Antimitochondrial omzimba

Iintsholongwane ze-Antimitochondrial (AMA) zizinto (izilwa-buhlungu) ezenza ngokuchasene ne-mitochondria. I-mitochondria yinxalenye ebalulekileyo yeeseli. Ngumthombo wamandla ngaphakathi kwiiseli. Ezi zinceda iiseli zisebenze ngokufanelekileyo.

Eli nqaku lixoxa ngovavanyo lwegazi olusetyenziselwa ukulinganisa isixa se-AMA egazini.

Isampulu yegazi iyafuneka. Ihlala ithathwa emthanjeni. Inkqubo ibizwa ngokuba yi-venipuncture.

Umboneleli wakho wezempilo angakuxelela ukuba ungatyi okanye usele nantoni na ukuya kuthi ga kwiiyure ezi-6 ngaphambi kovavanyo (amaxesha amaninzi ubusuku bonke).

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye banokuziva ngathi batyhafile okanye batyhafile. Emva koko, kunokubakho ukuthotywa okuthile.

Unokulufuna olu vavanyo ukuba uneempawu zomonakalo wesibindi. Olu vavanyo luhlala lusetyenziselwa ukuxilonga i-biliary cholangitis ephambili, eyayibizwa ngokuba yi-cirrhosis (PBC) yokuqala.

Uvavanyo lunokusetyenziselwa ukuxelela umahluko phakathi kwe-cirrhosis enxulumene nenkqubo ye-bile kunye neengxaki zesibindi ngenxa yezinye izizathu ezinje ngokubhloka, i-hepatitis yentsholongwane, okanye i-cirrhosis enxilisayo.

Ngokwesiqhelo, akukho zintsholongwane zikhoyo.

Olu vavanyo lubalulekile ekuchongeni i-PBC. Phantse bonke abantu abanale meko baya kuvavanywa benesifo. Kunqabile ukuba umntu ngaphandle kwale meko uya kuba neziphumo ezilungileyo. Nangona kunjalo, abanye abantu abaneemvavanyo ezilungileyo ze-AMA kwaye akukho namnye umqondiso wesifo sesibindi onokuthi uqhubele phambili kwi-PBC ngokuhamba kwexesha.

Rhoqo, iziphumo ezingaqhelekanga zinokufunyanwa ngenxa yezinye iintlobo zesifo sesibindi kunye nezifo ezizimele.

Iingozi zokutsalwa kwegazi zincinci kodwa zinokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

• Uvavanyo lwegazi

I-Beuers U, iGershwin ME, iGish RG, et al. Ukutshintsha igama lokuchazwa kwe-PBC: Ukusuka kwi-'cirrhosis 'ukuya kwi' cholangitis '. Iiklinikhi Res Hepatol Gastroenterol. 2015; 39 (5): e57-e59. IINKCUKACHA: 26433440 www.ncbi.nlm.nih.gov/pubmed/26433440.

IChernecky CC, iBerger BJ. A. Kwi: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 84-180.

I-Eaton JE, uLindor KD. I-cirrhosis yamabanga aphantsi. Ku: UFeldman M, uFriedman LS, uBrandt LJ, ii-eds. Sleisenger kunye neFordtran's Amathumbu kunye nezifo zesibindi: iPathophysiology / Diagnosis / Management. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 91.

I-Kakar S. yaseprayimari ye-biliary cholangitis. Ku: Saxena R, ed. I-Hepatic Pathology esebenzayo: Indlela yokuChonga. Ngomhla wesi-2. IPhiladelphia, PA: Elsevier; I-2018: isahluko 26.

UZhang J, uZhang W, uLeung PS, et al. Ukuqhubekeka kokusebenza kweeseli ze-B ezizenzekelayo kwi-cirrhosis ephambili. Isifo seHepatology. Ngo-2014; 60 (5): 1708-1716. IINKCUKACHA: 25043065 www.ncbi.nlm.nih.gov/pubmed/25043065.