Uvavanyo lwe-ALP isoenzyme

I-alkaline phosphatase (ALP) yi-enzyme efumaneka kwizicubu zomzimba ezininzi ezinjengesibindi, imijelo yenyongo, ithambo namathumbu. Kukho iindlela ezahlukeneyo ze-ALP ebizwa ngokuba yi-isoenzymes. Ubume be-enzyme buxhomekeke ekubeni iveliswa phi emzimbeni. Olu vavanyo luhlala lusetyenziselwa ukuvavanya i-ALP eyenziwe kwizicubu zesibindi kunye namathambo.

Uvavanyo lwe-ALP isoenzyme luvavanyo lweelebhu olulinganisa inani leentlobo ezahlukeneyo ze-ALP egazini.

Uvavanyo lwe-ALP luvavanyo olunxulumene noko.

Isampulu yegazi iyafuneka. Uninzi lwexesha igazi litsalwa kumthambo ngaphakathi kwengqiniba okanye ngasemva kwesandla.

Akufuneki utye okanye usele nantoni na iiyure ezili-10 ukuya kwezi-12 phambi kovavanyo, ngaphandle kokuba umboneleli wakho wezempilo ukuxelela ukuba wenze njalo.

Amayeza amaninzi anokuphazamisa iziphumo zovavanyo lwegazi.

• Umboneleli wakho uya kukuxelela ukuba ngaba ufuna ukuyeka ukuthatha nawaphi na amayeza phambi kokuba wenze olu vavanyo.
• SUKUYEKE okanye utshintshe amayeza akho ungakhange uthethe nomboneleli wakho kuqala.

Unokuziva iintlungu okanye ulwamvila xa kufakwa inaliti. Unokuziva ubethwa sisiza emva kokuba kuthathwe igazi.

Xa iziphumo zovavanyo ze-ALP ziphezulu, unokufuna ukuba ube novavanyo lwe-ALP isoenzyme. Olu vavanyo luya kunceda ekuchongeni ukuba leliphi ilungu lomzimba elibangela amanqanaba aphezulu e-ALP.

Olu vavanyo lunokusetyenziselwa ukuxilonga okanye ukubeka iliso:

• Isifo samathambo
• Isibindi, i-gallbladder, okanye isifo se-bile
• Intlungu esiswini
• Isifo separathyroid
• Ukusilela kweVitamin D

Kungenziwa kwakhona ukujonga ukusebenza kwesibindi kunye nokujonga indlela amayeza owathathayo anokuchaphazela ngayo isibindi sakho.

Ixabiso eliqhelekileyo lenani elipheleleyo le-ALP ngama-44 ukuya kuma-147 eeyunithi zamanye amazwe ilitha nganye (IU / L) okanye i-0.73 ukuya kwi-2.45 ye-microkatal ilitha nganye (atkat / L). Uvavanyo lwe-ALP isoenzyme lunokuba namaxabiso ahlukeneyo aqhelekileyo.

Abantu abadala banamanqanaba asezantsi e-ALP kunabantwana. Amathambo asakhulayo avelisa amanqanaba aphezulu e-ALP. Ngexesha lokukhula okuthile, amanqanaba anokuphakama njenge-500 IU / L okanye i-835 µKat / L. Ngesi sizathu, uvavanyo alwenziwa kubantwana, kwaye iziphumo ezingaqhelekanga zibhekisa kubantu abadala.

Iziphumo zovavanyo lwe-isoenzyme zingabonisa ukuba ukonyuka kukwi "bone" ALP okanye "isibindi" ALP.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Umzekelo ongentla ubonakalisa uluhlu oluqhelekileyo lwemilinganiselo yeziphumo zolu vavanyo. Ezinye iilabhoratri zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo.

Amanqanaba aphezulu e-ALP aphezulu kunesiqhelo:

• Uthintelo lweBiliary
• Isifo samathambo
• Ukutya ukutya okunamafutha ukuba unohlobo lwegazi O okanye uB
• Ukuphilisa ukwaphuka
• Hepatitis
• Hyperparathyroidism
• Ileukemia
• Isifo sesibindi
• KwiLymphoma
• Amathumba amathambo e-Osteoblastic
• Osteomalacia
• Isifo sePaget
• Iirockets
• I-Sarcoidosis

Amanqanaba asezantsi kunesiqhelo e-ALP:

• Hypophosphatasia
• Ukungondleki
• Ukusilela kweeproteni
• Isifo sikaWilson

Amanqanaba aphakame kancinci kunesiqhelo ayinakuba yingxaki ngaphandle kokuba kukho ezinye iimpawu zesifo okanye ingxaki yezonyango.

Uvavanyo lwealkaline phosphatase isoenzyme

• Uvavanyo lwegazi

I-Berk PD, iKorenblat KM. Indlela eya kwisigulana esine-jaundice okanye iimvavanyo zesibindi ezingaqhelekanga. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahl. 147.

UFogel EL, uSherman S. Izifo zenyongo kunye nemibhobho yenyongo. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 155.

UMartin P. Indlela eya kwisigulana esinesifo sesibindi. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 146.

I-Weinstein RS. Osteomalacia kunye neerickets. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 244.