Uvavanyo lwegazi lweParathyroid (PTH)

Uvavanyo lwe-PTH lulinganisa inqanaba lehomoni yeparathyroid egazini.

I-PTH imele ihomoni yeparathyroid. Yiprotini hormone ekhutshwa yindlala yeparathyroid.

Uvavanyo lwaselebhu lunokwenziwa ukulinganisa isixa se-PTH egazini lakho.

Isampulu yegazi iyafuneka.

Buza umboneleli wakho wezempilo ukuba ngaba uyekile ukutya okanye ukusela ixesha elithile ngaphambi kovavanyo. Rhoqo, awuzukufuna ukuzila ukutya okanye uyeke ukusela.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukutyumza kancinci. Oku kuya kuhamba kungekudala.

I-PTH ikhutshwa ngamadlala e-parathyroid. Iincindi ezi-4 ezincinci ze-parathyroid zibekwe entanyeni, kufutshane okanye ziqhotyoshelwe kwicala elingasemva le-thyroid gland. Idlala lengqula lisentanyeni, ngasentla nje apho iithambo zekhola zakho zidibana embindini.

I-PTH ilawula i-calcium, i-phosphorus, kunye ne-vitamin D kumanqanaba egazi. Kubalulekile ukulawula ukukhula kwethambo. Umboneleli wakho unoku-odola olu vavanyo ukuba:

• Unenqanaba eliphezulu le-calcium okanye inqanaba eliphantsi le-phosphorus egazini lakho.
• Unesifo samathambo esomeleleyo esingenakucaciswa okanye esingayiphenduliyo unyango.
• Unesifo sezintso.

Ukukunceda ukuqonda ukuba i-PTH yakho iqhelekile, umboneleli wakho uya kulinganisa i-calcium yakho yegazi ngaxeshanye.

Amaxabiso aqhelekileyo ziipikogram ezili-10 ukuya kwezingama-55 ngeemililitha (pg / mL).

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Ixabiso le-PTH kuluhlu oluqhelekileyo lisenokungalunganga xa amanqanaba e-serum calcium ephezulu. Thetha nomboneleli wakho malunga nesiphumo sakho.

Inqanaba eliphezulu kuneliqhelekileyo linokwenzeka nge:

• Ukuphazamiseka okwandisa i-phosphate okanye amanqanaba e-phosphorus egazini, njengesifo sexesha elide (esingapheliyo) sesifo sezintso
• Ukusilela komzimba ukuphendula kwi-PTH (pseudohypoparathyroidism)
• Ukungabikho kwe-calcium, enokubangelwa kukungayityi ngokwaneleyo i-calcium, ungafaki i-calcium emathunjini, okanye uphulukane ne-calcium eninzi kumchamo wakho
• Ukukhulelwa okanye ukuncancisa (ingaqhelekanga)
• Ukudumba kwiincindi zamadlala zokuzibulala, ezibizwa ngokuba yi-primaryparparparadroidism
• Amathumba kwilungu leparathyroid, elibizwa ngokuba yiadenomas
• Ukuphazamiseka kweVitamin D, kubandakanya nokukhanya kwelanga ngokwaneleyo kubantu abadala kunye neengxaki zokufunxa, ukwehla, kunye nokusebenzisa ivithamin D emzimbeni

Inqanaba elisezantsi kuneliqhelekileyo linokwenzeka nge:

• Ukususwa ngengozi kwamadlala okubambela parroidroid ngexesha lotyando lwe-thyroid
• Ukutshatyalaliswa ngokuzenzekelayo kwe-parathyroid gland
• Umhlaza oqala kwelinye ilungu lomzimba (njengesifuba, imiphunga, okanye ikholon) kwaye usasazeke kwithambo
• I-calcium eyongezelelweyo ngaphezulu kwexesha elide ihlala ivela kwi-calcium okanye i-antacids ezithile, eziqukethe i-calcium carbonate okanye i-sodium bicarbonate (baking soda)
• Izibilini zeParathyroid azivelisi i-PTH eyaneleyo (i-hypoparathyroidism)
• Amanqanaba asezantsi wemagniziyam egazini
• Ukutshiswa ngamayeza kwiincindi ze-parathyroid
• Sarcoidosis kunye nesifo sephepha
• Ukutya okungaphezulu kwe-vitamin D

Eminye imiqathango ekunga-odolwa kuyo uvavanyo ibandakanya:

• Uninzi lwe-endocrine neoplasia (MEN) I
• Uninzi lwe-endocrine neoplasia (MEN) II

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukugqobhoza okuninzi ukufumana imithambo
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

IParathormone; I-Parathormone (PTH) yeemolekyuli ezingaguqukiyo; I-PTH efanelekileyo; Hyperparathyroidism - uvavanyo lwegazi lwe-PTH; Hypoparathyroidism -Uvavanyo lwegazi lwe-PTH

I-Bringhurst FR, iDemay MB, iKronenberg HM. IiHormone kunye nokuphazamiseka kwemetabolism yamaminerali. Ku: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-13. IPhiladelphia, PA: Elsevier; I-2016: isahluko 28.

IKlemm KM, uKlein MJ. Iimpawu zebhayoloji zeethambo metabolism. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 15.