Inaliti yeDexrazoxane
Umxholo
- Phambi kokuba ufumane inaliti ye-dexrazoxane,
- Inaliti yeDexrazoxane inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
- Iimpawu zokudlula ngaphezulu zinokubandakanya:
Inaliti yeDexrazoxane (iTotect, iZinecard) isetyenziselwa ukuthintela okanye ukunciphisa ukutyeba kwezihlunu zentliziyo ezibangelwa yi-doxorubicin kwabasetyhini abathatha amayeza ukunyanga umhlaza wamabele osasazeke kwamanye amalungu omzimba. Inaliti yeDexrazoxane (iTotect, iZinecard) inikwa kuphela abasetyhini abasele befumene isixa esithile se-doxorubicin kwaye ngubani oza kufuna unyango oluqhubekayo lwe-doxorubicin, ayisetyenziselwa ukuthintela ukonakala kwentliziyo kwabasetyhini abaqala unyango nge-doxorubicin. Inaliti ye-Dexrazoxane (Totect) isetyenziselwa ukunciphisa ukonakala kulusu nakwizicubu ezinokubangelwa xa amayeza e-anthracycline chemotherapy anje nge-daunorubicin (Cerubidine), doxorubicin (Adriamycin, Doxil), epirubicin (Ellence) okanye idarubicin (Idamycin) iyavuza umthambo njengoko utofwayo. Inaliti yeDexrazoxane ikwiiklasi zamayeza abizwa ngokuba zii-cardioprotectants kunye ne-chemoprotectants. Isebenza ngokumisa amayeza e-chemotherapy ekonakaliseni intliziyo kunye nezicubu.
Inaliti yeDexrazoxane iza njengomgubo oxutywe nolwelo kwaye itofwe emthanjeni ngugqirha okanye ngumongikazi esibhedlele. Xa inaliti ye-dexrazoxane isetyenziselwa ukuthintela ukonakala kwentliziyo okubangelwa yi-doxorubicin, inikwa ngaphezulu kwemizuzu eli-15 ngaphambi kwethamo ngalinye le-doxorubicin. Xa inaliti ye-dexrazoxane isetyenziselwa ukuthintela ukonakala kwethishu emva kokuba iyeza le-anthracycline liphumile emthanjeni, linikwa ngaphezulu kwe-1 ukuya kwiiyure ezimbini kanye ngemini kangangeentsuku ezi-3. Idosi yokuqala inikwa ngokukhawuleza kwiiyure zokuqala ezi-6 emva kokuvuza, kwaye idosi yesibini neyesithathu zinikwa malunga neeyure ezingama-24 kunye nama-48 emva kwethamo lokuqala.
Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.
Phambi kokuba ufumane inaliti ye-dexrazoxane,
- xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-dexrazoxane, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-dexrazoxane injection. Buza usokhemesti wakho uluhlu lwezithako.
- xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba uyayikhankanya imveliso ye-dimethylsulfoxide (DMSO).
- xelela ugqirha wakho ukuba ukhe unesifo sentliziyo, sezintso, okanye sesibindi.
- xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. Akufanele ukhulelwe ngelixa ufumana inaliti ye-dexrazoxane. Ukuba ufumana inaliti ye-dexrazoxane (iZinecard), kuya kufuneka usebenzise ulawulo lokuzalwa ngexesha lonyango lwakho. Ukuba ufumana inaliti ye-dexrazoxane (Totect), kuya kufuneka usebenzise ulawulo lokuzalwa ngexesha lonyango lwakho kwaye ubuncinci iinyanga ezi-6 emva kwedosi yakho yokugqibela. Ukuba uyindoda, wena neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye neenyanga ezi-3 emva kokuba uyeke ukufumana inaliti ye-dexrazoxane (Totect). Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana inaliti ye-dexrazoxane, tsalela ugqirha wakho. I-Dexrazoxane inokulimaza umbungu.
- xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa ufumana inaliti ye-dexrazoxane (Zinecard). Ukuba ufumana inaliti ye-dexrazoxane (Totect), akufuneki ukuba uncelise ibele ngelixa ufumana unyango kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
- Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuzala emadodeni. Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-dexrazoxane.
- ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inaliti ye-dexrazoxane.
- Kuya kufuneka uyazi ukuba unyango ngenaliti ye-dexrazoxane luyancipha kodwa aluphelisi umngcipheko wokuba i-doxorubicin iyonakalise intliziyo yakho. Ugqirha wakho usaya kufuneka akubeke esweni ngononophelo ukuze abone ukuba idoxorubicin iyichaphazele njani intliziyo yakho.
Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.
Inaliti yeDexrazoxane inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- iintlungu okanye ukudumba kwindawo apho lalifakwe khona iyeza
- isicaphucaphu
- ukugabha
- urhudo
- ukuqhina
- isisu esibuhlungu
- Ukuphelelwa ngumdla wokutya
- isiyezi
- intloko ebuhlungu
- ukudinwa kakhulu
- ubunzima bokulala okanye ukulala
- ukudakumba
- ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
- umqala obuhlungu, umkhuhlane, Ukugodola, ukukhohlela, kunye neminye imiqondiso yosulelo
- ukugruzuka okanye ukopha okungaqhelekanga
- ulusu oluthuthu
- ubuthathaka
- ukuqhawukelwa ngumphefumlo
- irhashalala
- ukurhawuzelela
- urhwebo
- ubunzima bokuphefumla okanye ukugwinya
- ukudumba kwamehlo, ubuso, umlomo, imilebe, ulwimi, okanye umqala
- isiyezi
- isiqaqa
Abanye abantu abathathe iyeza elifana kakhulu nenaliti ye-dexrazoxane bavelise iindlela ezintsha zomhlaza. Akukho lwazi lwaneleyo ukuxelela ukuba ukufumana inaliti ye-dexrazoxane kwandisa umngcipheko wokuba uza kuvelisa uhlobo olutsha lomhlaza. Thetha nogqirha wakho malunga neengozi zokufumana eli yeza.
Inaliti yeDexrazoxane inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.
Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).
Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.
Iimpawu zokudlula ngaphezulu zinokubandakanya:
- umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
- ukugruzuka okanye ukopha okungaqhelekanga
- ulusu oluthuthu
- ukuqhawukelwa ngumphefumlo
- ukudinwa kakhulu
Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-dexrazoxane injection.
Buza ugqirha wakho okanye usokhemesti nayiphi na imibuzo onayo malunga nenaliti ye-dexrazoxane.
Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.
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