Uvavanyo lwegazi lweMethylmalonic acid

Uvavanyo lwegazi lwe-methylmalonic acid lilinganisa inani le-methylmalonic acid egazini.

Isampulu yegazi iyafuneka.

Akukho lungiselelo lukhethekileyo luyimfuneko.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukuphazamiseka okanye ukugruzuka okuncinci. Oku kuya kuhamba kungekudala.

I-Methylmalonic acid yinto eveliswayo xa iiproteni, ezibizwa ngokuba zii-amino acid, emzimbeni zisonakala.

Umboneleli wezempilo unokuyalela olu vavanyo ukuba ngaba kukho iimpawu ezithile zokuphazamiseka kwemfuzo, ezinje nge-methylmalonic acidemia. Ukuvavanywa kwesi sifo kuhlala kwenziwa njengenxalenye yovavanyo lokuzalwa ngokutsha.

Olu vavanyo lunokwenziwa nolunye uvavanyo ukujonga ukusilela kwe-vitamin B12.

Amaxabiso aqhelekileyo zi-0.07 ukuya kwi-0.27 micromoles kwilitha nganye.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Ixabiso elingaphezulu kweqhelekileyo linokubangelwa kukunqongophala kukavithamini B12 okanye imethylmalonic acidemia.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Ukopha kakhulu
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

• Uvavanyo lwegazi

UAntony AC. Iimpawu zeMegaloblastic. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 39.

I-Elghetany MT, i-Schexneider KI, i-Banki K.Ukuphazamiseka kwe-Erythrocytic. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 32.