I-Temsirolimus

Umxholo

• Ngaphambi kokuba uthathe i-temsirolimus,
• I-Temsirolimus inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Temsirolimus isetyenziselwa ukunyanga i-renal cell carcinoma (RCC, uhlobo lomhlaza oqala kwizintso). I-Temsirolimus ikudidi lwamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga exelela iiseli zomhlaza ukuba zande. Oku kunokunceda ukunciphisa ukukhula kwamathumba.

I-Temsirolimus iza njengesisombululo (ulwelo) ukuba sinikezwe ngokufakwa (inaliti encinci kwi-vein) ngaphezulu kwemizuzu engama-30 ukuya kuma-60. Ihlala inikwa ngugqirha okanye ngumongikazi kwiofisi kagqirha okanye kwiziko lokumnika. I-Temsirolimus idla ngokunikwa kanye ngeveki.

Unokufumana iimpawu ezinje ngemingxunya, irhashalala, ukurhawuzelela, ubunzima bokuphefumla okanye ukugwinya, ukudumba kobuso, ukugungxula, okanye iintlungu zesifuba. Tshela ugqirha wakho okanye omnye umboneleli wezempilo ukuba ufumana ezi mpawu ngelixa ufumana i-temsirolimus. Ugqirha wakho unokuyalela amanye amayeza ukunceda ukuthintela okanye ukunciphisa ezi mpawu. Ugqirha wakho uya kukunika la mayeza ngaphambi kokuba ufumane idosi nganye ye-temsirolimus.

Ngaphambi kokuba uthathe i-temsirolimus,

• xelela ugqirha wakho ukuba ngaba uxabana ne-temsirolimus, sirolimus, antihistamines, nawaphi na amanye amayeza, i-polysorbate 80, okanye nasiphi na isithako kwisisombululo se-temsirolimus. Buza ugqirha wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin); amayeza athile okubulala anje nge-itraconazole (Sporanox); ketoconazole (Nizoral); kunye nevoriconazole (Vfen); i-clarithromycin (i-Biaxin); dexamethasone (Decadron); amayeza athile asetyenziselwa ukunyanga i-HIV / AIDS njenge-atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), kunye ne-saquinavir (Invirase); amayeza athile okubanjwa njenge-carbamazepine (i-Equetro, iTegretol), i-phenobarbital (i-Luminal), kunye ne-phenytoin (i-Dilantin, i-Phenytek); amayeza ukunciphisa cholesterol kunye lipids; nefazodone; irifabutin (Mycobutin); irifampin (Rifadin, Rifamate, Rifiter); ii-inhibitors ezikhethiweyo ze-serotonin ezinje nge-citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), kunye sertraline (Zoloft); i-sirolimus (iRapamune, iRapamycin); i-sunitinib (uSutent); kunye ne-telithromycin (Ketek). Uninzi lwamanye amayeza anokusebenzisana ne-temsirolimus, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Qiniseka ukuba uxelela ugqirha kunye nosokhemesti ukuba uyeka ukuthatha elinye lala machiza adweliswe apha ngasentla ngelixa ufumana unyango nge-temsirolimus.
• xelela ugqirha wakho ukuba zeziphi iimveliso zamayeza ozithathayo, ngakumbi iSort John's Wort.
• xelela ugqirha wakho ukuba ukhe unesifo seswekile, i-cholesterol ephezulu okanye i-triglycerides, ithumba kwinkqubo ye-nervous system (ingqondo okanye umnqonqo), umhlaza, okanye izintso, isibindi, okanye isifo semiphunga.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana i-temsirolimus kunye neenyanga ezintathu emva kokuba unyango nge-temsirolimus luphelile. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-temsirolimus, biza ugqirha wakho ngokukhawuleza. I-Temsirolimus inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngelixa ufumana i-temsirolimus.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana i-temsirolimus.
• Kuya kufuneka uyazi ukuba unokuba semngciphekweni wokufumana usulelo ngelixa ufumana i-temsirolimus. Qiniseka ukuba uhlamba izandla rhoqo kwaye uphephe ukunxibelelana nabantu abagulayo.
• awunalo ugonyo (umzekelo, imasisi, irhashalala, okanye umkhuhlane) ngaphandle kokuthetha nogqirha wakho.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa uthatha eli yeza.

Ukuba uphoswa idinga lokufumana idosi ye-temsirolimus, tsalela ugqirha kwangoko.

I-Temsirolimus inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubuthathaka
• ukudumba kwamehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• intloko ebuhlungu
• ukurhawuzelela, amanzi, okanye amehlo abomvu
• utshintsho kwindlela izinto ezingcamla ngayo
• ukudumba, ukuba bomvu, iintlungu, okanye izilonda ngaphakathi emlonyeni okanye emqaleni
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• isicaphucaphu
• ukugabha
• ukuqhina
• Ukufuna ukuchama rhoqo
• intlungu okanye ukutshisa ngexesha lokuchama
• igazi kumchamo
• umqolo obuhlungu
• intlungu yesihlunu okanye edibeneyo
• impumlo enegazi
• utshintsho kwiinzipho okanye iinzipho
• isikhumba esomileyo
• ulusu oluthuthu
• ukudinwa kakhulu
• ukubetha kwentliziyo okukhawulezayo
• induna
• ubunzima bokulala okanye ukulala
• ukudakumba

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukugungxula
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• ukuphefumla ngokukhawuleza okanye ukukhefuzela
• iintlungu zomlenze, ukudumba, ukuthamba, ubomvu, okanye ukufudumala
• ukunxanwa okugqithisileyo
• indlala enkulu
• umkhuhlane, umqala obuhlungu, Ukugodola, ukukhohlela, kunye neminye imiqondiso yosulelo
• isiqaqa
• Intlungu okanye isisu esibuhlungu
• urhudo
• Igazi elibomvu ilindle
• ukuncipha kwenani lomchamo
• ukungaboni kakuhle
• intetho ecothayo okanye enzima
• ukudideka
• isiyezi okanye ukudinwa
• ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze

I-Temsirolimus inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Eli yeza liya kugcinwa kwi-ofisi kagqirha okanye eklinikhi.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukuxhuzula
• i-hallucinating (ukubona izinto okanye ukuva amazwi angabikho)
• ubunzima bokucinga ngokucacileyo, ukuqonda inyani, okanye ukusebenzisa isigqibo esifanelekileyo
• ukukhohlela
• ukuqhawukelwa ngumphefumlo
• ifiva
• Intlungu okanye isisu esibuhlungu
• ukukhefuzela okanye ukuphefumla ngokukhawuleza
• Igazi elibomvu ilindle
• urhudo
• iintlungu zomlenze, ukudumba, ukuthamba, ubomvu, okanye ukufudumala

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-temsirolimus.

Buza ugqirha wakho ukuba unemibuzo malunga nonyango lwakho nge-temsirolimus.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UTorisel^®