Ukukhula kovavanyo lokukhuthaza i-hormone

I-hormone yokukhula (GH) yovavanyo lokukhuthaza ukukala komzimba ukukwazi ukuvelisa i-GH.

Igazi litsalwa amatyeli aliqela. Iisampulu zegazi zithathwa ngomgca we-intravenous (IV) endaweni yokufaka inaliti ngalo lonke ixesha. Uvavanyo luthatha phakathi kweeyure ezimbini ukuya kwezintlanu.

Inkqubo yenziwa ngale ndlela ilandelayo:

• I-IV ihlala ibekwa emthanjeni, ubukhulu becala ingaphakathi kwengqiniba okanye umva wesandla. Isiza siqala ukucocwa ngamayeza okubulala iintsholongwane (i-antiseptic).
• Isampulu yokuqala itsalwa kwakusasa.
• Iyeza linikezelwa ngomthambo. Eli yeza livuselela i-pituitary gland ukukhupha i-GH. Amayeza aliqela ayafumaneka. Umboneleli wezempilo uya kuthatha isigqibo sokuba leliphi iyeza elilungileyo.
• Iisampulu zegazi ezongezelelweyo zitsaliwe kwiiyure ezimbalwa ezizayo.
• Emva kokuba kuthathwe isampulu yokugqibela, umgca we-IV uyasuswa. Uxinzelelo lusetyenziswa ukunqanda ukopha.

Sukutya iiyure ezili-10 ukuya kwezi-12 phambi kovavanyo. Ukutya ukutya kunokutshintsha iziphumo zovavanyo.

Amanye amayeza anokuchaphazela iziphumo zovavanyo. Buza umboneleli wakho ukuba ngaba uyekile ukuthatha nawaphi na amayeza akho phambi kovavanyo.

Ukuba umntwana wakho uza kulwenza olu vavanyo, cacisa ukuba luza kuva njani uvavanyo. Unokufuna ukubonisa kudoli. Okona umntwana wakho eyazi kakuhle into eza kwenzeka kunye nenjongo yenkqubo, kuya kuthi xibilili ixhala.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva ngathi batyhafile okanye batyhafile. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo luhlala lusenziwa ukufumanisa ukuba ukusilela kwehommone yokukhula (ukusilela kwe-GH) kubangela ukukhula okucothayo.

Iziphumo eziqhelekileyo zibandakanya:

• Ixabiso eliqhelekileyo lokuphakama, ubuncinci i-10 ng / mL (10 µg / L)
• Ukungapheli, i-5 ukuya kwi-10 ng / mL (5 ukuya kwi-10 µg / L)
• Engaqhelekanga, 5 ng / mL (5 µg / L)

Ixabiso eliqhelekileyo lilawula ukusilela kwe-hGH. Kwezinye iilebhu, inqanaba eliqhelekileyo li-7 ng / mL (7 µg / L).

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Ukuba olu vavanyo aluphakamisi amanqanaba e-GH, kukho isixa esincitshisiweyo se-hGH esigcinwe kwindawo yangaphandle.

Kubantwana, oku kukhokelela ekuswelekeni kweGH. Kubantu abadala, inokunxulunyaniswa nokusilela kwe-GH yabantu abadala.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukugqobhoza okuninzi ukufumana imithambo
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Amayeza avuselela i-pituitary ngexesha lovavanyo anokubangela iziphumo ebezingalindelekanga. Umboneleli unokukuxelela ngakumbi malunga noku.

Uvavanyo lweArginine; Uvavanyo lweArginine-GHRH

• Ukukhula kovavanyo lokukhuthaza i-hormone

IAlatzoglou KS, iDattani MT. Ukukhula kwehomoni ekukhuleni ebantwaneni. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 23.

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

IPatterson BC, iFelner EI. Hypopituitarism. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahluko 573.