Ukufakelwa kwe-Fecal microbiota
I-Fecal microbiota transplantation (FMT) inceda ukubuyisela ezinye zeentsholongwane "ezimbi" zekolon yakho kunye neebhaktheriya "ezilungileyo". Inkqubo inceda ukubuyisela iintsholongwane ezilungileyo ezibuleweyo okanye ezinqunyelwe kukusetyenziswa kwee-antibiotics. Ukubuyisela oku kulungelelana kwikholoni kwenza kube lula ukulwa nosulelo.
I-FMT ibandakanya ukuqokelela isitulo kumnikeli ophilileyo. Umboneleli wakho wezempilo uya kukucela ukuba uchonge umnikeli. Uninzi lwabantu lukhetha ilungu losapho okanye umhlobo osondeleyo. Umnikeli akufuneki ukuba usebenzise i-antibiotics kwiintsuku ezi-2 ukuya kwezi-3 ezidlulileyo. Baza kuvavanyelwa naluphi na usulelo egazini okanye esitulweni.
Nje ukuba kuqokelelwe, isitulo somnikeli sixutywe namanzi anetyuwa kwaye sihluziwe. Umxube we-stool ugqithiselwa kwindlela yakho yokugaya (ikholoni) ngombhobho ohamba nge-colonoscope (ityhubhu encinci, eguqukayo kunye nekhamera encinci). Iibhaktheriya ezilungileyo zinokungeniswa emzimbeni ngendlela yetyhubhu engena esiswini ngomlomo. Enye indlela kukuginya i-capsule equlathe isitulo somnikeli owomileyo.
Amathumbu amakhulu anenani elikhulu leentsholongwane. Ezi bhaktheriya zihlala emathunjini akho zibalulekile kwimpilo yakho, kwaye zikhula ngendlela efanelekileyo.
Enye yeebhaktheriya ibizwa Clostridioides ezahlukeneyo (C eyahlukileyo). Kwimali encinci, ayibangeli ngxaki.
- Nangona kunjalo, ukuba umntu ufumana iidosi eziphindaphindayo okanye eziphezulu zentsholongwane kusulelo kwenye indawo emzimbeni, uninzi lweebacteria eziqhelekileyo emathunjini zinokucinywa. Iibhaktheriya zikhula kwaye zikhuphe ityhefu.
- Isiphumo sinokuba sikhulu kakhulu C eyahlukileyo.
- Le tyhefu ibangela ukuba ulwelwesi lwamathumbu amakhulu ludumbe luze lutshise, lubangele umkhuhlane, urhudo kunye nokopha.
Amanye amayeza okubulala iintsholongwane ngamanye amaxesha angazisa C eyahlukileyo iintsholongwane phantsi kolawulo. Ukuba ezi aziphumeleli, i-FMT isetyenziselwa ukubuyisela ezinye C eyahlukileyo ngebacteria "elungileyo" kwaye ubuyisele imali eseleyo.
I-FMT inokusetyenziselwa ukunyanga iimeko ezinje:
- Isifo esibuhlungu sesisu
- Isifo seCrohn
- Ukuqunjelwa
- Ukudumba okwenziwa sisilonda sikabhobhosi
Unyango lweemeko ezingezizo eziphindaphindayo C eyahlukileyo I-colitis ithathwa njengolingo okwangoku kwaye ayisetyenziswanga ngokubanzi okanye yaziwa ngokusebenza.
Umngcipheko we-FMT unokubandakanya oku kulandelayo:
- Impendulo kumayeza owanikiweyo ngexesha lenkqubo
- Ukopha ngamandla okanye okuqhubekayo ngexesha lenkqubo
- Iingxaki zokuphefumla
- Ukusasazeka kwezifo kumxhasi (ukuba umnikeli akakhange ahlolwe kakuhle, nto leyo inqabileyo)
- Usulelo ngexesha lekolonoscopy (kunqabile kakhulu)
- Amahlwili egazi (kunqabile kakhulu)
Umnikeli uya kuthi athathe i-laxative ngobusuku obuphambi kwenkqubo ukuze babe nokuhamba kwamathumbu kusasa olulandelayo. Baza kuqokelela isampulu yendle kwindebe ecocekileyo kwaye beze nayo ngosuku lwenkqubo.
Thetha nomboneleli wakho malunga naziphi na izinto ezaliwa nokwaliwa nawo onke amayeza owathathayo. SUKUYEKE ukuthatha naliphi na iyeza ngaphandle kokuthetha nomboneleli wakho. Kuya kufuneka uyeke ukuthatha nawaphi na amayeza okubulala iintsholongwane kangangeentsuku ezi-2 ukuya kwezi-3 ngaphambi kwenkqubo.
Kuya kufuneka ulandele ukutya okungamanzi. Unokucelwa ukuba uthathe laxatives kubusuku obuphambi kwenkqubo. Kuya kufuneka ulungiselele ikholonoscopy kubusuku obuphambi kwe-FMT. Ugqirha wakho uya kukunika imiyalelo.
Phambi kwenkqubo, uya kunikwa amayeza okwenza ukuba ulale ukuze ungaziva ungonwabanga okanye ube nenkumbulo yovavanyo.
Uya kulala kwicala lakho malunga neeyure ezi-2 emva kwenkqubo enesisombululo kwizibilini zakho. Unokunikwa i-loperamide (Imodium) ukunceda ukucothisa amathumbu akho ukuze isisombululo sihlale sikhona ngeli xesha.
Uya kugoduka kwangolo suku lwenkqubo emva kokuba udlulise umxube wesitulo. Uya kudinga ukukhwela ugoduke, ke qiniseka ukuba uyilungiselela ngaphambi kwexesha. Kuya kufuneka uphephe ukuqhuba, ukusela utywala, okanye nakuphi na ukuphakamisa ubunzima.
Unokuba nomkhuhlane ophantsi ngobusuku emva kwenkqubo. Unokuba nokuqunjelwa, igesi, ukuqumba, kunye nokuqhinwa iintsuku ezimbalwa emva kwenkqubo.
Umboneleli wakho uya kukuyalela malunga nohlobo lokutya kunye namayeza ekufuneka uwathathe emva kwenkqubo.
Olu nyango lusindisa ubomi lukhuselekile kakhulu, lusebenza kwaye, ngexabiso eliphantsi. I-FMT inceda ngokubuyisa izityalo eziqhelekileyo ngesitulo sabanikeli. Oku kunceda ekuvuseleleni imeko yamathumbu kunye nempilo.
Fecal bacteriotherapy; Ukutshintshwa kwesitulo; Ukufakelwa kwe-Fecal; C. difficile colitis - ukufakelwa ilindle; Clostridium difficile - ukufakelwa kwe-fecal; IClostridioides difficile - ukufakelwa kwelindle; I-Pseudomembranous colitis - ukufakelwa kwe-fecal
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