ISenna

Umxholo

• Kusenokwenzeka ukuba iyasebenza ...
• Inokwenzeka ukuba isebenze ...
• Kusenokwenzeka ukuba ayisebenzi ...
• Akukho bungqina baneleyo bokulinganisa ukusebenza ...
• Amanyathelo okhuseleko kunye nezilumkiso:

USenna ngumfuno. Amagqabi kunye nesiqhamo sesityalo zisetyenziselwa ukwenza amayeza.

I-Senna yi-FDA evunyiweyo kwi-counter-the-counter (OTC). Akunyanzelekanga ukuba uthenge i-senna. Isetyenziselwa ukunyanga ukuqhina kunye nokucoca isisu ngaphambi kovavanyo lokuqonda isifo olunjenge colonoscopy.

I-Senna ikwasetyenziselwa isifo samathumbu esinganyanzelekanga (IBS), utyando lwamalungu omqolo okanye i-rectal, iinyembezi kumngxunya we-anus (fissures anal), hemorrhoids, and weight loss.

Isiqhamo seSenna sibonakala silungile kunegqabi leSenna. Oku kukhokelele i-American Herbal Products Association (AHPA) ukuba ilumkise ngokusetyenziswa kwexesha elide kwegqabi le-senna, kodwa hayi iziqhamo ze-senna. I-AHPA icebisa ukuba iimveliso zamagqabi e-senna zibhalwe, "Sukuyisebenzisa le mveliso ukuba unentlungu esiswini okanye isisu esihambisayo. Qhagamshelana nomboneleli wezempilo ngaphambi kokuyisebenzisa ukuba ukhulelwe okanye ungunesi. Yeka ukusetyenziswa xa kunokwenzeka ukuba kukho urhudo okanye ilindle elinamanzi. Do ungagqithi kwidosi ekucetyiswa ukuba yenziwe.

Amayeza endalo aVimba weDatha Ukusebenza kwexabiso ngokusekwe kubungqina besayensi ngokwala manqanaba alandelayo: Ukusebenza, ukusebenza ngokukuko, okunokwenzeka ukuba kusebenze, okungenzeka kungasebenzi, kunokwenzeka ukungasebenzi, ukungasebenzi, kunye nobungqina obungonelanga bokulinganisa.

Ukulinganiswa kokusebenza kwe ISENNA zezi zilandelayo:

Kusenokwenzeka ukuba iyasebenza ...

• Ukuqunjelwa. Ukuthatha i-senna ngomlomo kuyasebenza kunyango lwexeshana lokuqhinwa. ISenna sisiyobisi esamkelweyo yi-FDA sabantu abadala kunye nabantwana abaneminyaka emi-2 nangaphezulu. Nangona kunjalo, kubantwana abaneminyaka emi-3 ukuya kweli-15 ubudala, ioyile yezimbiwa kunye nonyango olubizwa ngokuba yi-lactulose lunokusebenza ngakumbi kunokuthatha i-senna. I-Senna ikwasebenza ngokunyanga ukuqhina xa isetyenziswa ngokudibanisa ne-psyllium okanye i-docusate sodium.Kubantu abadala, i-senna kunye ne-psyllium isebenza ngakumbi kune-lactulose yokunyanga ukuqhina okuqhubekayo. I-Senna kunye ne-docusate sodium iyasebenza ekunyangeni ukuqhina kubantu abadala nakubantu abaye benziwa utyando. Ukuthatha i-senna kubonakala kusebenza njenge-lactulose, i-psyllium, kunye ne-docusate yokuphelisa ukuqunjelwa kubantu abathatha ii-opioids okanye i-loperamide.

Inokwenzeka ukuba isebenze ...

• Ukulungiswa kwamathumbu ngaphambi kwekolonoscopy. Ukuthatha i-senna ngomlomo kuyasebenza njengeoyile ye-castor kunye ne-bisocodyl yokulungiselela amathumbu. Obunye ubungqina bucebisa ukuba i-senna ikwasebenza ubuncinci njenge-polyethylene glycol yokulungiselela amathumbu. Nangona kunjalo, ubungqina obuphikisanayo bukhona. Akucaci ukuba ukuthatha i-senna nge-polyethylene glycol kusebenza ngakumbi kunokuthatha i-polyethylene glycol kuphela. I-Senna ibonakala ingasebenzi kakuhle kune-sodium phosphate yokuhlanjululwa kwamathumbu. Nangona kunjalo, ukuthatha indibaniselwano ye-senna, i-sodium picosulfate, kunye ne-polyethylene glycol kubonakala kusebenza ngakumbi kune-sodium phosphate yokulungiselela amathumbu ngaphambi kwe-colonoscopy. Sebenzisa indibaniselwano yesenna, i-mannitol, i-saline solution, kunye ne-simethicone, ngaphambi kokucinga ngamathumbu ngephilisi ekhethekileyo eginywayo, kubonakala ngathi iyasebenza ngakumbi kunokusebenzisa irejimeni efanayo ngaphandle kwe-senna.

Kusenokwenzeka ukuba ayisebenzi ...

• Ukuqonda isifo. Ukuthatha i-senna ngomlomo akubonakali kuphucula ukubonwa kwamalungu esisu.

Akukho bungqina baneleyo bokulinganisa ukusebenza ...

• Iimpawu.
• Isifo sengqondo sesifo esibuhlungu (IBS).
• Ukunciphisa umzimba.
• Uqhaqho lwe-anus okanye i-rectum.
• Iinyembezi kumngxunya we-anus (fissures anal).
• Ezinye iimeko.

Ubungqina obungakumbi buyafuneka ukukala ukusebenza kwe-senna kwezi zinto zisetyenziswayo.

I-Senna iqulethe iikhemikhali ezininzi ezibizwa ngokuba yi-sennosides. I-Sennosides iyacaphukisa ulwelwesi lwamathumbu, olubangela isiphumo sokuhambisa isisu.

USenna kunjalo NGOKUKHUSELEKILEYO uninzi lwabantu abadala kunye nabantwana abangaphezulu kweminyaka emi-2 xa bethathwa ngomlomo, ixesha elifutshane. I-Senna sisiyobisi esamkelweyo se-FDA. I-Senna inokubangela ezinye iziphumo ebezingalindelekanga kubandakanya ukungahambi kakuhle kwesisu, iicramps, kunye norhudo.

USenna kunjalo OKUNGENZEKA UKHUSELEKILE xa ithathwa ngomlomo ixesha elide okanye ngeedosi eziphezulu. Sukusebenzisa i-senna ngaphezulu kweeveki ezimbini. Ukusetyenziswa ixesha elide kunokubangela ukuba amathumbu ayeke ukusebenza ngesiqhelo kwaye kunokubangela ukuxhomekeka kwizidambisi. Ukusetyenziswa kwexesha elide kunokutshintsha isixa okanye ulungelelwaniso lweekhemikhali ezithile egazini (ii-electrolyte) ezinokubangela ukuphazamiseka kokusebenza kwentliziyo, ubuthathaka bemisipha, ukonakala kwesibindi kunye nezinye iziphumo eziyingozi.

Amanyathelo okhuseleko kunye nezilumkiso:

Ukukhulelwa kunye nokuncancisa: USenna ngu UKHUSELEKO OLUNOKWENZEKA ngexa lokukhulelwa kunye nokuncancisa xa uthathwa ngomlomo, ixesha elifutshane. Yi OKUNGENZEKA UKHUSELEKILE xa ithathwa ngomlomo ixesha elide okanye ngeedosi eziphezulu. Ixesha elide, ukusetyenziswa rhoqo, okanye ukusetyenziswa kweedosi eziphezulu kunxulunyaniswe neziphumo ebezingalindelekanga ezibi kubandakanya ukuxhomekeka kwelaxative kunye nomonakalo wesibindi.

Nangona inani elincinci le-senna liwela kubisi lwebele, akubonakali ngathi yingxaki kwiintsana ezincancisayo. Logama nje umama esebenzisa i-senna kwixabiso elicetyiswayo, i-senna ayibangeli utshintsho kwisantya okanye ukungaguquguquki kwezitulo zeentsana.

Ukuphazamiseka kwe-Electrolyte, ukusilela kwe potassiumUkusetyenziswa gwenxa kwe-senna kunokwenza ezi meko zibe mbi nangakumbi.

Ukuphelelwa ngamanzi emzimbeni, urhudo okanye ilindle elixegayo: I-Senna akufuneki isetyenziswe kubantu abanokuphelelwa ngamanzi emzimbeni, urhudo, okanye izitulo ezivulekileyo. Ingazenza mandundu ezi meko.

Iimeko zesisu (GI): I-Senna akufuneki isetyenziswe ngabantu abaneentlungu esiswini (nokuba bafunyanisiwe okanye abangafumaneki), ukuvaleka kwamathumbu, isifo sikaCrohn, isifo sezilonda, isifo sokuqaqanjelwa sisisu, ukudumba kwesisu, i-anal prolapse, okanye i-hemorrhoids.

Isifo sentliziyo: I-Senna inokubangela ukuphazamiseka kwe-electrolyte kwaye inokwenza ukuba isifo sentliziyo sibe mandundu.

Iphakathi

Lumka ngale nhlanganisela.

Iipilisi zolawulo lokuzalwa (iziyobisi zokuthintela ukukhulelwa)

I-Ethinyl estradiol yindlela ye-estrogen ekwezinye iipilisi zokulawula ukuzalwa. I-Senna inokunciphisa ukuba ingakanani i-estradiol eyifunxa umzimba. Ukuthatha i-senna kunye neepilisi ezithile zolawulo lokuzalwa kunokunciphisa ukusebenza kwazo.

I-Digoxin (Lanoxin)

I-Senna luhlobo lwe-laxative ebizwa ngokuba yi-laxative evuselelayo. I-laxatives ekhuthazayo inokunciphisa amanqanaba e-potassium emzimbeni. Amanqanaba e-potassium asezantsi anokunyusa umngcipheko weziphumo ebezingalindelekanga ze-digoxin (Lanoxin).

Estrogens

Ezinye iipilisi ezisetyenziselwa unyango olubuyisela i-hormone ziqulethe i-estrone yamachiza. I-Senna inokunciphisa inani le-estrone emzimbeni. Ezinye iipilisi ezisetyenziselwa unyango lwehomoni endaweni yazo ziqulathe ikhemikhali i-ethinyl estradiol. I-Senna inokunciphisa ukuba ingakanani i-estradiol eyifunxa umzimba. Ukuthatha i-senna kunokunciphisa iziphumo zonyango lwehomoni.

Ezinye iipilisi ze-estrogen zibandakanya i-equine estrogens (Premarin), i-ethinyl estradiol, i-estradiol kunye nezinye.

IWarfarin (Coumadin)

I-Senna inokusebenza njenge-laxative. Kwabanye abantu, i-senna inokubangela urhudo. Urhudo lunokunyusa iziphumo ze-warfarin kunye nokunyusa umngcipheko wokopha. Ukuba uthatha i-warfarin, sukuyithatha kakhulu i-senna.

Iipilisi zamanzi (iziyobisi zeDiuretic)

USenna sisisu. Ezinye i-laxatives zinokunciphisa i-potassium emzimbeni. "Iipilisi zamanzi" zinokunciphisa i-potassium emzimbeni. Ukuthatha i-senna kunye "neepilisi zamanzi" kunokunciphisa i-potassium emzimbeni kakhulu.

Ezinye "iipilisi zamanzi" ezinokunciphisa i-potassium zibandakanya i-chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), nezinye.

Ukuthengiswa kwehashe

Kukho inkxalabo yokuba ukusebenzisa i-senna kunye ne-horsetail kunokunyusa amathuba okuba amanqanaba e-potassium emzimbeni anokuhla kakhulu.

Licorice

Kukho inkxalabo yokuba ukusebenzisa i-senna kunye ne-licorice kunokunyusa amathuba okuba amanqanaba e-potassium emzimbeni anokuhla kakhulu.

Imifuno yokuvuselela isisu

Kukho inkxalabo yokuba ukusebenzisa i-senna kunye namayeza e-laxative akhuthazayo anokunyusa amathuba okuba amanqanaba e-potassium emzimbeni angahla kakhulu. Imifuno ye-laxative ekhuthazayo ibandakanya i-aloe, i-alder buckthorn, ingcambu emnyama, iflegi eblue, i-butternut bark, i-colocynth, i-buckthorn yaseYurophu, i-fo ti, i-gamboge, i-gossypol, i-bindweed enkulu, i-jalap, imana, ingcambu ye-scammony yaseMexico, i-rhubarb, i-senna kunye ne-yellow dock

Akukho kunxibelelana kwaziwayo nokutya.

La machiza alandelayo afundwe kuphando lwezesayensi:

ABADALA

NGOMLOMO:

• UkuqunjelwaUkuqunjelwa ngokubanzi, idosi eqhelekileyo yi-17.2 mg yonke imihla. Musa ukuthatha ngaphezulu kwe-34.4 mg kabini yonke imihla. Kubantu abadala, i-17 mg mihla le isetyenzisiwe. Ukuqunjelwa emva kokukhulelwa, i-28 mg kwiidosi ezi-2 ezahlukileyo zisetyenzisiwe.
• Ukulungiselela amathumbu: Iidosi ze-senna eziqukethe i-75 mg okanye i-sennosides ithathe usuku ngaphambi kwe-colonoscopy, okanye i-120-150 mg ethathwe kanye okanye kabini ngemini ngaphambi kwe-colonoscopy.

ABANTWANA

NGOMLOMO:

• Kubantwana abaneminyaka eli-12 nangaphezulu, idosi eqhelekileyo ngamacwecwe ama-2, kunye ne-8.6 mg sennosides kwithebhulethi nganye, kube kanye yonke imihla. Elona thamo liphezulu ziipilisi ezi-4 (34.4 mg sennosides) kabini yonke imihla. Kubantwana abaneminyaka emi-6 ukuya kweli-11 iminyaka, idosi eqhelekileyo yipilisi enye (8.6 mg sennosides) yonke imihla. Elona thamo liphezulu ziipilisi ezimbini (17.2 mg sennosides) kabini yonke imihla. Kubantwana abaneminyaka emi-2 ukuya kwemi-5 ubudala, idosi eqhelekileyo yi-1/2 ithebhulethi (4.3 mg sennosides) yonke imihla. Elona thamo liphezulu yithebhulethi enye (8.6 mg sennosides) kabini yonke imihla.

Alexandria Senna, Alexandrinische Senna, Casse, Cassia acutifolia, Cassia angustifolia, Cassia lanceolata, Cassia senna, Fan Xie Ye, Indian Senna, Khartoum Senna, Sen, Sena Alejandrina, Séné, Séné d'Alexandrie, Séné d'Egypte, Ewe, uSéné de Tinnevelly, uSenna alexandrina, uSennae Folium, uSennae Fructus, uSennosides, uTinnevelly Senna, uSenna oyinyani.

Ukuze ufunde okungakumbi malunga nokubhalwa kweli nqaku, nceda ubone Amayeza endalo aVimba weDatha indlela yokusebenza.

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39. I-Kinnunen, O. kunye ne-Salokannel, J. Iziphumo zokuqhubeka nokuziphatha kumathumbu kwizigulana zexesha elide zeemveliso ezenza ubuninzi zexesha elide ezine-laxative evuselelayo. Acta Med Scand. Ngo-1987; 222: 477-479. Jonga i-abstract.
40. UBossi, S., Arsenio, L., Bodria, P., Magnati, G., Trovato, R., noStrata, A. [Ufundo lwezonyango lolungiselelo olutsha olusuka kwimbewu yeplaza kunye neesenna pods]. I-Acta Biomed.Ateneo.Parmense. Ngo-1986; 57 (5-6): 179-186. Jonga i-abstract.
41. IMishalany, H. Amava eminyaka esixhenxe kunye nokuqina kwesisu okungapheliyo. J Isidlangalala. Ngo-1989; 24: 360-362. Jonga i-abstract.
42. ILabenz, J., Hopmann, G., Leverkus, F., kunye neBorsch, G. [Ukucocwa kwamathumbu ngaphambi kwekolonoscopy. Isifundo esinokwenzeka, esingenamkhethe, esingaboniyo nesithelekisayo]. IMed Klin. (EMunich) 10-15-1990; 85: 581-585. Jonga i-abstract.
43. ULazaro, H., Fitzmartin, R. D., kunye noGoldenheim, P. D. Uphando oluninzi lweklinikhi kuvavanyo lwe-morphine ekhutshwe ngomlomo (iipilisi ze-MS Contin) ezinikezelwa kwizigulana ezinomhlaza. Isibhedlele. J 1990; 6: 1-15. Jonga i-abstract.
44. UZiegenhagen, D. J., Zehnter, E., Tacke, W., noKruis, W. Ukongezwa kwe-senna kuphucula ukulungiswa kwe-colonoscopy kunye nokuhlambalaza: ityala elingenangqondo. Isisu. Ngo-1991; 37: 547-549. Jonga i-abstract.
45. USoyuncu, S., Cete, Y., kunye noNokay, A. E. Portal vein thrombosis enxulumene neCassia angustifolia. Kwiklinikhi yetyhefu. (Phila) 2008; 46: 774-777. Jonga i-abstract.
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47. UMcLaughlin, A. F. Anorexia amanosa kunye nokusetyenziswa gwenxa kwe-senna: nephrocalcinosis, iklabhu yedijithali kunye ne-hypertrophic osteoarthropathy. NguMed J Aust. 9-15-2008; 189: 348. Jonga i-abstract.
48. UBailey, S. R., Tyrrell, P. N., kunye noHale, M. Uvavanyo lokuvavanya ukusebenza kakuhle kwamathumbu ngaphambi kokungena ngaphakathi. KwiKlinikhi. Ngo-1991; 44: 335-337. Jonga i-abstract.
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50. Miles, C. L., Fellowes, D., Goodman, M. L., kunye noWilkinson, S. I-Laxatives yolawulo lokuqhinwa kwizigulana zononophelo. Idatha yedatha yeCochrane. Ngo-2006; CD003448. Jonga i-abstract.
51. I-Kositchaiwat, S., Suwanthanmma, W., Suvikapakornkul, R., Tiewthanom, V., Rerkpatanakit, P., kunye neTinkornrusmee, C.Ukuthelekiswa kokufundwa kweerejimeni ezimbini zokulungiselela amathumbu kwi-colonoscopy: iipilisi zesenna vs isisombululo se-sodium phosphate. Kwihlabathi J Gastroenterol. 9-14-2006; 12: 5536-5539. Jonga i-abstract.
52. UPatanwala, A. E., Abarca, J., Huckleberry, Y., kunye no-Erstad, B. L. Ulawulo lwe-Pharmacologic lokuqunjelwa kwisigulana esigula kakhulu. I-Pharmacotherapy 2006; 26: 896-902. Jonga i-abstract.
53. I-Beuers, U., Spengler, U., kunye nePape, G. R. Hepatitis emva kokuxhatshazwa okungapheliyo kwe-senna. ILancet 2-9-1991; 337: 372-373. Jonga i-abstract.
54. Guo, H., Huang, Y., Xi, Z., Ingoma, Y., Guo, Y., kunye no-Na, Y. Ngaba ukulungiswa kwamathumbu ngaphambi kokuba kudityaniswe urology? Ityala elinokwenzeka, elingenamkhethe, elilawulwayo. J Urol. Ngo-2006; 175: 665-668. Jonga i-abstract.
55. URadaelli, F., Meucci, G., Imperiali, G., Spinzi, G., Strocchi, E., Terruzzi, V., kunye no-Minoli, G. I-senna yedosi ephezulu xa kuthelekiswa nokuhlanjwa okuqhelekileyo kwe-PEG-ES njengokulungiselela isisu i-colonoscopy ekhethiweyo: ityala elizayo, elingenamsebenzi, elingaphandiyo. NdinguJ Gastroenterol. 2005; 100: 2674-2680. Jonga i-abstract.
56. Burlefinger, R. J. kunye noSchmitt, W. [Ileta eya kwiJenali yeGastroenterology. Nika izimvo kwinqaku "uSenna okanye i-bisacodyl ngaphambi kokulungiswa kwe-colonoscopy: isifundo esinokuthelekiswa esingenakulinganiswa", nguD. J. Ziegenhagen, uE. Zehnter, W. Tacke, T. H. Gheorghiu, W. Kruis]. Z. IGastroenterol. Ngo-1992; 30: 376. Jonga i-abstract.
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60. UBALDWIN, W. F. UFUNDO LWENKQUBO LOLAWULO LWE-SENNA KOOMAMA ABANGONGAMELAYO: UVAVANYO LWEZIPHUMO KWIMIKHUBA YABASEKHAYA BASABANTWANA. Ngaba, uMed Assoc. J 9-14-1963; 89: 566-568. Jonga i-abstract.
61. UMilner, P., Belai, A., Tomlinson, A., Hoyle, C. H., Sarner, S., kunye noBurnstock, G. Iziphumo zonyango lwexesha elide lokunyanga kwi-neuropeptides kwimikhumbi ye-rat mesenteric kunye ne-caecum. J Pharm, iPharmacol. Ngo-1992; 44: 777-779. Jonga i-abstract.
62. IChilton, AP, O'Sullivan, M., Cox, MA, Loft, DE, kunye noNwokolo, CU Ukuthelekiswa okungaboniyo, okungahleliwe kwinoveli, idosi ephantsi, irejimeni kathathu ngenqanawa ye-phospho-soda: isifundo sokucoceka kwekholon, isantya kunye nempumelelo yekolonoscopy. Endoscopy 2000; 32: 37-41. Jonga i-abstract.
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