Umbhali: Virginia Floyd
Umhla Wokudalwa: 7 Eyethupha 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
Structure, SAR & MOA of Oxazolidinediones (Antiepileptic, Anticonvulsants, Medi Chem-I, Trimethadion
Ividiyo: Structure, SAR & MOA of Oxazolidinediones (Antiepileptic, Anticonvulsants, Medi Chem-I, Trimethadion

Umxholo

I-Trimethadione isetyenziselwa ukulawula ukuthintela ukungabikho (petit mal; uhlobo lokuthimba apho kukho ilahleko emfutshane kakhulu yokwazisa ngexesha umntu anokujonga ngqo phambili okanye aqhwanyaze kwaye angaphenduli kwabanye) xa amanye amayeza engasebenzi . I-Trimethadione ikwiklasi yamayeza abizwa ngokuba zii-anticonvulsants. Isebenza ngokunciphisa izinto ezingaqhelekanga zombane kwingqondo.

I-Trimethadione iza njengethebhulethi ehlafunwayo ukuyithatha ngomlomo. Ihlala ithathwa kathathu okanye kane ngemini. Thatha i-trimethadione kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-trimethadione ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Amacwecwe ahlafunwayo anokuhlafunwa okanye aginywe aphelele.

I-Trimethadione inokunceda ukulawula imeko yakho kodwa ayizukuyinyanga. Qhubeka uthathe i-trimethadione nokuba uziva uphilile. Sukuyeka ukuthatha i-trimethadione ungakhange uthethe nogqirha wakho. Ugqirha wakho mhlawumbi uya kunciphisa umthamo wakho ngokuthe ngcembe. Ukuba ngequbuliso uyeka ukuthatha i-trimethadione, ukubanjwa kwakho kunokuba mandundu.


Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-trimethadione kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seyeza.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-trimethadione,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-trimethadione, nawaphi na amanye amayeza, okanye naziphi na izithako zepilisi ze-trimethadione. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza okubanda okanye i-aleji; amayeza okudakumba; amayeza eentlungu; amanye amayeza okuxhuzula; ukuthomalalisa; iipilisi zokulala; okanye izinto ezizolisayo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ubukhe unayo, oke waba negazi, unxinzelelo, iingxaki zemood, ukuzibulala (ukucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo) iingcinga okanye isimilo, okanye iliso, izintso, okanye isifo sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Abasetyhini abanokukhulelwa ngokubanzi akufuneki bathathe i-trimethadione. Nangona kunjalo, wena kunye nogqirha wakho unokuthatha isigqibo sokuba i-trimethadione iyadingeka ukunyanga imeko yakho. Kwimeko apho kuya kufuneka uthethe nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwa ngelixa usebenzisa eli yeza, biza ugqirha wakho. I-Trimethadione inokulimaza umbungu.
  • ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-trimethadione.
  • Kuya kufuneka uyazi ukuba eli chiza linokukwenza ukuba ube nesiyezi okanye uyozele. Sukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela ekuchaphazela ngayo oku.
  • thintela ukusebenzisa iziselo ezinxilisayo ngelixa uthatha i-trimethadione. Utywala bunokwenza iziphumo ebezingalindelekanga ukuba zibi ngakumbi.
  • Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga kwaye ungazibulala ngelixa uthatha i-trimethadione. Inani elincinci labantu abadala kunye nabantwana abaneminyaka emi-5 ubudala nangaphezulu (malunga ne-1 kubantu abangama-500) abathathe ii-anticonvulsants ezinje nge-trimethadione ukunyanga iimeko ezahlukeneyo ngexesha lezifundo zeklinikhi bazibulala ngexesha lonyango lwabo. Abanye baba bantu bakhulise iingcinga zokuzibulala kunye nokuziphatha kwiveki nje enye emva kokuba beqalisile ukuthatha amayeza. Kukho umngcipheko wokuba unokufumana utshintsho kwimpilo yakho yengqondo ukuba uthatha amayeza e-anticonvulsant anje nge-trimethadione, kodwa kusenokubakho umngcipheko wokuba uya kufumana utshintsho kwimpilo yakho yengqondo ukuba imeko yakho ayinyangwa. Wena kunye nogqirha wakho niya kuthatha isigqibo sokuba ngaba ingozi yokuthatha iyeza le-anticonvulsant inkulu kuneengozi zokungawasebenzisi amayeza. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: uloyiko; ukuphazamiseka okanye ukungazinzi; okutsha okanye ukuhla kokucaphuka, uxinzelelo, okanye uxinzelelo; ukwenza izinto eziyingozi; ubunzima bokuwa okanye ukulala; ndlongondlongo, umsindo okanye ubundlobongela; i-mania (i-frenzied, i-mood engaqhelekanga) ukuthetha okanye ukucinga ngokufuna ukuzenzakalisa okanye ukuzibulala; Ukurhoxa kubahlobo nakusapho; ukuxakeka kukufa nokufa; ukuphisa ngezinto ezixabisekileyo; okanye naluphi na olunye utshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ukhumbula idosi ephosiweyo ngexesha olicwangciselwe ukuthatha idosi elandelayo, tsiba idosi ephosiweyo ngokupheleleyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Trimethadione inokubangela iziphumo ebezingalindelekanga. Xelela ugqirha wakho ukuba ngaba kukho enye yezi mpawu okanye ezo zidweliswe kwiCandelo LOKUGCINWA OKUKHETHEKILEYO zinzima okanye azihambi:

  • ukudinwa
  • utshintsho kubunzima
  • hiccups
  • intloko ebuhlungu
  • ukuba ndindisholo, ukutshisa, okanye ukurhawuzelela izandla, iingalo, iinyawo okanye imilenze
  • ubunzima bokulala okanye ukulala
  • ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

  • ubunzima bokulungelelanisa iintshukumo
  • uvakalelo elangeni
  • intlungu edibeneyo okanye yemisipha
  • iintlungu esifubeni okanye ukuphefumla kancinci
  • ukudumba kweenyawo zakho, amaqatha okanye imilenze
  • ubuthathaka beengalo okanye imilenze yakho
  • kunzima ukugwinya
  • iingxaki zokuthetha
  • irhashalala ezidleleni okanye kwamanye amalungu omzimba
  • urhwebo
  • izilonda emlonyeni
  • ukutyunyuzwa ngokulula
  • amabala abomvu obomvu okanye omfusa
  • impumlo enegazi
  • iintsini ezophayo
  • ukopha okungaqhelekanga
  • ubuthathaka obukhulu okanye ukudinwa
  • mthubi ulusu okanye amehlo
  • umchamo omnyama
  • isicaphucaphu okanye ukugabha
  • Ukuphelelwa ngumdla wokutya
  • iintlungu kwinxalenye ephezulu yesisu
  • ifiva
  • amadlala adumbileyo
  • umqala obuhkungu
  • ukuncipha kokuchama
  • iinkophe droopy
  • ukungaboni kakuhle
  • iingxaki zokubona ekukhanyeni okuqaqambileyo
  • ukuxhuzula

I-Trimethadione inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina trimethadione iipilisi ezihlafunwayo kwifriji.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • ukozela
  • isicaphucaphu
  • isiyezi
  • ubunzima bokulungelelanisa iintshukumo
  • utshintsho kumbono
  • isiqaqa (ukulahleka kwengqondo ixesha elithile)

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-trimethadione.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Tridione®
Ukuhlaziywa kokugqibela-06/15/2018

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