Inaliti yeTacrolimus

Umxholo

• Ngaphambi kokufumana inaliti yetacrolimus,
• Inaliti yetacrolimus inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti yetacrolimus kufuneka inikwe kuphela phantsi kweliso likagqirha onamava ekunyangeni abantu abanokufakelwa amalungu kunye nokumisela amayeza anciphisa umsebenzi wamajoni omzimba.

Inaliti yetacrolimus inciphisa umsebenzi wamajoni akho omzimba. Oku kunokunyusa umngcipheko wokuba ufumane usulelo olubi. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngokukhawuleza: umqala obuhlungu; ukukhohlela; ifiva; ukudinwa kakhulu; iimpawu ezifana nomkhuhlane; ulusu olufudumeleyo, olubomvu, okanye olubuhlungu; okanye ezinye iimpawu zosulelo.

Xa amajoni akho omzimba engasebenzi ngesiqhelo, kunokubakho umngcipheko omkhulu wokuba ube nomhlaza, ngakumbi i-lymphoma (uhlobo lomhlaza oluqala kwiiseli zomzimba). Ngokude ufumana inaliti ye-tacrolimus okanye amanye amayeza anciphisa umsebenzi wamajoni omzimba, kunye nokuphakama kwamayeza akho ala mayeza, kokukhona lo mngcipheko unokunyuka. Ukuba ufumana naziphi na kwezi mpawu zilandelayo ze-lymphoma, biza ugqirha wakho ngokukhawuleza: i-lymph nodes ezivuvukileyo entanyeni, emakhwapheni, okanye kwi-groin; ukuhla ukusinda; ifiva; ukubila ebusuku; ukudinwa kakhulu okanye ubuthathaka; ukukhohlela; ingxaki yokuphefumla; iintlungu zesifuba; okanye iintlungu, ukudumba, okanye ukugcwala kwindawo yesisu.

Thetha nogqirha wakho malunga neengozi zokufumana inaliti yetacrolimus.

Inaliti yetacrolimus isetyenziswa kunye namanye amayeza ukunqanda ukwaliwa (ukuhlaselwa komzimba otshintshiweyo ngamajoni omzimba wokufumana umntu) kubantu abafumene izintso, isibindi okanye intliziyo. Inaliti yetacrolimus kufuneka isetyenziswe kuphela ngabantu abangakwaziyo ukuthatha itacrolimus ngomlomo. Inaliti yetacrolimus ikwiklasi yamayeza abizwa ngokuba zii-immunosupressants. Isebenza ngokunciphisa umsebenzi wamajoni omzimba ukukhusela ekuhlaseleni ilungu elifakelweyo.

Inaliti yetacrolimus iza njengesisombululo (ulwelo) sokutofelwa ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi esibhedlele okanye kwiziko lonyango. Ngokuqhelekileyo kunikwa ukunyuswa okuqhubekayo, ukuqala kungekudala kweeyure ezingama-6 emva kokuhlinzwa kunye nokuqhubeka de kube i-tacrolimus ingathathwa ngomlomo.

Ugqirha okanye umongikazi uya kukujonga ngokusondeleyo kwimizuzu yokuqala engama-30 yonyango lwakho kwaye emva koko uza kukujonga rhoqo ukuze unyangwe ngokukhawuleza ukuba uneempendulo ezimbi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti yetacrolimus,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-tacrolimus, nawaphi na amanye amayeza, i-polyoxyl 60 yeoyile ye-hydrogenated castor (HCO-60) okanye amanye amayeza aneoyile ye-castor. Buza ugqirha wakho okanye usokhemesti ukuba awazi ukuba amayeza onayo awanalo i-castor oil.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amphotericin B (Abelcet, Ambisome, Amphotec); Izichasi; I-antibiotics ethile kuquka i-aminoglycosides efana ne-amikacin, i-gentamicin, i-neomycin (i-Neo-Fradin), i-streptomycin, kunye ne-tobramycin (Tobi), kunye ne-macrolides ezifana ne-clarithromycin (i-Biaxin), i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin) kunye ne-troleandomycin (TAO) (ayifumaneki e-US); amayeza okubulala anjenge-clotrimazole (Lotrimin, Mycelex), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral) kunye ne-voriconazole (Vfend); bromocriptine (Parlodel); iicalcium block blockers ezinjenge diltiazem (Cardizem), nicardipine (Cardene), nifedipine (Adalat, Procardia), kunye neverapamil (Calan, Covera, Isoptin); iCaspofungin (Cancidas); ichloramphenicol; cimetidine (iTagamet); i-cisapride (Propulsid) (ayifumaneki e-U.S.); i-cisplatin (iPlatinol); iDanazol (iDanocrine); i-diuretics ethile ('iipilisi zamanzi'); ganciclovir (icytovene); izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufaka, okanye inaliti); I-HIV protease inhibitors efana ne-indinavir (Crixivan), nelfinavir (Viracept), kunye ne-ritonavir (Norvir); i-lansoprazole (Prevacid); amayeza athile okubanjwa njenge-carbamazepine (Tegretol), i-phenobarbital, kunye ne-phenytoin (iDilantin); imethylprednisolone (iMedrol); metoclopramide (Reglan); nefazodone; omeprazole (Prilosec); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane); kunye ne-sirolimus (Rapamune). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-tacrolimus, ngoko xelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ufumana okanye usandula ukuyeka ukufumana i-cyclosporine (Gengraf, Neoral, Sandimmune). Ukuba ubufumana i-cyclosporine, ugqirha wakho ngekhe aqale ukukunika inaliti ye-tacrolimus de kube ziiyure ezingama-24 emva kokuba ufumene idosi yokugqibela ye-cyclosporine. Ukuba uyeka ukufumana inaliti ye-tacrolimus, ugqirha wakho uyakukuxelela ukuba ulinde iiyure ezingama-24 ngaphambi kokuqala ukuthatha i-cyclosporine.
• xelela ugqirha wakho kunye nosokhemisti ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi i-wort yaseSt.
• xelela ugqirha wakho ukuba ukhe unesifo sentliziyo, sezintso, okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana inaliti ye-tacrolimus, tsalela ugqirha wakho.
• ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inaliti ye-tacrolimus.
• Kuya kufuneka uyazi ukuba ukufumana inaliti yetacrolimus kungonyusa umngcipheko wokuba ube nomhlaza wolusu. Zikhusele kumhlaza wolusu ngokuphepha ukukhanya elangeni okungafunekiyo okanye ixesha elide okanye ukukhanya kwe-ultraviolet (iibhedi zokutshisa) kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga esikhusela isikhumba (SPF).
• Kuya kufuneka uyazi ukuba inaliti ye-tacrolimus inokubangela uxinzelelo lwegazi oluphezulu. Ugqirha wakho uza kujonga uxinzelelo lwegazi ngononophelo, kwaye unokuyalela amayeza ukunyanga uxinzelelo lwegazi oluphezulu ukuba luyakhula.
• Kuya kufuneka uyazi ukuba kukho umngcipheko wokuba uya kuba nesifo seswekile ngexesha lonyango lwakho ngenaliti ye-tacrolimus. Izigulana zase-Afrika zaseMelika nezaseSpain eziye zafakelwa ukufakelwa kwezintso zinomngcipheko omkhulu wokuba nesifo seswekile ngexesha lonyango lwazo ngenaliti ye-tacrolimus. Tshela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho ukhe unesifo seswekile. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngokukhawuleza: ukunxanwa okugqithisileyo; ukulamba kakhulu; ukuchama rhoqo; ukungaboni kakuhle okanye ukudideka.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho.

Kuphephe ukutya igrapefruit okanye ukusela ijusi yegrapefruit ngelixa ufumana inaliti ye-tacrolimus.

Inaliti yetacrolimus inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ukushukuma okungalawulekiyo kwilungu lomzimba
• urhudo
• ukuqhina
• isicaphucaphu
• ukugabha
• isilungulela
• isisu esibuhlungu
• Ukuphelelwa ngumdla wokutya
• ubunzima bokulala okanye ukulala
• isiyezi
• ubuthathaka
• umqolo okanye iintlungu ezidibeneyo
• ukutshisa, ukuba ndindisholo, iintlungu okanye ukurhawuzelelwa zizandla okanye iinyawo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza:

• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukuncipha kokuchama
• intlungu okanye ukutshisa xa uchama
• ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukutyeba kwakho
• ukopha okungaqhelekanga okanye ukugruzuka
• ukuxhuzula
• isiqaqa (ukulahleka kwengqondo ixesha elithile)

Inaliti yetacrolimus inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• urhwebo
• ukozela

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwisitofu se-tacrolimus.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Prograf^®

• FK 506