Duloxetine

Umxholo

• Ngaphambi kokuba uthathe i-duloxetine,
• I-Duloxetine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, okanye ezo zikhankanyiweyo KWISILUMKISO ESIBALULEKILEYO okanye KULUNGILE, biza ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inani elincinci labantwana, ulutsha, kunye nabantu abadala abancinci (ukuya kuthi ga kwi-24 yeminyaka ubudala) abathathe i-anti-depressants ('' elevators elevator '') ezifana ne-duloxetine ngexesha lezifundo zeklinikhi baba ukuzibulala (ukucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama yenza njalo). Abantwana, ulutsha, kunye nabantu abadala abancinci abathatha i-anti-depressant ukunyanga uxinzelelo okanye ezinye izifo zengqondo banokuba semngciphekweni wokuzibulala kunabantwana, ulutsha, kunye nabantu abadala abancinci abangazithathiyo ukunyanga ezi meko. Nangona kunjalo, iingcali aziqinisekanga malunga nokuba ungakanani na lo mngcipheko kwaye ingakanani ekufuneka ithathelwe ingqalelo xa usenza isigqibo sokuba ingaba umntwana okanye ulutsha kufuneka athathe i-anti-depressant. Abantwana abangaphantsi kweminyaka eli-18 ubudala akufuneki bathathe i-duloxetine, kodwa kwezinye iimeko, ugqirha unokuthatha isigqibo sokuba i-duloxetine lelona nyango lilungileyo lokunyanga imeko yomntwana.

Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga xa uthatha i-duloxetine okanye ezinye i-anti-depressants nokuba umdala ngaphezulu kweminyaka eyi-24. Olu tshintsho lunokwenzeka nokuba awunasifo sengqondo kwaye uthatha i-duloxetine ukunyanga uhlobo olwahlukileyo lwemeko. Ungazibulala, ngakumbi ekuqaleni konyango lwakho nangalo naliphi na ixesha apho idosi yakho inyuswe okanye yehlisiwe. Wena, usapho lwakho, okanye umnonopheli kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: ukudakumba okutsha okanye okuya kusiba mandundu; ukucinga ngokuzenzakalisa okanye ukuzibulala, okanye ukucwangcisa okanye ukuzama ukwenza njalo; ukukhathazeka kakhulu; ukuphazamiseka; uloyiko; ubunzima bokulala okanye ukulala; indlela yokuziphatha enengcwangu okanye enobutshaba; ukucaphuka; ukwenza ngaphandle kokucinga; ukungazinzi okukhulu; ukonwaba okungaqhelekanga; okanye naluphi na olunye utshintsho olungaqhelekanga kwindlela yokuziphatha. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyakujonga yonke imihla kwaye uyazi ukuba zeziphi iimpawu ezinokubanzima ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango wedwa.

Umboneleli wakho wezempilo uya kufuna ukukubona rhoqo ngelixa uthatha i-duloxetine, ngakumbi ekuqaleni konyango lwakho. Qiniseka ukuba ugcina lonke ixesha lokundwendwela eofisini nogqirha wakho.

Ugqirha okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-duloxetine. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Unokufumana nesikhokelo samayeza kwiwebhusayithi ye-FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

Kungakhathaliseki ubudala bakho, ngaphambi kokuba uthathe i-anti-depressant, wena, umzali wakho, okanye umnakekeli wakho kufuneka uthethe nodokotela wakho malunga neengozi kunye neenzuzo zokunyanga imeko yakho nge-anti-depressant okanye ngezinye iindlela zonyango. Kuya kufuneka uthethe ngomngcipheko kunye nezibonelelo zokungayinyangi imeko yakho. Kuya kufuneka uyazi ukuba ukudakumba okanye esinye isifo sengqondo sonyusa kakhulu umngcipheko wokuba ungazibulala. Lo mngcipheko uphezulu ukuba wena okanye nabani na kusapho lwakho ukhe waba nengxaki yokuphazamiseka engqondweni (imood etshintsha ukusuka ekudandathekeni iye ekubeni nemincili engaqhelekanga) okanye i-mania (ididekile, idlamke ngokungaqhelekanga), uxinzelelo, okanye ucinge okanye uzame ukuzibulala. Thetha nogqirha wakho malunga nemeko yakho, iimpawu, kunye nembali yonyango lwakho kunye nosapho. Wena kunye nogqirha wakho uya kuthatha isigqibo sokuba loluphi uhlobo lonyango olulungele wena.

I-Duloxetine isetyenziselwa ukunyanga uxinzelelo kubantu abadala kunye noxinzelelo ngokubanzi (GAD; uxinzelelo olugqithisileyo kunye noxinzelelo oluphazamisa ubomi bemihla ngemihla kwaye luhlala iinyanga ezi-6 okanye ngaphezulu) kubantu abadala nakubantwana abaneminyaka esi-7 nangaphezulu. I-Duloxetine ikwasetyenziselwa ukunyanga iintlungu kunye nokutswina okubangelwa sisifo seswekile (ukonakala kwimithambo-luvo enokuthi ikhule kubantu abanesifo seswekile) kubantu abadala kunye ne-fibromyalgia (imeko ehlala ixesha elide enokubangela iintlungu, ukuqina kwemisipha kunye nokuthantamisa, ukudinwa, kunye nobunzima ukulala okanye ukulala) kubantu abadala nakubantwana abaneminyaka eli-13 ubudala nangaphezulu. Isetyenziselwa ukunyanga amathambo okanye iintlungu eziqhubekayo ezinje ngeentlungu ezisezantsi okanye i-osteoarthritis (iintlungu ezidibeneyo okanye ukuqina okunokuba mandundu ngokuhamba kwexesha) kubantu abadala. I-Duloxetine ikudidi lwamayeza abizwa ngokuba yi-serotonin ekhethiweyo kunye ne-norepinephrine reuptake inhibitors (SNRIs). Isebenza ngokwandisa inani le-serotonin kunye ne-norepinephrine, izinto zendalo kwingqondo ezinceda ukugcina ukulinganisela kwengqondo kunye nokuyeka ukuhamba kweempawu zentlungu kwingqondo.

I-Duloxetine iza njengokulibaziseka-kokukhutshwa (kukhupha iyeza emathunjini ukunqanda ukophulwa kwamayeza sisisu acid) iphilisi oza kuyithatha ngomlomo. Xa i-duloxetine isetyenziselwa ukunyanga uxinzelelo, ihlala ithathwa kube kanye okanye kabini ngemini kunye okanye ngaphandle kokutya. Xa i-duloxetine isetyenziselwa ukunyanga uxinzelelo ngokubanzi, iintlungu zesifo seswekile, i-fibromyalgia, okanye iintlungu eziqhubekayo zethambo okanye izihlunu, zihlala zithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-duloxetine malunga namaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-duloxetine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo, thatha rhoqo, okanye uthathe ixesha elide kunokuba umiselwe ngugqirha wakho.

Ginya zonke iicapsule zokukhululwa kulibazisekile; ungahluleli, ungahlaleli, okanye uzityumze. Sukuvula ii-capsule zokukhululwa ezilibazisekileyo kwaye udibanise imixholo kunye nolwelo okanye ufefe imixholo ekutyeni.

Ugqirha wakho unokukuqala kwidosi ephantsi yamayeza kwaye wandise idosi yakho emva kweveki enye.

I-Duloxetine inokunceda ukulawula iimpawu zakho kodwa ayizukuyinyanga imeko yakho. Ingathatha i-1 ukuya kwiiveki ezi-4 okanye ngaphezulu ngaphambi kokuba uve isibonelelo esipheleleyo seduloxetine. Qhubeka nokuthatha i-duloxetine nokuba uziva uphilile. Sukuyeka ukuthatha i-duloxetine ngaphandle kokuthetha nogqirha wakho. Ugqirha wakho uya kunciphisa umthamo wakho ngokuthe ngcembe. Ukuba uyeka ngequbuliso ukuthatha i-duloxetine, unokufumana iimpawu zokurhoxa ezinjenge-nausea; ukugabha; urhudo; ixhala; isiyezi; ukudinwa; intloko ebuhlungu; iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni; ukucaphuka; ubunzima bokulala okanye ukulala; ukubila; namaphupha amabi. Xelela ugqirha wakho ukuba unazo naziphi na kwezi mpawu xa idosixetine yakho yehlile.

I-Duloxetine ngamanye amaxesha isetyenziselwa ukunyanga uxinzelelo lomchamo wokuchama (ukuvuza komchamo ngexesha lomzimba njengokukhohlela, ukuthimla, ukuhleka nokuzilolonga) kubafazi. Thetha nogqirha wakho malunga nokusebenzisa eli yeza ukunyanga imeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-duloxetine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-duloxetine, nawaphi na amanye amayeza, okanye nasiphi na isithako esenziwe kwiipilisi ze-duloxetine ezilibazisekileyo. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-thioridazine okanye i-monoamine oxidase (MAO) inhibitor, efana ne-isocarboxazid (Marplan), linezolid (Zyvox); imethylene eluhlaza okwesibhakabhaka; phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate), okanye ukuba uyekile ukuthatha i-MAO inhibitor kwiintsuku ezili-14 ezidlulileyo. Ugqirha wakho uya kukuxelela ukuba ungathathi i-duloxetine. Ukuba uyeka ukuthatha i-duloxetine, kuya kufuneka ulinde ubuncinci iintsuku ezi-5 ngaphambi kokuba uqale ukuthatha i-MAO inhibitor.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye unyango kunye neevithamini ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); i-antidepressants efana ne-amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), kunye nepritriprine Utywala); antihistamines; i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezifana ne-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); buspirone; cimetidine (iTagamet); umchamo ('iipilisi zamanzi'); fentanyl (Abstral, Actiq, Fentora, Onsolis, nabanye); amayeza okubetha kwentliziyo ngokungaqhelekanga njenge-amiodarone (Cordarone), i-flecainide (Tambocor), i-moricizine (i-Ethmozine), i-propafenone (i-Rythmol), kunye ne-quinidine (i-Quinidex); amayeza oxinzelelo, uxinzelelo oluphezulu lwegazi, ukugula ngengqondo, iintlungu, kunye nesicaphucaphu; ipropranolol (Inderal); amayeza e-migraine iintloko ezinje nge-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), kunye zolmitriptan (Zomig); lithium (Eskalith, Lithobid); Iiproton pump inhibitors ezifana ne-lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), kunye ne-rabeprazole (Aciphex); i-quinolone antibiotics efana ne-ciprofloxacin (Cipro) kunye ne-enoxacin (Penetrex); ukuthomalalisa; ezithile ezikhethiweyo ze-serotonin reuptake inhibitors (ii-SSRIs) ezinjenge-fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox) kunye ne-paroxetine (Paxil); sibutramine (iMeridia); iipilisi zokulala; Inophylline (Theochron, Theolair); itramadol (Ultram); kunye noxinzelelo. Uninzi lwamanye amayeza anokusebenzisana ne-duloxetine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi izongezo zesondlo kunye neemveliso zamayeza owathathayo, ngakumbi iimveliso eziqulathe iSt John's wort okanye i-tryptophan.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala, Xelela ugqirha wakho ukuba ukhe wahlaselwa yintliziyo; igazi elonyukayo; ukuxhuzula; isifo semithambo yegazi (ukuvaleka okanye ukunciphisa imithambo yegazi ekhokelela entliziyweni); okanye intliziyo, isibindi, okanye isifo sezintso. Ukuba unesifo seswekile, qiniseka ukuba uthethe nogqirha wakho malunga nokuba imeko yakho imbi kangakanani ukuze ugqirha wakho athathe isigqibo sokuba ngaba i-duloxetine ikulungele na.
• xelela ugqirha wakho ukuba ukhulelwe, ngakumbi ukuba ukwinyanga ezimbalwa zokugqibela zokukhulelwa kwakho, okanye ukuba ucwangcisa ukukhulelwa okanye ukuncancisa. Ukuba ukhulelwa ngelixa uthatha i-duloxetine, tsalela ugqirha wakho. I-Duloxetine inokubangela iingxaki kwiintsana ezisandul 'ukuzalwa emva kokubeleka ukuba ithathwa kwiinyanga zokugqibela zokukhulelwa.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-duloxetine.
• Kuya kufuneka uyazi ukuba i-duloxetine inokukwenza wozele, ube nesiyezi, okanye ichaphazele ukugweba kwakho, ukucinga okanye ukulungelelanisa. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kweziselo ezinxilisayo ngelixa uthatha i-duloxetine. Utywala bunokunyusa umngcipheko weziphumo ebezingalindelekanga ezibi ezivela kwi-duloxetine.
• Kuya kufuneka uyazi ukuba i-duloxetine inokubangela ukuba ube nesiyezi, ukuba nentloko elula, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo oxokileyo kuyo. Oku kuqheleke ngakumbi xa uqala ukuthatha i-duloxetine okanye ukwanda kwethamo. Ukuthintela le ngxaki, phuma kancinci ebhedini, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.
• Kuya kufuneka uyazi ukuba i-duloxetine inokubangela uxinzelelo lwegazi oluphezulu. Kuya kufuneka ujongiwe uxinzelelo lwegazi ngaphambi kokuqala unyango kwaye rhoqo ngelixa usela la mayeza.
• Kuya kufuneka uyazi ukuba i-duloxetine inokubangela ukuba i-angle-closure glaucoma (imeko apho ulwelo luvaliwe ngequbuliso kwaye lungakwazi ukuphuma esweni kubangele ukonyuka okukhawulezileyo, okuqatha koxinzelelo lwamehlo olunokubangela ukulahleka kombono). Thetha nogqirha wakho malunga nokuhlolwa kwamehlo ngaphambi kokuba uqale ukuthatha eli yeza. Ukuba unesicaphucaphu, iintlungu zamehlo, utshintsho kumbono, njengokubona amakhonkco anemibala ajikeleze izibane, kunye nokudumba okanye ukuba bomvu ngaphakathi okanye ejikeleze iliso, tsalela ugqirha okanye ufumane unyango olukhawulezileyo kwangoko.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Duloxetine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• isilungulela
• isisu esibuhlungu
• ukunciphisa ukutya
• umlomo owomileyo
• ukwanda komchamo
• ubunzima bokuchama
• ukubila okanye ukubila ebusuku
• isiyezi
• intloko ebuhlungu
• ukudinwa
• ubuthathaka
• ukozela
• iintlungu zezihlunu okanye iicramps
• utshintsho kwiminqweno yesini okanye amandla
• ukushukuma okungalawulekiyo kwilungu lomzimba

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, okanye ezo zikhankanyiweyo KWISILUMKISO ESIBALULEKILEYO okanye KULUNGILE, biza ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• ukugruzuka okanye ukopha okungaqhelekanga
• iintlungu kwinxalenye ephezulu yesisu
• ukudumba kwesisu
• ukurhawuzelela
• mthubi ulusu okanye amehlo
• umchamo omnyama ngombala
• Ukuphelelwa ngumdla wokutya
• ukudinwa kakhulu okanye ubuthathaka
• ukudideka
• Iimpawu ezinjengomkhuhlane
• umkhuhlane, ukubila, ukudideka, ukubetha kwentliziyo okukhawulezayo okanye okungaqhelekanga, kunye nokuqina kwemisipha
• ifiva
• i-blisters okanye i-peeling skin
• irhashalala
• urhwebo
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa

I-Duloxetine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukuphazamiseka
• i-hallucinating (ukubona izinto okanye ukuva amazwi angabikho)
• ukubetha kwentliziyo ngokukhawuleza
• ifiva
• ukulahleka koququzelelo
• isicaphucaphu
• ukugabha
• urhudo
• ukozela
• ukuxhuzula
• isiyezi
• intloko elula
• isiqaqa
• ukungaphenduli

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICymbalta^®