Umbhali: Clyde Lopez
Umhla Wokudalwa: 18 Eyekhala 2021
Hlaziya Umhla: 18 Eyenkanga 2024
Anonim
Metabolisme Ca dan P oleh Bu Anindhita Syagata, S.Gz., MPH
Ividiyo: Metabolisme Ca dan P oleh Bu Anindhita Syagata, S.Gz., MPH

Umxholo

Iityuwa zePhosphate zibhekisa kwindibaniselwano ezahlukeneyo zekhemikhali phosphate neetyiwa kunye neeminerali. Ukutya okuphezulu kwi-phosphate kubandakanya iimveliso zobisi, ukutya okuziinkozo okupheleleyo, amandongomane, kunye nenyama ethile. Iifosfathi ezifumaneka kwiimveliso zobisi kunye nenyama kubonakala ngathi zifunxwa ngokulula ngumzimba kunee-phosphates ezifumaneka kwiingqolowa zesiriyeli. Iziselo zeCola ziqulathe i-phosphate eninzi- kakhulu, enyanisweni, inokubangela iphosphate eninzi egazini.

Abantu basebenzisa iityuwa ze-phosphate kunyango. Lumka ungabhidanisi ityuwa ye-phosphate nezinto ezifana ne-organophosphates, eziyityhefu kakhulu.

Iityuwa zephosphate zixhaphake kakhulu ukucoca amathumbu, amanqanaba asezantsi egazi le-phosphate, ukuqhina, amanqanaba aphezulu egazi le-calcium, kunye nokuqaqamba kwentliziyo.

Amayeza endalo aVimba weDatha Ukusebenza kwexabiso ngokusekwe kubungqina besayensi ngokwala manqanaba alandelayo: Ukusebenza, ukusebenza ngokukuko, okunokwenzeka ukuba kusebenze, okungenzeka kungasebenzi, kunokwenzeka ukungasebenzi, ukungasebenzi, kunye nobungqina obungonelanga bokulinganisa.

Ukulinganiswa kokusebenza kwe IZIQULATHO ZEFOSPHATE zezi zilandelayo:


Ukusebenza ...

  • Ukulungisa amathumbu enkqubo yonyango. Ukuthatha iimveliso ze-sodium phosphate ngomlomo ngaphambi kwenkqubo ye-colonoscopy iyasebenza ekucoceni amathumbu. Ezinye iimveliso zesodiyam phosphate (OsmoPrep, Salix Pharmaceuticals; Visicol, Salix Pharmaceuticals) zamkelwe yi-US Food and Drug Administration (FDA) kolu bonakaliso. Nangona kunjalo, ukuthatha i-sodium phosphate kunokunyusa umngcipheko wokonzakala kwezintso kwabanye abantu. Ngesi sizathu, iimveliso zesodium phosphate azisasetyenziswa rhoqo e-US ukulungiselela amathumbu.
  • Amanqanaba aphantsi e-phosphate egazini. Ukuthatha isodiyam okanye i-potassium phosphate ngomlomo kuyasebenza ekuthinteleni okanye ekunyangeni amanqanaba asezantsi e-phosphate egazini. Iityuwa zephosphate efakwa ngaphakathi inokunyanga amanqanaba asezantsi e-phosphate egazini xa isetyenziswa phantsi kweliso likagqirha.

Kusenokwenzeka ukuba iyasebenza ...

  • Ukuqunjelwa. Isodium phosphate sisixhobo esivunyelwe yi-FDA ngaphezulu kwekhawuntari (OTC) yonyango lokuqhinwa. Ezi mveliso zithathwa ngomlomo okanye zisetyenziswe njenge-enemas.
  • Ukutya. I-Aluminium phosphate kunye ne-calcium phosphate zizithako ezivunyelweyo ze-FDA ezisetyenziswa kwii-antacids.
  • Amanqanaba aphezulu e-calcium egazini. Ukuthatha ityuwa ye-phosphate (ngaphandle kwe-calcium phosphate) ngomlomo kunokwenzeka ukuba isebenze ekunyangeni amanqanaba aphezulu e-calcium egazini. Kodwa iityuwa zephosphate efakwa emithanjeni akufuneki zisetyenziswe.

Inokwenzeka ukuba isebenze ...

  • Amatye eentso (nephrolithiasis). Ukuthatha i-potassium phosphate ngomlomo kunokunceda ekuthinteleni amatye e-calcium kwizintso ekubeni zenze kwizigulana ezinamanqanaba aphezulu e-calcium kumchamo.

Akukho bungqina baneleyo bokulinganisa ukusebenza ...

  • Ukusebenza kwezemidlalo. Olunye uphando lwakwangoko lubonisa ukuba ukuthatha i-sodium phosphate ngomlomo kangangeentsuku ezi-6 ngaphambi kokuhamba ngamandla ngebhayisikile okanye isprinta kunokuphucula ukusebenza kwezemidlalo. Kodwa olunye uphando lwangaphambili alubonisi sibonelelo. Izifundo ezingaphezulu ziyafuneka kumaqela amakhulu abantu ukuze babone ukuba isodiyam phosphate iluncedo ngenene. Ukuthatha ezinye iityuwa ze-phosphate ezifana ne-calcium phosphate okanye i-potassium phosphate akuphuculi ukusebenza okanye ukuhamba ngebhayisikile.
  • Isifo seswekile (isifo seswekile ketoacidosis). Uphando lwakwangoko lubonisa ukuba ukunika i-potassium phosphate ngaphakathi ngaphakathi (nge-IV) akuphuculi ingxaki yeswekile apho umzimba uvelisa iiasidi zegazi ezininzi ezibizwa ngokuba zii-ketone. Abantu abanale meko kufuneka banikwe kuphela i-phosphates ukuba banamanqanaba asezantsi e-phosphate.
  • Unyango. Uphando lubonisa ukuba ukuthatha i-calcium phosphate ngomlomo kunceda ukuphucula ukuxinana kwethambo lomqolo kunye nomqolo osezantsi kubafazi abane-osteoporosis. Kodwa ayisebenzi ngcono kuneminye imithombo yecalcium, enjengecalcium carbonate.
  • Iingxaki ezenzekayo xa kutyiwa kubantu ababekade belamba (Refeeding syndrome). Uphando lwakwangoko lubonisa ukuba ukunika isodiyam kunye ne-potassium phosphate ngaphakathi (nge-IV) ngaphezulu kweeyure ezingama-24 kuthintela ukuqaqanjelwa kwesifo xa uqala ngokutsha isondlo kubantu abangondlekanga kakhulu okanye abalambileyo.
  • Amazinyo abuthathaka.
  • Ezinye iimeko.
Ubungqina obungakumbi buyafuneka ukukala iityuwa ze-phosphate kwezi zinto zisetyenziswayo.

Iifosfathi zihlala zithathwa ekutyeni kwaye zibalulekile ziikhemikhali emzimbeni. Bayabandakanyeka kulwakhiwo lweseli, ukuthuthwa kwamandla kunye nokugcinwa, umsebenzi weevithamini, kunye nezinye iinkqubo ezininzi eziyimfuneko empilweni. Iityuwa ze-Phosphate zinokusebenza njenge-laxatives ngokubangela ukuba ulwelo oluninzi lutsalwe emathunjini kwaye lukhuthaze amathumbu ukuba akhuphe umxholo wawo ngokukhawuleza.

Iityuwa zePhosphate eziqukethe isodiyam, potassium, ialuminiyam, okanye icalcium NGOKUKHUSELEKILEYO kubantu abaninzi xa bethathwe ngomlomo, bafakwa kwi-rectum, okanye banikwa ngaphakathi (nge-IV) ngokufanelekileyo nangexesha elifutshane. Iityuwa zephosphate kufuneka zisetyenziswe ngaphakathi ngaphakathi (nge-IV) phantsi kweliso likagqirha.

Iityuwa zePhosphate (ezichazwe njengephosphorus) zezi OKUNGENZEKA UKHUSELEKILE xa kuthathwa ngeedosi ngaphezulu kwe-4 gram ngosuku kubantu abadala abangaphantsi kweminyaka engama-70 ubudala kunye ne-3 gram ngemini kubantu abadala.

Ukusetyenziswa kwexesha elide kunokuphazamisa ibhalansi ye-phosphates kunye nezinye iikhemikhali emzimbeni kwaye kufuneka zijongwe ngumqeqeshi wezempilo ukukhusela imiphumo emibi. Iityuwa zePhosphate zinokucaphukisa umgudu wokugaya ukutya kwaye zibangele isisu, urhudo, ukuqhina, intloko ebuhlungu, ukudinwa kunye nezinye iingxaki.

Musa ukudibanisa iityuwa ze-phosphate kunye nezinto ezinje nge-organophosphates, okanye nge-tribasic sodium phosphates kunye ne-tribasic potassium phosphates, eziyityhefu kakhulu.

Amanyathelo okhuseleko kunye nezilumkiso:

Ukukhulelwa kunye nokuncancisaIityuwa zephosphate ezivela kwimithombo yokutya zezi NGOKUKHUSELEKILEYO Abasetyhini abakhulelweyo okanye abancancisayo xa besebenzisa izibonelelo ezicetyiswayo ze-1250 mg mihla le koomama abaphakathi kweminyaka eyi-14-18 ubudala kunye ne-700 mg mihla le kwabo baneminyaka engaphezulu kwe-18 ubudala. Ezinye izixa zi OKUNGENZEKA UKHUSELEKILE kwaye kufuneka isetyenziswe kuphela ngengcebiso kunye nokunakekelwa okuqhubekayo kwengcali yezempilo.

Abantwana: Iityuwa zephosphate zi NGOKUKHUSELEKILEYO kubantwana xa besetyenziswa kwizibonelelo zemihla ngemihla ezicetyiswayo ezingama-460 mg kubantwana abaneminyaka engama-1-3 ubudala; I-500 mg yabantwana abaneminyaka engama-4-8 ubudala; kunye no-1250 mg wabantwana abaneminyaka eli-9-18 ubudala. Iityuwa zePhosphate OKUNGENZEKA UKHUSELEKILE ukuba isixa se-phosphate esisetyenzisiweyo (esichazwe njenge-phosphorus) singaphezulu kwenqanaba lokutya elinyamezelwayo (ul). Ii-ULs zii-3 gram ngosuku ngabantwana abaneminyaka eyi-1-8; kunye ne-4 gram ngosuku kubantwana abaneminyaka eli-9 nangaphezulu.

Isifo sentliziyoThintela ukusebenzisa iityuwa ze-phosphate eziqulathe isodiyam ukuba unesifo sentliziyo.

Ukugcinwa kwamanzi (i-edema)Thintela ukusebenzisa iityuwa ze-phosphate eziqulathe isodiyam ukuba une-cirrhosis, ukusilela kwentliziyo, okanye ezinye iimeko ezinokubangela i-edema.

Amanqanaba aphezulu e-calcium egazini (hypercalcemia)Sebenzisa iityuwa ze-phosphate ngobunono xa une-hypercalcemia. I-phosphate eninzi kakhulu inokubangela ukuba i-calcium ifakwe apho ingafanelekanga emzimbeni wakho.

Amanqanaba aphezulu e-phosphate egazini: Abantu abanesifo iAddison, isifo sentliziyo kunye nesifo semiphunga, isifo sezintso, iingxaki ze-thyroid, okanye isifo sesibindi kunokwenzeka ngakumbi kunabanye abantu ukuba bahlakulele i-phosphate eninzi egazini labo xa bethatha iityuwa ze-phosphate. Sebenzisa iityuwa ze-phosphate kuphela ngengcebiso kunye nokhathalelo oluqhubekayo lobungcali kwezempilo ukuba unayo enye yezi meko.

Isifo sezintso: Sebenzisa iityuwa ze-phosphate kuphela ngengcebiso kunye nokhathalelo oluqhubekayo lobungcali kwezempilo ukuba uneengxaki zezintso.

Iphakathi
Lumka ngale nhlanganisela.
IBisphosphonates
Amayeza e-Bisphosphonate kunye neetyuwa ze-phosphate zinokunciphisa amanqanaba e-calcium emzimbeni. Ukuthatha isixa esikhulu seetyuwa ze-phosphate kunye namayeza e-bisphosphonate kunokubangela amanqanaba e-calcium ukuba abe sezantsi kakhulu.

Ezinye ii-bisphosphonates zibandakanya ialendronate (Fosamax), etidronate (Didronel), risedronate (Actonel), tiludronate (Skelid), kunye nabanye.
Ikhalsiyam
Iphosphate inokudibana necalcium. Oku kunciphisa amandla omzimba okufumana i-phosphate kunye ne-calcium. Ukuthintela ukuhlangana, iphosphate kufuneka ithathwe ubuncinci iiyure ezi-2 ngaphambi okanye emva kokuthatha ikhalsiyam.
Intsimbi
Iphosphate inokudibana nentsimbi. Oku kunciphisa amandla omzimba okufumana i-phosphate kunye nentsimbi. Ukuthintela oku kunxibelelana, iphosphate kufuneka ithathwe ubuncinci iiyure ezi-2 ngaphambi okanye emva kokuthatha i-iron.
Magnesium
Iphosphate inokudibana nemagniziyam. Oku kunciphisa amandla omzimba okufumana i-phosphate kunye ne-magnesium. Ukuthintela ukuhlangana, i-phosphate kufuneka ithathwe ubuncinci iiyure ezi-2 ngaphambi okanye emva kokuthatha i-magnesium.
Ukutya okune-phosphate kunye neziselo
Kwithiyori, ukuthatha i-phosphate kunye nokutya okune-phosphate kunye neziselo kunokunyusa amanqanaba e-phosphate kunye nokunyusa umngcipheko weziphumo ebezingalindelekanga, ngakumbi kubantu abaneengxaki zezintso. Ukutya okune-phosphate kunye neziselo kubandakanya i-cola, iwayini, ibhiya, ukutya okuziinkozo okupheleleyo, amandongomane, iimveliso zobisi kunye nenyama.
La machiza alandelayo afundwe kuphando lwezesayensi:

NGOMLOMO:
  • Ukuphakamisa amanqanaba e-phosphate aphantsi kakhulu: Ababoneleli ngezempilo balinganisa amanqanaba e-phosphate kunye ne-calcium egazini kwaye banike i-phosphate eyaneleyo ukulungisa ingxaki.
  • Ukunciphisa amanqanaba e-calcium aphezulu kakhulu: Ababoneleli ngezempilo balinganisa amanqanaba e-phosphate kunye ne-calcium egazini kwaye banike i-phosphate eyaneleyo ukulungisa ingxaki.
  • Ukulungiselela amathumbu enkqubo yonyangoIipilisi ezintathu ukuya kwezine (OsmoPrep, Salix Pharmaceuticals; Visicol, Salix Pharmaceuticals) nganye iqulethe i-1.5 gram yesodium phosphate ithathwa ngee-ounces eziyi-8 zamanzi qho ngemizuzu eli-15 iyonke ngamacwecwe angama-20 ngokuhlwa ngaphambi kwe-colonoscopy. Ngentsasa elandelayo, amacwecwe ama-3-4 athathwa ngee-ounces eziyi-8 zamanzi rhoqo kwimizuzu eli-15 de kwathathwa iipilisi ezili-12-20.
  • Amatye eentso (nephrolithiasis): I-Potassium kunye ne-sodium phosphate salts ebonelela nge-1200-1500 mg ye-elemental phosphate yemihla ngemihla isetyenzisiwe.
NGU-IV:
  • Ukuphakamisa amanqanaba e-phosphate aphantsi kakhuluKusetyenziswe iimveliso ze-Intravenous (IV) eziqukethe i-sodium phosphate okanye i-potassium phosphate. Imithamo ye-15-30 mmol inikwe ngaphezulu kweeyure ezi-2 ukuya kwezi-12. Kusetyenziswe amanani aphakamileyo xa kufuneka njalo.
Izibonelelo zokutya zemihla ngemihla ezicetyiswayo (RDAs) ze-phosphate (ezichazwe njenge-phosphorus) zezi: Abantwana abaneminyaka engama-1-3, 460 mg; abantwana iminyaka 4-8, 500 mg; Amadoda nabasetyhini iminyaka eli-9-18, 1250 mg; Amadoda nabasetyhini ngaphezulu kweminyaka eli-18, 700 mg.
Inani eloneleyo (AI) leentsana zezi: 100 mg yeentsana ezinenyanga ezi-0-6 ubudala kunye nama-275 mg kwiintsana ezisi-7-12 zeenyanga ubudala.
Amanqanaba okuTya okuphezulu okunganyamezelekiyo (i-UL), elona nqanaba liphezulu lokuthathwa apho kungalindelwanga ziphumo ebezingalindelekanga, ze-phosphate (echazwe njenge-phosphorus) ngosuku yile: abantwana abaneminyaka eyi-1-8, i-3 gram ngosuku; abantwana kunye nabantu abadala iminyaka 9-70, 4 grams; abadala ngaphezu kweminyaka engama-70, 3 grams; abasetyhini abakhulelweyo iminyaka eli-14-50, 3.5 grams; kunye nabasetyhini abancancisayo iminyaka eyi-14-50, 4 iigrem. Aluminium phosphate, Bone Phosphate, Calcium phosphate, Calcium Orthophosphate, Calcium Phosphate Dibasic Anhydrous, Calcium Phosphate-Bone Ash, Calcium Phosphate Dibasic Dihydrate, Calcium Phosphate Dibasique Anhydre, Calcium Phosphate Dibasique Dihydrate, Calcium Phosphate Dibasas, , Di-Calcium Phosphate, Dicalcium Phosphate, Dicalcium Phosphate, Neutral Calcium Phosphate, Orthophosphate de Calcium, Phosphate d'Aluminium, Phosphate de Calcium, Phosphate de Magnésium, Phosphate Neutre de Calcium, Phosphate d'Os, Phosphate Tricalcium, Precipitated Calcium Phosphate, Précipitation du Phosphate de calcium, Précipité de Phosphate de Calcium, Tertiary Calcium Phosphate, Tricalcium Phosphate, Whitlockite, Magnesium Phosphate, Merisier, Potassium phosphate, Dibasic Potassium Phosphate, iDipotassium Hydrogen Orthophosphate, iDipotassium Monophosphate, i-Phosphate yePhosphate , Potassium Biphosphate, Potassium Dihydrogen Orthophosphate, Potassium Hydrogen Phosphate, Phosphate de Dipotassium, Phosphate d'Hydrogène de Potassium, Phosphate de Potassium, Phosphate de Potassium Dibasique, Phosphate de Potassium Monobasique, Sodium phosphate, Anhydrous Sodium Phosphate, Dibasifosifidi , Disodium Hydrogen Orthophosphate Dodecahydrate, Disodium Hydrogen Phosphate, Disodium Phosphate, Phosphate of Soda, Sales de Fosfato, Sels de Phosphate, Sodium Orthophosphate, Orthophosphate Disodique d'Hydrogène, Phosphate Disodique d'Hydrogène, Orthophosphate de Sodium, Phosphate deodium, Phosphate deodium de Sodium Dibasique, Phosphorus.

Ukuze ufunde okungakumbi malunga nokubhalwa kweli nqaku, nceda ubone Amayeza endalo aVimba weDatha indlela yokusebenza.


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