo.

MH izuzwe njengelifa. Mnye kuphela umzali ekufuneka ephethe esi sifo ukuze umntwana asizuze njengelifa esi sifo.

Inokwenzeka nezinye izifo zemisipha ezizuzwe njengelifa, ezinje nge-multiminicore myopathy kunye nesifo esiphambili.

Iimpawu ze-MH zibandakanya:

• Ukopha
• Umchamo omdaka mnyama (ngenxa yeprotein yemisipha ebizwa ngokuba yi-myoglobin kumchamo)
• Ubuhlungu bemisipha ngaphandle kwesizathu esibonakalayo, njengokuzilolonga okanye ukwenzakala
• Ukuqina kwemisipha kunye nokuqina
• Ukuphakama kubushushu bomzimba ukuya kwi-105 ° F (40.6 ° C) okanye ngaphezulu

I-MH ihlala ifunyanwa emva kokuba umntu enikwe i-anesthesia ngexesha lotyando.

Kunokubakho imbali yosapho ye-MH okanye ukufa okungachazwanga ngexesha lokubulala iintlungu.

Umntu unokuba nesantya sentliziyo esikhawulezayo kwaye esingaqhelekanga rhoqo.

Uvavanyo lwe-MH lunokubandakanya:

• Izifundo zokujija igazi (PT, okanye ixesha leprothrombin; PTT, okanye ixesha le-thromboplastin)
• Iphaneli yekhemistri yegazi, kubandakanya i-CK (creatinine kinase, ephezulu egazini xa kutshatyalaliswa umsipha ngexesha lokugula)
• Ukuvavanywa kwemfuza ukukhangela iziphene kwimfuza enxulunyaniswa nesi sifo
• Imisipha biopsy
• I-myoglobin yomchamo (iproteni yemisipha)

Ngexesha lesiqendu se-MH, iyeza elibizwa ngokuba yi-dantrolene lihlala linikwa. Ukusongela umntu ngengubo yokupholisa kunokunceda ukunciphisa umkhuhlane kunye nomngcipheko weengxaki ezinzima.

Ukugcina umsebenzi wezintso ngexesha lesiqendu, umntu unokufumana ulwelo ngomthambo.

Ezi zibonelelo zinokunika ulwazi oluthe kratya malunga neMH:

• Umbutho we-Hyperthermia oManyeneyo wase-United States- www.mhaus.org
• Umbutho weSizwe woNxunguphalo oluNqabileyo-ararediseases.org/rare-diseases/malignant-hyperthermia
• Isalathiso seKhaya le-NIH yemfuzo- ghr.nlm.nih.gov/condition/malignant-hyperthermia

Iziqendu eziphindaphindwayo okanye ezinganyangekiyo zinokubangela ukusilela kwezintso. Iziqendu ezinganyangekiyo zinokubulala.

Ezi ngxaki zinokwenzeka:

• Ukunqunyulwa
• Ukonakala kwezihlunu zemisipha
• Ukudumba kwezandla kunye neenyawo kunye neengxaki zokuhamba kwegazi kunye nokusebenza kwentliziyo (icandelo lesifo)
• Ukufa
• Ukujiya kwegazi okungaqhelekanga kunye nokopha
• Iingxaki zesingqi sentliziyo
• Ukungaphumeleli kwezintso
• Ukwakhiwa kweasidi kulwelo lomzimba (i-metabolic acidosis)
• Ulwakhiwo lwamanzi emiphungeni
• Izihlunu ezibuthathaka okanye ezikhubazekileyo (myopathy okanye muscular dystrophy)

Ukuba ufuna utyando, xelela ugqirha wakho kunye ne-anesthesiologist ngaphambi kotyando ukuba:

• Uyazi ukuba wena okanye ilungu losapho lwakho unengxaki malunga neanesthesia ngokubanzi
• Uyazi ukuba unembali yosapho ye-MH

Ukusebenzisa amayeza athile kunokuthintela iingxaki ze-MH ngexesha lotyando.

Xelela umboneleli wakho wezempilo ngaphambi kokuba wenze utyando nge-anesthesia ngokubanzi, ukuba wena okanye nabani na kusapho lwakho une-MH.

Ziphephe iziyobisi ezikhuthazayo ezifana necocaine, amphetamine (isantya) kunye novuyo. La machiza anokubangela iingxaki ezifanayo ne-MH kubantu abaqhelekileyo kule meko.

Ukucebisa ngemfuzo kuyacetyiswa kuye nakubani na onembali yosapho ye-myopathy, i-muscular dystrophy, okanye i-MH.

Hyperthermia - enobungozi; Hyperpyrexia - imbi; MH

Umbutho waseMelika woMongikazi Anesthetists. Ukulungela ingxaki kunye nokulungiswa kweengxaki zehyperthermia: ingxelo yengxelo. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. Ukuhlaziywa kuka-Epreli 2018. Kufikeleleke ngoMeyi 6, 2019.

I-Kulaylat MN, iDayton MT. Iingxaki zotyando. Ku: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, ii-eds. Incwadi yeSabiston yoNyango. Umhla we-20. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 12.

UZhou J, uBose D, uAllen PD, iPassah IN. I-hyperthermia enobungozi kunye nokuphazamiseka okunxulumene nemisipha. Ku: Miller RD, ed. I-Anesthesia kaMiller. Ngomhla we-8. IPhiladelphia, PA: Elsevier Saunders; 2015: isahl 43.