Iapolipoprotein CII

I-Apolipoprotein CII (apoCII) yiprotein efumaneka kumaqhekeza amakhulu enqatha afunxwa sisisu sesisu. Ikwafumaneka kwi-lipoprotein (VLDL) ephantsi kakhulu, eyenziwe ubukhulu becala i-triglycerides (uhlobo lwamafutha egazini lakho).

Eli nqaku lixoxa ngovavanyo olusetyenzisiweyo ukukhangela i-apoCII kwisampulu yegazi lakho.

Isampulu yegazi iyafuneka.

Unokuxelelwa ukuba ungatyi okanye usele nantoni na iiyure ezi-4 ukuya kwezi-6 phambi kovavanyo.

Xa inaliti ifakwa ukutsala igazi, ungaziva zintlungu, okanye kukuhlaba nje okanye ukuhlaba. Emva koko, kunokubakho ukubetheka apho inaliti yafakwa khona.

Imilinganiselo ye-ApoCII inokunceda ukumisela uhlobo okanye unobangela wamafutha aphezulu egazi. Akucaci ukuba ngaba iziphumo zovavanyo ziluphucula na unyango. Ngenxa yoku, uninzi lweenkampani zeinshurensi yezempilo aziyi kuhlawula kuvavanyo. Ukuba awunayo i-cholesterol ephezulu okanye isifo senhliziyo okanye imbali yentsapho yale miqathango, olu vavanyo alunakucetyiswa kuwe.

Uluhlu oluqhelekileyo ngu-3 ukuya ku-5 mg / dL. Nangona kunjalo, iziphumo ze-apoCII zihlala zixelwa njengangoku okanye ezingekhoyo.

Imizekelo engentla yimilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Amanqanaba aphezulu e-apoCII anokubangelwa yimbali yosapho yokunqongophala kwe-lipoprotein lipase. Le yimeko apho umzimba ungawaphuli amafutha ngokwesiqhelo.

Amanqanaba e-ApoCII ayabonakala nakubantu abanemeko enqabileyo ebizwa ngokuba kukusilela kwe-apoprotein ye-CII yosapho. Oku kubangela isifo se-chylomicronemia, enye imeko apho umzimba ungaphuli mafutha ngesiqhelo.

Iingozi ezinxulumene nokutsalwa kwegazi zincinci kodwa zinokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Imilinganiselo ye-Apolipoprotein inokubonelela ngeenkcukacha ezithe kratya malunga nomngcipheko wesifo sentliziyo, kodwa ixabiso elongeziweyo lolu vavanyo ngaphaya kwepaneli ye-lipid alaziwa.

I-ApoCII; Iapoprotein CII; I-ApoC2; Ukusilela kweLipoprotein lipase - apolipoprotein CII; Isifo seChylomicronemia - apolipoprotein CII

• Uvavanyo lwegazi

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UGenest J, uLibby P.Lipoprotein ukuphazamiseka kunye nesifo sentliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 48.

Ukukhumbula i-AT, i-Towerspring TD, iWarnick GR. Lipids, lipoproteins, apolipoproteins, kunye nezinye izinto ezinobungozi benhliziyo. Ku: Rifai N, ed. I-Tietz yeNcwadi yeKlinikhi yeKhemistry kunye neDiagnostics yeMolekyuli. Umhla wesi-6. ISt Louis, MO: Elsevier; I-2018: isahluko 34.

URobinson JG. Ukuphazamiseka kwemetabolism yelipid. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl. 195.