Uvavanyo lomchamo lwe-5-HIAA

I-5-HIAA luvavanyo lomchamo olulinganisa isixa se-5-hydroxyindoleacetic acid (5-HIAA). I-5-HIAA yimveliso yokwahluka kwehomoni ebizwa ngokuba yi-serotonin.

Olu vavanyo luxelela ukuba ingakanani i-5-HIAA eyenziwa ngumzimba. Ikwayindlela yokulinganisa ukuba ingakanani i-serotonin esemzimbeni.

Isampuli yomchamo weeyure ezingama-24 iyafuneka. Uya kudinga ukuqokelela umchamo wakho ngaphezulu kweeyure ezingama-24 kwisitya esinikezwe elebhu. Umboneleli wakho wezempilo uya kukuxelela ukuba ungakwenza njani oku. Landela imiyalelo ngokuchanekileyo.

Umboneleli wakho uya kukuyalela, ukuba kukho imfuneko, uyeke ukuthatha amayeza anokuphazamisa uvavanyo.

Amayeza anokunyusa imilinganiselo ye-5-HIAA ibandakanya i-acetaminophen (Tylenol), i-acetanilide, i-phenacetin, i-glyceryl guaiacolate (efumaneka kwisiraphu ezininzi zokukhohlela), i-methocarbamol kunye ne-reserpine.

Amayeza anokunciphisa imilinganiselo ye-5-HIAA ibandakanya i-heparin, isoniazid, levodopa, monoamine oxidase inhibitors, methenamine, methyldopa, phenothiazines, kunye ne-tricyclic antidepressants.

Uya kuxelelwa ukuba ungatyi ukutya okuthile kwiintsuku ezi-3 phambi kovavanyo. Ukutya okunokuphazamisa imilinganiselo ye-5-HIAA kubandakanya i-plums, iipinapile, iibhanana, isitshalo seqanda, iitumato, iiavokhado kunye newelnuts.

Uvavanyo lubandakanya kuphela ukuchama okuqhelekileyo, kwaye akukho kungonwabi.

Olu vavanyo lilinganisa inqanaba le-5-HIAA kumchamo. Kuhlala kusenziwa ukufumana amathumba athile kwindawo yokugaya ukutya (i-carcinoid tumors) kunye nokulandela imeko yomntu.

Uvavanyo lomchamo lungasetyenziselwa ukuxilonga isifo esibizwa ngokuba yi-systemic mastocytosis kunye nezinye izicubu zehomoni.

Uluhlu oluqhelekileyo ngu-2 ukuya ku-9 mg / 24h (10.4 ukuya ku-46.8 µmol / 24h).

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Iziphumo ezingaqhelekanga zinokubangelwa:

• Iimvumi zenkqubo ye-endocrine okanye i-carcinoid tumors
• Ukwanda kweeseli zomzimba ezibizwa ngokuba ziiseli zemast kwizitho ezininzi (inkqubo yemastocytosis)

Akukho bungozi kolu vavanyo.

HIAA; 5-hydroxyindole acetic acid; Imetabolite yeSerotonin

IChernecky CC, iBerger BJ. H. Kwi: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. IPhiladelphia, PA: Elsevier Saunders; Ngo-2013: 660-661.

I-Wolin EM, iJensen RT. Amathumba e-Neuroendocrine. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 219.