I-Factor IX yolingo

Inqaku le-IX luvavanyo lwegazi olulinganisa umsebenzi we-IX. Le yenye yeeproteni emzimbeni ezinceda i-clot yegazi.

Isampulu yegazi iyafuneka.

Kusenokufuneka uyeke ukuthatha amayeza athile phambi kolu vavanyo. Umboneleli wakho wezempilo uya kukuxelela ukuba zeziphi.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukutyumza kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo lusetyenziselwa ukufumana unobangela wokopha kakhulu (ukuncipha kwegazi). Okanye, inoku-odolwa ukuba ilungu losapho liyaziwa ngokuba ne-hemophilia B. Uvavanyo lunokwenziwa kwakhona ukubona ukuba lusebenza kakuhle kangakanani unyango lwe-hemophilia B.

Ixabiso eliqhelekileyo ngama-50% ukuya kuma-200% olawulo lwelebhu okanye ixabiso lesalathiso.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo yeziphumo zolu vavanyo.

Ukuncipha komsebenzi we-IX unokunxulunyaniswa:

• IHemophilia B (ukuphazamiseka kwegazi okubangelwa kukungabikho kwegazi ekunqandeni igazi IX)
• Ukuphazamiseka apho iiproteni ezilawula ukujiya kwegazi ziye zisebenze ngakumbi (zisasazwe intravascular coagulation)
• I-fat malabsorption (ayifunisi amanqatha ngokwaneleyo ekudleni kwakho)
• Isifo sesibindi (njenge-cirrhosis)
• Ukunqongophala kukaVitamin K
• Ukuthatha abacoci gazi

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye, kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Olu vavanyo luhlala lusenziwa kubantu abaneengxaki zokopha. Umngcipheko wokopha kakhulu ungaphezulu kancinci kunabantu ngaphandle kweengxaki zokopha.

Uvavanyo lweKrisimesi; Iserum factor IX; Into yeHemophilic B; Icandelo leplasma thromboplastin; I-PTC

UCarcao M, Moorehead P, uLillicrap D.Hemophilia A kunye no-B Ku: Hoffman R, Benz EJ, Silberstein LE, et al, eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 135.

IChernecky CC, iBerger BJ. I-Factor IX (into yeKrisimesi, into ebophayo B, icandelo leplasma thromboplastin, i-PTC) -igazi. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 505-506.

Uvavanyo lweLabhoratri yesifo se-hemostatic kunye ne-thrombotic. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 129.