Ubukumkani bukaMoses

I-mosaicism yimeko apho iiseli zomntu omnye zinemfuza eyahlukileyo. Le meko inokuchaphazela naluphi na uhlobo lweseli, kubandakanya:

• Iiseli zegazi
• Iqanda kunye neeseli zamadlozi
• Iiseli zolusu

I-mosaicism ibangelwa yimpazamo kwisahlulo seseli kwangoko ekukhuleni kosana olungekazalwa. Imizekelo ye-mosaicism ibandakanya:

• Isifo seMosaic Down syndrome
• Isifo sikaMoses Klinefelter
• Isifo sikaMoses Turner

Iimpawu ziyahluka kwaye kunzima kakhulu ukuqikelela. Iimpawu zisenokungabi qatha ukuba uneeseli eziqhelekileyo nezingaqhelekanga.

Uvavanyo lwe-Genetic lunokuchonga ubungqingili.

Iimvavanyo ziya kufuna ukuphindwaphindwa ukuqinisekisa iziphumo, kunye nokunceda ukumisela uhlobo kunye nobukrakra besifo.

Unyango luya kuxhomekeka kuhlobo nobungqongqo besifo. Unokufuna unyango oluncinci ukuba kuphela ezinye zeeseli aziqhelekanga.

Uqhuba kakuhle kangakanani kuxhomekeke ekubeni ngawaphi amalungu kunye nezicubu ezichaphazelekayo (umzekelo, ingqondo okanye intliziyo). Kunzima ukuqikelela iziphumo zokuba neeseli ezimbini ezahlukeneyo emntwini omnye.

Ngokubanzi, abantu abanenani eliphezulu leeseli ezingaqhelekanga banembono efanayo njengabantu abanesimo esiqhelekileyo sesi sifo (abo banazo zonke iiseli ezingaqhelekanga). Ifom eqhelekileyo ibizwa ngokuba yi-non-mosaic.

Abantu abanenani eliphantsi leeseli ezingaqhelekanga banokuchaphazeleka kancinci. Basenokungafumani ukuba banobumba obude bade bazale umntwana onesimo esingesiyomvelo sesifo. Ngamanye amaxesha umntwana ozelwe engeyiyo-mosaic form akasayi kuphila, kodwa umntwana ozelwe nge-mosaicism uya kuphila.

Iingxaki zixhomekeke ekubeni zingaphi iiseli ezichaphazelekayo kutshintsho lwemfuzo.

Ukuchongwa kobugqwetha kunokubangela ukudideka nokungaqiniseki. Umcebisi ngemfuza unokunceda ekuphenduleni nayiphi na imibuzo malunga nokuxilongwa kunye nokuvavanywa.

Okwangoku akukho ndlela yaziwayo yokuthintela ubugcisa be-mosaicism.

Ubuchwephesha beChromosomal; Ubunjineli beGonadal

UDriscoll DA, uSimpson JL, uHolzgreve W, uOtaño L.Ukuvavanywa kwemvelo kunye nokuxilongwa kwemfuza ngaphambi kokubeleka. Ku: Gabbe SG, Niebyl JR, Simpson JL, et al, ii-eds. I-Obstetrics: Ukukhulelwa okuqhelekileyo kunye neengxaki. Umhla wesi-7. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 10.

INussbaum RL, iMcInnes RR, uWillard HF. Ukuxilongwa ngaphambi kokubeleka kunye nokuvavanywa. Ku: Nussbaum RL, McInnes RR, Willard HF, ii-eds. Thompson kunye no-Thompson Genetics kwiyeza. Ngomhla we-8. IPhiladelphia, PA: Elsevier; 2016: isahluko 17.