Uvavanyo lwegazi lwe-LDH isoenzyme

Uvavanyo lwe-lactate dehydrogenase (LDH) isoenzyme lujonga ukuba zingakanani iintlobo ze-LDH ezisegazini.

Isampulu yegazi iyafuneka.

Umboneleli wezempilo angakuxelela ukuba uyeke okwethutyana amayeza athile phambi kovavanyo.

Iziyobisi ezinokunyusa imilinganiselo ye-LDH zibandakanya:

• Iintlungu
• I-Aspirin
• Colchicine
• Clofibrate
• Cocaine
• Ifluorides
• Mithramycin
• Iziyobisi
• IProcainamide
• Iingxelo
• IiSteroids (glucocorticoids)

SUKUYEKE ukuthatha nawaphi na amayeza ngaphambi kokuba uthethe nomboneleli wakho.

Xa kufakwa inaliti ukutsala igazi, abanye abantu beva iintlungu kancinci. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

I-LDH yi-enzyme efumaneka kwizicubu zomzimba ezinjengentliziyo, isibindi, izintso, umsipha wamathambo, ingqondo, iiseli zegazi kunye nemiphunga. Xa izicwili zomzimba zonakalisiwe, i-LDH ikhutshelwa egazini.

Uvavanyo lwe-LDH lunceda ukumisela indawo yomonakalo womzimba.

I-LDH ikhona kwiifom ezintlanu, ezahluke kancinci kubume.

• I-LDH-1 ifumaneka ikakhulu kwimisipha yentliziyo nakwiiseli ezibomvu zegazi.
• I-LDH-2 igxile kwiiseli ezimhlophe zegazi.
• I-LDH-3 iphezulu emiphungeni.
• I-LDH-4 iphezulu kwizintso, i-placenta, kunye ne-pancreas.
• I-LDH-5 iphezulu esibindini nakwimisipha yamathambo.

Zonke ezi zinto zinokulinganiswa egazini.

Amanqanaba e-LDH aphezulu kunesiqhelo anokucebisa:

• I-anemia yeHemolytic
• Uxinzelelo lwegazi
• I-mononucleosis echaphazelekayo
• I-ischemia yamathumbu (ukusilela kwegazi) kunye ne-infarction (ukufa kwethishu)
• Ischemic cardiomyopathy
• Isifo sesibindi njenge-hepatitis
• Ukufa komzimba
• Ukulimala kwemisipha
• Isihlunu semisipha
• Ipancreatitis
• Ukufa komzimba
• Ukubetha

Akukho mngcipheko wokuthathwa kwegazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

LD; LDH; I-Lactic (lactate) dehydrogenase isoenzymes

• Uvavanyo lwegazi

ICarty RP, iPincus MR, uSarafraz-Yazdi E.I-enzymology yeklinikhi. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 20.

IChernecky CC, iBerger BJ. Lactate dehydrogenase (LD) isoenzymes. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 702-703.